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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HUNK Gene

protein-coding   GIFtS: 57
GCID: GC21P033245

Hormonally Up-Regulated Neu-Associated Kinase

(Previous name: hormonally upregulated Neu-associated kinase)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Hormonally Up-Regulated Neu-Associated Kinase1 2     Hormonally Up-Regulated Neu Tumor-Associated Kinase2
Hormonally Upregulated Neu-Associated Kinase1 2     Hormonally Upregulated Neu Tumor-Associated Kinase2
Serine/Threonine-Protein Kinase MAK-V2 3     Serine/Threonine Protein Kinase MAK-V2
B192 3     MAKV3
EC 2.7.11.13 8     EC 2.7.118

External Ids:    HGNC: 133261   Entrez Gene: 308112   Ensembl: ENSG000001421497   OMIM: 6065325   UniProtKB: P570583   

Export aliases for HUNK gene to outside databases

Previous GC identifers: GC21P029823 GC21P032166 GC21P032167 GC21P018704


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HUNK Gene: 
HUNK (hormonally up-regulated Neu-associated kinase) is a protein-coding gene. Diseases associated with HUNK include septic arthritis, and vitiligo. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding. An important paralog of this gene is TSSK6.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000021.8  NC_018932.2  NT_011512.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HUNK gene promoter:
         AREB6   Spz1   AP-1   Pax-6   Sox9   MyoD   FOXO1a   FOXO1   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHUNK promoter sequence
   Search SABiosciences Chromatin IP Primers for HUNK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HUNK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.1   Ensembl cytogenetic band:  21q22.11   HGNC cytogenetic band: 21q22.1

HUNK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HUNK gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P033245:  view genomic region     (about GC identifiers)

Start:
33,245,628 bp from pter      End:
33,416,946 bp from pter
Size:
171,319 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HUNK_HUMAN, P57058 (See protein sequence)
Recommended Name: Hormonally up-regulated neu tumor-associated kinase  
Size: 714 amino acids; 79686 Da

Explore the universe of human proteins at neXtProt for HUNK: NX_P57058

Explore proteomics data for HUNK at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P57058

  • 4/9 DME Specific Peptides for HUNK (P57058) (see all 9)
     KIYEKKR  VVHRDLK  KRPNIQQ  GEPAAPG 

    HUNK Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HUNK Protein Expression
    REFSEQ proteins: NP_055401.1  
    ENSEMBL proteins: 
     ENSP00000270112   ENSP00000411860   ENSP00000408219  

    Human Recombinant Protein Products for HUNK: 
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    Novus Biologicals HUNK Protein
    Novus Biologicals HUNK Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HUNK 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----

    HUNK for ontologies           About GeneDecksing



    HUNK Antibody Products: 
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    Assay Products for HUNK: 
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    Cloud-Clone Corp. CLIAs for HUNK


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: hormonally up-regulated Neu-associated kinase 
    HUNK subfamily

    5 InterPro protein domains:
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry P57058

    ProtoNet protein and cluster: P57058

    UniProtKB/Swiss-Prot: HUNK_HUMAN, P57058
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily
    Similarity: Contains 1 protein kinase domain


    HUNK for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HUNK_HUMAN, P57058
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IEA--
         
    HUNK for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for HUNK:
     Decreased substrate adherent c  Increased cell death in HCC-19 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Hunk):
     normal  tumorigenesis 

    HUNK for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Hunktm1Lach for HUNK

       inGenious Targeting Laboratory - Custom generated mouse model solutions for HUNK 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HUNK

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HUNK 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HUNK 

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    hsa-miR-576-3p hsa-miR-3607-3p hsa-miR-376b hsa-miR-548k hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-128 hsa-miR-628-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HUNK

