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IER3IP1 Gene

protein-coding   GIFtS: 50
GCID: GC18M044681

Immediate Early Response 3 Interacting Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Immediate Early Response 3 Interacting Protein 11 2
MEDS2 5
PRO23092
Immediate Early Response 3-Interacting Protein 12

External Ids:    HGNC: 185501   Entrez Gene: 511242   Ensembl: ENSG000001340497   OMIM: 6093825   UniProtKB: Q9Y5U93   

Export aliases for IER3IP1 gene to outside databases

Previous GC identifers: GC18M042935 GC18M041529


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IER3IP1 Gene:
This gene encodes a small protein that is localized to the endoplasmic reticulum (ER) and may play a role in the
ER stress response by mediating cell differentiation and apoptosis. Transcription of this gene is regulated by
tumor necrosis factor alpha and specificity protein 1 (Sp1). Mutations in this gene may play a role in
microcephaly, epilepsy, and diabetes syndrome (MEDS), and a pseudogene of this gene is located on the long arm of
chromosome 12. (provided by RefSeq, Dec 2011)

GeneCards Summary for IER3IP1 Gene:
IER3IP1 (immediate early response 3 interacting protein 1) is a protein-coding gene. Diseases associated with IER3IP1 include microcephaly, epilepsy, and diabetes syndrome, and microcephaly. An important paralog of this gene is ENSG00000267228.

UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9
Function: May be implicated in the regulation of apoptosis. May be involved in protein transport between
endoplasmic reticulum and Golgi apparatus (By similarity)

Gene Wiki entry for IER3IP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000018.10  NC_018929.2  NT_010966.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the IER3IP1 gene promoter:
         Pax-2   FOXD1   Pax-2a   E47   GATA-2   Max   FOXC1   Pax-2b   Hand1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIER3IP1 promoter sequence
   Search Chromatin IP Primers for IER3IP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IER3IP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12   Ensembl cytogenetic band:  18q21.1   HGNC cytogenetic band: 18q12

IER3IP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IER3IP1 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M044681:  view genomic region     (about GC identifiers)

Start:
44,681,413 bp from pter      End:
44,702,745 bp from pter
Size:
21,333 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9 (See protein sequence)
Recommended Name: Immediate early response 3-interacting protein 1  
Size: 82 amino acids; 8969 Da

Explore the universe of human proteins at neXtProt for IER3IP1: NX_Q9Y5U9

Explore proteomics data for IER3IP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys29
  • Modification sites at PhosphoSitePlus

  • See IER3IP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057181.1  
    ENSEMBL proteins: 
     ENSP00000256433  

    IER3IP1 Human Recombinant Protein Products:

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    IER3IP1 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013880 Yos1

    Graphical View of Domain Structure for InterPro Entry Q9Y5U9

    ProtoNet protein and cluster: Q9Y5U9

    1 Blocks protein domain: IPB013880 Yos1-like

    UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9
    Similarity: Belongs to the YOS1 family


    IER3IP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IR3IP_HUMAN, Q9Y5U9
    Function: May be implicated in the regulation of apoptosis. May be involved in protein transport between
    endoplasmic reticulum and Golgi apparatus (By similarity)

    Phenotypes:
         2 GenomeRNAi human phenotypes for IER3IP1:

     Actin fiber cells  Increased homologous recombina 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IER3IP1
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    miRNA
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    miRTarBase miRNAs that target IER3IP1:
    hsa-mir-423-3p (MIRT042636), hsa-mir-10a-5p (MIRT025593), hsa-mir-155-5p (MIRT020890), hsa-mir-92a-3p (MIRT049035), hsa-mir-19b-3p (MIRT031248), hsa-mir-130b-3p (MIRT020300), hsa-mir-107 (MIRT026976), hsa-mir-16-5p (MIRT051283)

