V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

IDH3B Gene

protein-coding GIFtS: 60

GC20M002587

isocitrate dehydrogenase 3 (NAD+) beta
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 1.1.1.41 ^³
FLJ11043 ^²
H-IDHB ^²
MGC903 ^²
OTTHUMP00000030023 ^²
OTTHUMP00000030024 ^²
RP46 ^², ⁵

Descriptions
Isocitric dehydrogenase ^², ³
NAD(+)-specific ICDH ^³
NAD+-specific ICDH ^²
NAD+-specific isocitrate dehydrogenase b subunit ^²
NAD+-specific isocitrate dehydrogenase beta ^²
isocitrate dehydrogenase 3 (NAD+) beta ^²
isocitrate dehydrogenase 3, beta subunit ^²
isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit ^²

External Ids
HGNC: 5385¹
Entrez Gene: 3420²
UniProtKB: O43837³
Ensembl: ENSG00000101365⁷

Search outside databases for aliases for IDH3B gene

Previous GC identifers: GC20M002627 GC20M002634

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for IDH3B:

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.

These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron

acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three

NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two

NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other

predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically

regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer

that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein

encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate

dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have

been described for this gene. [provided by RefSeq]

Gene Wiki entry for IDH3B

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the IDH3B gene

Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC chromosome: 20

IDH3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M002587: (about GC identifiers)

Start:	2,587,041 bp from pter
End:	2,592,843 bp from pter
Size:	5,803 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000020.9 NT_011387.8

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837 (See protein sequence)

Recommended Name: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor

Size: 385 amino acids; 42184 Da

Cofactor: Binds 1 magnesium or manganese ion per subunit (By similarity)

Subunit: Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1 (By

similarity)

Subcellular location: Mitochondrion

Secondary accessions: O95106 Q5JXS8 Q9NQ06 Q9NQ07 Q9UEX0 Q9UG99

Alternative splicing: 2 isoforms: O43837-1 O43837-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_008830.2 NP_777280.1 NP_777281.1

ENSEMBL proteins:

ENSP00000343215 ENSP00000370223 ENSP00000370232

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (IDH3B)
	Human Recombinant Proteins from Abnova (IDH3B)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	TAS	10601238
GO:0005759	mitochondrial matrix	EXP	14555658

About this table

Antibodies for IDH3B:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for IDH3B
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (IDH3B), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (IDH3B)
	Novus Biologicals Antibody for IDH3B

Assays for IDH3B:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O43837

ProtoNet protein and cluster: O43837

1 Blocks protein family: IPB001804 Isocitrate/isopropylmalate dehydrogenase

UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837

Similarity: Belongs to the isocitrate and isopropylmalate dehydrogenases family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IDH3B)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IDH3B)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_006899

Applied Biosystems Silencer® siRNAs for IDH3B

Sigma-Aldrich siRNA for IDH3B

Sigma-Aldrich shRNA for IDH3B

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for IDH3B
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_006899
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_006899
untagged cDNA clones in CMV expression vector (see all 3): NM_006899

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006899

UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837

Catalytic activity: Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH

Enzyme Number (IUBMB): EC 1.1.1.41

Genatlas biochemistry entry for IDH3B:

isocitrate dehydrogenase 3,beta subunit,NADH dependent,mitochondrial matrix,third step of citric

acid cycle

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0004449	isocitrate dehydrogenase (NAD+) activity	TAS	10601238
GO:0009055	electron carrier activity	TAS	10601238
GO:0016491	oxidoreductase activity	IEA	--
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for IDH3B (Your Favorite Gene powered by Ingenuity)

Inositol Metabolism
Citrate Cycle

GeneDecks IDH3B for the pathways selected above

About GeneDecksing

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006099	tricarboxylic acid cycle	IEA	--
GO:0006102	isocitrate metabolic process	TAS	10601238
GO:0055114	oxidation reduction	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for IDH3B

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IDH3B)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IDH3B)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_006899

Sigma-Aldrich siRNA for IDH3B

Sigma-Aldrich shRNA for IDH3B

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006899 NM_174855 NM_174856

REFSEQ mRNAs for IDH3B gene (3 alternative transcripts):

NM_006899.2 NM_174855.1 NM_174856.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006899 NM_174855 NM_174856

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_006899
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_006899
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_006899

Additional cDNA sequence:

AK001905.1 AK300485.1 AK309488.1 AK315641.1 AL050094.1 BC001960.1 BC019037.2 BX647393.1

CR611698.1 CR614771.1 CR615180.1 CR615874.1 CR616056.1 CR618774.1 U87972.1

24/28 DOTS entries (see all 28 ):

