IDH3B Gene
protein-coding GIFtS: 60
GCID: GC20M002639
|
|
isocitrate dehydrogenase 3 (NAD+) beta
| |
Aliases
for IDH3B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Isocitrate Dehydrogenase 3 (NAD+) Beta1 2 | | Isocitrate Dehydrogenase [NAD] Subunit Beta, Mitochondrial2 | | RP461 2 5 | | Isocitrate Dehydrogenase, NAD(+)-Specific, Mitochondrial, Beta Subunit2 | | Isocitric Dehydrogenase Subunit Beta2 3 | | NAD+-Specific ICDH2 | | NAD(+)-Specific ICDH Subunit Beta2 3 | | NAD+-Specific Isocitrate Dehydrogenase B Subunit2 | | EC 1.1.1.413 8 | | NAD+-Specific Isocitrate Dehydrogenase Beta2 | | H-IDHB2 | | EC 1.1.18 |
Export aliases for IDH3B gene to outside databasesPrevious GC identifers: GC20M002627 GC20M002634 GC20M002587 |
Summaries
for IDH3B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IDH3B:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belongto two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Fiveisocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to themitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the otherpredominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulatedrate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alphasubunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozymeof NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding differentisoforms have been described for this gene. (provided by RefSeq, Jul 2008)
Gene Wiki entry for IDH3B
|
Genomic Views
for IDH3B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IDH3B gene promoter:
GR GR-beta Pax-6 AREB6 HEN1 MZF-1 S8 ZID GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for IDH3B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IDH3B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13IDH3B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M002639: view genomic region
(about GC identifiers)
Start:
|
2,639,041 bp from pter |
End:
|
2,644,865 bp from pter |
Size:
|
5,825 bases |
Orientation:
|
minus strand |
|
Proteins
for IDH3B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837 (See
protein sequence)Recommended Name: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor Size: 385 amino acids; 42184 Da
Cofactor: Binds 1 magnesium or manganese ion per subunit (By similarity)
Subunit: Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1 (By similarity)
Subcellular location: Mitochondrion
Secondary accessions: B2RDR1 D3DVX2 D3DVX3 O95106 Q5JXS8 Q9NQ06 Q9NQ07 Q9NUZ0 Q9UEX0 Q9UG99Alternative splicing: 3 isoforms: O43837-1 O43837-2 O43837-3 Explore the universe of human proteins at neXtProt for IDH3B: NX_O43837
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43837
4/15 DME Specific Peptides for IDH3B (O43837) (see all 15)
IDH3B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001245313.1 NP_008830.2 NP_777280.1
ENSEMBL proteins: ENSP00000370232 ENSP00000370223 ENSP00000410058 Reactome Protein details: O43837
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
IDH3B for ontologies About GeneDecksing
IDH3B Antibody Products:
Assay Products for IDH3B: |
Protein
Domains /
Families
for IDH3B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IDH3B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43837ProtoNet protein and cluster: O43837 1 Blocks protein family: IPB001804 Isocitrate/isopropylmalate dehydrogenase
UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837Similarity: Belongs to the isocitrate and isopropylmalate dehydrogenases family |
Function
for IDH3B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837Catalytic activity: Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH Genatlas biochemistry entry for IDH3B:isocitrate dehydrogenase 3,beta subunit,NADH dependent,mitochondrial matrix,third step of citric acid cycle
Enzyme Numbers (IUBMB): EC 1.1.1.411 2 EC 1.1.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for IDH3B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3B |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
IDH3B for ontologies About GeneDecksing
|
Pathways & Interactions
for IDH3B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TCA Cycle | | | 2 | Metabolism | | | 3 | TCA cycle II (eukaryotic) | | | 4 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for IDH3B
4 
Reactome Pathways for IDH3B
2 
Kegg Pathways (Kegg details for IDH3B):
IDH3B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IDH3B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/47 Interacting proteins for IDH3B (O438372, 3 ENSP000003702234) via UniProtKB, MINT, STRING, and/or I2D (see all 47)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006099 | tricarboxylic acid cycle |
TAS | -- | | GO:0006102 | isocitrate metabolic process |
IEA | -- | | GO:0006103 | 2-oxoglutarate metabolic process |
IEA | -- | | GO:0006734 | NADH metabolic process |
IEA | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
IDH3B for ontologies About GeneDecksing
|
Drugs & Compounds
for IDH3B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IDH3B
7 HMDB Compounds for IDH3B About this table
1 DrugBank Compound for IDH3B About this table
Search CenterWatch for drugs/clinical trials and news about IDH3B
|
Transcripts
for IDH3B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IDH3B gene (4 alternative transcripts): NM_001258384.1 NM_006899.3 NM_174855.2 NM_174856.1 Unigene Cluster for IDH3B: Isocitrate dehydrogenase 3 (NAD+) beta Hs.436405 [show with all ESTs]Unigene Representative Sequence: BX64739313 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000466494 ENST00000492240 ENST00000469213 ENST00000488299 ENST00000474315
ENST00000380851(uc002wgq.3) ENST00000380843(uc002wgp.3) ENST00000477689
ENST00000466999 ENST00000479376 ENST00000462967 ENST00000491065(uc010zpz.1)
ENST00000435594(uc002wgr.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): IDH3B (NM_174855) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IDH3B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3B |
Additional cDNA sequence: AK300485.1 AK309488.1 AK315641.1 AL050094.1 BC001960.1 BC019037.2 BX647393.1 U87972.1 24/28 DOTS entries (see all 28): DT.40109134 DT.100806069 DT.100877702 DT.95285118 DT.95370149 DT.449871 DT.92452736 DT.100877701 DT.97860645 DT.120797850 DT.120797673 DT.95144728 DT.120797750 DT.92452735 DT.120797617 DT.120797702 DT.120797834 DT.95187824 DT.120797848 DT.100877708 DT.120797829 DT.95370145 DT.120797638 DT.120797678 24/615 AceView cDNA sequences (see all 615): AI372963 CD514264 BM753004 BU683689 AA284682 CD653489 CA449253 CN485078 BQ053873 BM451605 BU956783 F37091 BG939965 AI890694 CB138909 F29067 BM465164 BM510099 CB217069 BE790732 BM743955 BM768201 BM970717 BQ877366
