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HUNK Gene

protein-coding   GIFtS: 57
GCID: GC21P033245

Hormonally Up-Regulated Neu-Associated Kinase

(Previous name: hormonally upregulated Neu-associated kinase)
  Search for HUNK
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hormonally Up-Regulated Neu-Associated Kinase1 2     Hormonally Up-Regulated Neu Tumor-Associated Kinase2
Hormonally Upregulated Neu-Associated Kinase1 2     Hormonally Upregulated Neu Tumor-Associated Kinase2
Serine/Threonine-Protein Kinase MAK-V2 3     Serine/Threonine Protein Kinase MAK-V2
B192 3     MAKV3
EC 2.7.11.13 8     EC 2.7.118

External Ids:    HGNC: 133261   Entrez Gene: 308112   Ensembl: ENSG000001421497   OMIM: 6065325   UniProtKB: P570583   

Export aliases for HUNK gene to outside databases

Previous GC identifers: GC21P029823 GC21P032166 GC21P032167 GC21P018704


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HUNK Gene:
HUNK (hormonally up-regulated Neu-associated kinase) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is STK40.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NC_018932.2  NT_011512.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the HUNK gene promoter:
         AREB6   Spz1   AP-1   Pax-6   Sox9   MyoD   FOXO1a   FOXO1   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHUNK promoter sequence
   Search Chromatin IP Primers for HUNK

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HUNK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.1   Ensembl cytogenetic band:  21q22.11   HGNC cytogenetic band: 21q22.1

HUNK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HUNK gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P033245:  view genomic region     (about GC identifiers)

Start:
33,245,628 bp from pter      End:
33,416,946 bp from pter
Size:
171,319 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HUNK_HUMAN, P57058 (See protein sequence)
Recommended Name: Hormonally up-regulated neu tumor-associated kinase  
Size: 714 amino acids; 79686 Da

Explore the universe of human proteins at neXtProt for HUNK: NX_P57058

Explore proteomics data for HUNK at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys483
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for HUNK (P57058) (see all 9)
     KIYEKKR  VVHRDLK  KRPNIQQ  GEPAAPG 


    See HUNK Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055401.1  
    ENSEMBL proteins: 
     ENSP00000270112   ENSP00000411860   ENSP00000408219  

    HUNK Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for HUNK

     
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    Cloud-Clone Corp. ELISAs for HUNK
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    Search eBioscience for ELISAs for HUNK 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: hormonally up-regulated Neu-associated kinase
    HUNK subfamily

    5 InterPro protein domains:
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry P57058

    ProtoNet protein and cluster: P57058

    UniProtKB/Swiss-Prot: HUNK_HUMAN, P57058
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with HUNK           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HUNK_HUMAN, P57058
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with HUNK           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for HUNK:
     Decreased substrate adherent c  Increased cell death in HCC-19 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hunk):
     normal  tumorigenesis 

    Find genes that share phenotypes with HUNK           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hunktm1Lach for HUNK

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HUNK
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    Selected qRT-PCR Assays for microRNAs that regulate HUNK (see all 52):
    hsa-miR-576-3p hsa-miR-3607-3p hsa-miR-376b hsa-miR-548k hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-128 hsa-miR-628-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----

    Find genes that share ontologies with HUNK           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HUNK
    Interactions:

        Search GeneGlobe Interaction Network for HUNK

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for HUNK (P570582, 3 ENSP000002701124) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RABEP1Q152763, ENSP000002624774I2D: score=2 STRING: ENSP00000262477
    CFL1ENSP000003096294STRING: ENSP00000309629
    LIMK1ENSP000003367404STRING: ENSP00000336740
    PPP2CAENSP000004184474STRING: ENSP00000418447
    PPP2R1AENSP000003248044STRING: ENSP00000324804
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007165signal transduction TAS10662544
    GO:0007275multicellular organismal development TAS10662544
    GO:0009103lipopolysaccharide biosynthetic process ----

    Find genes that share ontologies with HUNK           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HUNK

    2 HMDB Compounds for HUNK    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HUNK gene: 
    NM_014586.1  

    Unigene Cluster for HUNK:

    Hormonally up-regulated Neu-associated kinase
    Hs.109437  [show with all ESTs]
    Unigene Representative Sequence: AJ271722
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270112(uc002yph.3) ENST00000430354 ENST00000465574 ENST00000439107

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate HUNK (see all 52):
    hsa-miR-576-3p hsa-miR-3607-3p hsa-miR-376b hsa-miR-548k hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-128 hsa-miR-628-3p
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    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat HUNK
      QuantiFast Probe-based Assays in human, mouse, rat HUNK

    Additional mRNA sequence: 

    AF086072.1 AJ271722.1 

    3 DOTS entries:

    DT.40272011  DT.99965214  DT.102827642 

    Selected AceView cDNA sequences (see all 45):

    BM721431 AJ271722 AA026437 NM_014586 BF337824 CD656415 AI275788 CD625792 
    N22405 BX492801 AW136599 BQ437302 BQ650402 BQ890524 CD625794 CD625796 
    CD625800 AI669454 BF529471 CD625798 BM677084 AI868739 BE745128 BQ644781 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HUNK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTTGTTC
    HUNK Expression
    About this image


