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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HTR3C Gene

protein-coding   GIFtS: 57
GCID: GC03P183770

5-Hydroxytryptamine (Serotonin) Receptor 3C, Ionotropic

(Previous names: 5-hydroxytryptamine (serotonin) receptor 3, family member...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
5-Hydroxytryptamine (Serotonin) Receptor 3C, Ionotropic1 2     5-HT3C2 3
5-Hydroxytryptamine (Serotonin) Receptor 3, Family Member C1 2     5-Hydroxytryptamine Receptor 3 Subunit C2
Serotonin Receptor 3C2 3     5-Hydroxytryptamine Receptor 3C2
5-HT3-C2 3     

External Ids:    HGNC: 240031   Entrez Gene: 1705722   Ensembl: ENSG000001780847   OMIM: 6101215   UniProtKB: Q8WXA83   

Export aliases for HTR3C gene to outside databases

Previous GC identifers: GC00U991163 GC03P184765 GC03P185172 GC03P185092 GC03P185093 GC03P185253 GC03P181178


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HTR3C Gene:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C
of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a
neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after
activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. (provided by RefSeq, Jul 2008)

GeneCards Summary for HTR3C Gene: 
HTR3C (5-hydroxytryptamine (serotonin) receptor 3C, ionotropic) is a protein-coding gene. Diseases associated with HTR3C include sleep apnea, and major depressive disorder, and among its related super-pathways are CREB Pathway and SLC-mediated transmembrane transport. GO annotations related to this gene include extracellular ligand-gated ion channel activity. An important paralog of this gene is HTR3E.

UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone
that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel,
which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively
nonselective, ion channel

summary for HTR3C Gene:
Serotonin 5-HT3 receptors, are ligand-gated ion channels of the Cys-loop family. The receptor consists of
4-transmembrane domains that form an intrinsic cation-selective channel. So far five human 5-HT3 receptor
subtypes have been identified (5-HT3A-E). The 5-HT3B-E subtypes do not form functional homo-oligomeric
complexes like the 5-HT3A subtypes, but co-assemble with 5-HT3A to influence its functional expression.

Gene Wiki entry for HTR3C Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HTR3C gene promoter:
         p53   Sp1   RREB-1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   MEF-2A   AREB6   CP2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHTR3C promoter sequence
   Search SABiosciences Chromatin IP Primers for HTR3C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HTR3C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q27.1   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q27

HTR3C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HTR3C gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P183770:  view genomic region     (about GC identifiers)

Start:
183,770,835 bp from pter      End:
183,778,461 bp from pter
Size:
7,627 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8 (See protein sequence)
Recommended Name: 5-hydroxytryptamine receptor 3C precursor  
Size: 447 amino acids; 50220 Da
Subunit: Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex
Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic
reticulum unless complexed with HTR3A
Secondary accessions: A2RRR5

Explore the universe of human proteins at neXtProt for HTR3C: NX_Q8WXA8

Explore proteomics data for HTR3C at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXA8

  • HTR3C Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HTR3C Protein Expression
    REFSEQ proteins: NP_570126.2  
    ENSEMBL proteins: 
     ENSP00000322617  
    Reactome Protein details: Q8WXA8
    Human Recombinant Protein Products for HTR3C: 
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    Cloud-Clone Corp. Proteins for HTR3C 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0045211postsynaptic membrane IEA--

    HTR3C for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HTR: 5-HT (serotonin) receptors
    HTR3: Ligand-gated ion channels / 5-HT (serotonin) receptors, ionotropic

    IUPHAR Guide to PHARMACOLOGY protein family classification: 5-HT3C 
    5-HT3 receptors

    5 InterPro protein domains:
     IPR027361 Acetylcholine_rcpt_TM
     IPR018000 Neurotransmitter_ion_chnl_CS
     IPR006201 Neur_channel
     IPR006202 Neur_chan_lig-bd
     IPR006029 Neurotrans-gated_channel_TM

    Graphical View of Domain Structure for InterPro Entry Q8WXA8

    ProtoNet protein and cluster: Q8WXA8

    1 Blocks protein domain: IPB006201 Neurotransmitter-gated ion-channel

    UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
    Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2)
    subfamily. HTR3C sub-subfamily


    HTR3C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: 5HT3C_HUMAN, Q8WXA8
    Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone
    that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel,
    which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively
    nonselective, ion channel

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005230extracellular ligand-gated ion channel activity IEA--
         
    HTR3C for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HTR3C About                                                                                                See pathways by source

