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Aliases for IER5L Gene

Aliases for IER5L Gene

  • Immediate Early Response 5-Like 2 3
  • Immediate Early Response Gene 5-Like Protein 3
  • BA247A12.2 3

External Ids for IER5L Gene

Summaries for IER5L Gene

GeneCards Summary for IER5L Gene

IER5L (Immediate Early Response 5-Like) is a Protein Coding gene. An important paralog of this gene is IER5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IER5L Gene

Genomics for IER5L Gene

Genomic Location for IER5L Gene

Start:
129,175,552 bp from pter
End:
129,178,262 bp from pter
Size:
2,711 bases
Orientation:
Minus strand

Genomic View for IER5L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IER5L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IER5L Gene

Regulatory Elements for IER5L Gene

Proteins for IER5L Gene

  • Protein details for IER5L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T953-IER5L_HUMAN
    Recommended name:
    Immediate early response gene 5-like protein
    Protein Accession:
    Q5T953
    Secondary Accessions:
    • Q6P3E2

    Protein attributes for IER5L Gene

    Size:
    404 amino acids
    Molecular mass:
    42109 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IER5L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IER5L Gene

Proteomics data for IER5L Gene at MOPED

Post-translational modifications for IER5L Gene

No Post-translational modifications

Other Protein References for IER5L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IER5L Gene

Domains for IER5L Gene

Protein Domains for IER5L Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

IER5L_HUMAN
Family:
  • Belongs to the IER family.:
    • Q5T953
genes like me logo Genes that share domains with IER5L: view

No data available for Gene Families for IER5L Gene

Function for IER5L Gene

Phenotypes for IER5L Gene

GenomeRNAi human phenotypes for IER5L:
genes like me logo Genes that share phenotypes with IER5L: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IER5L Gene

Localization for IER5L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IER5L Gene COMPARTMENTS Subcellular localization image for IER5L gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for IER5L Gene

Pathways for IER5L Gene

SuperPathways for IER5L Gene

No Data Available

Interacting Proteins for IER5L Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000361569%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000361569 for IER5L Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for IER5L Gene

None

No data available for Pathways by source for IER5L Gene

Transcripts for IER5L Gene

mRNA/cDNA for IER5L Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(123) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IER5L Gene

Immediate early response 5-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IER5L Gene

No ASD Table

Relevant External Links for IER5L Gene

GeneLoc Exon Structure for
IER5L
ECgene alternative splicing isoforms for
IER5L

Expression for IER5L Gene

mRNA expression in normal human tissues for IER5L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for IER5L Gene

SOURCE GeneReport for Unigene cluster for IER5L Gene Hs.529857

genes like me logo Genes that share expressions with IER5L: view

Orthologs for IER5L Gene

This gene was present in the common ancestor of chordates.

Orthologs for IER5L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia IER5L 36
  • 92.93 (n)
  • 90.4 (a)
IER5L 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IER5L 36
  • 93.23 (n)
  • 90.98 (a)
IER5L 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ier5l 36
  • 92.56 (n)
  • 92.73 (a)
Ier5l 16
Ier5l 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IER5L 37
  • 48 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ier5l 36
  • 92.58 (n)
  • 92 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.33398 36
tropical clawed frog
(Silurana tropicalis)
Amphibia ier5l 36
  • 74.83 (n)
  • 76 (a)
MGC75980 36
zebrafish
(Danio rerio)
Actinopterygii ier5l 36
  • 68.46 (n)
  • 74.51 (a)
ier5l 37
  • 52 (a)
OneToOne
wufe50b07 36
Species with no ortholog for IER5L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IER5L Gene

ENSEMBL:
Gene Tree for IER5L (if available)
TreeFam:
Gene Tree for IER5L (if available)

Paralogs for IER5L Gene

Paralogs for IER5L Gene

genes like me logo Genes that share paralogs with IER5L: view

Variants for IER5L Gene

Sequence variations from dbSNP and Humsavar for IER5L Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs184457 - 129,177,740(+) GGCCG(A/G)CTCGC reference, missense
rs401003 -- 129,177,864(-) cagca(A/C)cagca reference, missense
rs449770 -- 129,177,870(-) cagca(C/G)cagca missense, reference
rs882616 -- 129,178,586(-) CTCCC(A/G)GGACC upstream-variant-2KB
rs1075650 -- 129,176,634(-) CAGAG(A/G)GAAAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for IER5L Gene

Variant ID Type Subtype PubMed ID
nsv818725 CNV Gain 17921354
nsv893909 CNV Loss 21882294
nsv825108 CNV Gain 20364138
nsv825110 CNV Gain 20364138
nsv825111 CNV Gain 20364138
esv2675916 CNV Deletion 23128226
nsv466578 CNV Loss 19166990

Relevant External Links for IER5L Gene

HapMap Linkage Disequilibrium report
IER5L

Disorders for IER5L Gene

No disorders were found for IER5L Gene.

No data available for UniProtKB/Swiss-Prot for IER5L Gene

Publications for IER5L Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  5. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3

Products for IER5L Gene

Sources for IER5L Gene

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