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IDI1 Gene

protein-coding GIFtS: 57

GC10M001075

isopentenyl-diphosphate delta isomerase 1
(Previous name: isopentenyl-diphosphate delta isomerase )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 5.3.3.2 ^³
IPP1 ^²
IPPI1 ^², ³
OTTHUMP00000018951 ^²

Descriptions
IPP isomerase ^²
IPP isomerase 1 ^³
Isopentenyl pyrophosphate isomerase 1 ^², ³
isopentenyl diphosphate dimethylallyl diphosphate isomerase 1 ^²
isopentenyl-diphosphate delta isomerase ^¹, ²
isopentenyl-diphosphate delta isomerase 1 ^²

External Ids
HGNC: 5387¹
Entrez Gene: 3422²
UniProtKB: Q13907³
Ensembl: ENSG00000067064⁷

Search outside databases for aliases for IDI1 gene

Previous GC identifers: GC10M001056 GC10M001039

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for IDI1:

IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl

diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are

the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate

and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as

Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase

activity. [provided by RefSeq]

UniProtKB/Swiss-Prot: IDI1_HUMAN, Q13907

Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to

its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the IDI1 gene

Entrez Gene cytogenetic band: 10p15.3 Ensembl cytogenetic band: 10p15.3 HGNC cytogenetic band: 10p15.3

IDI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M001075: (about GC identifiers)

Start:	1,075,963 bp from pter
End:	1,085,061 bp from pter
Size:	9,099 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000010.9 NT_077567.3

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: IDI1_HUMAN, Q13907 (See protein sequence)

Recommended Name: Isopentenyl-diphosphate Delta-isomerase 1

Size: 227 amino acids; 26319 Da

Cofactor: Binds 1 magnesium ion per subunit

Subunit: Monomer

Subcellular location: Peroxisome

PDB structures from and Proteopedia :

2DHO (3D)

2I6K (3D)

2ICJ (3D)

2ICK (3D)

Secondary accessions: Q32Q13 Q53GQ6 Q86U81 Q8WUX8 Q96IZ4 Q9BQ74

REFSEQ proteins: NP_004499.2

ENSEMBL proteins:

ENSP00000370748

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (IDI1)
	Human Recombinant Proteins from Abnova (IDI1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005777	peroxisome	TAS	8188698
GO:0005829	cytosol	EXP	8806705

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Antibodies for IDI1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for IDI1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (IDI1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (IDI1)
	Novus Biologicals Antibodies for IDI1

Assays for IDI1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q13907

ProtoNet protein and cluster: Q13907

2 Blocks protein families:

IPB000086 NUDIX hydrolase

IPB002667 Isopentenyl-diphosphate delta-isomerase

UniProtKB/Swiss-Prot: IDI1_HUMAN, Q13907

Similarity: Belongs to the IPP isomerase type 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IDI1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IDI1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004508

Applied Biosystems Silencer® siRNAs for IDI1

Sigma-Aldrich siRNA and siRNA Panels for IDI1

Sigma-Aldrich shRNA for IDI1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for IDI1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004508
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004508
untagged cDNA clones in CMV expression vector (see all 3): NM_004508

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004508

UniProtKB/Swiss-Prot: IDI1_HUMAN, Q13907

Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to

its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

Catalytic activity: Isopentenyl diphosphate = dimethylallyl diphosphate

Enzyme Number (IUBMB): EC 5.3.3.2

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0004452	isopentenyl-diphosphate delta-isomerase activity	TAS	8020941
GO:0016787	hydrolase activity	IEA	--
GO:0016853	isomerase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for IDI1 (Your Favorite Gene powered by Ingenuity)

Biosynthesis of Steroids

GeneDecks IDI1 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: IDI1_HUMAN, Q13907

Pathway: Isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from

isopentenyl-PP: step 1/1

5/7 Interacting proteins for IDI1 (ENSP00000370748³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FDPS	ENSP00000357340³	STRING (score=.958)
IDI2	ENSP00000277517³	STRING (score=.904)
GGPS1	ENSP00000282841³	STRING (score=.899)
MVD	ENSP00000301012³	STRING (score=.899)
IPP	ENSP00000361090³	STRING (score=.898)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006695	cholesterol biosynthetic process	IEA	--
GO:0008299	isoprenoid biosynthetic process	TAS	8020941
GO:0016117	carotenoid biosynthetic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for IDI1
3 Novoseek chemical compound relationships for IDI1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
isopentenyl diphosphate	91.97	13	8806705 (2), 15381396 (2), 17250851 (2), 7908830 (1) (see all 7)
mevalonate	65.65	4	15206931 (1), 15381396 (1), 8739963 (1)
cholesterol	23.76	7	16020911 (1), 17478552 (1), 8739963 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IDI1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IDI1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004508

