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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IDI2 Gene

protein-coding   GIFtS: 58
GCID: GC10M001064

Isopentenyl-Diphosphate Delta Isomerase 2

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Isopentenyl-Diphosphate Delta Isomerase 21 2     Diphosphate Dimethylallyl Diphosphate Isomerase 22
Isopentenyl Pyrophosphate Isomerase 22 3     Isopentenyl-Diphosphate Delta-Isomerase 22
IPPI22 3     EC 5.3.3.23
IPP Isomerase 22 3     

External Ids:    HGNC: 234871   Entrez Gene: 917342   Ensembl: ENSG000001483777   OMIM: 6153895   UniProtKB: Q9BXS13   

Export aliases for IDI2 gene to outside databases

Previous GC identifers: GC10M001035 GC10M001018 GC10M001054 GC10M001004


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IDI2 Gene: 
IDI2 (isopentenyl-diphosphate delta isomerase 2) is a protein-coding gene. Diseases associated with IDI2 include lateral sclerosis, and amyotrophic lateral sclerosis, and among its related super-pathways are superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) and Metabolic pathways. GO annotations related to this gene include hydrolase activity and isopentenyl-diphosphate delta-isomerase activity. An important paralog of this gene is IDI1.

UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly
electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_008705.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IDI2 gene promoter:
         Max1   STAT1   STAT1beta   STAT5A   CUTL1   STAT1alpha   PPAR-alpha   NF-kappaB1   ATF6   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): IDI2 promoter sequence
   Search SABiosciences Chromatin IP Primers for IDI2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IDI2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p15.3   Ensembl cytogenetic band:  10p15.3   HGNC cytogenetic band: 10p15.3

IDI2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IDI2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M001064:  view genomic region     (about GC identifiers)

Start:
1,064,847 bp from pter      End:
1,071,799 bp from pter
Size:
6,953 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1 (See protein sequence)
Recommended Name: Isopentenyl-diphosphate Delta-isomerase 2  
Size: 227 amino acids; 26753 Da
Cofactor: Binds 1 magnesium ion per subunit (By similarity)
Subcellular location: Peroxisome
1 PDB 3D structure from and Proteopedia for IDI2:
2PNY (3D)    

Explore the universe of human proteins at neXtProt for IDI2: NX_Q9BXS1

Explore proteomics data for IDI2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BXS1

  • IDI2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IDI2 Protein Expression
    REFSEQ proteins: NP_150286.1  
    ENSEMBL proteins: 
     ENSP00000277517  
    Reactome Protein details: Q9BXS1
    Human Recombinant Protein Products for IDI2: 
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    Novus Biologicals IDI2 Proteins
    Novus Biologicals IDI2 Lysates
    Sino Biological Recombinant Protein for IDI2
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for IDI2
    Cloud-Clone Corp. Proteins for IDI2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome IDA17202134
    GO:0005829cytosol TAS--

    IDI2 for ontologies           About GeneDecksing



    IDI2 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for IDI2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: isopentenyl-diphosphate Δ-isomerase 2 
    Lanosterol biosynthesis pathway

    3 InterPro protein domains:
     IPR015797 NUDIX_hydrolase_dom-like
     IPR011876 IsopentenylPP_isomerase_typ1
     IPR000086 NUDIX_hydrolase_dom

    Graphical View of Domain Structure for InterPro Entry Q9BXS1

    ProtoNet protein and cluster: Q9BXS1

    2 Blocks protein domains:
    IPB000086 NUDIX hydrolase
    IPB002667 Isopentenyl-diphosphate delta-isomerase


    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Similarity: Belongs to the IPP isomerase type 1 family
    Similarity: Contains 1 nudix hydrolase domain


    IDI2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IDI2_HUMAN, Q9BXS1
    Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly
    electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
    Catalytic activity: Isopentenyl diphosphate = dimethylallyl diphosphate

