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IER3 Gene

protein-coding GIFtS: 54

GC06M030818

immediate early response 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DIF-2 ^¹, ²
DIF2 ^², ³, ⁵
GLY96 ^², ⁵
IEX-1 ^¹, ²
IEX-1L ^¹, ²
IEX1 ^², ³, ⁵
OTTHUMP00000029400 ^²
PRG1 ^¹, ², ³, ⁵

Descriptions
Differentiation-dependent gene 2 protein ^³
Immediate early protein GLY96 ^³
Immediate early response 3 protein ^³
PACAP-responsive gene 1 ^²
PACAP-responsive gene 1 protein ^³
Protein DIF-2 ^³
Protein PRG1 ^³
anti-death protein ^²
differentiation-dependent gene 2 ^²
expressed in pancreatic carcinoma ^²
gly96, mouse, homolog of ^²
immediate early response 3 ^²
immediately early gene X-1 ^²
radiation-inducible immediate-early gene IEX-1 ^²

External Ids
HGNC: 5392¹
Entrez Gene: 8870²
UniProtKB: P46695³
Ensembl: ENSG00000137331⁷

Search outside databases for aliases for IER3 gene

Previous GC identifers: GC06M030766 GC06M030481 GC06M030817

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for IER3:

This gene functions in the protection of cells from Fas- or tumor necrosis factor type

alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus

infection in vitro, but these transcripts are not found in vivo and do not generate a valid

protein. [provided by RefSeq]

Gene Wiki entry for IER3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the IER3 gene

Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.33 HGNC cytogenetic band: 6p21.3

IER3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M030818: (about GC identifiers)

Start:	30,818,955 bp from pter
End:	30,820,306 bp from pter
Size:	1,352 bases
Orientation:	minus strand

2 alternative locations:

Chr6-,c6_QBL 30,843,361-30,844,716

Chr6-,c6_COX 30,848,095-30,849,450

RefSeq DNA sequence:

NC_000006.10 NT_007592.14 NT_113891.1 NT_113893.1

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: IEX1_HUMAN, P46695 (See protein sequence)

Recommended Name: Radiation-inducible immediate-early gene IEX-1

Size: 156 amino acids; 16929 Da

Subcellular location: Membrane; Single-pass type II membrane protein (Potential)

Secondary accessions: Q92691 Q93044

Post-translational modifications:

Glycosylated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_003888.2

ENSEMBL proteins:

ENSP00000365557 ENSP00000365562 ENSP00000259874

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (IEX1)
	Human Recombinant Proteins from Abnova (IER3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for IER3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for IER3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (IEX1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for IER3

Assays for IER3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: P46695

UniProtKB/Swiss-Prot: IEX1_HUMAN, P46695

Similarity: Belongs to the IER3 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IER3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_052815

Applied Biosystems Silencer® siRNAs for IER3

Sigma-Aldrich siRNA for IER3

Sigma-Aldrich shRNA for IER3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for IER3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003897
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003897
untagged cDNA clones in CMV expression vector (see all 2): NM_003897

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003897

UniProtKB/Swiss-Prot: IEX1_HUMAN, P46695

Induction: By radiation, TPA, okadaic acid and TNF-alpha

Genatlas biochemistry entry for IER3:

immediate early gene induced by ionizing radiation and activators of PRKC,including a shorter

(IEX-S) and a larger non spliced isoform (IEX-L) the later inhibiting apoptosis involved in NFKB

mediate survival cell

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ier3):

muscle

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15451437

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for IER3

5/11 Interacting proteins for IER3 (ENSP00000365562³ P46695^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MAPK1	P28482²	STRING (score=.903) MINT-2835582
CAMLG	P49069¹	EBI-1748945, EBI-1748958
PPP2R5B	Q15173²	MINT-2835538 MINT-2835492 MINT-2835515 MINT-2835371
PPP2CA	P67775²	MINT-2835686 MINT-2835661
PPP2R5C	Q13362²	MINT-2835469 MINT-2835420

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptosis	TAS	9196025
GO:0006916	anti-apoptosis	TAS	9703517
GO:0009653	anatomical structure morphogenesis	TAS	9196025

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for IER3

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IER3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_052815

Sigma-Aldrich siRNA for IER3

Sigma-Aldrich shRNA for IER3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003897

REFSEQ mRNAs for IER3 gene:

NM_003897.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003897

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003897
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003897
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_003897

Additional cDNA sequence:

