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IAPP Gene

protein-coding GIFtS: 63

GC12P021417

islet amyloid polypeptide
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
AMYLIN ^¹, ²
Amylin ^³
DAP ^¹, ², ³
IAP ^¹, ²

Descriptions
Diabetes-associated peptide ^³
Insulinoma amyloid peptide ^³
Islet amyloid polypeptide (diabetes-associated peptide; amylin) ^²
islet amyloid polypeptide ^²

External Ids
HGNC: 5329¹
Entrez Gene: 3375²
UniProtKB: P10997³
Ensembl: ENSG00000121351⁷

Search outside databases for aliases for IAPP gene

Previous GC identifers: GC12P021811 GC12P021527 GC12P021426

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for IAPP:

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients

suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin

with the development of type II diabetes has been known for some time, a direct causative role for

amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid

(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular

cultured cells, an effect that may be relevant to the development of type II diabetes. [provided

by RefSeq]

UniProtKB/Swiss-Prot: IAPP_HUMAN, P10997

Function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in

muscle, while not affecting adipocyte glucose metabolism

Gene Wiki entry for IAPP (Amylin)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the IAPP gene

Entrez Gene cytogenetic band: 12p12.3-p12.1 Ensembl cytogenetic band: 12p12.1 HGNC cytogenetic band: 12p12.1

IAPP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P021417: (about GC identifiers)

Start:	21,417,085 bp from pter
End:	21,423,683 bp from pter
Size:	6,599 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_009714.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: IAPP_HUMAN, P10997 (See protein sequence)

Recommended Name: Islet amyloid polypeptide precursor

Size: 89 amino acids; 9806 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1KUW (3D)

2G48 (3D)

2KB8 (3D)

Secondary accessions: Q14598

REFSEQ proteins: NP_000406.1

ENSEMBL proteins:

ENSP00000240652

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for IAPP
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Amylin, NproAmylin)
	Human Recombinant Proteins from Abnova (IAPP)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005625	soluble fraction	TAS	2608057
GO:0043025	cell soma	IEA	--

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Antibodies for IAPP:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Amylin, NproAmylin), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibodies for IAPP

Assays for IAPP:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of IAPP
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P10997

ProtoNet protein and cluster: P10997

1 Blocks protein family: IPB000443 Islet amyloid protein (amylin) signature

UniProtKB/Swiss-Prot: IAPP_HUMAN, P10997

Similarity: Belongs to the calcitonin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IAPP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000415

Applied Biosystems Silencer® siRNAs for IAPP

Sigma-Aldrich siRNA for IAPP

Sigma-Aldrich shRNA for IAPP

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000415
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000415
untagged cDNA clone in CMV expression vector: NM_000415

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000415

UniProtKB/Swiss-Prot: IAPP_HUMAN, P10997

Function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in

muscle, while not affecting adipocyte glucose metabolism

Genatlas biochemistry entry for IAPP:

islet amyloid polypeptide

5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Iapp):

growth/size

hematopoietic system

homeostasis/metabolism

immune system

skeleton

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005179	hormone activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for IAPP

5/39 Interacting proteins for IAPP (ENSP00000240652³) via UniProtKB, MINT, and/or STRING (see all 39 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PDX1	ENSP00000370421³	STRING (score=.999)
RAMP1	ENSP00000254661³	STRING (score=.994)
RAMP3	ENSP00000242249³	STRING (score=.993)
RAMP2	ENSP00000253796³	STRING (score=.986)
CRCP	ENSP00000353589³	STRING (score=.972)

About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptosis	TAS	8152488
GO:0007165	signal transduction	TAS	10342886
GO:0007267	cell-cell signaling	TAS	2608057
GO:0019233	sensory perception of pain	IEA	--
GO:0045596	negative regulation of cell differentiation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for IAPP
10/36 Novoseek chemical compound relationships for IAPP gene (see all 36 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
i-app	95.66	321	10907112 (10), 7935487 (7), 1541234 (6), 7802654 (6) (see all 91)
ac 187	87.47	7	8882637 (2), 10433998 (1), 12611974 (1), 16492540 (1)
amylinamide	75.32	3	1646609 (3)
thioflavin t	71.73	5	9568695 (1), 16884500 (1), 11374584 (1), 19100955 (1)
liraglutide	71.21	3	16625817 (1), 18794593 (1), 15340100 (1)
glucose	69.44	263	10946889 (8), 1860552 (7), 8163050 (6), 1541239 (6) (see all 99)
incretin	66.30	11	17367252 (2), 7692203 (2), 16751350 (1), 17272793 (1) (see all 9)
enterostatin	65.24	4	9208352 (1), 15146610 (1), 15107726 (1), 8697060 (1)
c-peptide	64.66	26	9212327 (4), 15057546 (2), 18624122 (2), 9223392 (1) (see all 19)
tesaglitazar	58.35	1	16627399 (1)

