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ICAM4 Gene

protein-coding   GIFtS: 57

GC19P010258
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
(Previous names: intercellular adhesion molecule 4, Landsteiner-Wiener blood group, Landsteiner-Wiener blood group, intercellular adhesion molecule 4 (LW blood group) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: LW)
Services    

Aliases &
Descriptions
for ICAM4

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CD242 1, 2
ICAM-4 3
LW 2, 3
Descriptions
CD242 antigen 2, 3
LW blood group protein 3
Landsteiner-Wiener blood group 1
Landsteiner-Wiener blood group antigen a 2
Landsteiner-Wiener blood group glycoprotein 2, 3
intercellular adhesion molecule 4 2
intercellular adhesion molecule 4 (LW blood group) 1, 2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood
group) 2
intercellular adhesion molecule 4, Landsteiner-Wiener blood
group 1
External Ids
HGNC: 53471
Entrez Gene: 33862
UniProtKB: Q147733
Ensembl: ENSG000001053717
Search outside databases for aliases for ICAM4 gene

Previous GC identifers: GC19P010519 GC19P010620 GC19P010242

Summaries
for ICAM4

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for ICAM4:
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the
immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion
molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to
the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens
is a single aa variation at position 100; Gln-100

UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773
Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin
alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins

Genomic Location
for ICAM4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ICAM4 gene  

Entrez Gene cytogenetic band: 19p13.2-cen   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2-cen

ICAM4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P010258:     (about GC identifiers)

Start:
 10,258,650 bp from pter
End:
 10,260,198 bp from pter
Size:
 1,549 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000019.8  NT_011295.10  

Proteins
for ICAM4

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773 (See protein sequence)
Recommended Name: Intercellular adhesion molecule 4 precursor  
Size: 271 amino acids; 29265 Da
Subcellular location: Isoform Long: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform Short: Secreted
Secondary accessions: A0M8X2 Q14771 Q14772 Q16375
Alternative splicing: 2 isoforms:  Q14773-1   Q14773-2   

Post-translational modifications:

  • N- and O-glycosylated1


    • REFSEQ proteins (3 alternative transcripts): 
    NP_001034221.1  NP_001535.1  NP_071772.1  


    ENSEMBL proteins: 
    ENSP00000342114 ENSP00000370147 ENSP00000377320 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ICAM4)
    Human Recombinant Proteins from Abnova (ICAM4)
                  OriGene Purified Recombinant Human Protein: ICAM4 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005886 plasma membrane TAS6431896
    GO:0016021 integral to membrane TAS6431896
    About this table

    Antibodies for ICAM4: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (ICAM4), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ICAM4)
    Novus Biologicals Antibody for ICAM4

    Assays for ICAM4: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for ICAM4

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro domains/families:
     IPR003987 ICAM_VCAM_N
     IPR013768 ICAM_N
     IPR013783 Ig-like_fold


       GeneDecks  ICAM4 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q14773

    ProtoNet protein and cluster: Q14773

    2 Blocks protein families:
    IPB003987 Intercellular adhesion molecule/vascular cell adhesion molecule-1 signature
    IPB013768 Intercellular adhesion molecule


    UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773
    Similarity: Belongs to the immunoglobulin superfamily. ICAM family
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains

    Gene Function
    for ICAM4

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ICAM4)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001039132

                  Applied Biosystems Silencer® siRNAs for ICAM4

                  Sigma-Aldrich siRNA and siRNA Panels for ICAM4  
                         Sigma-Aldrich shRNA for ICAM4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ICAM4
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001039132
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001039132
                                     untagged cDNA clones in CMV expression vector (see all 5): BC000046 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001039132

    UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773
    Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin
    alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins

    Genatlas biochemistry entry for ICAM4:
    adhesion molecule,intercellular 4

    1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Icam4):

    hematopoietic system

    2 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005178 integrin binding TAS8566017
    GO:0005515 protein binding IEA--
    About this table