Sigma-Aldrich siRNA and siRNA Panels for IDI1

Sigma-Aldrich shRNA for IDI1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004508

REFSEQ mRNAs for IDI1 gene:

NM_004508.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004508

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004508
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004508
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_004508

Additional cDNA sequence:

AF271720.1 AK222875.1 AK303669.1 AK311110.1 BC005247.2 BC006999.2 BC019227.2 BC022418.2

BC025375.2 BC057827.1 BC107893.1 BT006761.1 BX537663.1 BX648472.1 CR590015.1 CR591790.1

CR596142.1 CR596871.1 CR597870.1 CR600177.1 CR602134.1 CR605332.1 CR613243.1 CR613434.1

CR614669.1 CR620656.1 CR624844.1 CR625468.1 CR625705.1 X17025.1

24/32 DOTS entries (see all 32 ):

DT.92462703 DT.453773 DT.99994257 DT.91911776 DT.100723192 DT.408305 DT.97838100 DT.100883548

DT.100883542 DT.95363710 DT.92462695 DT.121257216 DT.100000543 DT.100746628 DT.100883544 DT.100883550

DT.419678 DT.75101189 DT.100883547 DT.121257271 DT.97860180 DT.121257265 DT.121257275 DT.121257321

24/719 AceView cDNA sequences (see all 719 ):

AA340633 AW768267 BM854259 AV709829 AI925417 BQ225771 CR596142 AA479182

H72831 BM827224 AI002408 AA758485 BM977594 AL533574 AW105497 AI799723

AI189615 CA439039 CR624844 AL558036 CR625705 BQ776340 CR613434 BQ021407

highest scoring ESTs for IDI1:

AA018738 AL514404 AL695172 AL701325 AW362018 BC057827 BE891119 BF207964 BF210380 BF238776

Unigene Cluster for IDI1:

Isopentenyl-diphosphate delta isomerase 1

Hs.283652 [show with all ESTs]

Unigene Representative Sequence: BX537663

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for IDI1

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6a	·	6b
SP1:							-
SP2:							-		-		-
SP3:									-		-
SP4:

About this scheme

ECgene alternative splicing isoforms for IDI1

1 Ensembl transcript including schematic representation:

ENST00000381344

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

IDI1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IDI1

¹ / ² / ³

8 probe-sets matching IDI1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36985_at²^{, 3}	U95-A	1	1.00	1.00	0.97	1.03	X17025	0.80	1.00	0.91	1
83019_at²^{, 3}	U95-E	1	1.00	1.00	0.53	0.97	AI632279	0.60	1.00	0.82	1
204615_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004508	0.60	1.00	0.82	1
208881_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC005247	0.60	1.00	0.82	1
242065_x_at²^{, 3}	U133-B	1	0.64	1.00	--	--	BG477984	0.40	1.00	0.76	1
204615_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
208881_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
242065_x_at²	U133Plus2	1	0.64	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.283652
Expression variation in blood from EXPOLDB for IDI1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IDI1 gene from 5/19 species (see all 19 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	IDI1¹	--	isopentenyl-diphosphate delta isomerase 1	98.74(n) 98.58(a)	450263 XM_507622.2 XP_507622.2
cow (Bos taurus)	IDI1¹	--	isopentenyl-diphosphate delta isomerase 1	77(n) 76.41(a)	514293 NM_001075659.1 NP_001069127.1
rat (Rattus norvegicus)	Idi1¹	--	isopentenyl-diphosphate delta isomerase 1	84.14(n) 86.34(a)	89784 NM_053539.1 NP_445991.1
mouse (Mus musculus)	Idi1^{1, 5}	13⁵	isopentenyl-diphosphate delta isomerase^{1, 5}	85.02(n)¹ 86.78(a)¹	319554¹ NM_177960.3¹ NP_808875.1¹ AA716963⁵ AK029302⁵ (see all 13)
chicken (Gallus gallus)	IDI1¹	--	isopentenyl-diphosphate delta isomerase 1	69.88(n) 72.5(a)	420459 XM_418561.2 XP_418561.2

About this table Species with no ortholog for IDI1

ENSEMBL Gene Tree for IDI1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for IDI1 gene

