Aliases for IFI27 Gene
External Ids for IFI27 Gene
Previous GeneCards Identifiers for IFI27 Gene
GeneCards Summary for IFI27 Gene
IFI27 (Interferon Alpha Inducible Protein 27) is a Protein Coding gene. Diseases associated with IFI27 include Lung Clear Cell Carcinoma and Newcastle Disease. Among its related pathways are Immune response IFN alpha/beta signaling pathway and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include RNA polymerase II activating transcription factor binding and lamin binding. An important paralog of this gene is IFI27L2.
UniProtKB/Swiss-Prot for IFI27 Gene
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.