AF039067.1 AF083421.1 AK222588.1 AK314162.1 BC000844.2 BC005080.1 BT006703.1 CR594838.1

CR594999.1 CR599121.1 CR599601.1 CR605389.1 CR613281.1 CR625889.1 S81914.1 Y14551.1

19 DOTS entries:

DT.418090 DT.100839835 DT.100839846 DT.92326984 DT.40116205 DT.100834870 DT.102824035 DT.100839845

DT.121370704 DT.100838072 DT.97791426 DT.97855230 DT.99986295 DT.100839839 DT.100839842 DT.121370890

DT.91638085 DT.121370878 DT.92443683

21 AceView cDNA sequences:

CR594838 BC005080 CR613281 CR599121 CR599601 CR625889 CR605389 BC000844

CR594999 AF083421 AF039067 Y14551 BV177387 NM_052815 NM_003897 BT006703

S81914 CD617661 AJ227914 BG946513 BG946500

highest scoring ESTs for IER3:

S81914 AA043424 AA143404 AA356940 AA410666 AA480815 AF039067 AF083421 AI824906 BC000844

Unigene Cluster for IER3:

Immediate early response 3

Hs.591785 [show with all ESTs]

Unigene Representative Sequence: BM906591

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000376377 ENST00000376382 ENST00000259874

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

IER3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IER3

¹ / ² / ³

3 probe-sets matching IER3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1237_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	S81914	1.00	1.00	1.00	1
201631_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003897	0.60	1.00	0.82	1
201631_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks IER3 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACCATCCTGC

SOURCE GeneReport for Unigene cluster: Hs.591785
Expression variation in blood from EXPOLDB for IER3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IER3 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	IER3¹	--	immediate early response 3	83.97(n) 78.21(a)	481708 XM_538829.2 XP_538829.1
chimpanzee (Pan troglodytes)	IER3¹	--	immediate early response 3	99.57(n) 98.72(a)	743437 XM_001149799.1 XP_001149799.1
cow (Bos taurus)	IER3¹	--	immediate early response 3	85.9(n) 80.77(a)	505455 NM_001075202.1 NP_001068670.1
rat (Rattus norvegicus)	Ier3¹	--	immediate early response 3	79.06(n) 76.28(a)	294235 NM_212505.1 NP_997670.1
mouse (Mus musculus)	Ier3^{1, 5}	17⁵	immediate early response 3^{1, 5}	78.35(n)¹ 75.32(a)¹	15937¹ NM_133662.2¹ NP_598423.1¹ AI663993⁵ AK003466⁵ (see all 13)

About this table Species with no ortholog for IER3

ENSEMBL Gene Tree for IER3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/12 NCBI SNPs in IER3 are shown (see all 12 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs2284174^1,2	A,C,F,H	30821559(+)	`agaatT/Ctaaaa`	1	--	ng3¹		10		EA EU WA NS	2502
--	rs2284173^1,2	A,C,F	30821275(+)	`gatgcG/Agctgg`	1	--	ng3¹		1		EA	1490
--	rs3130662^1,2	A,C	30821787(+)	`gaatgA/Caatcc`	1	--	ng3¹		0	--	--	--	--
--	rs6931296^1,2	A,C	30821310(+)	`ctcagC/Gaacag`	1	--	ng3¹		0	--	--	--	--
--	rs58638768^1,2	--	30821409(+)	`GACCAC/GTAGAA`	1	--	ng3¹		0	--	--	--	--
--	rs72164422^1,2	--	30822305(+)	`GGCTA-/ATA TATATATATA`	1	--	ng3¹		0	--	--	--	--
--	rs9468822^1,2	--	30820445(+)	`GGAGAC/TTTGAC`	1	--	ng3¹		0	--	--	--	--
--	rs3757338^1,2	--	30820747(+)	`gcacgC/Tgccac`	1	--	ng3¹		0	--	--	--	--
--	rs9468823^1,2	--	30822152(+)	`ttttgA/Cgacag`	1	--	ng3¹		0	--	--	--	--
--	rs34937798^1,2	--	30821796(+)	`CCTGG-/AAAAAA`	1	--	ng3¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for IER3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602996

6 Novoseek disease relationships for IER3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tumors	14.45	21	11844788 (2), 17704804 (2), 18026799 (2), 8603392 (2) (see all 10)
necrosis	10.52	8	8603392 (2), 9791001 (1), 16528364 (1), 17538120 (1) (see all 6)
hyperplasia	0.00	1	15451437 (1)
cancer	0.00	3	15087407 (2)
breast cancer	0.00	2	15102447 (1), 15120418 (1)
prostate cancer	0.00	1	14656475 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/82 PubMed articles for IER3 gene (see all 82 ):

