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IBA57 Gene

protein-coding   GIFtS: 45
GCID: GC01P228354

IBA57, Iron-Sulfur Cluster Assembly Homolog (S. Cerevisiae)

(Previous name: chromosome 1 open reading frame 69)
(Previous symbol: C1orf69)
  See IBA57-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
IBA57, Iron-Sulfur Cluster Assembly Homolog (S. Cerevisiae)1 2     With A Mass Of 57kDa1
C1orf691 2 3 5     Iron-Sulfur Cluster Assembly Factor For Biotin Synthase- And
Aconitase-Like Mitochondrial Proteins, With A Mass Of 57kDa2
Iron-Sulfur Cluster Assembly Factor Homolog2 3     Putative Transferase C1orf69, Mitochondrial2
MMDS32 5     Putative Transferase CAF17, Mitochondrial2
Chromosome 1 Open Reading Frame 691     EC 2.1.-.-3
Iron-Sulfur Cluster Assembly Factor For Biotin Synthase- And
Aconitase-Like Mitochondrial Proteins1
     

External Ids:    HGNC: 273021   Entrez Gene: 2002052   Ensembl: ENSG000001818737   OMIM: 6153165   UniProtKB: Q5T4403   

Export aliases for IBA57 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IBA57 Gene:
IBA57 (IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with IBA57 include multiple mitochondrial dysfunctions syndrome 3. GO annotations related to this gene include aminomethyltransferase activity.

UniProtKB/Swiss-Prot: CAF17_HUMAN, Q5T440
Function: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster
assembly pathway




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_167186.2  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for IBA57
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for IBA57

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IBA57


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.13   Ensembl cytogenetic band:  1q42.13   HGNC cytogenetic band: 1q42.13

IBA57 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IBA57 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P228354:  view genomic region     (about GC identifiers)

Start:
228,353,429 bp from pter      End:
228,369,958 bp from pter
Size:
16,530 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CAF17_HUMAN, Q5T440 (See protein sequence)
Recommended Name: Putative transferase CAF17, mitochondrial precursor  
Size: 356 amino acids; 38155 Da

Explore the universe of human proteins at neXtProt for IBA57: NX_Q5T440

Explore proteomics data for IBA57 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IBA57 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001010867.1  
    ENSEMBL proteins: 
     ENSP00000355672   ENSP00000437347  

    IBA57 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for IBA57

     
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    antibodies-online proteins for IBA57 

     
    antibodies-online peptides for IBA57

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    antibodies-online antibodies for IBA57 (13 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR006222 GCV_T_N
     IPR017703 YgfZ/GcvT_CS
     IPR013977 GCV_T_C

    Graphical View of Domain Structure for InterPro Entry Q5T440

    ProtoNet protein and cluster: Q5T440

    UniProtKB/Swiss-Prot: CAF17_HUMAN, Q5T440
    Similarity: Belongs to the GcvT family. CAF17 subfamily


    Find genes that share domains with IBA57           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAF17_HUMAN, Q5T440
    Function: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster
    assembly pathway

         Enzyme Number (IUBMB): EC 2.1.-.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004047aminomethyltransferase activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with IBA57           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for IBA57:
     Decreased Wnt reporter activit  Decreased cell number 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for IBA57

    miRNA
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    miRTarBase miRNAs that target IBA57:
    hsa-let-7b-5p (MIRT051887), hsa-mir-93-5p (MIRT048883)

    Block miRNA regulation of human, mouse, rat IBA57 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate IBA57:
    hsa-miR-1233 hsa-miR-4252 hsa-miR-1827
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CAF17_HUMAN, Q5T440: Mitochondrion

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with IBA57           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IBA57
    Interactions:

        Search GeneGlobe Interaction Network for IBA57

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for IBA57 (Q5T4403 ENSP000003556724) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MINOS1Q5TGZ03, ENSP000003255624I2D: score=1 STRING: ENSP00000325562
    ISCA1ENSP000003651594STRING: ENSP00000365159
    ISCA2ENSP000002988184STRING: ENSP00000298818
    DDX43ENSP000003593614STRING: ENSP00000359361
    DDX53ENSP000003686674STRING: ENSP00000368667
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006546glycine catabolic process IEA--
    GO:0006783heme biosynthetic process IEA--

    Find genes that share ontologies with IBA57           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IBA57 (CAF17)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IBA57 gene: 
    NM_001010867.2  

    Unigene Clusters for IBA57:

    IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
    Hs.237017  [show with all ESTs], Hs.636881
    Unigene Representative Sequences: NM_001010867, AK023911
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366711(uc001hsl.4 uc010pvw.2) ENST00000484749 ENST00000546123

    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate IBA57:
    hsa-miR-1233 hsa-miR-4252 hsa-miR-1827
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    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat IBA57

    Additional mRNA sequence: AK023911.1 

    6 DOTS entries:

    DT.100733224  DT.75100419  DT.91922644  DT.91731859  DT.40130573  DT.100826912 

    Selected AceView cDNA sequences (see all 43):

    BQ023080 AI953035 AL583557 CR615475 CB240803 AW978541 BF592160 AW044301 
    BI820993 BM048834 BX378102 BI252345 AW104050 BU688568 AI038116 BM549690 
    AK022796 BQ647940 BU168166 AA831498 BQ023708 BX348276 BG697277 BG421070 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IBA57 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IBA57 Expression
    About this image