DT.100806069 DT.40109134 DT.100877702 DT.95285118 DT.95370149 DT.449871 DT.92452736 DT.100877701

DT.97860645 DT.120797850 DT.120797673 DT.95144728 DT.120797750 DT.92452735 DT.120797617 DT.120797702

DT.120797834 DT.95187824 DT.120797848 DT.100877708 DT.120797829 DT.95370145 DT.120797638 DT.120797678

24/615 AceView cDNA sequences (see all 615 ):

BM837721 BU527242 CD514264 BM767626 AA812115 BU183474 BU687877 BM787861

AA775794 CB144089 CB138037 AI609203 BQ672338 CB158264 BU850158 BU931843

AA746315 AI890694 BG681653 AA554369 BQ929307 BM561496 BQ229720 BQ069660

highest scoring ESTs for IDH3B:

AA306645 AA323082 AA522698 AK001905 AL036756 AU099626 AU117859 AU143386 AV696918 AW402589

Unigene Cluster for IDH3B:

Isocitrate dehydrogenase 3 (NAD+) beta

Hs.436405 [show with all ESTs]

Unigene Representative Sequence: NM_174856

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for IDH3B (see all 13 )

ExUns:	1a	·	1b	^	2a	·	2b	^	3a	·	3b	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	·	9c	^	10a	·	10b	^	11	^	12a	·	12b	^
SP1:					-																						-																-
SP2:					-																						-																-						-		-
SP3:					-																																						-
SP4:					-																						-		-		-		-
SP5:					-						-		-														-

ExUns:	13a	·	13b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for IDH3B

3 Ensembl transcripts including schematic representations:

ENST00000341825 ENST00000380843 ENST00000380851

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

IDH3B expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IDH3B

¹ / ² / ³

9 probe-sets matching IDH3B gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40110_at²^{, 3}	U95-A	1	1.00	1.00	0.02	0.80	U49283	0.80	1.00	0.91	1
40111_g_at²^{, 3}	U95-A	1	1.00	1.00	0.89	1.11	U49283	0.80	1.00	0.91	1
40112_at²^{, 3}	U95-A	1	0.94	1.00	0.85	1.09	AA522698	0.80	1.00	0.91	1
210418_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF023265	0.60	1.00	0.82	1
210014_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF023266	0.60	1.00	0.82	1
201509_at²^{, 3}	U133-A	1	0.91	1.00	--	--	NM_006899	0.60	1.00	0.82	1
210418_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
210014_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201509_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--

GeneDecks IDH3B for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AACCAAAAAA

SOURCE GeneReport for Unigene cluster: Hs.436405
Expression variation in blood from EXPOLDB for IDH3B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IDH3B gene from 5/21 species (see all 21 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	IDH3B¹	--	isocitrate dehydrogenase 3 (NAD+) beta	92.01(n) 96.35(a)	477177 XM_534367.2 XP_534367.2
chimpanzee (Pan troglodytes)	IDH3B¹	--	isocitrate dehydrogenase 3 (NAD+) beta	99.83(n) 99.74(a)	458048 XM_001157460.1 XP_001157460.1
cow (Bos taurus)	IDH3B¹	--	isocitrate dehydrogenase 3 (NAD+) beta	92.19(n) 94.27(a)	613338 XM_864062.2 XP_869155.1
rat (Rattus norvegicus)	Idh3B¹	--	isocitrate dehydrogenase 3 (NAD+) beta	90.02(n) 94.27(a)	94173 NM_053581.1 NP_446033.1
mouse (Mus musculus)	Idh3b^{1, 5}	2⁵	isocitrate dehydrogenase 3 (NAD+) beta^{1, 5}	89.3(n)¹ 93.99(a)¹	170718¹ NM_130884.2¹ NP_570954.1¹ AI324856⁵ AI838061⁵ (see all 15)

About this table Species with no ortholog for IDH3B

ENSEMBL Gene Tree for IDH3B

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for IDH3B gene

IDH3G² IDH3A²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/69 NCBI SNPs in IDH3B are shown (see all 69 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 27)

AB	SNP ID	Valid	Chr 20 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2422823^1,2	A,C,H	2594333(+)	`ATTCCC/AAGTGC`	3	--	ng3¹ tfbs³		4		EU EA WA	388
--	rs2235954^1,2	A,C,F	2592975(-)	`GCAAGA/GAAAAG`	3	--	ng3¹ trp³		3		EA MN	2754
	rs2073192^1,2	C,F,H	2592996(-)	`CATCCC/TATGAC`	3	--	ng3¹		10		MN EA EU WA	2084
--	rs6138735^1,2	A,C	2593199(+)	`CAGTAC/GTCACT`	3	--	ng3¹		0	--	--	--	--
--	rs2073197^1,2	C,F	2593077(-)	`TTTCCC/TCCTAA`	3	--	ng3¹ trp³		1		EA	1502
--	rs6132899^1,2	A,C	2593262(+)	`GTGTCA/GGGTTT`	3	--	ng3¹ tfbs³		0	--	--	--	--
--	rs2422822^1,2	A,C	2593702(+)	`CAATTA/CCAGTC`	3	--	ng3¹ tfbs³		0	--	--	--	--
--	rs11542741^1,2	H	2589376(-)	`GAGCAG/TACAGA`	3	Q/H	mis¹ ut5¹ ese³		4		EU EA WA	406
	rs2235955^1,2	A,C,F,O	2588102(-)	`ACTACC/TCTCTG`	3	--	int¹		5		EA NA	1860
	rs6107100^1,2	A,C,F,H	2592685(+)	`GTCAGA/CTTTGA`	3	--	int¹		7		EU EA NA	508