         Enzyme Number (IUBMB): EC 5.3.3.21

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004452isopentenyl-diphosphate delta-isomerase activity IDA17202134
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    IDI2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for IDI2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IDI2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IDI2 
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    miRNA
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    Inhib. RNA
    Products:
        
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                         Customized lentivirus expression plasmids for stable overexpression of IDI2 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for IDI2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
    superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)0.85
    Terpenoid backbone biosynthesis0.55
    mevalonate pathway I0.85
    trans, trans-farnesyl diphosphate biosynthesis0.31
    2Metabolism
    Metabolism0.40
    Metabolism of lipids and lipoproteins0.34
    Metabolic pathways0.40
    3cholesterol biosynthesis III (via desmosterol)
    Cholesterol biosynthesis0.85
    superpathway of cholesterol biosynthesis0.85

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4 BioSystems Pathways for IDI2
        superpathway of cholesterol biosynthesis
    trans, trans-farnesyl diphosphate biosynthesis
    mevalonate pathway I
    superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)


    3        Reactome Pathways for IDI2
        Metabolism
    Cholesterol biosynthesis
    Metabolism of lipids and lipoproteins


    2         Kegg Pathways  (Kegg details for IDI2):
        Terpenoid backbone biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Pathway: Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from
    isopentenyl diphosphate: step 1/1


    IDI2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IDI2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for IDI2 (Q9BXS13 ENSP000002775174) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCL6P411823, ENSP000002320144I2D: score=2 STRING: ENSP00000232014
    FDPSENSP000003490784STRING: ENSP00000349078
    GGPS1ENSP000002828414STRING: ENSP00000282841
    IDI1ENSP000003707484STRING: ENSP00000370748
    MVDENSP000003010124STRING: ENSP00000301012
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006695cholesterol biosynthetic process TAS--
    GO:0008299isoprenoid biosynthetic process IDA17202134
    GO:0044281small molecule metabolic process TAS--
    GO:0046490isopentenyl diphosphate metabolic process IDA17202134
    GO:0050992dimethylallyl diphosphate biosynthetic process IEA--

    IDI2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IDI2

    3 HMDB Compounds for IDI2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Dimethylallylpyrophosphate1,1-Dimethyl-4-phenylpiperazinium iodide (see all 24)358-72-5--
    Isopentenyl pyrophosphate3-Methyl-3-butenyl pyrophosphate (see all 13)358-71-4--
    MagnesiumMagnesium (see all 2)7439-95-4--

    Search CenterWatch for drugs/clinical trials and news about IDI2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IDI2 gene: 
    NM_033261.2  

    Unigene Clusters for IDI2:

    Isopentenyl-diphosphate delta isomerase 2
    Hs.9270  [show with all ESTs], Hs.591325  [show with all ESTs]
    Unigene Representative Sequences: BC040651, BC017778
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000277517(uc001ifv.1)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidIDI2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IDI2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IDI2
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    OriGene clones in human, mouse for IDI2 (see all 6)
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    GenScript Custom all cDNA clones Services for IDI2
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IDI2

    Additional mRNA sequence: 

    AF271725.1 AK056950.1 BC017778.1 

    5 DOTS entries:

    DT.100751051  DT.110855  DT.95272315  DT.100702798  DT.92033109 

    17 AceView cDNA sequences:

    AK056950 NM_033261 AA197141 BF670552 BM751331 F00114 BG183145 BG184320 
    BX500308 BC017778 AF271725 AA197116 BG217172 CA313071 BG187975 F00607 
    BG211295 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IDI2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACACAATGT
    IDI2 Expression
    About this image


    See IDI2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IDI2

    SOURCE GeneReport for Unigene clusters: Hs.9270 Hs.591325

    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Tissue specificity: Detected in skeletal muscle

        SABiosciences Expression via Pathway-Focused PCR Array including IDI2: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDI2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for IDI2 gene from 7/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Idi25 isopentenyl-diphosphate delta isomerase 2   --   13 (3.63 cM) 8952863 
    chicken
    (Gallus gallus)
    Aves --
    --
    59(a)
    1 → many
    2(10368356-10373419)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    58(a)
    1 → many
    6(8112544-8117708)
    zebrafish
    (Danio rerio)
    Actinopterygii idi16
    isopentenyl-diphosphate delta isomerase 1
    48(a)
    1 → many
    24(3547093-3554823)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG59193 isopentenyl-diphosphate
    delta-isomerase
    42(a)   93D2   --
    worm
    (Caenorhabditis elegans)
    Secernentea idi-16
    Protein IDI-1
    31(a)
    1 → many
    III(8091706-8093043)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes IDI16
    Isopentenyl diphosphate:dimethylallyl diphosphate ...
    32(a)
    1 → many
    XVI(327864-328730)


    ENSEMBL Gene Tree for IDI2 (if available)
    TreeFam Gene Tree for IDI2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IDI2 gene
    IDI12  
    1 SIMAP similar gene for IDI2 using alignment to 1 protein entry:     IDI2_HUMAN:
    IDI1

    IDI2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/104 SNPs in IDI2 are shown (see all 104)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs122517491,2
    C,F,H--1064382(+) aaaTAC/TCAGGT 1 -- ds50015Minor allele frequency- T:0.02NS NA 486
    rs1447165121,2
    C--1064411(+) TCTCCA/GTATTA 1 -- ds50010--------
    rs558610991,2
    C--1064449(+) TTTGTA/GTTAAA 1 -- ds50010--------
    rs1481141121,2
    --1064450(+) TTGTGC/TTAAAC 1 -- ds50010--------
    rs1429140311,2
    --1064463(+) CAACAA/GTATGG 1 -- ds50010--------
    rs560498011,2
    C--1064464(+) AACAGC/TATG 1 -- ds50010--------
    rs1834052041,2
    --1064525(+) AGGCGA/GATCAC 1 -- ds50010--------
    rs1891200431,2
    C--1064575(+) AACCCC/TGTCTC 1 -- ds50010--------
    rs1917970791,2
    C--1064576(+) ACCCCA/GTCTCT 1 -- ds50010--------
    rs73582161,2
    C--1064616(+) ggtggC/Tgggcg 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for IDI2 (1064847 - 1071799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for IDI2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2660097CNV Deletion23128226
    dgv589n71CNV Loss21882294


    Human Gene Mutation Database (HGMD): IDI2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing IDI2
    DNA2.0 Custom Variant and Variant Library Synthesis for IDI2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615389    OMIM disorders: --

    4 diseases for IDI2:    About MalaCards
    lateral sclerosis    amyotrophic lateral sclerosis    tuberculosis    alzheimer's disease


    IDI2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): IDI2
    Human Genome Epidemiology (HuGE) Navigator: IDI2 (1 document)

    Export disorders for IDI2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IDI2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with IDI2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IDI2, a second isopentenyl diphosphate isomerase in mammals. (PubMed id 17202134)1, 2, 9 Clizbe D.B.... Krisans S.K. (2007)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Segmental copy-number gain within the region of isope ntenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis. (PubMed id 20955688)1 Kato T....Matsubara K. (2010)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    9. Analysis of BCL6-interacting proteins by tandem mass spectrometry. (PubMed id 16147992)1 Miles R.R....Elenitoba-Johnson K.S. (2005)
    10. Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication. (PubMed id 14629038)1 Breitling R....Krisans S.K. (2003)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91734 HGNC: 23487 AceView: IDI2 Ensembl:ENSG00000148377 euGenes: HUgn91734
    ECgene: IDI2 Kegg: 91734 H-InvDB: IDI2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IDI2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IDI2 gene:
    Search GeneIP for patents involving IDI2

    GeneCards and IP:
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