    Pathways & Interactions
    for ICAM4

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  ICAM4 


    5/14 Interacting proteins for ICAM4 (ENSP000003421143) via UniProtKB, MINT, and/or STRING (see all 14 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHAGENSP000003602173STRING (score=.973)
    ITGB2ENSP000003472793STRING (score=.966)
    ITGA4ENSP000002335733STRING (score=.95)
    CD47ENSP000003553613STRING (score=.949)
    ITGALENSP000003492523STRING (score=.949)
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016337 cell-cell adhesion IEA--
    About this table

    Drugs & Compounds
    for ICAM4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ICAM4

    Transcripts
    for ICAM4

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ICAM4)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001039132

                  Sigma-Aldrich siRNA and siRNA Panels for ICAM4  
                         Sigma-Aldrich shRNA for ICAM4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001039132  NM_001544  NM_022377  

    REFSEQ mRNAs for ICAM4 gene (3 alternative transcripts): 

    NM_001039132.1   NM_001544.3   NM_022377.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001039132  NM_001544  NM_022377  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001039132
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001039132
                                     untagged cDNA clones in CMV expression vector (see all 5): BC000046 

    Additional cDNA sequence: 

    BC000046.2 BC029364.1 BT009816.1 L27670.1 L27671.1 

    3 DOTS entries:

    DT.405584  DT.92418895  DT.102822076 

    24/282 AceView cDNA sequences (see all 282 ):

    BP346334 BM855025 BM473834 AL701065 AW069267 BX360248 BU192598 BC015969 
    T28374 BI823891 CB265238 AI753618 BQ683708 AI753027 NM_022377 AA306799 
    CB529024 BF431004 CB529704 BQ961824 CK429562 BC029364 BQ962120 CA309669 

    highest scoring ESTs for ICAM4:

    BC000046 BC029364 BE314619 BF868352 BT009816 L27670 L27671 AI821753 BE278826 BG496630 

    Unigene Cluster for ICAM4:

    Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
    Hs.706750  [show with all ESTs]
    Unigene Representative Sequence: NM_022377


    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ICAM4

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b
    SP1:              -                     
    SP2:                                    

    About this scheme

    ECgene alternative splicing isoforms for ICAM4

    3 Ensembl transcripts including schematic representations:
    ENST00000340992  ENST00000380770  ENST00000393717  

    Expression
    for ICAM4

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ICAM4 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ICAM4

    1 / 2 / 3

    3 probe-sets matching ICAM4 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    35078_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 X93093 0.20 1.00 0.72 1

    		207194_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001544 0.60 1.00 0.82 1

    		207194_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ICAM4 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GTGGCTGACG

    SOURCE GeneReport for Unigene cluster: Hs.706750

    Expression variation in blood from EXPOLDB for ICAM4

    UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773
    Tissue specificity: Erythrocytes

    Orthologs
    for ICAM4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ICAM4 gene from 4 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 ICAM41   -- intercellular adhesion molecule 4 (Landsteiner-Wiener more 79.38(n)
    71.85(a)    		 611265  XM_848909.1  XP_854002.1 
    chimpanzee
    (Pan troglodytes)    		 ICAM41   -- intercellular adhesion molecule 4 (Landsteiner-Wiener more 98.59(n)
    97.88(a)    		 455698  XM_512364.2  XP_512364.2 
    cow
    (Bos taurus)    		 ICAM41   -- intercellular adhesion molecule 4 (Landsteiner-Wiener more 76.35(n)
    68.3(a)    		 514873  XM_592787.2  XP_592787.2 
    mouse
    (Mus musculus)    		 Icam41, 5 9 (8.00 cM)5
    		 intercellular adhesion molecule 4, Landsteiner-Wiener more1, 5 74.27(n)1
    70(a)1    		 783691  NM_023892.21  NP_076381.11 
     AF2962825  AF2962835  (see all 9)
    About this table        Species with no ortholog for ICAM4

    ENSEMBL Gene Tree for ICAM4

    Paralogs
    for ICAM4

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    		  --

    SNPs/Variants
    for ICAM4

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section

    		UniProtKB/Swiss-Prot: ICAM4_HUMAN, Q14773
    Polymorphism: Responsible for the Landsteiner-Wiener blood group system. The molecular basis of the
    LW(A)=LW5/LW(B)=LW7 blood group antigens is a single variation in position 100; Gln-100
    corresponds to LW(A) and Arg-100 to LW(B)


