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ID3 Gene

protein-coding GIFtS: 65

GC01M023756

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
1R21 ^³
HEIR-1 ^¹, ², ³
OTTHUMP00000003263 ^²
bHLHb25 ^¹, ²

Descriptions
Helix-loop-helix protein HEIR-1 ^³
ID-like protein inhibitor HLH 1R21 ^³
Inhibitor of DNA binding 3 ^², ³
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein ^²

External Ids
HGNC: 5362¹
Entrez Gene: 3399²
UniProtKB: Q02535³
Ensembl: ENSG00000117318⁷

Search outside databases for aliases for ID3 gene

Previous GC identifers: GC01M023442 GC01M022955 GC01M023353 GC01M023629

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ID3:

Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and

inhibit transcription through formation of nonfunctional dimers that are incapable of binding to

DNA.[supplied by OMIM]

UniProtKB/Swiss-Prot: ID3_HUMAN, Q02535

Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able

to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the

binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit

other transcription factors

Gene Wiki entry for ID3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ID3 gene

Entrez Gene cytogenetic band: 1p36.13-p36.12 Ensembl cytogenetic band: 1p36.12 HGNC cytogenetic band: 1p36.13-p36.12

ID3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M023756: (about GC identifiers)

Start:	23,756,996 bp from pter
End:	23,758,909 bp from pter
Size:	1,914 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.9 NT_004610.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ID3_HUMAN, Q02535 (See protein sequence)

Recommended Name: DNA-binding protein inhibitor ID-3

Size: 119 amino acids; 12969 Da

Subunit: Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH

proteins

Subcellular location: Nucleus

Secondary accessions: O75641

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002158.3

ENSEMBL proteins:

ENSP00000363689

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ID3)
	Human Recombinant Proteins from Abnova (ID3)

OriGene Purified Recombinant Human Protein: ID3

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

About this table

Antibodies for ID3:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of ID3
	Sigma-Aldrich Antibodies for ID3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ID3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ID3)
	Novus Biologicals Antibodies for ID3

Assays for ID3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q02535

ProtoNet protein and cluster: Q02535

1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH

UniProtKB/Swiss-Prot: ID3_HUMAN, Q02535

Similarity: Contains 1 basic helix-loop-helix (bHLH) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ID3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ID3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002167

Applied Biosystems Silencer® siRNAs for ID3

Sigma-Aldrich siRNA for ID3

Sigma-Aldrich shRNA for ID3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ID3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002167
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002167
untagged cDNA clone in CMV expression vector: NM_002167

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002167

UniProtKB/Swiss-Prot: ID3_HUMAN, Q02535

Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able

to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the

binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit

other transcription factors

Induction: By phorbol 12-myristate 13-acetate (PMA)

Genatlas biochemistry entry for ID3:

inhibitor of DNA binding 3,mouse ld-3 related,expressed during early development and in adult

tissues,inhibing transcription factors of the basic helix loop helix family, required for

neurogenesis and angiogenesis

8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Id3):

	embryogenesis	growth/size	hematopoietic system	immune system
lethality-prenatal/perinatal	nervous system	tumorigenesis

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003714	transcription corepressor activity	TAS	8437843
GO:0008134	transcription factor binding	IEA	--
GO:0019904	protein domain specific binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ID3

5/16 Interacting proteins for ID3 (ENSP00000363689³) via UniProtKB, MINT, and/or STRING (see all 16 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TCF3	ENSP00000262965³	STRING (score=.989)
TCF4	ENSP00000346440³	STRING (score=.933)
ID4	ENSP00000367972³	STRING (score=.931)
BMP4	ENSP00000245451³	STRING (score=.926)
MYOD1	ENSP00000250003³	STRING (score=.894)

About this table

5/10 Gene Ontology (GO) biological process terms (links to tree view) (see all 10 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006275	regulation of DNA replication	IEA	--
GO:0007275	multicellular organismal development	TAS	1628620
GO:0007507	heart development	IEA	--
GO:0009611	response to wounding	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ID3
2 Novoseek chemical compound relationships for ID3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
oxygen	0.00	2	19054058 (2)
zinc	0.00	1	10575541 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ID3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ID3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002167

Sigma-Aldrich siRNA for ID3

Sigma-Aldrich shRNA for ID3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002167

REFSEQ mRNAs for ID3 gene:

NM_002167.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002167

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002167
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002167
                                 untagged cDNA clone in CMV expression vector: NM_002167

