Aliases for ICA1 Gene
External Ids for ICA1 Gene
Previous GeneCards Identifiers for ICA1 Gene
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
GeneCards Summary for ICA1 Gene
ICA1 (Islet Cell Autoantigen 1) is a Protein Coding gene. Diseases associated with ICA1 include Diabetes Mellitus and Diabetes Mellitus, Insulin-Dependent. Among its related pathways are Allograft rejection. Gene Ontology (GO) annotations related to this gene include protein domain specific binding. An important paralog of this gene is ICA1L.
UniProtKB/Swiss-Prot for ICA1 Gene
May play a role in neurotransmitter secretion.