About this table

2 PharmGKB drug compound relationships for IAPP gene

Drug compound	PharmGKB Relations	PubMed IDs for articles supporting these relationships
mercaptopurine	PD FA GN	12704389
methotrexate	PD FA GN	12704389

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (IAPP)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000415

Sigma-Aldrich siRNA for IAPP

Sigma-Aldrich shRNA for IAPP

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000415

REFSEQ mRNAs for IAPP gene:

NM_000415.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000415

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000415
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000415
                                 untagged cDNA clone in CMV expression vector: NM_000415

Additional cDNA sequence:

DQ516082.1 J04422.1 X14904.1 X14905.1

7 DOTS entries:

DT.95293617 DT.121183677 DT.100779782 DT.100779779 DT.429747 DT.99931396 DT.92435879

24/300 AceView cDNA sequences (see all 300 ):

BQ477320 BM509215 BU069957 CA943747 BI712710 BQ548622 BU947587 CB068861

BM263836 BM857649 CA942651 BM313621 CA952530 BU787662 X14904 BM512290

BI711363 BI324997 BM314212 CA776720 BQ478162 CB177247 CA776491 BM311687

highest scoring ESTs for IAPP:

AA429852 AA446156 AW582904 AW582958 BG187739 BG192865 BG215756 BG654456 BG655075 BG655484

Unigene Cluster for IAPP:

Islet amyloid polypeptide

Hs.46835 [show with all ESTs]

Unigene Representative Sequence: NM_000415

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for IAPP

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b
SP1:					-				-
SP2:					-
SP3:									-

About this scheme

ECgene alternative splicing isoforms for IAPP

1 Ensembl transcript including schematic representation:

ENST00000240652

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

IAPP expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IAPP

¹ / ² / ³

3 probe-sets matching IAPP gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37871_at²	U95-A	1	1.00	1.00	1.00	1.00	--	--	--	--	--
207062_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000415	0.60	1.00	0.82	1
207062_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks IAPP for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.46835
Expression variation in blood from EXPOLDB for IAPP

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for IAPP gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	IAPP¹	--	islet amyloid polypeptide	83.9(n) 82.02(a)	403909 XM_850487.1 XP_855580.1
chimpanzee (Pan troglodytes)	IAPP¹	--	islet amyloid polypeptide	98.88(n) 96.63(a)	741937 XM_001144800.1 XP_001144800.1
rat (Rattus norvegicus)	Iapp¹	--	islet amyloid polypeptide	74.71(n) 67.82(a)	24476 NM_012586.1 NP_036718.1
mouse (Mus musculus)	Iapp^{1, 5}	6 (62.00 cM)⁵	islet amyloid polypeptide^{1, 5}	76.25(n)¹ 68.97(a)¹	15874¹ NM_010491.1¹ NP_034621.1¹ BC027527⁵ BM569571⁵ (see all 9)
chicken (Gallus gallus)	IAPP¹	--	islet amyloid polypeptide	72.76(n) 69.51(a)	396362 NM_205397.1 NP_990728.1

About this table Species with no ortholog for IAPP

ENSEMBL Gene Tree for IAPP

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 147940

UniProtKB/Swiss-Prot: IAPP_HUMAN, P10997

IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic

patients and in insulinomas

10/60 Novoseek disease relationships for IAPP gene (see all 60 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
niddm	77.67	112	9589246 (4), 12534323 (4), 7705017 (3), 1950379 (3) (see all 62)
hyperglycemia	69.22	31	8842609 (2), 1534057 (1), 16492545 (1), 17617279 (1) (see all 24)
amyloid deposition	66.31	13	1541234 (2), 8111613 (1), 12941771 (1), 12706321 (1) (see all 10)
insulinoma	64.00	28	8317551 (3), 14507315 (3), 12941771 (2), 9166666 (1) (see all 19)
insulin resistance	62.89	52	8967027 (3), 8877314 (2), 2204154 (2), 9814997 (2) (see all 39)
hypoglycemia	61.81	12	16492545 (2), 1787825 (2), 16492543 (2), 8772580 (1) (see all 8)
hyperglucagonemia	60.84	5	12384827 (2), 8842609 (2), 11979398 (1)
diabetes mellitus	57.45	34	8152488 (2), 11772274 (2), 1737562 (1), 7594773 (1) (see all 29)
amyloidosis	55.23	12	9568695 (2), 19266159 (1), 15878744 (1), 8296225 (1) (see all 11)
impaired glucose tolerance	54.69	14	10946889 (4), 9568698 (2), 1756902 (1), 8877314 (1) (see all 8)

