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Aliases for IAH1 Gene

Aliases for IAH1 Gene

  • Isoamyl Acetate-Hydrolyzing Esterase 1 Homolog (S. Cerevisiae) 2 3
  • EC 3.1.-.- 4
  • S 6

External Ids for IAH1 Gene

Summaries for IAH1 Gene

GeneCards Summary for IAH1 Gene

IAH1 (Isoamyl Acetate-Hydrolyzing Esterase 1 Homolog (S. Cerevisiae)) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity, acting on ester bonds.

UniProtKB/Swiss-Prot for IAH1 Gene

  • Probable lipase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IAH1 Gene

Genomics for IAH1 Gene

Genomic Location for IAH1 Gene

Start:
9,473,658 bp from pter
End:
9,507,230 bp from pter
Size:
33,573 bases
Orientation:
Plus strand

Genomic View for IAH1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IAH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IAH1 Gene

Regulatory Elements for IAH1 Gene

Proteins for IAH1 Gene

  • Protein details for IAH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2TAA2-IAH1_HUMAN
    Recommended name:
    Isoamyl acetate-hydrolyzing esterase 1 homolog
    Protein Accession:
    Q2TAA2
    Secondary Accessions:
    • B4DMV3

    Protein attributes for IAH1 Gene

    Size:
    248 amino acids
    Molecular mass:
    27599 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IAH1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IAH1 Gene

Proteomics data for IAH1 Gene at MOPED

Post-translational modifications for IAH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for IAH1 Gene

Domains for IAH1 Gene

Protein Domains for IAH1 Gene

UniProtKB/Swiss-Prot:

IAH1_HUMAN
Family:
  • Belongs to the GDSL lipolytic enzyme family. IAH1 subfamily.:
    • Q2TAA2
genes like me logo Genes that share domains with IAH1: view

No data available for Gene Families for IAH1 Gene

Function for IAH1 Gene

Molecular function for IAH1 Gene

UniProtKB/Swiss-Prot Function: Probable lipase.

Enzyme Numbers (IUBMB) for IAH1 Gene

Gene Ontology (GO) - Molecular Function for IAH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity --
GO:0016788 hydrolase activity, acting on ester bonds IEA --
genes like me logo Genes that share ontologies with IAH1: view

miRNA for IAH1 Gene

miRTarBase miRNAs that target IAH1

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for IAH1 Gene

Localization for IAH1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IAH1 Gene COMPARTMENTS Subcellular localization image for IAH1 gene
Compartment Confidence
extracellular 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for IAH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with IAH1: view

Pathways for IAH1 Gene

SuperPathways for IAH1 Gene

No Data Available

Interacting Proteins for IAH1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000417580%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000417580 Q2TAA2-IAH1_HUMAN for IAH1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for IAH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process --
GO:0008152 metabolic process --
GO:0016042 lipid catabolic process IEA --
genes like me logo Genes that share ontologies with IAH1: view

No data available for Pathways by source for IAH1 Gene

Transcripts for IAH1 Gene

mRNA/cDNA for IAH1 Gene

(2) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IAH1 Gene

Isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IAH1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - - - -
SP6: - - - - - - - -
SP7: - - - - - - - - -
SP8: - - - - - - - -
SP9: - - - - - -
SP10: -
SP11: - -

Relevant External Links for IAH1 Gene

GeneLoc Exon Structure for
IAH1
ECgene alternative splicing isoforms for
IAH1

Expression for IAH1 Gene

mRNA expression in normal human tissues for IAH1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for IAH1 Gene

SOURCE GeneReport for Unigene cluster for IAH1 Gene Hs.744980

genes like me logo Genes that share expressions with IAH1: view

Orthologs for IAH1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for IAH1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IAH1 36
  • 99.6 (n)
  • 100 (a)
IAH1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia IAH1 36
  • 82.26 (n)
  • 85.48 (a)
IAH1 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IAH1 36
  • 85.75 (n)
  • 90.73 (a)
IAH1 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Iah1 36
  • 82.8 (n)
  • 83.87 (a)
Iah1 16
Iah1 37
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IAH1 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IAH1 37
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Iah1 36
  • 81.45 (n)
  • 83.06 (a)
chicken
(Gallus gallus)
Aves IAH1 36
  • 70.49 (n)
  • 72.13 (a)
IAH1 37
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IAH1 37
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia iah1 36
  • 67.25 (n)
  • 64.63 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10296 36
zebrafish
(Danio rerio)
Actinopterygii Dr.14991 36
iah1 36
  • 61.45 (n)
  • 61.3 (a)
iah1 37
  • 60 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes IAH1 37
  • 33 (a)
OneToOne
IAH1 39
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G45920 36
  • 48.42 (n)
  • 45.25 (a)
rice
(Oryza sativa)
Liliopsida Os01g0214200 36
  • 52.1 (n)
  • 47.3 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8601 37
  • 40 (a)
OneToOne
Species with no ortholog for IAH1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IAH1 Gene

ENSEMBL:
Gene Tree for IAH1 (if available)
TreeFam:
Gene Tree for IAH1 (if available)

Paralogs for IAH1 Gene

No data available for Paralogs for IAH1 Gene

Variants for IAH1 Gene

Sequence variations from dbSNP and Humsavar for IAH1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1251 -- 9,488,692(+) TTCCA(A/G)AAGTG intron-variant, downstream-variant-500B
rs1129766 -- 9,474,641(+) TCCAT(A/C)ACCCA synonymous-codon, reference, upstream-variant-2KB, nc-transcript-variant
rs1815892 -- 9,476,599(+) GGGTA(G/T)GGCAG intron-variant
rs1815894 -- 9,487,358(-) TTAGG(C/T)AGAAA intron-variant
rs2276337 -- 9,481,554(-) CATAC(C/T)GAGCC intron-variant

Relevant External Links for IAH1 Gene

HapMap Linkage Disequilibrium report
IAH1

No data available for Structural Variations from Database of Genomic Variants (DGV) for IAH1 Gene

Disorders for IAH1 Gene

No disorders were found for IAH1 Gene.

No data available for UniProtKB/Swiss-Prot for IAH1 Gene

Publications for IAH1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  5. Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. (PMID: 24159190) SeppAolAo I. … LehtimAoki T. (Eur. Heart J. 2014) 3

Products for IAH1 Gene

Sources for IAH1 Gene

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