IDI2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/66 NCBI SNPs in IDI1 are shown (see all 66 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 54)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs4880758^1,2	A,C,F,H	1075572(+)	`CCTTAC/GATTTT`	1	--	ng5¹		12	EU EA WA NA	1046
--	rs1285^1,2	A,C,F,H	1076116(+)	`ATACAC/TATTCC`	1	--	ut3¹ ese³		5	MN EU EA WA	596
--	rs11556792^1,2	H	1079968(-)	`GAAGAA/TTTGTC`	1	N/I	mis¹		4	EU EA WA	404
	rs11250238^1,2	A,C,F,H	1079616(+)	`GCACAC/TGCTTC`	1	--	int¹		8	EU EA WA	838
	rs1135416^1,2	A,C,F,H	1081308(-)	`ATTATA/TATTCA`	1	--	int¹		4	EU EA WA	408
	rs7075141^1,2	A,C,F,H	1081195(+)	`TATCTA/GTATCC`	1	--	int¹		21	EU EA WA NS NA	1512
--	rs7072554^1,2	C,F,H	1080988(+)	`CCATCC/TGTTTA`	1	--	int¹		4	EU EA WA	418
	rs12768746^1,2	C,F,H	1077551(+)	`ATAGTT/CTTAGG`	1	--	int¹		15	EU EA WA NA	1342
	rs7075188^1,2	C,F,H	1078746(+)	`CAAAGT/GAGGTC`	1	--	int¹		12	EU EA WA	1254
	rs7074880^1,2	F,H	1078565(+)	`AGAGCT/CGGTTA`	1	--	int¹		4	EU EA WA	420

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HapMap Linkage Disequilibrium images for IDI1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604055

1 PharmGKB disease relationship for IDI1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872 12730115

About this table

Human Genome Epidemiology Navigator: IDI1 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/26 PubMed articles for IDI1 gene (see all 26 ):

A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase. (PubMed id 8020941)^{2, 3, 4} Xuan J.W.... Denhardt D.T. (1994)
Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. (PubMed id 8806705)^{1, 3, 4} Hahn F.M.... Poulter C.D. (1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis. (PubMed id 17250851)^{1, 4} Zheng W.... Rao Z. (2007)
Copper induces the expression of cholesterogenic genes in human macrophages. (PubMed id 12860252)^{1, 3} Svensson P.A....Carlsson B. (2003)
Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)³ Lu Y....Boer J.M. (2008)
Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. (PubMed id 16806233)³ Ma J....Liew C.C. (2007)
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. (PubMed id 12730115)⁷ Ross M.E....Downing J.R. (2003)
Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication. (PubMed id 14629038)³ Breitling R....Krisans S.K. (2003)
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. (PubMed id 12086872)⁷ Yeoh E.J....Downing J.R. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3422	HGNC: 5387	AceView: IDI1	Ensembl:ENSG00000067064	euGenes: HUgn3422
ECgene: IDI1	H-InvDB: IDI1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for IDI1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for IDI1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for IDI1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IDI1		Antibodies for IDI1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for IDI1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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IDI1 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for IDI1

Summaries
for IDI1

Genomic Location
for IDI1

Proteins
for IDI1

Protein Domains/
Families
for IDI1

Gene Function
for IDI1

Pathways & Interactions
for IDI1

Drugs & Compounds
for IDI1

Transcripts
for IDI1

Expression
for IDI1

Orthologs
for IDI1

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SNPs/Variants
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Disorders & Mutations
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Medical News
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Search for IDI1

Genome Databases showing IDI1

Other Databases showing IDI1

Specialized Databases showing IDI1

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for IDI1

Services
for IDI1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IDI1 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor IDI1

Summariesfor IDI1

Genomic Locationfor IDI1

Proteinsfor IDI1

Protein Domains/Familiesfor IDI1

Gene Functionfor IDI1

Pathways & Interactionsfor IDI1

Drugs & Compoundsfor IDI1

Transcriptsfor IDI1

Expression for IDI1

Orthologsfor IDI1

Paralogsfor IDI1

SNPs/Variantsfor IDI1

Disorders & Mutationsfor IDI1

Medical Newsfor IDI1

Publicationsfor IDI1

Search for IDI1

Genome Databases showing IDI1

Other Databases showing IDI1

Specialized Databases showing IDI1

Licensable Technologiesfor IDI1

Servicesfor IDI1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for IDI1

Summaries
for IDI1

Genomic Location
for IDI1

Proteins
for IDI1

Protein Domains/
Families
for IDI1

Gene Function
for IDI1

Pathways & Interactions
for IDI1

Drugs & Compounds
for IDI1

Transcripts
for IDI1

Expression
for IDI1

Orthologs
for IDI1

Paralogs
for IDI1

SNPs/Variants
for IDI1

Disorders & Mutations
for IDI1

Medical News
for IDI1

Publications
for IDI1

Licensable Technologies
for IDI1

Services
for IDI1