Additional cDNA sequence:

AK225965.1 AK290003.1 BC003107.1 BT006791.1 CR597388.1 CR603067.1 CR611504.1 CR612668.1

CR614670.1 CR615457.1 CR620515.1 CR623483.1 D28449.1 X66924.1 X69111.1

10 DOTS entries:

DT.448517 DT.92452265 DT.100817038 DT.100817039 DT.97855621 DT.95365730 DT.95365717 DT.121403793

DT.92452272 DT.95099597

24/562 AceView cDNA sequences (see all 562 ):

H89353 CA420836 CR623483 AA516007 BF061101 BQ008635 BQ014563 AA583583

AI949079 AA425764 AI077534 CR612668 BU733493 CR611504 AA987439 CD671237

CR614670 N50460 BQ005231 BM739564 BE221233 BF439510 CD671238 CR597388

highest scoring ESTs for ID3:

AA310279 AA525306 AA576713 AI992066 AL048518 AL697702 AL708993 AW163787 AW166245 AW328591

Unigene Cluster for ID3:

Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

Hs.76884 [show with all ESTs]

Unigene Representative Sequence: AK225965

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000374561

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ID3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ID3

¹ / ² / ³

3 probe-sets matching ID3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37043_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AL021154	0.20	1.00	0.72	1
207826_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002167	0.60	1.00	0.82	1
207826_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AACCACTGCT

SOURCE GeneReport for Unigene cluster: Hs.76884
Expression variation in blood from EXPOLDB for ID3
UniProtKB/Swiss-Prot: ID3_HUMAN, Q02535
Tissue specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ID3 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ID3¹	--	inhibitor of DNA binding 3, dominant negative helix-loop-helix more	92.16(n) 99.16(a)	403547 NM_001003025.1 NP_001003025.1
chimpanzee (Pan troglodytes)	ID3¹	--	inhibitor of DNA binding 3, dominant negative helix-loop-helix more	99.44(n) 99.16(a)	745532 XM_001165695.1 XP_001165695.1
cow (Bos taurus)	ID3¹	--	inhibitor of DNA binding 3, dominant negative helix-loop-helix more	91.6(n) 97.48(a)	538690 NM_001014950.1 NP_001014950.1
rat (Rattus norvegicus)	Id3¹	--	inhibitor of DNA binding 3	87.96(n) 97.48(a)	25585 NM_013058.2 NP_037190.1
mouse (Mus musculus)	Id3^{1, 5}	4 (66.00 cM)⁵	inhibitor of DNA binding 3^{1, 5}	88.52(n)¹ 96.64(a)¹	15903¹ NM_008321.1¹ NP_032347.1¹ AI173823⁵ AI839283⁵ (see all 22)

About this table Species with no ortholog for ID3

ENSEMBL Gene Tree for ID3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ID3 gene

ID1² ID2² ID4²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/56 NCBI SNPs in ID3 are shown (see all 56 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 39)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs11574^1,2	A,C,F,H,O	23758085(-)	`AGCTCG/ACTCCG`	1	A/T	mis¹		11	MN EU EA WA NA	1282
	rs2920^1,2	A,C,F,H	23757367(-)	`AGACTA/GAACCT`	1	--	ut3¹ ese³		18	MN EU EA WA NA	1776
	rs1050096^1,2	A,C,F,H	23757248(-)	`GGTCTT/CTTCAG`	1	--	ut3¹ ese³		16	MN EU EA WA NA	1546
	rs1555025^1,2	A,C,F,H	23759522(+)	`ATTGCG/TCTATT`	1	--	ng3¹		12	NA EA MN EU WA	1266
	rs2071495^1,2	C,F,H,O	23756920(-)	`AACTTG/CCTTAT`	1	--	ng5¹		13	EU EA WA NA	1154
	rs1555026^1,2	C,F,H	23759792(+)	`AATAGT/CTGCTT`	1	--	ng3¹		7	NA EA EU WA	650
	rs11542317^1,2	C,F,H	23758067(-)	`TCATCT/GCCAAC`	1	A/S	mis¹		9	EU EA WA NA	896
	rs2742948^1,2	C,F,H	23760774(+)	`ACTGCC/TTGGGG`	1	--	ng3¹ tfbs³		4	EU EA WA	414
	rs4649097^1,2	C,F,H	23760467(+)	`TAACCA/GAAGAG`	1	--	ng3¹ trp³		15	NA EU EA WA	1394
	rs2071494^1,2	C,F,H	23756956(-)	`CGCACA/GTGGCC`	1	--	ng5¹		7	NA EU EA WA	552

