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HTR3C Gene

protein-coding   GIFtS: 55
GCID: GC03P183770

5-Hydroxytryptamine (Serotonin) Receptor 3C, Ionotropic

(Previous names: 5-hydroxytryptamine (serotonin) receptor 3, family member...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
5-Hydroxytryptamine (Serotonin) Receptor 3C, Ionotropic1 2     5-HT3C2 3
5-Hydroxytryptamine (Serotonin) Receptor 3, Family Member C1 2     5-Hydroxytryptamine Receptor 3 Subunit C2
Serotonin Receptor 3C2 3     5-Hydroxytryptamine Receptor 3C2
5-HT3-C2 3     

External Ids:    HGNC: 240031   Entrez Gene: 1705722   Ensembl: ENSG000001780847   OMIM: 6101215   UniProtKB: Q8WXA83   

Export aliases for HTR3C gene to outside databases

Previous GC identifers: GC00U991163 GC03P184765 GC03P185172 GC03P185092 GC03P185093 GC03P185253 GC03P181178


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HTR3C Gene:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C
of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a
neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after
activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. (provided by RefSeq, Jul 2008)

GeneCards Summary for HTR3C Gene:
HTR3C (5-hydroxytryptamine (serotonin) receptor 3C, ionotropic) is a protein-coding gene. Diseases associated with HTR3C include sleep apnea, and major depressive disorder. GO annotations related to this gene include extracellular ligand-gated ion channel activity. An important paralog of this gene is HTR3E.

UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone
that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel,
which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively
nonselective, ion channel

summary for HTR3C Gene:
Serotonin 5-HT3 receptors, are ligand-gated ion channels of the Cys-loop family. The receptor consists of
4-transmembrane domains that form an intrinsic cation-selective channel. So far five human 5-HT3 receptor
subtypes have been identified (5-HT3A-E). The 5-HT3B-E subtypes do not form functional homo-oligomeric
complexes like the 5-HT3A subtypes, but co-assemble with 5-HT3A to influence its functional expression.

Gene Wiki entry for HTR3C Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the HTR3C gene promoter:
         p53   Sp1   RREB-1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   MEF-2A   AREB6   CP2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHTR3C promoter sequence
   Search Chromatin IP Primers for HTR3C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HTR3C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q27.1   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q27

HTR3C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HTR3C gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P183770:  view genomic region     (about GC identifiers)

Start:
183,770,835 bp from pter      End:
183,778,461 bp from pter
Size:
7,627 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8 (See protein sequence)
Recommended Name: 5-hydroxytryptamine receptor 3C precursor  
Size: 447 amino acids; 50220 Da
Subunit: Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex
Secondary accessions: A2RRR5

Explore the universe of human proteins at neXtProt for HTR3C: NX_Q8WXA8

Explore proteomics data for HTR3C at MOPED


See HTR3C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_570126.2  
ENSEMBL proteins: 
 ENSP00000322617  
Reactome Protein details: Q8WXA8

HTR3C Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
HTR: 5-HT (serotonin) receptors
HTR3: Ligand-gated ion channels / 5-HT (serotonin) receptors, ionotropic

IUPHAR Guide to PHARMACOLOGY protein family classification: 5-HT3C
5-HT3 receptors

5 InterPro protein domains:
 IPR027361 Acetylcholine_rcpt_TM
 IPR018000 Neurotransmitter_ion_chnl_CS
 IPR006201 Neur_channel
 IPR006202 Neur_chan_lig-bd
 IPR006029 Neurotrans-gated_channel_TM

Graphical View of Domain Structure for InterPro Entry Q8WXA8

ProtoNet protein and cluster: Q8WXA8

1 Blocks protein domain: IPB006201 Neurotransmitter-gated ion-channel

UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2)
subfamily. HTR3C sub-subfamily


HTR3C for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: 5HT3C_HUMAN, Q8WXA8
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone
that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel,
which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively
nonselective, ion channel

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005230extracellular ligand-gated ion channel activity IEA--
     
