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Aliases for HTR6 Gene

Aliases for HTR6 Gene

  • 5-Hydroxytryptamine Receptor 6 2 3 5
  • 5-Hydroxytryptamine (Serotonin) Receptor 6, G Protein-Coupled 2 3
  • Serotonin Receptor 6 3 4
  • 5-HT6 3 4
  • 5-Hydroxytryptamine (Serotonin) Receptor 6 2
  • 5-HT6R 3
  • 5-HT-6 4

External Ids for HTR6 Gene

Previous GeneCards Identifiers for HTR6 Gene

  • GC01P019551
  • GC01P019016
  • GC01P019137
  • GC01P019461
  • GC01P019737
  • GC01P019864
  • GC01P019991
  • GC01P018237

Summaries for HTR6 Gene

Entrez Gene Summary for HTR6 Gene

  • This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

GeneCards Summary for HTR6 Gene

HTR6 (5-Hydroxytryptamine Receptor 6) is a Protein Coding gene. Diseases associated with HTR6 include Acute Stress Disorder and Amnestic Disorder. Among its related pathways are Serotonergic synapse and Monoamine GPCRs. GO annotations related to this gene include G-protein coupled receptor activity and histamine receptor activity. An important paralog of this gene is DRD5.

UniProtKB/Swiss-Prot for HTR6 Gene

  • This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

Tocris Summary for HTR6 Gene

  • Serotonin 5-HT6 receptors are located primarily in the striatum, olfactory tubercles, nucleus accumbens and hippocampus. Functions of 5-HT6 receptors include modulation of cholinergic and dopaminergic neurotransmission, and a role in spatial learning and memory.

Gene Wiki entry for HTR6 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HTR6 Gene

Genomics for HTR6 Gene

Regulatory Elements for HTR6 Gene

Enhancers for HTR6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G019687 0.7 ENCODE 36.1 +23.3 23335 2.6 BCOR SMARCA5 CBX3 ZNF280D PTBP1 ZMYM3 SALL2 RELA HDAC2 CBX5 HTR6 PIR33395 GC01P019759
GH01G019659 1.4 Ensembl ENCODE dbSUPER 17.5 -5.5 -5520 1.3 HDAC1 HDGF PKNOX1 ATF1 CBX3 ARID4B ZNF48 RAD21 RFX5 GLIS2 HTR6 GC01M019654
GH01G019432 2 FANTOM5 Ensembl ENCODE dbSUPER 10.8 -213.4 -213446 39.4 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 MEF2D SSRP1 RCOR2 CAPZB NBL1 OTUD3 RNU4-28P EMC1 HTR6 AKR7A2 AKR7A3 PQLC2 UBR4
GH01G019642 1.6 Ensembl ENCODE dbSUPER 11.2 -16.6 -16646 11.7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A ZNF2 YY1 ZNF416 ZNF143 OTUD3 EMC1 HTR6 NBL1 GC01M019654
GH01G019422 1.6 Ensembl ENCODE dbSUPER 10.2 -238.2 -238207 8.6 FOXA2 PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF766 FOS SP5 CAPZB RNU4-28P HTR6 AKR7A2 RN7SL277P PIR41915
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HTR6 on UCSC Golden Path with GeneCards custom track

Genomic Location for HTR6 Gene

Chromosome:
1
Start:
19,665,287 bp from pter
End:
19,680,966 bp from pter
Size:
15,680 bases
Orientation:
Plus strand

Genomic View for HTR6 Gene

Genes around HTR6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HTR6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HTR6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HTR6 Gene

Proteins for HTR6 Gene

  • Protein details for HTR6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P50406-5HT6R_HUMAN
    Recommended name:
    5-hydroxytryptamine receptor 6
    Protein Accession:
    P50406
    Secondary Accessions:
    • Q13640
    • Q5TGZ1

    Protein attributes for HTR6 Gene

    Size:
    440 amino acids
    Molecular mass:
    46954 Da
    Quaternary structure:
    • Interacts with MTOR, RPTOR and NF1 (PubMed:23027611). Interacts with CDK5 (By similarity).

neXtProt entry for HTR6 Gene

Post-translational modifications for HTR6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HTR6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HTR6 Gene

Domains & Families for HTR6 Gene

Protein Domains for HTR6 Gene

Suggested Antigen Peptide Sequences for HTR6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P50406

UniProtKB/Swiss-Prot:

5HT6R_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with HTR6: view

Function for HTR6 Gene

Molecular function for HTR6 Gene

GENATLAS Biochemistry:
5-hydroxytrhyptamine (serotonin) receptor,subtype 6,prominently expressed in the caudal nucleus,G protein coupled receptor superfamily,activating adenylate cyclase
UniProtKB/Swiss-Prot Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

Gene Ontology (GO) - Molecular Function for HTR6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004969 histamine receptor activity TAS 8522988
GO:0004993 G-protein coupled serotonin receptor activity IBA --
GO:0005515 protein binding IPI 17189269
GO:0030594 neurotransmitter receptor activity IBA --
genes like me logo Genes that share ontologies with HTR6: view
genes like me logo Genes that share phenotypes with HTR6: view

Animal Models for HTR6 Gene

MGI Knock Outs for HTR6:

Animal Model Products

  • Taconic Biosciences Mouse Models for HTR6

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR6
  • Applied Biological Materials Clones for HTR6

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for HTR6 Gene

Localization for HTR6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HTR6 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HTR6 gene
Compartment Confidence
plasma membrane 5
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for HTR6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 8522988
GO:0005929 cilium IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with HTR6: view

Pathways & Interactions for HTR6 Gene

genes like me logo Genes that share pathways with HTR6: view

Gene Ontology (GO) - Biological Process for HTR6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS 8522988
GO:0007268 chemical synaptic transmission TAS 8522988
GO:0021795 cerebral cortex cell migration ISS,IEA --
genes like me logo Genes that share ontologies with HTR6: view

No data available for SIGNOR curated interactions for HTR6 Gene

Drugs & Compounds for HTR6 Gene

(150) Drugs for HTR6 Gene - From: DrugBank, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Olanzapine Approved, Investigational Pharma Antagonist, agonist, Target, antagonist 399
Risperidone Approved, Investigational Pharma Antagonist, antagonist SR-2A inhibitor 492
Clozapine Approved Pharma Antagonist, antagonist, Target Antipsychotic medication 117
Iloperidone Approved Pharma Antagonist, antagonist, Target Dopamine (D2) and serotonin (5HT2) receptor antagonist 0
Asenapine Approved Pharma Antagonist, antagonist, Target Inhibits adrenergic receptor/5-HT receptor 54

(3) Additional Compounds for HTR6 Gene - From: IUPHAR and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
5-HT
Full agonist, Agonist

(5) Tocris Compounds for HTR6 Gene

Compound Action Cas Number
EMD 386088 hydrochloride Potent 5-HT6 agonist 1171123-46-8
SB 258585 hydrochloride Potent, selective 5-HT6 antagonist 1216468-02-8
SB 399885 hydrochloride Potent and selective 5-HT6 antagonist 402713-81-9
ST 1936 oxalate Selective, high affinity 5-HT6 agonist 1210-81-7
WAY 208466 dihydrochloride Selective 5-HT6 agonist 1207064-61-6

