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Aliases &
Descriptions
for IER3IP1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| HSPC039 2 | | PRO2309 2 |
| | | Descriptions |
|---|
| immediate early response 3 interacting protein 1 2 |
|
| |
Search outside databases for aliases for IER3IP1 gene |
Summaries
for IER3IP1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9Function: May be involved in protein transport between endoplasmic reticulum and Golgi apparatus
(By similarity)Gene Wiki entry for IER3IP1 |
Genomic Location
for IER3IP1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the IER3IP1 gene 
Entrez Gene cytogenetic band: 18q12 Ensembl cytogenetic band: 18q21.1 HGNC cytogenetic band: 18q12IER3IP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18M042935:
(about GC identifiers)
Start:
|
42,935,411 bp from pter |
End:
|
42,956,743 bp from pter |
Size:
|
21,333 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000018.8 NT_010966.13
| Proteins
for IER3IP1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9 (See
protein sequence)Recommended Name: Immediate early response 3-interacting protein 1 Size: 82 amino acids; 8969 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane proteinREFSEQ proteins: NP_057181.1
ENSEMBL proteins: ENSP00000256433
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
5 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for IER3IP1:
Assays for IER3IP1: | Protein
Domains/
Families
for IER3IP1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9Y5U9
ProtoNet protein and cluster: Q9Y5U9 1 Blocks protein family: IPB013880 Yos1-like
UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9Similarity: Belongs to the YOS1 family | Gene Function
for IER3IP1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016097
 Applied Biosystems Silencer® siRNAs for IER3IP1
 Sigma-Aldrich siRNA for IER3IP1
Sigma-Aldrich shRNA for IER3IP1
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_016097
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016097
untagged cDNA clone in CMV expression vector: NM_016097
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_016097
UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9Function: May be involved in protein transport between endoplasmic reticulum and Golgi apparatus
(By similarity) | Pathways & Interactions
for IER3IP1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Interacting protein for IER3IP1 (ENSP000002564333) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for IER3IP1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for IER3IP1
|
Transcripts
for IER3IP1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_016097
Sigma-Aldrich siRNA for IER3IP1
Sigma-Aldrich shRNA for IER3IP1
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_016097 REFSEQ mRNAs for IER3IP1 gene: NM_016097.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_016097
OriGene GFP tagged cDNA clone in CMV expression vector: NM_016097
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016097
untagged cDNA clone in CMV expression vector: NM_016097
Additional cDNA sequence: AF164798.1 AF371963.1 AK027108.1 AL136667.1 BC010888.1 BC017391.1 CR533488.1 CR596209.1 CR596950.1 CR599998.1 CR614259.1 9 DOTS entries: DT.451736 DT.95131567 DT.100818899 DT.99976796 DT.121102368 DT.121102290 DT.121102293 DT.95131563 DT.121102289 24/521 AceView cDNA sequences (see all 521
):AA332479 BC038100 AW058520 BM724496 NM_016097 AW612673 BU743002 AI857347 AA995061 NM_032124 BM670439 AI628771 F12760 BM692728 AA932320 CA433667 AL136681 BF244066 BQ425962 AA257967 BX339575 AW189463 AI653244 CR596274
 highest scoring ESTs for IER3IP1:AA165168 AA451992 AA494459 AA587229 AA853098 AF164798 AF371963 AI755071 AK027108 AL136667 Unigene Cluster for IER3IP1: Immediate early response 3 interacting protein 1 Hs.653122 [show with all ESTs]Unigene Representative Sequence: AK027108
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000256433
|
Expression
for IER3IP1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| IER3IP1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for IER3IP1
1 / 2 / 3 5 probe-sets matching IER3IP1 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.653122
UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9Tissue specificity: Highest levels in heart, skeletal muscle, and kidney |
Orthologs
for IER3IP1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for IER3IP1 gene from 5/9 species (see all 9
)
About this table Species with no ortholog for IER3IP1
ENSEMBL Gene Tree for IER3IP1 | Paralogs
for IER3IP1(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Pseudogenes
- 1 related pseudogene
|
SNPs/Variants
for IER3IP1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for IER3IP1 (up to first 250kb)
|
Disorders & Mutations
for IER3IP1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 609382
|
Medical News
for IER3IP1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for IER3IP1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 9 PubMed articles for IER3IP1 gene:- Cloning and characterization of a novel endoplasmic reticulum localized G-patch domain protein, IER3IP1. (PubMed id 15276200)1, 2, 3, 4 Yiu W.H.... Waye M.M.Y. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)3, 4 Wiemann S.... Poustka A. (2001)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)3, 4 Hu R.-M.... Chen J.-L. (2000)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)3, 4 Zhang Q.H....Chen Z. (2000)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)3 Barbe L....Andersson-Svahn H. (2008)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)3 Oh J.H....Kim N.S. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)3 Simpson J.C.... Wiemann S. (2000)
|
Search for IER3IP1
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IER3IP1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing IER3IP1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IER3IP1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for IER3IP1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for IER3IP1:
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| | |  | Search Tocris compounds for IER3IP1 |
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