About this table

1 PharmGKB disease relationship for IAPP gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	PD FA GN	12704389

About this table

Human Gene Mutation Database: IAPP
Genetic Association Database: IAPP
Human Genome Epidemiology Navigator: IAPP (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

Collaborative Research Agreement to Discover Anti-Amyloid Compounds

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/597 PubMed articles for IAPP gene (see all 597 ):

Missense mutation of amylin gene (S20G) in Japanese NIDDM patients. (PubMed id 8772735)^{1, 3, 4, 6} Sakagashira S.... Nanjo K. (1996)
Characterization of the human islet amyloid polypeptide/amylin gene transcripts: identification of a new polyadenylation site. (PubMed id 1282806)^{1, 3, 4} Hoeppener J.W.M....Jansz H.S. (1992)
Islet amyloid polypeptide: structure and upstream sequences of the IAPP gene in rat and man. (PubMed id 2223885)^{1, 3, 4} van Mansfeld A.D.M.... Jansz H.S. (1990)
Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis. (PubMed id 15878744)^{1, 3, 6} Esapa C....Clark A. (2005)
S20G mutation of the amylin gene is associated with a lower body mass index in Korean type 2 diabetic patients. (PubMed id 12706321)^{1, 3, 6} Cho Y.M....Lee H.K. (2003)
Polymorphism in intron 2 of islet amyloid polypeptide gene is associated with lower low-density lipoprotein cholesterol in nondiabetic subjects and in type 2 diabetic patients. (PubMed id 12588049)^{1, 3, 6} Rojas I....Novials A. (2002)
Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin. (PubMed id 2039456)^{1, 3, 4} Hubbard J.A.M....Price N.C. (1991)
Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori. (PubMed id 12679865)^{3, 6} Poa N.R....Edgar P.F. (2003)
The islet amyloid polypeptide (amylin) gene S20G mutation in Chinese subjects: evidence for associations with type 2 diabetes and cholesterol levels. (PubMed id 11318791)^{3, 6} Lee S.C....Chan J.C. (2001)
Role of S20G mutation of amylin gene in insulin secretion, insulin sensitivity, and type II diabetes mellitus in Taiwanese patients. (PubMed id 9794116)^{3, 4} Chuang L.M.... Lin B.J. (1998)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3375	HGNC: 5329	AceView: IAPP	Ensembl:ENSG00000121351	euGenes: HUgn3375
ECgene: IAPP	H-InvDB: IAPP

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Amylin

Licensable Technologies for IAPP
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for IAPP:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for IAPP-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IAPP		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Proteins for IAPP
	Lentivirus-delivered shRNAs for IAPP		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for IAPP

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IAPP Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for IAPP

Summaries
for IAPP

Genomic Location
for IAPP

Proteins
for IAPP

Protein Domains/
Families
for IAPP

Gene Function
for IAPP

Pathways & Interactions
for IAPP

Drugs & Compounds
for IAPP

Transcripts
for IAPP

Expression
for IAPP

Orthologs
for IAPP

Paralogs
for IAPP

SNPs/Variants
for IAPP

Disorders & Mutations
for IAPP

Medical News
for IAPP

Publications
for IAPP

Search for IAPP

Genome Databases showing IAPP

Other Databases showing IAPP

Specialized Databases showing IAPP

Licensable Technologies
for IAPP

Services
for IAPP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

IAPP Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor IAPP

Summariesfor IAPP

Genomic Locationfor IAPP

Proteinsfor IAPP

Protein Domains/Familiesfor IAPP

Gene Functionfor IAPP

Pathways & Interactionsfor IAPP

Drugs & Compoundsfor IAPP

Transcriptsfor IAPP

Expression for IAPP

Orthologsfor IAPP

Paralogsfor IAPP

SNPs/Variantsfor IAPP

Disorders & Mutationsfor IAPP

Medical Newsfor IAPP

Publicationsfor IAPP

Search for IAPP

Genome Databases showing IAPP

Other Databases showing IAPP

Specialized Databases showing IAPP

Licensable Technologiesfor IAPP

Servicesfor IAPP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for IAPP

Summaries
for IAPP

Genomic Location
for IAPP

Proteins
for IAPP

Protein Domains/
Families
for IAPP

Gene Function
for IAPP

Pathways & Interactions
for IAPP

Drugs & Compounds
for IAPP

Transcripts
for IAPP

Expression
for IAPP

Orthologs
for IAPP

Paralogs
for IAPP

SNPs/Variants
for IAPP

Disorders & Mutations
for IAPP

Medical News
for IAPP

Publications
for IAPP

Licensable Technologies
for IAPP

Services
for IAPP