About this table

HapMap Linkage Disequilibrium images for ID3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600277

7 Novoseek disease relationships for ID3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
thyroid cancer	26.28	3	16394085 (2)
leukemia t-cell	23.50	2	8632670 (2)
lymphoma	15.20	2	15780199 (1), 8632670 (1)
tumors	12.35	13	18069898 (2), 16394085 (2), 15342397 (2), 18048329 (1) (see all 6)
retinoblastoma	7.87	2	12021231 (2)
adenocarcinoma	0.00	4	11751402 (2), 11161400 (1)
metastasis	0.00	1	15342397 (1)

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1 PharmGKB disease relationship for ID3 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

Genetic Association Database: ID3
Human Genome Epidemiology Navigator: ID3 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/132 PubMed articles for ID3 gene (see all 132 ):

Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development. (PubMed id 1628620)^{2, 3, 4} Ellmeier W.... Weith A. (1992)
Structural organisation and chromosomal mapping of the human Id-3 gene. (PubMed id 7828896)^{1, 3, 4} Deed R.W....Norton J.D. (1994)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
Analysis of candidate genes for prostate cancer. (PubMed id 15583422)^{3, 6} Burmester J.K....Catalona W.J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types. (PubMed id 8437843)^{3, 4} Deed R.W.... Norton J.D. (1993)
Expression of Id2 and Id3 mRNA in human lymphocytes. (PubMed id 8632670)^{1, 3} Ishiguro A....Koeffler H.P. (1995)
Estrogen-induced redox sensitive Id3 signaling controls the growth of vascular cells. (PubMed id 18281048)^{1, 3} Felty Q. and Porther N. (2008)
Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes. (PubMed id 16449966)^{1, 3} Simbulan-Rosenthal C.M....Rosenthal D.S. (2006)
Rho/Rho-associated kinase signal regulates myogenic differentiation via myocardin-related transcription factor-A/Smad-dependent transcription of the Id3 gene. (PubMed id 18477564)^{1, 3} Iwasaki K....Sobue K. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3399	HGNC: 5362	AceView: ID3	Ensembl:ENSG00000117318	euGenes: HUgn3399
ECgene: ID3	H-InvDB: ID3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ID3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ID3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ID3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ID3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ID3		Antibodies for ID3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ID3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Recombinant & Natural Proteins

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	Tagged/untagged cDNA clones
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	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ID3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ID3

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ID3 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for ID3

Summaries
for ID3

Genomic Location
for ID3

Proteins
for ID3

Protein Domains/
Families
for ID3

Gene Function
for ID3

Pathways & Interactions
for ID3

Drugs & Compounds
for ID3

Transcripts
for ID3

Expression
for ID3

Orthologs
for ID3

Paralogs
for ID3

SNPs/Variants
for ID3

Disorders & Mutations
for ID3

Medical News
for ID3

Publications
for ID3

Search for ID3

Genome Databases showing ID3

Other Databases showing ID3

Specialized Databases showing ID3

Licensable Technologies
for ID3

Services
for ID3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ID3 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor ID3

Summariesfor ID3

Genomic Locationfor ID3

Proteinsfor ID3

Protein Domains/Familiesfor ID3

Gene Functionfor ID3

Pathways & Interactionsfor ID3

Drugs & Compoundsfor ID3

Transcriptsfor ID3

Expression for ID3

Orthologsfor ID3

Paralogsfor ID3

SNPs/Variantsfor ID3

Disorders & Mutationsfor ID3

Medical Newsfor ID3

Publicationsfor ID3

Search for ID3

Genome Databases showing ID3

Other Databases showing ID3

Specialized Databases showing ID3

Licensable Technologiesfor ID3

Servicesfor ID3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ID3

Summaries
for ID3

Genomic Location
for ID3

Proteins
for ID3

Protein Domains/
Families
for ID3

Gene Function
for ID3

Pathways & Interactions
for ID3

Drugs & Compounds
for ID3

Transcripts
for ID3

Expression
for ID3

Orthologs
for ID3

Paralogs
for ID3

SNPs/Variants
for ID3

Disorders & Mutations
for ID3

Medical News
for ID3

Publications
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Licensable Technologies
for ID3

Services
for ID3