HTR3C for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HTR3C
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
5HT3C_HUMAN, Q8WXA8: Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic
reticulum unless complexed with HTR3A
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane5
endoplasmic reticulum1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0016020membrane ----
GO:0016021integral component of membrane IEA--

HTR3C for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for HTR3C About    
See pathways by source

SuperPathContained pathways About
1Ion channel transport
Ion channel transport0.58
2CREB Pathway
Intracellular Calcium Signaling0.50
3Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Transmembrane transport of small molecules0.47
4Circadian entrainment
Serotonergic synapse0.33
5Ligand-gated ion channel transport
Ligand-gated ion channel transport

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for HTR3C
    Intracellular Calcium Signaling

1 Reactome Pathway for HTR3C
    Ligand-gated ion channel transport


1 Kegg Pathway  (Kegg details for HTR3C):
    Serotonergic synapse


HTR3C for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HTR3C
Interactions:

    Search GeneGlobe Interaction Network for HTR3C

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5 Interacting proteins for HTR3C (ENSP000003226174) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
HTR3AENSP000003477544STRING: ENSP00000347754
HTR3BENSP000002601914STRING: ENSP00000260191
HTR3DENSP000004054094STRING: ENSP00000405409
HTR3EENSP000003355114STRING: ENSP00000335511
HDAC4ENSP000002646064STRING: ENSP00000264606
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006810transport ----
GO:0006811ion transport ----
GO:0034220ion transmembrane transport TAS--
GO:0055085transmembrane transport TAS--

HTR3C for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Compounds for HTR3C available from Tocris Bioscience    About this table
CompoundAction CAS #
Zacopride hydrochlorideHighly potent 5-HT3 receptor antagonist. Also 5-HT4 agonist[90182-92-6]
Ondansetron hydrochlorideSelective 5-HT3 antagonist[103639-04-9]
Granisetron hydrochloride5-HT3 antagonist[107007-99-8]
Tropisetron hydrochloridePotent 5-HT3 receptor antagonist; orally active[105826-92-4]
SR 57227 hydrochloride Potent, selective 5-HT3 agonist [77145-61-0]



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for HTR3C gene: 
NM_130770.2  

Unigene Cluster for HTR3C:

5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
Hs.632579  [show with all ESTs]
Unigene Representative Sequence: AF459285
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000318351(uc003fmk.3)
miRNA
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HTR3C
Primer
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OriGene qPCR primer pairs and template standards for HTR3C
OriGene qSTAR qPCR primer pairs in human, mouse for HTR3C
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat HTR3C
  QuantiTect SYBR Green Assays in human, mouse, rat HTR3C
  QuantiFast Probe-based Assays in human, mouse, rat HTR3C

Additional mRNA sequence: 

AF459285.1 BC131799.1 

1 DOTS entry:

DT.97807706 

3 AceView cDNA sequences:

NM_130770 AF459285 CD636081 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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HTR3C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
HTR3C Expression
About this image

HTR3C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

HTR3C Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.632579

UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
Tissue specificity: Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as
well as fetal colon and kidney

    Custom PCR Arrays for HTR3C
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HTR3C

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for HTR3C gene from Selected species (see all 6)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
dog
(Canis familiaris)
Mammalia HTR3C1 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 85.98(n)
81.21(a)
  607416  XM_844069.2  XP_849162.2 
zebrafish
(Danio rerio)
Actinopterygii CU207281.16
CABZ01016332.16
(see all 3)
Uncharacterized protein
(see all 3)
46(a)
32(a)
(see all 3)
many ↔ many
many ↔ many
(see all 3)
22(38280038-38282003) ENSDARG00000075094
22(38207011-38217520) ENSDARG00000053417


ENSEMBL Gene Tree for HTR3C (if available)
TreeFam Gene Tree for HTR3C (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for HTR3C gene
HTR3E2  HTR3A2  CHRNA102  CHRNA92  HTR3B2  ZACN2  CHRNA72  CHRFAM7A2  
HTR3D2  
4 SIMAP similar genes for HTR3C using alignment to 1 protein entry:     5HT3C_HUMAN:
HTR3E    HTR3D    HTR3A    HTR3B