About this table

HapMap Linkage Disequilibrium images for IDH3B (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604526

UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837

Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is

a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by

retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells

followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness

and loss of midperipheral visual field. As their condition progresses, they lose their far

peripheral visual field and eventually central vision as well

Human Gene Mutation Database: IDH3B

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/15 PubMed articles for IDH3B gene (see all 15 ):

Assignment of mitochondrial NAD(+)-specific isocitrate dehydrogenase beta subunit gene (IDH3B) to human chromosome band 20p13 by in situ hybridization and radiation hybrid mapping. (PubMed id 10575215)^{1, 2, 3} Kim Y.O....Huh T.L. (1999)
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. (PubMed id 18806796)^{3, 4} Hartong D.T....Colman R.F. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{3, 4} Deloukas P....Rogers J. (2001)
Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase. (PubMed id 17432878)³ Bzymek K.P. and Colman R.F. (2007)
The full-ORF clone resource of the German cDNA Consortium. (PubMed id 17974005)⁴ Bechtel S....Schupp I. (2007)
Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase. (PubMed id 16737955)³ Soundar S....Colman R.F. (2006)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)³ Lim J....Zoghbi H.Y. (2006)
Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation. (PubMed id 15653693)³ Kil I.S. and Park J.W. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3420	HGNC: 5385	AceView: IDH3B	Ensembl:ENSG00000101365	euGenes: HUgn3420
ECgene: IDH3B	H-InvDB: IDH3B

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for IDH3B
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for IDH3B:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for IDH3B-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IDH3B		Antibodies for IDH3B
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for IDH3B		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (IDH3B)
	Antibodies (IDH3B)
	Chimera RNAi (IDH3B)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (IDH3B)
	Antibodies (IDH3B)

Search OriGene for IDH3B

Search Tocris compounds for IDH3B

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for IDH3B

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
IDH3B Gene at Home site.
Version 2.41.1
server4.xennexinc.com

IDH3B Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for IDH3B

Summaries
for IDH3B

Genomic Location
for IDH3B

Proteins
for IDH3B

Protein Domains/
Families
for IDH3B

Gene Function
for IDH3B

Pathways & Interactions
for IDH3B

Drugs & Compounds
for IDH3B

Transcripts
for IDH3B

Expression
for IDH3B

Orthologs
for IDH3B

Paralogs
for IDH3B

SNPs/Variants
for IDH3B

Disorders & Mutations
for IDH3B

Medical News
for IDH3B

Publications
for IDH3B

Search for IDH3B

Genome Databases showing IDH3B

Other Databases showing IDH3B

Specialized Databases showing IDH3B

Licensable Technologies
for IDH3B

Services
for IDH3B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IDH3B Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor IDH3B

Summariesfor IDH3B

Genomic Locationfor IDH3B

Proteinsfor IDH3B

Protein Domains/Familiesfor IDH3B

Gene Functionfor IDH3B

Pathways & Interactionsfor IDH3B

Drugs & Compoundsfor IDH3B

Transcriptsfor IDH3B

Expression for IDH3B

Orthologsfor IDH3B

Paralogsfor IDH3B

SNPs/Variantsfor IDH3B

Disorders & Mutationsfor IDH3B

Medical Newsfor IDH3B

Publicationsfor IDH3B

Search for IDH3B

Genome Databases showing IDH3B

Other Databases showing IDH3B

Specialized Databases showing IDH3B

Licensable Technologiesfor IDH3B

Servicesfor IDH3B

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for IDH3B

Summaries
for IDH3B

Genomic Location
for IDH3B

Proteins
for IDH3B

Protein Domains/
Families
for IDH3B

Gene Function
for IDH3B

Pathways & Interactions
for IDH3B

Drugs & Compounds
for IDH3B

Transcripts
for IDH3B

Expression
for IDH3B

Orthologs
for IDH3B

Paralogs
for IDH3B

SNPs/Variants
for IDH3B

Disorders & Mutations
for IDH3B

Medical News
for IDH3B

Publications
for IDH3B

Licensable Technologies
for IDH3B

Services
for IDH3B