Aliases for ICMT Gene
Aliases for ICMT Gene
External Ids for ICMT Gene
- HGNC: 5350
- Entrez Gene: 23463
- Ensembl: ENSG00000116237
- OMIM: 605851
- UniProtKB: O60725
Previous GeneCards Identifiers for ICMT Gene
- GC01M005857
- GC01M006090
- GC01M005990
- GC01M006215
- GC01M005429
Summaries for ICMT Gene
-
This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ICMT Gene
ICMT (Isoprenylcysteine Carboxyl Methyltransferase) is a Protein Coding gene. Diseases associated with ICMT include Legionaire Disease and Hallermann-Streiff Syndrome. Among its related pathways are G-protein signaling_H-RAS regulation pathway and Metabolism of proteins. GO annotations related to this gene include cAMP response element binding protein binding and protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity.
UniProtKB/Swiss-Prot for ICMT Gene
-
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ICMT Gene
Genomics for ICMT Gene
Regulatory Elements for ICMT Gene
Enhancers for ICMT Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ICMT on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ICMT gene promoter:
Regulatory Element Products
Genomic Location for ICMT Gene
- Chromosome:
- 1
- Start:
- 6,221,193 bp from pter
- End:
- 6,235,984 bp from pter
- Size:
- 14,792 bases
- Orientation:
- Minus strand
Genomic View for ICMT Gene
Genes around ICMT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.31 by Ensembl
- 1p36.31 by Entrez Gene
- 1p36.31 by HGNC
ICMT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ICMT Gene
Proteins for ICMT Gene
-
Protein details for ICMT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60725-ICMT_HUMAN
- Recommended name:
- Protein-S-isoprenylcysteine O-methyltransferase
- Protein Accession:
- O60725
- Q6FHT0
Protein attributes for ICMT Gene
- Size:
- 284 amino acids
- Molecular mass:
- 31938 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
- No Data Available
Protein Expression for ICMT Gene
Selected DME Specific Peptides for ICMT Gene
- O60725:
-
- SLIHFFGE
- RHPSYVG
- HTLVTSGVY
- GTQVMLCNP
- VPTGLPFIKGVK
- SFLLNHS
Post-translational modifications for ICMT Gene
Other Protein References for ICMT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ICMT
- Novus Biologicals Antibodies for ICMT
-
Abcam antibodies for ICMT
- Invitrogen Antibodies for ICMT
- antibodies-online Antibodies for ICMT: See all 46
- GeneTex ICMT antibody for ICMT
Protein Products
-
OriGene Purified Proteins for ICMT
- Search Origene for MassSpec and Protein Over-expression Lysates for ICMT
- Origene Custom Protein Services for ICMT
- antibodies-online Proteins for ICMT: See all 5
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- Search GeneTex for Proteins for ICMT
-
Abcam proteins for ICMT
Assay Products
- antibodies-online Kits for ICMT: See all 3
Domains & Families for ICMT Gene
Protein Domains for ICMT Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ICMT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O60725UniProtKB/Swiss-Prot:
ICMT_HUMAN :- Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
- Family:
-
- Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
No data available for Gene Families for ICMT Gene
Function for ICMT Gene
Molecular function for ICMT Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.