    9 NCBI SNPs in ICAM4 are shown
    (Click for Applied Biosystems TaqMan ® Genotyping Assay) (only AB snps)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 19 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs50303851,2
    		H10259608(+) CCACGC/GGGGTC 3 -- int1 ut316Minor allele frequency- G:0.00NS EU EA WA 510
    rs50303841,2
    		C,F,H10259089(+) TGAGGG/AACAGG 3 -- int18Minor allele frequency- A:0.01NS EU EA WA 606
    --
    rs560174831,2
    		--10259594(+) ACCAAA/GCGTGA 3 -- int1 ut310--------
    rs360233251,2
    		--10259439(+) AGCCCG/CTGATC 3 P/R L/V mis12Minor allele frequency- C:0.01NS 92
    rs357138171,2
    		--10258832(+) CCCTTA/CTGGGT 3 F/L mis10--------
    --
    rs558071181,2
    		--10259593(+) GACCAA/GGCGTG 3 -- int1 ut310--------
    rs343851351,2
    		--10259131(+) GCTGGA/CAGAGG 3 -- int12Minor allele frequency- C:0.01NS 94
    --
    rs556802701,2
    		--10259150(+) GGGTA-/TTTGAC 3 -- int10--------
    rs351654111,2
    		--10259206(+) CCTTGC/TCTTAG 3 -- int12Minor allele frequency- T:0.01NS 94
    About this table
    The following additional 85 SNP(s) have been found in Applied Biosystems data source:
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)


     rs281439 rs2569711 rs281437 rs3093030 rs2569702 rs11669397 rs5030400
     rs35956512 rs2569700 rs34925519 rs35099361 rs1801714 rs2071441 rs5501
     rs2735439 rs2569704 rs28432861 rs5494 rs2228615 rs5495 rs2916060
     rs13306429 rs11575074 rs885743 rs35078242 rs5498 rs2569694 rs710845
     rs2569695 rs1057981 rs1056536 rs36110042 rs2569706 rs281432 rs13306430
     rs5030364 rs2569703 rs12972990 rs34660244 rs2569709 rs2569698 rs35797244
     rs735747 rs2569708 rs281438 rs34274798 rs2569710 rs34918248 rs2075742
     rs2735444 rs2569701 rs35318566 rs2075741 rs2735443 rs35654716 rs1141533
     rs17852402 rs5030371 rs2569693 rs5030398 rs2071440 rs1056538 rs34797260
     rs3093033 rs10402760 rs5496 rs5030374 rs3093032 rs281440 rs35225729
     rs5499 rs901886 rs5492 rs28485475 rs2735440 rs36045754 rs2916058
     rs5497 rs2569697 rs5030399 rs2735442 rs34778003 rs1800019 rs34669551
     rs3810159

    HapMap Linkage Disequilibrium images for ICAM4 (up to first 250kb)

    Disorders & Mutations
    for ICAM4

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 111250

    Blood Group Antigen Gene Mutation Database (BGMUT) LW blood group system 
    Human Gene Mutation Database: ICAM4
    Human Genome Epidemiology Navigator: ICAM4 (2 documents)

    Medical News
    for ICAM4

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for ICAM4

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/24 PubMed articles for ICAM4 gene (see all 24 ):

    Search for ICAM4

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ICAM4

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 3386 HGNC: 5347 AceView: ICAM1andICAM4 Ensembl:ENSG00000105371 euGenes: HUgn3386
    ECgene: ICAM4 H-InvDB: ICAM4

    Other Databases showing ICAM4

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing ICAM4

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    dbRBC/BGMUThttp://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=lw
    SeattleSNPshttp://pga.gs.washington.edu/data/icam4/

    Licensable Technologies
    for ICAM4

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for ICAM4

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ICAM4:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ICAM4-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ICAM4 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ICAM4 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant & Natural Proteins  

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     Recombinant Proteins
    (ICAM4)
     Antibodies (ICAM4)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for ICAM4




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for ICAM4

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