    Block miRNA regulation of human, mouse, rat IER3IP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IER3IP1 (see all 26):
    hsa-miR-3607-5p hsa-miR-125a-5p hsa-miR-136 hsa-miR-520d-5p hsa-miR-4251 hsa-miR-301a hsa-miR-519a hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidIER3IP1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IER3IP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IR3IP_HUMAN, Q9Y5U9: Endoplasmic reticulum membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus4
    extracellular3
    plasma membrane2
    cytoskeleton1
    cytosol1
    lysosome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005794Golgi apparatus IDA--
    GO:0016021integral component of membrane IEA--

    IER3IP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IER3IP1
    Interactions:

        Search GeneGlobe Interaction Network for IER3IP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for IER3IP1 (Q9Y5U92, 3 ENSP000002564334) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678702, 3MINT-8253330 I2D: score=2 
    ENSG00000206406P678702, 3MINT-8253330 I2D: score=2 
    ENSG00000224398P678702, 3MINT-8253330 I2D: score=2 
    ENSG00000224774P678702, 3MINT-8253330 I2D: score=2 
    ENSG00000228875P678702, 3MINT-8253330 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:2000269regulation of fibroblast apoptotic process IMP--

    IER3IP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IER3IP1 (IR3IP)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IER3IP1 gene: 
    NM_016097.4  

    Unigene Cluster for IER3IP1:

    Immediate early response 3 interacting protein 1
    Hs.130917  [show with all ESTs]
    Unigene Representative Sequence: NM_016097
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000256433(uc002lcu.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat IER3IP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IER3IP1 (see all 26):
    hsa-miR-3607-5p hsa-miR-125a-5p hsa-miR-136 hsa-miR-520d-5p hsa-miR-4251 hsa-miR-301a hsa-miR-519a hsa-miR-29b-1*
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    GenScript: all cDNA clones in your preferred vector: IER3IP1 (NM_016097)
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat IER3IP1
      QuantiFast Probe-based Assays in human, mouse, rat IER3IP1

    Additional mRNA sequence: 

    AF164798.1 AF371963.1 AK027108.1 AL136667.1 BC010888.1 BC017391.1 CR533488.1 

    8 DOTS entries:

    DT.451736  DT.95131567  DT.100818899  DT.99976796  DT.121102368  DT.121102290  DT.121102293  DT.95131563 

    Selected AceView cDNA sequences (see all 521):

    AA257968 BP374100 BQ232756 BU743002 AW130276 Z40188 AI800300 AA995061 
    BU182007 AW963037 AA932320 AW665087 AI589122 AI184583 BE501762 AI249724 
    AL539944 CB243242 NM_016097 BU675399 BM724496 BX379497 R29208 AW073404 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IER3IP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IER3IP1 Expression
    About this image


    IER3IP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    IER3IP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IER3IP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.130917

    UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9
    Tissue specificity: Highest levels in heart, skeletal muscle, and kidney

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IER3IP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for IER3IP1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ier3ip11 , 5 immediate early response 3 interacting protein 11, 5 91.06(n)1
    97.56(a)1
      18 (51.98 cM)5
    661911  NM_025409.31  NP_079685.11 
     769300175 
    chicken
    (Gallus gallus)
    Aves IER3IP11 immediate early response 3 interacting protein 1 76.83(n)
    84.15(a)
      101749130  XM_004949020.1  XP_004949077.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.108982 Xenopus laevis transcribed sequence with moderate similarity more 80.6(n)    AU244785.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570378272   -- 78.16(n)    57037827 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG320696
    --
    54(a)
    1 → many
    3L(11055231-11055714)
    worm
    (Caenorhabditis elegans)
    Secernentea W09G3.86
    Protein W09G3.8 (W09G3.8) mRNA, complete cds
    50(a)
    1 → many
    I(13812135-13814355) WBGene00012371
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YOS16
    Integral membrane protein required for ER to Golgi...
    42(a)
    1 → many
    V(307653-308123) YER074W-A


