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inhibitor of DNA binding 2B, dominant negative helix-loop-helix...(Previous names: inhibitor of DNA binding 2B, dominant negative helix-loop-helix...)
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Aliases
for ID2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 2
| Aliases |
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| Inhibitor Of DNA Binding 2B, Dominant Negative Helix-Loop-Helix Protein(Pseudogene)1 2 | | Inhibitor Of DNA Binding 2B, Dominant Negative Helix-Loop-Helix Protein1 | | Inhibitor Of DNA Binding 2B3 |
| External Ids: | HGNC: 306561 | Entrez Gene: 840992 | UniProtKB: Q146023 | | ORGUL members: | |
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| NONCODE:n387280 | |
Export aliases for ID2B gene to outside databasesPrevious GC identifers: GC00U990986 GC03U900017 GC03M061964 GC03M062066 GC03M062067 GC03M062085
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Summaries
for ID2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for ID2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ID2B gene promoter:
E2F-4 E2F-3a E2F-5 CUTL1 E2F-2 AREB6 POU2F1 E2F E2F-1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ID2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ID2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p14.2 HGNC cytogenetic band: 3p21.1ID2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M062110: view genomic region
(about GC identifiers)
Start:
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62,109,158 bp from pter |
End:
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62,110,392 bp from pter |
Size:
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1,235 bases |
Orientation:
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minus strand |
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Proteins
for ID2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: ID2B_HUMAN, Q14602 (See
protein sequence)Recommended Name: Putative DNA-binding protein inhibitor ID-2B Size: 36 amino acids; 4055 Da
Caution: Could be the product of a pseudogene. Encoded by an intronless gene, it lacks the basic helix-loop-helix(bHLH) domain found in ID2Explore the universe of human proteins at neXtProt for ID2B: NX_Q14602
ID2B Protein expression data from MOPED and PaxDb: About this image 
Human Recombinant Protein Products:
ID2B Antibody Products:
Assay Products for ID2B: |
Protein
Domains /
Families
for ID2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ID2B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q14602ProtoNet protein and cluster: Q14602 |
Function
for ID2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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1 GenomeRNAi human phenotype for ID2B:
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Pathways & Interactions
for ID2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ID2B
|
Drugs & Compounds
for ID2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ID2B
Search CenterWatch for drugs/clinical trials and news about ID2B 
|
Transcripts
for ID2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ID2B gene: NM_001039082.1 Unigene Cluster for ID2B: Inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) Hs.591670 [show with all ESTs]Unigene Representative Sequence: M96843
Additional cDNA sequence: M96843.1 3 DOTS entries: DT.419995 DT.102824856 DT.92437995
GeneLoc Exon Structure
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Expression
for ID2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ID2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGAACTTTT
About this image
See ID2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ID2B
SOURCE GeneReport for Unigene cluster: Hs.591670
SABiosciences Custom PCR Arrays for ID2B
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ID2B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ID2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ID2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ID2B |
Orthologs
for ID2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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Paralogs
for ID2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ID2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ID2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ID2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed article for ID2B gene integrated from 9 sources:
(articles sorted by number of sources associating them with ID2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two distinct cDNA sequences encoding the human helix-loop-helix protein Id2. (PubMed id 8224921)1, 2, 3 Kurabayashi M.... Kedes L. (1993)
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External Searches for ID2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ID2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ID2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ID2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ID2B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ID2B gene:
Search GeneIP for patents involving ID2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ID2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ID2B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ID2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ID2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ID2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ID2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ID2B |
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| | | | Search Tocris compounds for ID2B |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for ID2B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ID2B |
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Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013
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