Identification and characterization of a radiation-inducible glycosylated human early-response gene. (PubMed id 8603392)^{1, 2, 3, 4} Kondratyev A.D.... Jung M.O. (1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. (PubMed id 9703517)^{2, 3} Wu M.X....Schlossman S.F. (1998)
Identification and characterization of a novel monocyte/macrophage differentiation-dependent gene that is responsive to lipopolysaccharide, ceramide, and lysophosphatidylcholine. (PubMed id 9196025)^{3, 4} Pietzsch A.... Schmitz G. (1997)
PRG1: a novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell line. (PubMed id 8653710)^{3, 4} Schaefer H.... Schmidt W.E. (1996)
Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancer. (PubMed id 18026799)^{1, 3} Sasada T....Takabayashi A. (2008)
IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation. (PubMed id 12356731)^{1, 3} Garcia J....Porteu F. (2002)
Immediate early gene X1 (IEX-1) is organized in subnuclear structures and partially co-localizes with promyelocytic leukemia protein in HeLa cells. (PubMed id 15855159)^{1, 3} Kruse M.L....Schafer H. (2005)
Regulation of a novel immediate early response gene, IEX-1, in keratinocytes by 1alpha,25-dihydroxyvitamin D3. (PubMed id 9791001)^{1, 3} Kobayashi T....Kumar R. (1998)
The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition. (PubMed id 17704804)^{1, 3} Sebens Muerkoster S....Arlt A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8870	HGNC: 5392	AceView: IER3	Ensembl:ENSG00000137331	euGenes: HUgn8870
ECgene: IER3	H-InvDB: IER3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for IER3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for IER3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for IER3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for IER3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IER3		Antibodies for IER3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for IER3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (IER3)
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	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (IEX1)
	Antibodies (IEX1)

Search OriGene for IER3

Search Tocris compounds for IER3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for IER3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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IER3 Gene at Home site.
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IER3 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for IER3

Summaries
for IER3

Genomic Location
for IER3

Proteins
for IER3

Protein Domains/
Families
for IER3

Gene Function
for IER3

Pathways & Interactions
for IER3

Drugs & Compounds
for IER3

Transcripts
for IER3

Expression
for IER3

Orthologs
for IER3

Paralogs
for IER3

SNPs/Variants
for IER3

Disorders & Mutations
for IER3

Medical News
for IER3

Publications
for IER3

Search for IER3

Genome Databases showing IER3

Other Databases showing IER3

Specialized Databases showing IER3

Licensable Technologies
for IER3

Services
for IER3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IER3 (Gene Symbol)
DIF-2
DIF2
GLY96
IEX-1
IEX-1L
IEX1
OTTHUMP00000029400
PRG1
Differentiation-dependent gene 2 protein
Immediate early protein GLY96
Immediate early response 3 protein
PACAP-responsive gene 1
PACAP-responsive gene 1 protein
Protein DIF-2
Protein PRG1
anti-death protein
differentiation-dependent gene 2
expressed in pancreatic carcinoma
gly96, mouse, homolog of
immediate early response 3
immediately early gene X-1
radiation-inducible immediate-early gene IEX-1

IER3 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor IER3

Summariesfor IER3

Genomic Locationfor IER3

Proteinsfor IER3

Protein Domains/Familiesfor IER3

Gene Functionfor IER3

Pathways & Interactionsfor IER3

Drugs & Compoundsfor IER3

Transcriptsfor IER3

Expression for IER3

Orthologsfor IER3

Paralogsfor IER3

SNPs/Variantsfor IER3

Disorders & Mutationsfor IER3

Medical Newsfor IER3

Publicationsfor IER3

Search for IER3

Genome Databases showing IER3

Other Databases showing IER3

Specialized Databases showing IER3

Licensable Technologiesfor IER3

Servicesfor IER3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for IER3

Summaries
for IER3

Genomic Location
for IER3

Proteins
for IER3

Protein Domains/
Families
for IER3

Gene Function
for IER3

Pathways & Interactions
for IER3

Drugs & Compounds
for IER3

Transcripts
for IER3

Expression
for IER3

Orthologs
for IER3

Paralogs
for IER3

SNPs/Variants
for IER3

Disorders & Mutations
for IER3

Medical News
for IER3

Publications
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