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Aliases for HTR5BP Gene

Aliases for HTR5BP Gene

  • 5-Hydroxytryptamine Receptor 5B, Pseudogene 2 3 5
  • 5-Hydroxytryptamine (Serotonin) Receptor 5B, Pseudogene 2 3
  • G Protein-Coupled Receptor 134 2 3
  • 5-Hydroxytryptamine (Serotonin) Receptor 5A Pseudogene 3
  • 5-Hydroxytryptamine (Serotonin) Receptor 5 Pseudogene 3
  • 5-Hydroxytryptamine (Serotonin) Receptor 5B 2
  • 5-HT5B 3
  • GPR134 3
  • HTR5B 3

External Ids for HTR5BP Gene

Previous HGNC Symbols for HTR5BP Gene

  • GPR134
  • HTR5B

Previous GeneCards Identifiers for HTR5BP Gene

  • GC02P118621

Summaries for HTR5BP Gene

GeneCards Summary for HTR5BP Gene

HTR5BP (5-Hydroxytryptamine Receptor 5B, Pseudogene) is a Pseudogene. Among its related pathways are Monoamine GPCRs.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HTR5BP Gene

Genomics for HTR5BP Gene

Regulatory Elements for HTR5BP Gene

Enhancers for HTR5BP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F117978 1.6 FANTOM5 Ensembl ENCODE 10.4 +121.4 121353 3.6 HDAC1 CBX3 TBL1XR1 RAD21 ZNF766 FOS CREM ZBTB11 NCOA1 CEBPB CCDC93 HTR5BP DDX18 GC02M117973 GC02M117974 LOC102723413
GH02F118084 1.5 FANTOM5 ENCODE 8.2 +228.4 228447 6.3 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 INSIG2 DDX18 CCDC93 HTR5BP RN7SL111P
GH02F117813 1.2 ENCODE 9.8 -44.2 -44222 3.5 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 DDX18 CCDC93 LOC102723413 HTR5BP GC02P117854
GH02F118054 1 Ensembl ENCODE 10.5 +196.5 196533 2.5 TBP PKNOX1 MXI1 TBL1XR1 SIN3A ASH2L BMI1 EED ZNF143 CREM HTR5BP CCDC93 DDX18 INSIG2 RN7SL111P
GH02F118049 0.9 Ensembl 10.5 +190.8 190774 1.2 PKNOX1 WRNIP1 BMI1 FEZF1 ZNF366 ZEB2 TBX21 ZNF843 IKZF1 GLIS1 CCDC93 HTR5BP INSIG2 RN7SL111P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HTR5BP on UCSC Golden Path with GeneCards custom track

Genomic Location for HTR5BP Gene

Chromosome:
2
Start:
117,859,427 bp from pter
End:
117,934,942 bp from pter
Size:
75,516 bases
Orientation:
Plus strand

Genomic View for HTR5BP Gene

Genes around HTR5BP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HTR5BP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HTR5BP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HTR5BP Gene

Proteins for HTR5BP Gene

Post-translational modifications for HTR5BP Gene

No Post-translational modifications

No data available for DME Specific Peptides for HTR5BP Gene

Domains & Families for HTR5BP Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HTR5BP: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HTR5BP Gene

Function for HTR5BP Gene

Animal Model Products

  • Taconic Biosciences Mouse Models for HTR5BP

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HTR5BP Gene

Localization for HTR5BP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HTR5BP Gene

Pathways & Interactions for HTR5BP Gene

SuperPathways for HTR5BP Gene

SuperPathway Contained pathways
1 Monoamine GPCRs
genes like me logo Genes that share pathways with HTR5BP: view

Pathways by source for HTR5BP Gene

1 BioSystems pathway for HTR5BP Gene

Interacting Proteins for HTR5BP Gene

Gene Ontology (GO) - Biological Process for HTR5BP Gene

None

No data available for SIGNOR curated interactions for HTR5BP Gene

Drugs & Compounds for HTR5BP Gene

(2) Drugs for HTR5BP Gene - From: IUPHAR and Tocris

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
[<sup>3</sup>H]5-CT Pharma Agonist 0
SB 699551 Pharma Antagonist Selective 5-ht5a antagonist 0

(1) Tocris Compounds for HTR5BP Gene

Compound Action Cas Number
SB 699551 Selective 5-ht5a antagonist 864741-95-7
genes like me logo Genes that share compounds with HTR5BP: view

Transcripts for HTR5BP Gene

mRNA/cDNA for HTR5BP Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for HTR5BP Gene

No ASD Table

Relevant External Links for HTR5BP Gene

GeneLoc Exon Structure for
HTR5BP
ECgene alternative splicing isoforms for
HTR5BP

Expression for HTR5BP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HTR5BP Gene

mRNA differential expression in normal tissues according to GTEx for HTR5BP Gene

This gene is overexpressed in Testis (x4.8).

NURSA nuclear receptor signaling pathways regulating expression of HTR5BP Gene:

HTR5BP
genes like me logo Genes that share expression patterns with HTR5BP: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for HTR5BP Gene

Orthologs for HTR5BP Gene

Evolution for HTR5BP Gene

ENSEMBL:
Gene Tree for HTR5BP (if available)
TreeFam:
Gene Tree for HTR5BP (if available)

No data available for Orthologs for HTR5BP Gene

Paralogs for HTR5BP Gene

No data available for Paralogs for HTR5BP Gene

Variants for HTR5BP Gene

Relevant External Links for HTR5BP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HTR5BP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for HTR5BP Gene

Disorders for HTR5BP Gene

No disorders were found for HTR5BP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for HTR5BP Gene

Publications for HTR5BP Gene

  1. Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. (PMID: 11343685) Grailhe R. … Hen R. (Eur. J. Pharmacol. 2001) 3 64

Products for HTR5BP Gene

Sources for HTR5BP Gene

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