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for HUNK (P570582, 3 ENSP000002701124) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RABEP1Q152763, ENSP000002624774I2D: score=2 STRING: ENSP00000262477
    CFL1ENSP000003096294STRING: ENSP00000309629
    LIMK1ENSP000003367404STRING: ENSP00000336740
    PPP2CAENSP000004184474STRING: ENSP00000418447
    PPP2R1AENSP000003248044STRING: ENSP00000324804
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007165signal transduction TAS10662544
    GO:0007275multicellular organismal development TAS10662544
    GO:0009103lipopolysaccharide biosynthetic process ----

    HUNK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HUNK

    2 HMDB Compounds for HUNK    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--

    Search CenterWatch for drugs/clinical trials and news about HUNK

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HUNK gene: 
    NM_014586.1  

    Unigene Cluster for HUNK:

    Hormonally up-regulated Neu-associated kinase
    Hs.109437  [show with all ESTs]
    Unigene Representative Sequence: AJ271722
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270112(uc002yph.3) ENST00000430354 ENST00000465574 ENST00000439107

    miRNA
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    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate HUNK (see all 52):
    hsa-miR-576-3p hsa-miR-3607-3p hsa-miR-376b hsa-miR-548k hsa-miR-513a-5p hsa-miR-218-1* hsa-miR-128 hsa-miR-628-3p
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HUNK
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HUNK

    Additional mRNA sequence: 

    AF086072.1 AJ271722.1 

    3 DOTS entries:

    DT.40272011  DT.99965214  DT.102827642 

    24/45 AceView cDNA sequences (see all 45):

    AA026437 AJ271722 BM721431 NM_014586 BX492801 BF337824 AW136599 CD625800 
    CD625794 CD656415 CD625790 BQ890524 N22405 CD625796 CD625792 AI868739 
    BM677084 AI275788 BQ437302 AF086072 BQ650402 CD625798 BF529471 BQ644781 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HUNK expression in normal human tissues (normalized intensities)      HUNK embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTTGTTC
    HUNK Expression
    About this image


    HUNK expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Epithalamus
             brain/midbrain   
     
     Kidney (Urinary System)
             Metanephros
     
     Endothelium (Cardiovascular System)
             Endothelial progenitor cells ( Derivation and purification of endothelial precursor...
     
     Placenta (Extraembryonic Tissues)
             Decidua-derived mesenchymal cells
     
     Mesenchymal Stem Cells (Muscoskeletal System)
             Decidua-derived mesenchymal cells

    See HUNK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HUNK

    SOURCE GeneReport for Unigene cluster: Hs.109437
        SABiosciences Custom PCR Arrays for HUNK
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HUNK gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hunk1 , 5 hormonally upregulated Neu-associated kinase1, 5 87.35(n)1
    92.44(a)1
      16 (51.71 cM)5
    265591  NM_015755.21  NP_056570.11 
     903863975 
    chicken
    (Gallus gallus)
    Aves HUNK1 hormonally upregulated Neu-associated kinase 68.66(n)
    66.27(a)
      418493  XM_003640478.1  XP_003640526.1 
    lizard
    (Anolis carolinensis)
    Reptilia HUNK6
    --
    Uncharacterized protein
    68(a)
    59(a)
    1 ↔ 1
    possible ortholog
    3(145488587-145564551)
    1(196614554-196634738)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.243222 Xenopus laevis transcribed sequence with strong similarity more 80.38(n)    BJ072362.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hunk1 hormonally up-regulated Neu-associated kinase 57.96(n)
    54.45(a)
      564235  XM_687579.4  XP_692671.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HSL16
    KCC46
    (see all 3)
    Nim1p-related protein kinase that regulates the mo...
    Protein kinase of the bud neck involved in the sep...
    (see all 3)
    7(a)
    10(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    XI(248920-253476)
    III(79162-82275)