- UniProtKB/Swiss-Prot Function:
- Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Enzyme Numbers (IUBMB) for ICMT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity | TAS | 9614111 |
| GO:0004671 | protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity | TAS | -- |
| GO:0008168 | methyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for ICMT Gene
- MGI mutant phenotypes for ICMT:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for ICMT:
-
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Decreased ionizing radiation sensitivity
- Decreased viability ratio
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased viability after Maraba virus infection
- Decreased viability
- Decreased shRNA abundance
- Decreased shRNA abundance (Z-score < -2)
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ICMT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ICMT gene
- Search ViGene Biosciences for ICMT
CRISPR Products
-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for ICMT
- GenScript: Design CRISPR guide RNA sequences for ICMT
miRNA for ICMT Gene
- miRTarBase miRNAs that target ICMT
-
- hsa-mir-130b-3p (MIRT020175)
- hsa-mir-124-3p (MIRT022702)
- hsa-mir-93-5p (MIRT028069)
- hsa-mir-26b-5p (MIRT029560)
- hsa-mir-331-3p (MIRT043333)
- hsa-mir-1260b (MIRT052699)
- hsa-mir-4433b-5p (MIRT074491)
- hsa-mir-4475 (MIRT283557)
- hsa-mir-6504-3p (MIRT343357)
- hsa-mir-210-3p (MIRT440033)
- hsa-mir-218-5p (MIRT440471)
- hsa-mir-4436b-3p (MIRT475394)
- hsa-mir-6864-5p (MIRT475395)
- hsa-mir-3650 (MIRT475396)
- hsa-mir-6499-3p (MIRT475397)
- hsa-mir-873-5p (MIRT475398)
- hsa-mir-3179 (MIRT475399)
- hsa-mir-7515 (MIRT475400)
- hsa-mir-7845-5p (MIRT475401)
- hsa-mir-940 (MIRT475402)
- hsa-mir-6893-5p (MIRT475403)
- hsa-mir-6808-5p (MIRT475404)
- hsa-mir-3910 (MIRT475405)
- hsa-mir-3714 (MIRT475406)
- hsa-mir-506-3p (MIRT475407)
- hsa-mir-106b-5p (MIRT475408)
- hsa-mir-17-5p (MIRT475409)
- hsa-mir-20a-5p (MIRT475410)
- hsa-mir-20b-5p (MIRT475411)
- hsa-mir-519d-3p (MIRT475412)
- hsa-mir-526b-3p (MIRT475413)
- hsa-mir-106a-5p (MIRT475414)
- hsa-mir-6807-5p (MIRT523047)
- hsa-mir-6888-3p (MIRT523048)
- hsa-mir-7151-3p (MIRT523049)
- hsa-mir-5095 (MIRT523050)
- hsa-mir-3120-5p (MIRT523051)
- hsa-mir-1292-3p (MIRT523052)
- hsa-mir-6850-3p (MIRT523053)
- hsa-mir-4438 (MIRT523054)
- hsa-mir-1260a (MIRT529513)
- hsa-mir-4433a-5p (MIRT529514)
- hsa-mir-219b-5p (MIRT529515)
- hsa-mir-5009-3p (MIRT529516)
- hsa-mir-1224-3p (MIRT529517)
- hsa-mir-6834-3p (MIRT529518)
- hsa-mir-501-5p (MIRT529519)
- hsa-mir-508-5p (MIRT529520)
- hsa-mir-3145-5p (MIRT529521)
- hsa-mir-4797-5p (MIRT529522)
- hsa-mir-520e (MIRT529523)
- hsa-mir-520d-3p (MIRT529524)
- hsa-mir-520c-3p (MIRT529525)
- hsa-mir-520b (MIRT529526)
- hsa-mir-520a-3p (MIRT529527)
- hsa-mir-373-3p (MIRT529528)
- hsa-mir-372-3p (MIRT529529)
- hsa-mir-302e (MIRT529530)
- hsa-mir-302d-3p (MIRT529531)
- hsa-mir-302c-3p (MIRT529532)
- hsa-mir-302b-3p (MIRT529533)
- hsa-mir-302a-3p (MIRT529534)
- hsa-mir-519c-3p (MIRT529535)
- hsa-mir-519b-3p (MIRT529536)
- hsa-mir-519a-3p (MIRT529537)
miRNA Products
- Search ViGene Biosciences for ICMT
Inhibitory RNA Products
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Clone Products
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ICMT
- VectorBuilder custom plasmid, inducible vectors for ICMT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ICMT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ICMT
-
ViGene Biosciences adenoviral particle packaged cDNA for ICMT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ICMT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ICMT gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ICMT Gene
Localization for ICMT Gene
Subcellular locations from UniProtKB/Swiss-Prot for ICMT Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| plasma membrane | 3 |
| extracellular | 1 |
| nucleus | 1 |
| cytosol | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | IDA | 9614111 |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0016020 | membrane | TAS,IEA | 10441503 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for ICMT Gene
Pathways by source for ICMT Gene
3 Reactome pathways for ICMT Gene
1 KEGG pathway for ICMT Gene
3 GeneGo (Thomson Reuters) pathways for ICMT Gene
Interacting Proteins for ICMT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006464 | cellular protein modification process | TAS | 9614111 |
| GO:0006481 | C-terminal protein methylation | IEA,TAS | -- |
| GO:0006612 | protein targeting to membrane | TAS | 9614111 |
| GO:0032259 | methylation | IEA | -- |
| GO:0043687 | post-translational protein modification | TAS | -- |
No data available for SIGNOR curated interactions for ICMT Gene
Transcripts for ICMT Gene
mRNA/cDNA for ICMT Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (374) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ICMT Gene
CRISPR Products
-
OriGene CRISPR knockouts for ICMT
-
Santa Cruz Biotechnology (SCBT) CRISPR for ICMT
- GenScript: Design CRISPR guide RNA sequences for ICMT
miRNA Products
- Search ViGene Biosciences for ICMT
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ICMT
- Browse OriGene Inhibitory RNA Products For ICMT
-
