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Aliases for HULC Gene

Subcategory (RNA class) for HULC Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HULC Gene

  • Hepatocellular Carcinoma Up-Regulated Long Non-Coding RNA 2 3 5
  • Hepatocellular Carcinoma Associated Transcript 1 (Non-Protein Coding) 2 3
  • Highly Up-Regulated In Liver Cancer Long Non-Coding RNA 2 3
  • Long Intergenic Non-Protein Coding RNA 78 2 3
  • Highly Up-Regulated In Liver Cancer (Non-Protein Coding) 3
  • Non-Protein Coding RNA 78 2
  • NCRNA00078 3
  • LINC00078 3
  • HCCAT1 3

External Ids for HULC Gene

Previous GeneCards Identifiers for HULC Gene

  • GC06P008598

Summaries for HULC Gene

GeneCards Summary for HULC Gene

HULC (Hepatocellular Carcinoma Up-Regulated Long Non-Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

Gene Wiki entry for HULC Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HULC Gene

Genomics for HULC Gene

Regulatory Elements for HULC Gene

Enhancers for HULC Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around HULC on UCSC Golden Path with GeneCards custom track

Genomic Location for HULC Gene

Chromosome:
6
Start:
8,652,137 bp from pter
End:
8,653,846 bp from pter
Size:
1,710 bases
Orientation:
Plus strand

Genomic View for HULC Gene

Genes around HULC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HULC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HULC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HULC Gene

Proteins for HULC Gene

Post-translational modifications for HULC Gene

No Post-translational modifications

No data available for DME Specific Peptides for HULC Gene

Domains & Families for HULC Gene

Gene Families for HULC Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HULC: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HULC Gene

Function for HULC Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HULC Gene

Localization for HULC Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HULC Gene

Pathways & Interactions for HULC Gene

SuperPathways for HULC Gene

No Data Available

Interacting Proteins for HULC Gene

Gene Ontology (GO) - Biological Process for HULC Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HULC Gene

Drugs & Compounds for HULC Gene

No Compound Related Data Available

Transcripts for HULC Gene

mRNA/cDNA for HULC Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HULC Gene

Highly up-regulated in liver cancer long non-coding RNA:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HULC Gene

No ASD Table

Relevant External Links for HULC Gene

GeneLoc Exon Structure for
HULC
ECgene alternative splicing isoforms for
HULC

Expression for HULC Gene

mRNA expression in normal human tissues for HULC Gene

mRNA differential expression in normal tissues according to GTEx for HULC Gene

This gene is overexpressed in Liver (x49.9).

SOURCE GeneReport for Unigene cluster for HULC Gene Hs.214343

genes like me logo Genes that share expression patterns with HULC: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for HULC Gene

Orthologs for HULC Gene

Evolution for HULC Gene

ENSEMBL:
Gene Tree for HULC (if available)
TreeFam:
Gene Tree for HULC (if available)

No data available for Orthologs for HULC Gene

Paralogs for HULC Gene

No data available for Paralogs for HULC Gene

Variants for HULC Gene

Relevant External Links for HULC Gene

HapMap Linkage Disequilibrium report
HULC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for HULC Gene

Disorders for HULC Gene

Relevant External Links for HULC

Genetic Association Database (GAD)
HULC
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HULC

No disorders were found for HULC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HULC Gene

Publications for HULC Gene

  1. Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1). (PMID: 23728852) HAommerle M. … Diederichs S. (Hepatology 2013) 2 3 67
  2. Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. (PMID: 17241883) Panzitt K. … Zatloukal K. (Gastroenterology 2007) 2 3
  3. Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway. (PMID: 25592151) Cui M. … Zhang X. (Cancer Res. 2015) 3
  4. Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer. (PMID: 25874495) Kang M. … Yin J. (Tumour Biol. 2015) 3
  5. Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC. (PMID: 26317792) Gandhy S.U. … Safe S. (Oncotarget 2015) 3

Products for HULC Gene

Sources for HULC Gene

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