    IBA57 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    IBA57 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IBA57 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.237017 Hs.636881

    UniProtKB/Swiss-Prot: CAF17_HUMAN, Q5T440
    Tissue specificity: Expressed in skin fibroblasts and skeletal muscle (at protein level)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IBA57

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IBA57 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Iba571 , 5 RIKEN cDNA A230051G13 gene5
    IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)1
    76.97(n)1
    71.07(a)1
      11 (36.97 cM)5
    2167921  NM_173785.61  NP_776146.11 
     591553695 
    chicken
    (Gallus gallus)
    Aves IBA571 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 62.66(n)
    57.79(a)
      420396  NM_001030958.2  NP_001026129.2 
    lizard
    (Anolis carolinensis)
    Reptilia IBA576
    IBA57, iron-sulfur cluster assembly homolog (S. ce...
    49(a)
    1 ↔ 1
    6(3159478-3163549)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia iba571 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 57.45(n)
    54.95(a)
      100489125  XM_002939311.2  XP_002939357.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.143232 Transcribed sequence with weak similarity to protein more 76.62(n)    BI670948.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG80431 CG8043 48.98(n)
    37.63(a)
      41030  NM_141557.2  NP_649814.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F39H2.31 CELE_F39H2.3 40.86(n)
    34.63(a)
      172668  NM_059945.5  NP_492346.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes IBA57(YJR122W)4 Mitochondrial matrix protein involved in the incorporation more   --   10(649776-651269) 853586  NP_012656.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G121301 AT4G12130 45.37(n)
    38.13(a)
      826821  NM_117283.2  NP_192950.2 
    rice
    (Oryza sativa)
    Liliopsida Os06g01348001 Os06g0134800 47.19(n)
    39.06(a)
      4340033  NM_001063253.1  NP_001056718.1 


    ENSEMBL Gene Tree for IBA57 (if available)
    TreeFam Gene Tree for IBA57 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IBA57 (see all 381)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0698214
    Multiple mitochondrial dysfunctions syndrome 3 (MMDS3)4--see VAR_0698212 Q P mis40--------
    rs1911989971,2
    --228354590(+) TCTCTG/TCAGCT 1 -- int10--------
    rs1461145551,2
    --228354591(+) CTCTTA/CAGCTT 1 -- int10--------
    rs574502431,2
    C,F--228354636(+) TTTTAG/ATGACT 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1425706401,2
    --228354754(+) ATGTTA/CACATC 1 -- int10--------
    rs1807085371,2
    --228354827(+) GAACTC/GTGTTT 1 -- int10--------
    rs1509498461,2
    --228354905(+) TTTCCA/GTATCA 1 -- int10--------
    rs1161250891,2
    C,F--228354966(+) AATACG/AGCCCT 1 -- int11Minor allele frequency- A:0.03NA 120
    rs727578041,2
    --228354969(+) ACGGCC/TCTGAG 1 -- int10--------
    rs1147071591,2
    C,F--228354996(+) TGCCGG/ATGTTT 1 -- int11Minor allele frequency- A:0.09WA 118

    HapMap Linkage Disequilibrium report for IBA57 (228353429 - 228369958 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IBA57 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1008511CNV Deletion20482838
    esv4840CNV Deletion18987735
    esv2724262CNV Deletion23290073
    esv2724273CNV Deletion23290073
    esv1771567CNV Deletion17803354
    dgv538n71CNV Loss21882294
    nsv827019CNV Loss20364138
    nsv873256CNV Loss21882294
    nsv523935CNV Loss19592680
    nsv873257CNV Loss21882294

    Human Gene Mutation Database (HGMD): IBA57
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IBA57
    DNA2.0 Custom Variant and Variant Library Synthesis for IBA57

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615316   
    OMIM disorders: 615330  
    UniProtKB/Swiss-Prot: CAF17_HUMAN, Q5T440
  • Multiple mitochondrial dysfunctions syndrome 3 (MMDS3) [MIM:615330]: A severe disorder of systemic energy
    metabolism, resulting in weakness, respiratory failure, lack of neurologic development, lactic acidosis,
    hyperglycinemia and early death. Some patients show failure to thrive, pulmonary hypertension, hypotonia and
    irritability. Biochemical features include severe combined deficiency of the 2-oxoacid dehydrogenases, defective
    lipoic acid synthesis and reduction in activity of mitochondrial respiratory chain complexes. Note=The disease is
    caused by mutations affecting the gene represented in this entry

  • 1 disease for IBA57:    
    About MalaCards
    multiple mitochondrial dysfunctions syndrome 3


    Find genes that share disorders with IBA57           About GenesLikeMe


    Export disorders for IBA57 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IBA57 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with IBA57)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy. (PubMed id 23462291)1, 2 Ajit Bolar N....Van Coster R. (Hum. Mol. Genet. 2013)
    2. The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation. (PubMed id 22323289)1, 2 Sheftel A.D....Lill R. (Mol. Biol. Cell 2012)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. (PubMed id 22114354)1 Alkhaja A.K.... Deckers M. (Mol. Biol. Cell 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    10. Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. (PubMed id 19656490)1 Nilsson R....Mootha V.K. (Cell Metab. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 200205 HGNC: 27302 AceView: LOC200205 Ensembl:ENSG00000181873 euGenes: HUgn200205
    ECgene: IBA57 H-InvDB: IBA57

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IBA57 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IBA57 gene:
    Search GeneIP for patents involving IBA57

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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