Aliases for ICOSLG Gene
External Ids for ICOSLG Gene
Previous HGNC Symbols for ICOSLG Gene
Previous GeneCards Identifiers for ICOSLG Gene
GeneCards Summary for ICOSLG Gene
ICOSLG (Inducible T-Cell Co-Stimulator Ligand) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and ICos-ICosL Pathway in T-Helper Cell. GO annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.
UniProtKB/Swiss-Prot for ICOSLG Gene
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).