HYAL4 Gene
protein-coding GIFtS: 54
GCID: GC07P123469
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|
hyaluronoglucosaminidase 4
| |
Aliases
for HYAL4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hyaluronoglucosaminidase 41 2 | | Hyaluronidase 42 | | Chondroitin Sulfate Endo-Beta-N-Acetylgalactosaminidase2 3 | | Hyaluronidase-41 | | Chondroitin Sulfate Hydrolase2 3 | | Hyaluronoglucosaminidase-43 | | CSHY2 3 | | Hyal-43 | | EC 3.2.1.353 8 | | Hyaluronoglucosaminidase-43 | | Hyal-43 | | EC 3.2.18 |
Export aliases for HYAL4 gene to outside databasesPrevious GC identifers: GC07P121963 GC07P123025 GC07P123039 GC07P123014 GC07P123079 GC07P123272 GC07P117848 |
Summaries
for HYAL4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HYAL4:
This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degradehyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved incell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidaseactivity. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: HYAL4_HUMAN, Q2M3T9Function: Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitinsulfate hydrolase activity, The best substrate being the galactosaminidic linkage in the sequence of a trisulfatedtetrasaccharide
|
Genomic Views
for HYAL4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HYAL4 gene promoter:
AhR Arnt MEF-2A POU2F1 FOXO4 POU2F1b POU2F1a POU2F1c aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for HYAL4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HYAL4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q31.3 Ensembl cytogenetic band: 7q31.32 HGNC cytogenetic band: 7q31.3HYAL4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P123469: view genomic region
(about GC identifiers)
Start:
|
123,469,037 bp from pter |
End:
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123,517,532 bp from pter |
Size:
|
48,496 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 122,873,836-122,906,152 |
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Proteins
for HYAL4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HYAL4_HUMAN, Q2M3T9 (See
protein sequence)Recommended Name: Hyaluronidase-4 Size: 481 amino acids; 54249 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: D0VXG1 Q9UL99 Q9Y6T9Explore the universe of human proteins at neXtProt for HYAL4: NX_Q2M3T9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2M3T9
2 DME Specific Peptides for HYAL4 (Q2M3T9)
HYAL4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036401.2
ENSEMBL proteins: ENSP00000419522 ENSP00000417872 ENSP00000223026 ENSP00000417186 ENSP00000420264
Human Recombinant Protein Products for HYAL4:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
HYAL4 for ontologies About GeneDecksing
HYAL4 Antibody Products:
Assay Products for HYAL4: |
Protein
Domains /
Families
for HYAL4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HYAL4 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q2M3T9ProtoNet protein and cluster: Q2M3T9 1 Blocks protein family: IPB001968 Glycosyl hydrolase family 56 signature
UniProtKB/Swiss-Prot: HYAL4_HUMAN, Q2M3T9Similarity: Belongs to the glycosyl hydrolase 56 family |
Function
for HYAL4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: HYAL4_HUMAN, Q2M3T9Function: Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitinsulfate hydrolase activity, The best substrate being the galactosaminidic linkage in the sequence of a trisulfatedtetrasaccharideCatalytic activity: Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residuesin hyaluronateBiophysicochemical properties: pH dependence: Optimum pH is 4.5-5 (for chondroitin sulfate hydrolase activity);Temperature dependence: Optimum temperature is 37 degrees Celsius; Genatlas biochemistry entry for HYAL4:hyaluroglucosaminidase 4,differentially expressed in placenta and skeletal muscle,involved inglycosaminoglycancatabolism,clustered with HYAL1P1 and SPAM1
Enzyme Numbers (IUBMB): EC 3.2.1.351 2 EC 3.2.12
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004415 | hyalurononglucosaminidase activity |
IEA | -- |
HYAL4 for ontologies About GeneDecksing
Phenotypes:
5 GenomeRNAi human phenotypes for HYAL4:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HYAL4 (NM_012269) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HYAL4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HYAL4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HYAL4 |
|
Pathways & Interactions
for HYAL4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Articular Cartilage Extracellular Matrix | | | 2 | Glycosaminoglycan degradation | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  R&D Systems Pathway for HYAL4
2 
Kegg Pathways (Kegg details for HYAL4):
HYAL4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HYAL4
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for HYAL4 (ENSP000002230264) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005975 | carbohydrate metabolic process |
IEA | -- | | GO:0006027 | glycosaminoglycan catabolic process |
TAS | 10493834 | | GO:0007342 | fusion of sperm to egg plasma membrane |
IEA | -- |
HYAL4 for ontologies About GeneDecksing
|
Drugs & Compounds
for HYAL4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HYAL4
Search CenterWatch for drugs/clinical trials and news about HYAL4
|
Transcripts
for HYAL4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HYAL4 gene: NM_012269.2 Unigene Cluster for HYAL4: Hyaluronoglucosaminidase 4 Hs.28673 [show with all ESTs]Unigene Representative Sequence: AF0090105 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000489978 ENST00000488323 ENST00000223026(uc003vlc.3 uc011knz.2)
ENST00000476325 ENST00000483878