    HUNK expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Epithalamus
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Kidney (Urinary System)
             Metanephros
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced cells
    HUNK Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HUNK Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.109437
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HUNK gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hunk1 , 5 hormonally upregulated Neu-associated kinase1, 5 87.35(n)1
    92.44(a)1
      16 (51.71 cM)5
    265591  NM_015755.21  NP_056570.11 
     903863975 
    chicken
    (Gallus gallus)
    Aves HUNK1 hormonally up-regulated Neu-associated kinase 69.96(n)
    69.06(a)
      418493  XM_003640478.2  XP_003640526.2 
    lizard
    (Anolis carolinensis)
    Reptilia HUNK6
    hormonally up-regulated Neu-associated kinase
    68(a)
    1 ↔ 1
    3(145488587-145564551)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.243222 Xenopus laevis transcribed sequence with strong similarity more 80.38(n)    BJ072362.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hunk6
    hormonally up-regulated Neu-associated kinase
    47(a)
    1 ↔ 1
    10(34641111-34650021) ENSDARG00000091317
    fruit fly
    (Drosophila melanogaster)
    Insecta trbl6
    tribbles
    19(a)
    1 → many
    3L(20389388-20394709)
    worm
    (Caenorhabditis elegans)
    Secernentea DC2.7a3 protein kinase 39(a)   V(227272-234497)   --


    ENSEMBL Gene Tree for HUNK (if available)
    TreeFam Gene Tree for HUNK (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HUNK gene
    STK402  TRIB32  NUAK12  PRKAA22  TRIB12  PRKAA12  NUAK22  TRIB22  
    MELK2  
    Selected SIMAP similar genes for HUNK using alignment to 5 protein entries:     HUNK_HUMAN (see all proteins) (see all similar genes):
    MARK3    MARK2    RPS6KA5    MARK4    PRKAA1    DAPK3
    DKFZp564L2416    SIK3    STK38L    CHEK2    BRSK2    KIAA0999
    NUAK1    STK33    RPS6KA2    PRKCH    RPS6KA4    PNCK

    Find genes that share paralogs with HUNK           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for HUNK
    PGOHUM00000243689


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HUNK (see all 2972)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs722824041,2
    C--33243651(+) TTTTT-/T/TT  
            
    TTTTT
    1 -- us2k10--------
    rs711931541,2
    C--33243670(+) TTTTT-/T/TG  
            
    GAGAA
    1 -- us2k11NA 2
    rs1153413411,2
    F--33243738(+) ACTTTC/TGCCTC 1 -- us2k11Minor allele frequency- T:0.06WA 118
    rs1872513641,2
    C--33243739(+) CTTTCA/GCCTCC 1 -- us2k10--------
    rs1909214631,2
    --33243901(+) TGCCTC/TGGCCT 1 -- us2k10--------
    rs1406670701,2
    --33243951(+) GGCCTC/TAGAGT 1 -- us2k10--------
    rs1457562401,2
    --33244031(+) CACCAC/TGCTAG 1 -- us2k10--------
    rs1510876911,2
    C--33244046(+) CATTCC/TCCTCC 1 -- us2k10--------
    rs1408021811,2
    --33244101(+) TAAAAG/TGATTG 1 -- us2k10--------
    rs119097531,2
    C,F,H--33244130(+) AGTCAA/CGGCCG 1 -- us2k12Minor allele frequency- C:0.08NA WA 120

    HapMap Linkage Disequilibrium report for HUNK (33245628 - 33416946 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for HUNK (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2723341CNV Deletion23290073
    esv2723338CNV Deletion23290073
    esv2060229CNV Deletion18987734
    esv998414CNV Deletion20482838
    esv2723340CNV Deletion23290073
    esv1172635CNV Deletion17803354
    nsv3492CNV Insertion18451855
    nsv834081CNV Loss17160897
    nsv510793CNV Loss20534489
    nsv518119CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606532    OMIM disorders: --


    Find genes that share disorders with HUNK           About GenesLikeMe

    Genetic Association Database (GAD): HUNK
    Human Genome Epidemiology (HuGE) Navigator: HUNK (2 documents)

    Export disorders for HUNK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HUNK gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with HUNK)
        Utopia: connect your pdf to the dynamic
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    1. Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. (PubMed id 21107309)1, 4 McClay J.L....van den Oord E.J. (Neuropsychopharmacology 2011)
    2. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PubMed id 21490949)1, 4 Sim X....Tai E.S. (PLoS Genet. 2011)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8. (PubMed id 19890347)1, 4 Birlea S.A....Spritz R.A. (J. Invest. Dermatol. 2010)
    5. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (J. Proteome Res. 2007)
    6. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 3 Hattori M.... Yaspo M.-L. (Nature 2000)
    7. Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. (PubMed id 10662544)1, 3 Gardner H.P....Chodosh L.A. (Genomics 2000)
    8. HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. (PubMed id 20133759)1, 9 Quintela-Fandino M....Mak T.W. (Proc. Natl. Acad. Sci. U.S.A. 2010)
    9. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 30811 HGNC: 13326 AceView: HUNK Ensembl:ENSG00000142149 euGenes: HUgn30811
    ECgene: HUNK H-InvDB: HUNK

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HUNK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HUNK gene:
    Search GeneIP for patents involving HUNK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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