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for IDH3B (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | - | | - | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 13a | · | 13b |
|---|
|
| SP1: | | | | | |
| SP2: | | | | | |
| SP3: | | | | | |
| SP4: | | | | | |
| SP5: | | | | |
ECgene alternative splicing isoforms for IDH3B
|
Expression
for IDH3B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IDH3B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCAAAAAA
About this image
See IDH3B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IDH3B
SOURCE GeneReport for Unigene cluster: Hs.436405
SABiosciences Expression via Pathway-Focused PCR Arrays including IDH3B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IDH3B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IDH3B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IDH3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IDH3B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3B |
Orthologs
for IDH3B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for IDH3B gene from 11/37 species (see all 37) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Idh3b1 , 5 |
isocitrate dehydrogenase 3 (NAD+) beta1, 5 |
89.38(n)1
93.99(a)1 |
|
2 (63.20 cM)5
1707181 NM_130884.41 NP_570954.11
1302793095 |
chicken
(Gallus gallus) |
Aves |
IDH3B1 |
isocitrate dehydrogenase 3 (NAD+) beta |
78.54(n)
85.22(a) |
|
426573 NM_001031387.1 NP_001026558.1 |
lizard
(Anolis carolinensis) |
Reptilia |
IDH3B6 |
-- |
83(a) |
1 ↔ 1 |
GL343574.1(183716-197022) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BX850675.12 |
-- |
80.35(n) |
|
BX850675.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.120462 |
Transcribed sequence with moderate similarity to protein more |
78.23(n) |
|
CA472002.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG64391 , 3 |
isocitrate dehydrogenase (NAD+)3
CG64391 |
60(a)
(best of 3)3
61.99(n)1
61.32(a)1 |
|
93F133
425861 NM_142743.21 NP_651000.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C37E2.13
idhb-11 |
isocitrate dehydrogenase3
Protein IDHB-11 |
60(a)
(best of 2)3
58.95(n)1
61.71(a)1 |
|
X(14206688-14208613)3
1815281 NM_077961.41 NP_510362.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
IDH11 |
Idh1p |
50.61(n)
46.2(a) |
|
855691 NP_014361.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
IDH21 |
Isocitrate dehydrogenase [NAD] regulatory subunit 2 |
56.94(n)
53.11(a) |
|
816218 NM_127267.2 NP_179304.1 |
rice
(Oryza sativa) |
Liliopsida |
Os04g04792001 |
hypothetical protein |
54.93(n)
51.4(a) |
|
4336169 NM_001059628.1 NP_001053093.1 |
ENSEMBL Gene Tree for IDH3B (if available)
TreeFam Gene Tree for IDH3B (if available) |
Paralogs
for IDH3B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IDH3B gene
- IDH3G2
2 SIMAP similar genes for IDH3B using alignment to 2 protein entries: IDH3B_HUMAN (see all proteins):IDH3G IDH3A
IDH3B for paralogs About GeneDecksing
|
Genomic Variants
for IDH3B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IDH3B (2639041 - 2644865 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IDH3B: --
Human Gene Mutation Database (HGMD): IDH3B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IDH3B |
|
Disorders
/ Diseases
for IDH3B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IDH3B for disorders About GeneDecksing
OMIM gene information: 604526
OMIM disorders: --
UniProtKB/Swiss-Prot: IDH3B_HUMAN, O43837
Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophybelonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundusexamination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patientstypically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they losetheir far peripheral visual field and eventually central vision as well
6  diseases for IDH3B: About MalaCardsretinitis pigmentosa-46 pigmentary retinopathy retinitis pigmentosa retinitis
blindness ataxia
Human Genome Epidemiology (HuGE) Navigator: IDH3B (1 document)
Export disorders for IDH3B gene to outside databases
|
Publications
for IDH3B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IDH3B gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with IDH3B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Assignment of mitochondrial NAD(+)-specific isocitrate dehydrogenase beta subunit gene (IDH3B) to human chromosome band 20p13 by in situ hybridization and radiation hybrid mapping. (PubMed id 10575215)1, 3, 9 Kim Y.O....Huh T.L. (1999)
- Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. (PubMed id 18806796)1, 2 Hartong D.T....Colman R.F. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Identification and functional characterization of a novel, tissue- specific NAD+-dependent isocitrate dehydrogenase beta subunit isoform. (PubMed id 10601238)1, 2 Kim Y.-O.... Huh T.-L. (1999)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for IDH3B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing IDH3B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing IDH3B gene
(According to HUGE)
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Specialized Databases showing IDH3B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for IDH3B | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for IDH3B gene:
Search GeneIP for patents involving IDH3B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for IDH3B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IDH3B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IDH3B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IDH3B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IDH3B | | OriGene 3'-UTR Clone for IDH3B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IDH3B | | OriGene Custom Protein Services for IDH3B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IDH3B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IDH3B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IDH3B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IDH3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IDH3B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IDH3B |
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| | | | Search Tocris compounds for IDH3B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3B |
|  |  |  | | | | Search ThermoFisher Antibodies for IDH3B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3B |
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