    ENSEMBL Gene Tree for IER3IP1 (if available)
    TreeFam Gene Tree for IER3IP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IER3IP1 gene
    ENSG000002672282  

    IER3IP1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for IER3IP1
    PGOHUM00000239581 PGOHUM00000243166


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IER3IP1 (see all 422)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0665704
    Microcephaly, epilepsy, and diabetes syndrome (MEDS)4--see VAR_0665702 L P mis40--------
    VAR_0665694
    Microcephaly, epilepsy, and diabetes syndrome (MEDS)4--see VAR_0665692 V G mis40--------
    rs347234001,2
    C--41539931(+) GTCTCAA/-AAAAA 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1837443771,2
    --44676839(+) TACCAC/TATGGG 1 -- ds50010--------
    rs1450802851,2
    --44676868(+) AGTAAC/TTGCTT 1 -- ds50010--------
    rs1870352921,2
    --44676873(+) CTGCTG/TCTTTT 1 -- ds50010--------
    rs1388547611,2
    --44676966(+) AGTCAC/TTCACA 1 -- ds50010--------
    rs739542421,2
    C,F--44677030(+) GCCTAC/TAGTCC 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs729072801,2
    C--44677044(+) GATCAC/TTGATC 1 -- ds50014Minor allele frequency- T:0.10NA WA EA 360
    rs22519481,2
    C,F,O,A,H--44677270(-) CTCCAT/ATTTGG 1 -- ds500116Minor allele frequency- A:0.32NS EA NA WA 926

    HapMap Linkage Disequilibrium report for IER3IP1 (44681413 - 44702745 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for IER3IP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv909613CNV Loss21882294
    nsv833640CNV Loss17160897
    nsv909612CNV Gain21882294
    nsv9629CNV Gain+Loss18304495

    Human Gene Mutation Database (HGMD): IER3IP1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IER3IP1
    DNA2.0 Custom Variant and Variant Library Synthesis for IER3IP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 609382   
    OMIM disorders: 614231  
    UniProtKB/Swiss-Prot: IR3IP_HUMAN, Q9Y5U9
  • Microcephaly, epilepsy, and diabetes syndrome (MEDS) [MIM:614231]: An autosomal recessive disorder
    characterized by microcephaly, simplified gyral pattern, severe epilepsy, and infantile diabetes. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • 8 diseases for IER3IP1:    
    About MalaCards
    microcephaly, epilepsy, and diabetes syndrome    microcephaly    tonsillitis    multiple myeloma
    myeloma    cerebritis    thyroiditis    prostatitis

    1 disease from the University of Copenhagen DISEASES database for IER3IP1:
    Microcephaly

    IER3IP1 for disorders           About GeneDecksing


    Export disorders for IER3IP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IER3IP1 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with IER3IP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel endoplasmic reticulum localized G-patch domain protein, IER3IP1. (PubMed id 15276200)1, 2, 3, 9 Yiu W.H.... Waye M.M.Y. (Gene 2004)
    2. Microcephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitors. (PubMed id 21835305)1, 2 Poulton C.J....Mancini G.M. (Am. J. Hum. Genet. 2011)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    6. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    7. Transcriptional regulation of IER3IP1 gene by tumor necrosis factor-alpha and Sp family proteins. (PubMed id 19885854)1, 9 Yiu W.H....Waye M.M. (Cell Biochem. Funct. 2010)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. A homozygous IER3IP1 mutation causes microcephaly with simplified gyral pattern, epilepsy, and permanent neonatal diabetes syndrome (MEDS). (PubMed id 22991235)1 Abdel-Salam G.M....Gleeson J.G. (Am. J. Med. Genet. A 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51124 HGNC: 18550 AceView: IER3IP1andHDHD2 Ensembl:ENSG00000134049 euGenes: HUgn51124
    ECgene: IER3IP1 H-InvDB: IER3IP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for IER3IP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IER3IP1 gene:
    Search GeneIP for patents involving IER3IP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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