HTR3C for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for HTR3C (see all 338)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0375524
A colorectal cancer sample4--see VAR_0375522 V M mis40--------
rs1844694351,2
--183634826(+) AGAACG/TATAAG 1 -- us2k10--------
rs119154921,2
C,F,H--183634831(+) tataaG/Acacat 1 -- us2k13Minor allele frequency- A:0.13NA WA 122
rs119154381,2
C,F,H--183634867(+) aattaC/Attttt 1 -- us2k1 tfbs34Minor allele frequency- A:0.13WA NA 124
rs119231481,2
C,A,H--183634873(+) tttttA/Ggccgg 1 -- us2k1 tfbs38Minor allele frequency- G:0.47WA NA CSA EA 367
rs1502221751,2
--183634877(+) TAGCCA/GGGTGC 1 -- us2k10--------
rs1889896331,2
--183634940(+) ACGACA/GTCAAG 1 -- us2k10--------
rs1809263421,2
--183634955(+) CAAGAC/TCATCC 1 -- us2k10--------
rs119155331,2
C,F,A,H--183634982(+) accccA/Gtctct 1 -- us2k11Minor allele frequency- G:0.00NA 2
rs1421958341,2
--183635015(+) GGGCGC/TGGTAG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for HTR3C (183770835 - 183778461 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for HTR3C:    About this table    
Variant IDTypeSubtypePubMed ID
nsv4145CNV Insertion18451855

Human Gene Mutation Database (HGMD): HTR3C
Locus Specific Mutation Databases (LSDB): HTR3C

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing HTR3C
DNA2.0 Custom Variant and Variant Library Synthesis for HTR3C

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610121    OMIM disorders: --

6 diseases for HTR3C:    
About MalaCards
sleep apnea    major depressive disorder    breast and colorectal cancer    schizophrenia
neuronitis    colorectal cancer


HTR3C for disorders           About GeneDecksing

Genetic Association Database (GAD): HTR3C
Human Genome Epidemiology (HuGE) Navigator: HTR3C (8 documents)

Export disorders for HTR3C gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for HTR3C gene, integrated from 10 sources (see all 16):
(articles sorted by number of sources associating them with HTR3C)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. (PubMed id 12801637)1, 2, 3 Niesler B.... Rappold G.A. (Gene 2003)
  2. Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy. (PubMed id 20021265)1, 4 Goecke T.W....Fasching P.A. (Acta Obstet Gynecol Scand 2010)
  3. A candidate gene study of obstructive sleep apnea in European Americans and African Americans. (PubMed id 20538960)1, 4 Larkin E.K....Redline S. (Am. J. Respir. Crit. Care Med. 2010)
  4. Allelic variants in HTR3C show association with autism. (PubMed id 19035560)1, 4 RehnstrAPm K....Peltonen L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
  5. Influence of 5-HT3 receptor subunit genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophrenia. (PubMed id 19794330)1, 4 Schuhmacher A....Maier W. (Pharmacogenet. Genomics 2009)
  6. Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy. (PubMed id 18681779)1, 4 Ward M.B....McKinnon R.A. (Pharmacogenomics 2008)
  7. Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. (PubMed id 18389280)1, 4 Fasching P.A....Strick R. (J. Cancer Res. Clin. Oncol. 2008)
  8. The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance. (PubMed id 15157181)1, 3 Peters J.A....Lambert J.J. (Biochem. Soc. Trans. 2004)
  9. A mega-analysis of genome-wide association studies for major depressive disorder. (PubMed id 22472876)1  ....Sullivan P.F. (Mol. Psychiatry 2013)
  10. Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. (PubMed id 21192076)1 Kapeller J....Niesler B. (J. Comp. Neurol. 2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 170572 HGNC: 24003 AceView: HTR3C Ensembl:ENSG00000178084 euGenes: HUgn170572
ECgene: HTR3C Kegg: 170572 H-InvDB: HTR3C

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for HTR3C Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for HTR3C gene:
Search GeneIP for patents involving HTR3C

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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