ViGene Biosciences ready-to-package AAV shRNAs for ICMT gene
Clone Products
- Sino Biological Human cDNA Clone for ICMT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ICMT
- VectorBuilder custom plasmid, inducible vectors for ICMT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ICMT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||
| SP4: | - | - |
Expression for ICMT Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Hepatoblasts Liver Bud
-
Epithelial Cells
- Hepatoblasts Liver Bud
- Eye (Sensory Organs)
-
Fibroblasts (Uncategorized)
This gene is overexpressed in Lung (25.4) and Placenta (9.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ICMT Gene
NURSA nuclear receptor signaling pathways regulating expression of ICMT Gene:
ICMTSOURCE GeneReport for Unigene cluster for ICMT Gene:
Hs.515688mRNA Expression by UniProt/SwissProt for ICMT Gene:
O60725-ICMT_HUMAN
Tissue specificity:
Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.
Evidence on tissue expression from TISSUES for ICMT Gene
- Nervous system(4.6)
- Spleen(4.3)
- Blood(4.2)
- Lymph node(4.2)
- Lung(3.3)
- Skin(2.3)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for ICMT
-
OriGene qPCR primer pairs and template standards for ICMT
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ICMT Gene
Orthologs for ICMT Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ICMT 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ICMT 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Icmt 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Icmt 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ICMT 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ICMT 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ICMT 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ICMT 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | icmt 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC397717 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | icmt 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | ste14 34 35 |
|
||
| CG11268 36 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001310 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | M01E11.1 36 34 35 |
|
||
| F21F3.3 36 35 |
|
||||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | STE14 34 35 37 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AAR122C 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A02167g 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | STE14A 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0602900 34 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU00034 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | mam4 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10934 35 |
|
OneToOne |
- Species where no ortholog for ICMT was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ICMT Gene
No data available for Paralogs for ICMT Gene
Variants for ICMT Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000032691 | -- | 6,230,081(+) | GCCCA(C/G)GAGTT | intron-variant | |
| rs1000138378 | -- | 6,233,094(+) | TGTGA(C/T)CCACC | intron-variant | |
| rs1000430267 | -- | 6,232,982(+) | CCTCC(C/T)GAGTA | intron-variant | |
| rs1000521636 | -- | 6,235,958(+) | GCCCG(A/C/G)AGAAA | upstream-variant-2KB, utr-variant-5-prime | |
| rs1000763311 | -- | 6,234,166(+) | CACCG(C/T)GCCCG | intron-variant |
Residual Variation Intolerance Score:
56.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.92;
35.73% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ICMT Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ICMT
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ICMT Gene
Disorders for ICMT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| legionaire disease |
|
|
| hallermann-streiff syndrome |
|
|
Search ICMT in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ICMT
No data available for UniProtKB/Swiss-Prot and Genatlas for ICMT Gene
Publications for ICMT Gene
- Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum. (PMID: 9614111) Dai Q. … Philips M.R. (J. Biol. Chem. 1998) 2 3 4 22 64
- Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe. (PMID: 19158273) Wright L.P. … Philips M.R. (Mol. Cell. Biol. 2009) 3 4 22 64
- Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study. (PMID: 19841875) Fontaine-Bisson B. … Morange P.E. (J. Mol. Med. 2010) 3 46 64
- Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration. (PMID: 19651782) Cushman I. … Casey P.J. (J. Biol. Chem. 2009) 3 22 64
- An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). (PMID: 19161160) Franke B. … Blom H.J. (Birth Defects Res. Part A Clin. Mol. Teratol. 2009) 3 46 64
Products for ICMT Gene
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- GeneTex ICMT antibody for ICMT
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- ViGene Biosciences adenoviral particle packaged cDNA for ICMT gene
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- Search ViGene Biosciences for ICMT
- Horizon Cell Lines for ICMT
- Cyagen custom Knockout/knockin (KOKI) mouse models for ICMT
- VectorBuilder custom plasmid, inducible vectors for ICMT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ICMT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ICMT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer