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IDI2 Gene

protein-coding   GIFtS: 58
GCID: GC10M001064

Isopentenyl-Diphosphate Delta Isomerase 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Isopentenyl-Diphosphate Delta Isomerase 21 2     Diphosphate Dimethylallyl Diphosphate Isomerase 22
IPPI22 3 5     Isopentenyl-Diphosphate Delta-Isomerase 22
Isopentenyl Pyrophosphate Isomerase 22 3     EC 5.3.3.23
IPP Isomerase 22 3     

External Ids:    HGNC: 234871   Entrez Gene: 917342   Ensembl: ENSG000001483777   OMIM: 6153895   UniProtKB: Q9BXS13   

Export aliases for IDI2 gene to outside databases

Previous GC identifers: GC10M001035 GC10M001018 GC10M001054 GC10M001004


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IDI2 Gene:
IDI2 (isopentenyl-diphosphate delta isomerase 2) is a protein-coding gene. Diseases associated with IDI2 include lateral sclerosis, and amyotrophic lateral sclerosis. GO annotations related to this gene include hydrolase activity and isopentenyl-diphosphate delta-isomerase activity. An important paralog of this gene is IDI1.

UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly
electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_008705.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the IDI2 gene promoter:
         Max1   STAT1   STAT1beta   STAT5A   CUTL1   STAT1alpha   PPAR-alpha   NF-kappaB1   ATF6   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): IDI2 promoter sequence
   Search Chromatin IP Primers for IDI2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IDI2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p15.3   Ensembl cytogenetic band:  10p15.3   HGNC cytogenetic band: 10p15.3

IDI2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IDI2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M001064:  view genomic region     (about GC identifiers)

Start:
1,064,847 bp from pter      End:
1,071,799 bp from pter
Size:
6,953 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1 (See protein sequence)
Recommended Name: Isopentenyl-diphosphate delta-isomerase 2  
Size: 227 amino acids; 26753 Da
Cofactor: Binds 1 magnesium ion per subunit (By similarity)
1 PDB 3D structure from and Proteopedia for IDI2:
2PNY (3D)    

Explore the universe of human proteins at neXtProt for IDI2: NX_Q9BXS1

Explore proteomics data for IDI2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys47
  • Modification sites at PhosphoSitePlus

  • See IDI2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_150286.1  
    ENSEMBL proteins: 
     ENSP00000277517  
    Reactome Protein details: Q9BXS1

    IDI2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for IDI2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: isopentenyl-diphosphate Delta-isomerase 2
    Lanosterol biosynthesis pathway

    3 InterPro protein domains:
     IPR015797 NUDIX_hydrolase_dom-like
     IPR011876 IsopentenylPP_isomerase_typ1
     IPR000086 NUDIX_hydrolase_dom

    Graphical View of Domain Structure for InterPro Entry Q9BXS1

    ProtoNet protein and cluster: Q9BXS1

    2 Blocks protein domains:
    IPB000086 NUDIX hydrolase
    IPB002667 Isopentenyl-diphosphate delta-isomerase


    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Similarity: Belongs to the IPP isomerase type 1 family
    Similarity: Contains 1 nudix hydrolase domain


    IDI2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IDI2_HUMAN, Q9BXS1
    Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly
    electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
    Catalytic activity: Isopentenyl diphosphate = dimethylallyl diphosphate

         Enzyme Number (IUBMB): EC 5.3.3.21

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004452isopentenyl-diphosphate delta-isomerase activity IDA17202134
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    IDI2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IDI2
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDI2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IDI2_HUMAN, Q9BXS1: Peroxisome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    peroxisome5
    cytosol4
    cytoskeleton1
    extracellular1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome IDA17202134
    GO:0005829cytosol TAS--

    IDI2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IDI2 About    
    See pathways by source

    SuperPathContained pathways About
    1superpathway of cholesterol biosynthesis
    superpathway of cholesterol biosynthesis0.85
    superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)0.00
    Cholesterol biosynthesis0.85
    mevalonate pathway I0.00
    Terpenoid backbone biosynthesis0.34
    trans, trans-farnesyl diphosphate biosynthesis0.00
    2Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4 BioSystems Pathways for IDI2
        mevalonate pathway I
    trans, trans-farnesyl diphosphate biosynthesis
    superpathway of cholesterol biosynthesis
    superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)


    1 Reactome Pathway for IDI2
        Cholesterol biosynthesis


    2 Kegg Pathways  (Kegg details for IDI2):
        Terpenoid backbone biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Pathway: Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from
    isopentenyl diphosphate: step 1/1


    IDI2 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including IDI2: 

              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for IDI2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for IDI2 (Q9BXS13 ENSP000002775174) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCL6P411823, ENSP000002320144I2D: score=2 STRING: ENSP00000232014
    FDPSENSP000003490784STRING: ENSP00000349078
    GGPS1ENSP000002828414STRING: ENSP00000282841
    IDI1ENSP000003707484STRING: ENSP00000370748
    MVDENSP000003010124STRING: ENSP00000301012
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006695cholesterol biosynthetic process TAS--
    GO:0008299isoprenoid biosynthetic process IDA17202134
    GO:0044281small molecule metabolic process TAS--
    GO:0046490isopentenyl diphosphate metabolic process IDA17202134
    GO:0050992dimethylallyl diphosphate biosynthetic process IEA--

    IDI2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IDI2

    3 HMDB Compounds for IDI2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Dimethylallylpyrophosphate1,1-Dimethyl-4-phenylpiperazinium iodide (see all 24)358-72-5--
    Isopentenyl pyrophosphate3-Methyl-3-butenyl pyrophosphate (see all 13)358-71-4--
    MagnesiumMagnesium (see all 2)7439-95-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IDI2 gene: 
    NM_033261.2  

    Unigene Clusters for IDI2:

    Isopentenyl-diphosphate delta isomerase 2
    Hs.9270  [show with all ESTs], Hs.591325  [show with all ESTs]
    Unigene Representative Sequences: BC040651, BC017778
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000277517(uc001ifv.1)

    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat IDI2

    Additional mRNA sequence: 

    AF271725.1 AK056950.1 BC017778.1 

    5 DOTS entries:

    DT.100751051  DT.110855  DT.95272315  DT.100702798  DT.92033109 

    17 AceView cDNA sequences:

    NM_033261 AK056950 BX500308 AA197141 F00114 BG183145 BF670552 BG184320 
    BM751331 BC017778 AA197116 AF271725 BG217172 CA313071 BG211295 F00607 
    BG187975 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IDI2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACACAATGT
    IDI2 Expression
    About this image

    IDI2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IDI2 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.9270 Hs.591325

    UniProtKB/Swiss-Prot: IDI2_HUMAN, Q9BXS1
    Tissue specificity: Detected in skeletal muscle

        Pathway & Disease-focused RT2 Profiler PCR Array including IDI2: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for IDI2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Idi25 isopentenyl-diphosphate delta isomerase 2   --   13 (3.63 cM) 8952863 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    59(a)
    1 → many
    2(10368356-10373419)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    58(a)
    1 → many
    6(8112544-8117708)
    zebrafish
    (Danio rerio)
    Actinopterygii idi16
    isopentenyl-diphosphate delta isomerase 1
    48(a)
    1 → many
    24(3547093-3554823) ENSDARG00000019976
    fruit fly
    (Drosophila melanogaster)
    Insecta CG59193 isopentenyl-diphosphate
    delta-isomerase
    42(a)   93D2   --
    worm
    (Caenorhabditis elegans)
    Secernentea idi-16
    Protein IDI-1 (idi-1) mRNA, complete cds
    31(a)
    1 → many
    III(8091708-8093043) WBGene00019460
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes IDI16
    Isopentenyl diphosphate:dimethylallyl diphosphate ...
    31(a)
    1 → many
    XVI(327864-328730) YPL117C


    ENSEMBL Gene Tree for IDI2 (if available)
    TreeFam Gene Tree for IDI2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IDI2 gene
    IDI12  
    1 SIMAP similar gene for IDI2 using alignment to 1 protein entry:     IDI2_HUMAN:
    IDI1

    IDI2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IDI2 (see all 104)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs122517491,2
    C,F,H--1064382(+) aaaTAC/TCAGGT 1 -- ds50015Minor allele frequency- T:0.02NS NA 486
    rs1447165121,2
    C--1064411(+) TCTCCA/GTATTA 1 -- ds50010--------
    rs558610991,2
    C--1064449(+) TTTGTA/GTTAAA 1 -- ds50010--------
    rs1481141121,2
    --1064450(+) TTGTGC/TTAAAC 1 -- ds50010--------
    rs1429140311,2
    --1064463(+) CAACAA/GTATGG 1 -- ds50010--------
    rs560498011,2
    C--1064464(+) AACAGC/TATG 1 -- ds50010--------
    rs1834052041,2
    --1064525(+) AGGCGA/GATCAC 1 -- ds50010--------
    rs1891200431,2
    C--1064575(+) AACCCC/TGTCTC 1 -- ds50010--------
    rs1917970791,2
    C--1064576(+) ACCCCA/GTCTCT 1 -- ds50010--------
    rs73582161,2
    C--1064616(+) ggtggC/Tgggcg 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for IDI2 (1064847 - 1071799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for IDI2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660097CNV Deletion23128226
    dgv589n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): IDI2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IDI2
    DNA2.0 Custom Variant and Variant Library Synthesis for IDI2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615389    OMIM disorders: --

    4 diseases for IDI2:    
    About MalaCards
    lateral sclerosis    amyotrophic lateral sclerosis    tuberculosis    alzheimer's disease


    IDI2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): IDI2
    Human Genome Epidemiology (HuGE) Navigator: IDI2 (1 document)

    Export disorders for IDI2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IDI2 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with IDI2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IDI2, a second isopentenyl diphosphate isomerase in mammals. (PubMed id 17202134)1, 2, 9 Clizbe D.B.... Krisans S.K. (J. Biol. Chem. 2007)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis. (PubMed id 20955688)1 Kato T....Matsubara K. (Biochem. Biophys. Res. Commun. 2010)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Analysis of BCL6-interacting proteins by tandem mass spectrometry. (PubMed id 16147992)1 Miles R.R....Elenitoba-Johnson K.S. (amp 2005)
    10. Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication. (PubMed id 14629038)1 Breitling R....Krisans S.K. (J. Mol. Evol. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 91734 HGNC: 23487 AceView: IDI2 Ensembl:ENSG00000148377 euGenes: HUgn91734
    ECgene: IDI2 Kegg: 91734 H-InvDB: IDI2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IDI2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IDI2 gene:
    Search GeneIP for patents involving IDI2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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