(83) ApexBio Compounds for HTR6 Gene

Compound Action Cas Number
(±)-MDMA hydrochloride 92279-84-0
2-Methyl-5-hydroxytryptamine hydrochloride 845861-49-6
Asenapine Inhibits adrenergic receptor/5-HT receptor 85650-56-2
BGC 20-761 5-HT6 antagonist,selective and high affinity 17375-63-2
Bilobalide Neuroprotective agent 33570-04-6
Blonanserin Atypical antipsychotic 132810-10-7
BTS 54-505 hydrochloride Potent SNRI,sibutramine metabolite 84484-78-6
Cisapride 81098-60-4
Clomipramine HCl SERT/NET dopamine transporter (DAT) blocker 17321-77-6
Clozapine N-oxide Metabolite of clozapine 34233-69-7
Dapoxetine HCl Selective serotonin reuptake inhibitor 129938-20-1
Desvenlafaxine 93413-62-8
Desvenlafaxine Succinate 386750-22-7
Dexfenfluramine hydrochloride 3239-45-0
Dihydroergotamine mesylate 6190-39-2
DOB hydrochloride 29705-96-2
DOI hydrochloride 42203-78-1
Duloxetine HCl 136434-34-9
Eltoprazine hydrochloride 98206-09-8
EMD 386088 hydrochloride 1171123-46-8
EMDT oxalate 263744-72-5
Escitalopram Oxalate Serotonin(5-HT) reuptake (SSRI) inhibitor 219861-08-2
Fenspiride HCl 5053-08-7
Fluoxetine HCl Serotonin reuptake inhibitor,selective 56296-78-7
Fluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant 61718-82-9
GR 46611 185259-85-2
Iloperidone hydrochloride 1299470-39-5
Ketanserin 74050-98-9
Lorcaserin HCl 846589-98-8
Lu AE58054 5-HT(6)R antagonist 467459-31-0
Lu AE58054 Hydrochloride 5-HT(6)R antagonist 467458-02-2
LY310762 192927-92-7
m-CPP hydrochloride 13078-15-4
Metergoline 17692-51-2
Methysergide maleate 129-49-7
Milnacipran HCl 101152-94-7
Mosapride Citrate 5-HT receptor agonist 112885-42-4
MS 245 oxalate 275363-58-1
NAD 299 hydrochloride 184674-99-5
Naratriptan 143388-64-1
NPS ALX Compound 4a dihydrochloride 299433-10-6
Olanzapine 132539-06-1
Ondansetron 99614-02-5
Palonosetron HCl 135729-62-3
Pizotifen Malate 5189-11-7
Psilocin 520-53-6
R 1485 dihydrochloride
Risperidone SR-2A inhibitor 106266-06-2
Rizatriptan Benzoate 145202-66-0
Ro 04-6790 202466-68-0
RS 39604 hydrochloride 167710-87-4
RS 67333 hydrochloride 168986-60-5
RU 24969 66611-26-5
Sarpogrelate hydrochloride 135159-51-2
SB 200646 hydrochloride 143797-62-0
SB 203186 hydrochloride 207572-69-8
SB 204070 148688-01-1
SB 242084 1215566-78-1
SB 243213 dihydrochloride 200940-23-4
SB 258585 hydrochloride 1216468-02-8
SB 258719 hydrochloride 1217674-10-6
SB 271046 hydrochloride Selective 5-HT6 antagonist 209481-24-3
SB 399885 hydrochloride 402713-81-9
SB271046 209481-20-9
SB742457 5-HT6 receptor antagonist,highly selective and high affinity 607742-69-8
SEA0400 Specific inhibitor of Na+/Ca2+ exchange 223104-29-8
Sertraline HCl 79559-97-0
SGS 518 oxalate 445441-27-0
ST 1936 oxalate 1210-81-7
Tandospirone Anxiolytic and antidepressant reagent 87760-53-0
Tianeptine sodium 5-HT uptake facilitator,selective,antidepressant 30123-17-2
Trazodone HCl Antidepressant 25332-39-2
Tropisetron 105826-92-4
Urapidil HCl 64887-14-5
Venlafaxine Dual serotonin/noradrenalin re-uptake inhibitor 99300-78-4
Vortioxetine 5-HT receptors antagonist 508233-74-7
Vortioxetine (Lu AA21004) HBr 5-HT receptor modulator, antidepressant and anxiolytic 960203-27-4
VUF 10166 155584-74-0
WAY 208466 dihydrochloride 1207064-61-6
WY 45233 succinate 448904-47-0
Ziprasidone HCl Serotonin and dopamine receptor antagonist 122883-93-6
Ziprasidone hydrochloride monohydrate 5-HT (serotonin)/dopamine receptor antagonist 138982-67-9
Zolmitriptan 139264-17-8
genes like me logo Genes that share compounds with HTR6: view

Drug Products

Transcripts for HTR6 Gene

mRNA/cDNA for HTR6 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HTR6 Gene

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR6
  • Applied Biological Materials Clones for HTR6

Alternative Splicing Database (ASD) splice patterns (SP) for HTR6 Gene

No ASD Table

Relevant External Links for HTR6 Gene

GeneLoc Exon Structure for
HTR6
ECgene alternative splicing isoforms for
HTR6

Expression for HTR6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HTR6 Gene

mRNA differential expression in normal tissues according to GTEx for HTR6 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x11.9), Brain - Putamen (basal ganglia) (x10.9), Brain - Caudate (basal ganglia) (x8.7), and Brain - Cortex (x4.7).

NURSA nuclear receptor signaling pathways regulating expression of HTR6 Gene:

HTR6

SOURCE GeneReport for Unigene cluster for HTR6 Gene:

Hs.22180

mRNA Expression by UniProt/SwissProt for HTR6 Gene:

P50406-5HT6R_HUMAN
Tissue specificity: Expressed in several human brain regions, most prominently in the caudate nucleus.