    ENSEMBL Gene Tree for HUNK (if available)
    TreeFam Gene Tree for HUNK (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HUNK gene
    TSSK62  TSSK32  TSSK1B2  MELK2  TSSK22  TSSK42  
    18/93 SIMAP similar genes for HUNK using alignment to 5 protein entries:     HUNK_HUMAN (see all proteins) (see all similar genes):
    MARK3    MARK2    RPS6KA5    MARK4    PRKAA1    DAPK3
    DKFZp564L2416    SIK3    STK38L    CHEK2    BRSK2    KIAA0999
    NUAK1    STK33    RPS6KA2    PRKCH    RPS6KA4    PNCK

    HUNK for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HUNK
    PGOHUM00000243689


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2972 SNPs in HUNK are shown (see all 2972)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs722824041,2
    C--33243651(+) TTTTT-/T/TT  
            
    TTTTT
    1 -- us2k10--------
    rs711931541,2
    C--33243670(+) TTTTT-/T/TG  
            
    GAGAA
    1 -- us2k11NA 2
    rs1153413411,2
    F--33243738(+) ACTTTC/TGCCTC 1 -- us2k11Minor allele frequency- T:0.06WA 118
    rs1872513641,2
    C--33243739(+) CTTTCA/GCCTCC 1 -- us2k10--------
    rs1909214631,2
    --33243901(+) TGCCTC/TGGCCT 1 -- us2k10--------
    rs1406670701,2
    --33243951(+) GGCCTC/TAGAGT 1 -- us2k10--------
    rs1457562401,2
    --33244031(+) CACCAC/TGCTAG 1 -- us2k10--------
    rs1510876911,2
    C--33244046(+) CATTCC/TCCTCC 1 -- us2k10--------
    rs1408021811,2
    --33244101(+) TAAAAG/TGATTG 1 -- us2k10--------
    rs119097531,2
    C,F,H--33244130(+) AGTCAA/CGGCCG 1 -- us2k12Minor allele frequency- C:0.08NA WA 120

    HapMap Linkage Disequilibrium report for HUNK (33245628 - 33416946 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for HUNK (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2723341CNV Deletion23290073
    esv2723338CNV Deletion23290073
    esv2060229CNV Deletion18987734
    esv998414CNV Deletion20482838
    esv2723340CNV Deletion23290073
    esv1172635CNV Deletion17803354
    nsv3492CNV Insertion18451855
    nsv834081CNV Loss17160897
    nsv510793CNV Loss20534489
    nsv518119CNV Loss19592680

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606532    OMIM disorders: --

    5 diseases for HUNK:    About MalaCards
    septic arthritis    vitiligo    alcoholism    schizophrenia
    arthritis


    HUNK for disorders           About GeneDecksing

    Genetic Association Database (GAD): HUNK
    Human Genome Epidemiology (HuGE) Navigator: HUNK (2 documents)

    Export disorders for HUNK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HUNK gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with HUNK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide pharmacogenomic study of neurocognition a s an indicator of antipsychotic treatment response in schizophrenia. (PubMed id 21107309)1, 4 McClay J.L....van den Oord E.J. (2011)
    2. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PubMed id 21490949)1, 4 Sim X....Tai E.S. (2011)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximit y to IDDM8. (PubMed id 19890347)1, 4 Birlea S.A....Spritz R.A. (2010)
    5. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (2007)
    6. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 3 Hattori M....Yaspo M.L. (2000)
    7. Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. (PubMed id 10662544)1, 3 Gardner H.P....Chodosh L.A. (2000)
    8. HUNK suppresses metastasis of basal type breast cance rs by disrupting the interaction between PP2A and cofilin-1. (PubMed id 20133759)1, 9 Quintela-Fandino M....Mak T.W. (2010)
    9. Loci associated with N-glycosylation of human immunogl obulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (2013)
    10. Proteomics strategy to identify substrates of LNX, a P DZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)1 Guo Z....Gao Y. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 30811 HGNC: 13326 AceView: HUNK Ensembl:ENSG00000142149 euGenes: HUgn30811
    ECgene: HUNK H-InvDB: HUNK

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HUNK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HUNK gene:
    Search GeneIP for patents involving HUNK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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