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HYAL4 (NM_012269) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HYAL4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HYAL4 |
Additional cDNA sequence: AB470346.1 AF009010.1 BC104788.1 BC104790.1 BC143654.1 2 DOTS entries: DT.310081 DT.121111654 14 AceView cDNA sequences: AI990387 AI033437 AA252101 AI381685 R66097 AA252069 BX117836 AA252100 NM_012269 AF009010 W92156 BG013757 W92155 R67698
GeneLoc Exon Structure
|
Expression
for HYAL4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HYAL4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATTTAACTG
About this image
See HYAL4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HYAL4
SOURCE GeneReport for Unigene cluster: Hs.28673
UniProtKB/Swiss-Prot: HYAL4_HUMAN, Q2M3T9Tissue specificity: Detected in placenta and skeletal muscle
SABiosciences Custom PCR Arrays for HYAL4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HYAL4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HYAL4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HYAL4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HYAL4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HYAL4 |
Orthologs
for HYAL4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for HYAL4 gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
HYAL46 |
-- |
71(a) |
1 ↔ 1 |
5(67267939-67281882) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1001498531 |
hyaluronidase-4-like |
59.22(n)
59.07(a) |
|
100149853 XM_001922088.2 XP_001922123.1 |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
26(a) |
1 → many |
Group14.3(803059-805153) |
worm
(Caenorhabditis elegans) |
Secernentea |
T22C8.23 |
hyaluronidase |
30(a) |
|
II(8614552-8617147) -- |
ENSEMBL Gene Tree for HYAL4 (if available)
TreeFam Gene Tree for HYAL4 (if available) |
Paralogs
for HYAL4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HYAL4 gene
- SPAM12 HYAL32 HYAL22 HYAL12
5 SIMAP similar genes for HYAL4 using alignment to 4 protein entries: HYAL4_HUMAN (see all proteins):HYAL2 LOC402588 SPAM1 HYAL1 HYAL3
HYAL4 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for HYAL4
PGOHUM00000233547
|
Genomic Variants
for HYAL4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HYAL4 (123469037 - 123517532 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HYAL4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HYAL4 |
|
Disorders
/ Diseases
for HYAL4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HYAL4 for disorders About GeneDecksing
OMIM gene information: 604510
OMIM disorders: --
6  diseases for HYAL4: About MalaCardsmucopolysaccharidosis type ix oxyphilic adenoma mucopolysaccharidosis prostate cancer
adenoma prostatitis
1 disease from the University of Copenhagen DISEASES database for HYAL4:Oxyphilic adenoma Human Genome Epidemiology (HuGE) Navigator: HYAL4 (1 document)
Export disorders for HYAL4 gene to outside databases
|
Publications
for HYAL4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HYAL4 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with HYAL4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31. (PubMed id 10493834)1, 2, 3 Csoka A.B.... Stern R. (1999)
- Identification of human hyaluronidase-4 as a novel ch ondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic li nkage in the trisulfated tetrasaccharide sequence. (PubMed id 19889881)1, 2, 9 Kaneiwa T....Yamada S. (2010)
- Human hyaluronidases: electrophoretic multiple forms in somatic tissues and body fluids. Evidence for conserved hyaluronidase potential N-glycosylation sites in different mammalian species. (PubMed id 10989127)1, 9 Fiszer-Szafarz B....Zou L. (2000)
- Identification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (convent ional hyaluronidase-4). (PubMed id 23086929)1 Kaneiwa T....Yamada S. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Structures of vertebrate hyaluronidases and their unique enzymatic mechanism of hydrolysis. (PubMed id 16104017)2 Jedrzejas M.J. and Stern R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for HYAL4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HYAL4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HYAL4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HYAL4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HYAL4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HYAL4 gene:
Search GeneIP for patents involving HYAL4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HYAL4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HYAL4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HYAL4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HYAL4 | | | OriGene Protein Over-expression Lysate for HYAL4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HYAL4 | | OriGene 3'-UTR Clone for HYAL4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HYAL4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HYAL4 | | OriGene Custom Protein Services for HYAL4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HYAL4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HYAL4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HYAL4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HYAL4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HYAL4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HYAL4 |
| |
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| | | | Search Tocris compounds for HYAL4 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | HYAL4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HYAL4 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for HYAL4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HYAL4 |
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