Evidence on tissue expression from TISSUES for HTR6 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with HTR6: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for HTR6 Gene

Orthologs for HTR6 Gene

This gene was present in the common ancestor of animals.

Orthologs for HTR6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HTR6 34 35
  • 98.94 (n)
cow
(Bos Taurus)
Mammalia HTR6 34 35
  • 89.7 (n)
dog
(Canis familiaris)
Mammalia HTR6 34 35
  • 89.19 (n)
rat
(Rattus norvegicus)
Mammalia Htr6 34
  • 88.32 (n)
mouse
(Mus musculus)
Mammalia Htr6 34 16 35
  • 86.45 (n)
oppossum
(Monodelphis domestica)
Mammalia HTR6 35
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia HTR6 35
  • 50 (a)
OneToOne
chicken
(Gallus gallus)
Aves HTR6 34 35
  • 69.85 (n)
lizard
(Anolis carolinensis)
Reptilia HTR6 35
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia htr6 34
  • 68.41 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC568269 34
  • 65.32 (n)
htr6 35
  • 49 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta DopR 36
  • 37 (a)
CG6989 36
  • 33 (a)
worm
(Caenorhabditis elegans)
Secernentea ser-5 35
  • 22 (a)
ManyToMany
ser-6 35
  • 20 (a)
ManyToMany
Species where no ortholog for HTR6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HTR6 Gene

ENSEMBL:
Gene Tree for HTR6 (if available)
TreeFam:
Gene Tree for HTR6 (if available)

Paralogs for HTR6 Gene

Paralogs for HTR6 Gene

(8) SIMAP similar genes for HTR6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HTR6: view

Variants for HTR6 Gene

Sequence variations from dbSNP and Humsavar for HTR6 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000265157 -- 19,670,852(+) TGCAG(C/T)GTACA intron-variant
rs1000316231 -- 19,671,094(+) GTACA(A/G)ACATT intron-variant
rs1000380701 -- 19,664,953(+) CCGCC(C/G)GGCCC upstream-variant-2KB
rs1000602665 -- 19,672,311(+) CCCGC(C/T)TTTCC intron-variant
rs1000654851 -- 19,672,549(+) GCCAG(G/T)GCTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HTR6 Gene

Variant ID Type Subtype PubMed ID
nsv508991 CNV insertion 20534489
nsv545729 CNV loss 21841781
nsv954899 CNV deletion 24416366

Variation tolerance for HTR6 Gene

Residual Variation Intolerance Score: 31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.45; 28.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HTR6 Gene

Human Gene Mutation Database (HGMD)
HTR6
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HTR6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HTR6 Gene

Disorders for HTR6 Gene

MalaCards: The human disease database

(3) MalaCards diseases for HTR6 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
acute stress disorder
  • traumatic stress disorder
amnestic disorder
  • amnesia
schizophrenia
  • schizophrenia 12
- elite association - COSMIC cancer census association via MalaCards
Search HTR6 in MalaCards View complete list of genes associated with diseases

Relevant External Links for HTR6

Genetic Association Database (GAD)
HTR6
Human Genome Epidemiology (HuGE) Navigator
HTR6
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HTR6
genes like me logo Genes that share disorders with HTR6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HTR6 Gene

Publications for HTR6 Gene

  1. Risperidone-related weight gain: genetic and nongenetic predictors. (PMID: 16633140) Lane H.Y. … Chang W.H. (J Clin Psychopharmacol 2006) 3 22 46 64
  2. No association of 5-HT2C, 5-HT6, and tryptophan hydroxylase-1 gene polymorphisms with personality traits in the Japanese population. (PMID: 16682118) Tochigi M. … Sasaki T. (Neurosci. Lett. 2006) 3 22 46 64
  3. Risperidone response and 5-HT6 receptor gene variance: genetic association analysis with adjustment for nongenetic confounders. (PMID: 14741325) Lane H.Y. … Chang W.H. (Schizophr. Res. 2004) 3 22 46 64
  4. Serotonergic genes and personality traits in the Korean population. (PMID: 14698468) Ham B.J. … Lee M.S. (Neurosci. Lett. 2004) 3 22 46 64
  5. Association of the HTR6 polymorphism C267T with late-onset Alzheimer's disease in Chinese. (PMID: 15531082) Kan R. … Wang L. (Neurosci. Lett. 2004) 3 22 46 64

Products for HTR6 Gene

  • Addgene plasmids for HTR6

Sources for HTR6 Gene

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