    SuperPathContained pathways About
    1CREB Pathway
    Intracellular Calcium Signaling0.50
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50
    3Ion channel transport
    Ion channel transport0.49
    4GABA A receptor activation
    Ligand-gated ion channel transport0.48
    5Circadian entrainment
    Serotonergic synapse0.33

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for HTR3C
        Intracellular Calcium Signaling

    3        Reactome Pathways for HTR3C
        Ligand-gated ion channel transport
    Transmembrane transport of small molecules
    Ion channel transport


    1         Kegg Pathway  (Kegg details for HTR3C):
        Serotonergic synapse


    HTR3C for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HTR3C

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for HTR3C (ENSP000003226174) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HTR3AENSP000003477544STRING: ENSP00000347754
    HTR3BENSP000002601914STRING: ENSP00000260191
    HTR3DENSP000004054094STRING: ENSP00000405409
    HTR3EENSP000003355114STRING: ENSP00000335511
    HDAC4ENSP000002646064STRING: ENSP00000264606
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006811ion transport ----
    GO:0034220ion transmembrane transport TAS--
    GO:0055085transmembrane transport TAS--

    HTR3C for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for HTR3C available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Zacopride hydrochlorideHighly potent 5-HT3 receptor antagonist. Also 5-HT4 agonist[90182-92-6]
    Ondansetron hydrochlorideSelective 5-HT3 antagonist[103639-04-9]
    Granisetron hydrochloride5-HT3 antagonist[107007-99-8]
    Tropisetron hydrochloridePotent 5-HT3 receptor antagonist; orally active[105826-92-4]
    SR 57227 hydrochloride Potent, selective 5-HT3 agonist [77145-61-0]

    Search CenterWatch for drugs/clinical trials and news about HTR3C / 5HT3C

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HTR3C gene: 
    NM_130770.2  

    Unigene Cluster for HTR3C:

    5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
    Hs.632579  [show with all ESTs]
    Unigene Representative Sequence: AF459285
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000318351(uc003fmk.3)
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HTR3C
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HTR3C

    Additional mRNA sequence: 

    AF459285.1 BC131799.1 

    1 DOTS entry:

    DT.97807706 

    3 AceView cDNA sequences:

    NM_130770 AF459285 CD636081 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HTR3C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HTR3C Expression
    About this image


    See HTR3C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HTR3C

    SOURCE GeneReport for Unigene cluster: Hs.632579

    UniProtKB/Swiss-Prot: 5HT3C_HUMAN, Q8WXA8
    Tissue specificity: Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as
    well as fetal colon and kidney

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HTR3C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for HTR3C gene from 5/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia LOC4881011 5-hydroxytryptamine receptor 3C-like 82.03(n)
    78.75(a)
      488101  XM_545225.3  XP_545225.3 
    chicken
    (Gallus gallus)
    Aves --
    --
    22(a)
    possible ortholog
    18(10892021-10897084)
    zebrafish
    (Danio rerio)
    Actinopterygii CU207281.16
    AL954343.26
    (see all 7)
    Uncharacterized protein
    (see all 7)
    47(a)
    34(a)
    (see all 7)
    many ↔ many
    possible ortholog
    (see all 7)
    22(38280038-38282003)
    3(58826656-58827462)
    fruit fly
    (Drosophila melanogaster)
    Insecta nAcRbeta-21C6
    nicotinic acetylcholine receptor beta 21C
    16(a)
    1 → many
    2L(545129-547096)
    worm
    (Caenorhabditis elegans)
    Secernentea lgc-116
    lgc-56
    (see all 29)
    Protein LGC-5
    (see all 29)
    19(a)
    19(a)
    (see all 29)
    many ↔ many
    many ↔ many
    (see all 29)
    X(7503823-7506633)
    IV(8342672-8344122)


    ENSEMBL Gene Tree for HTR3C (if available)
    TreeFam Gene Tree for HTR3C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HTR3C gene
    HTR3E2  HTR3A2  HTR3D2  HTR3B2  ZACN2  
    4 SIMAP similar genes for HTR3C using alignment to 1 protein entry:     5HT3C_HUMAN:
    HTR3E    HTR3D    HTR3A    HTR3B

    HTR3C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/338 SNPs in HTR3C are shown (see all 338)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0375524
    A colorectal cancer sample4--see VAR_0375522 V M mis40--------
    rs1844694351,2
    --183634826(+) AGAACG/TATAAG 1 -- us2k10--------
    rs119154921,2
    C,F,H--183634831(+) tataaG/Acacat 1 -- us2k13Minor allele frequency- A:0.13NA WA 122
    rs119154381,2
    C,F,H--183634867(+) aattaC/Attttt 1 -- us2k1 tfbs34Minor allele frequency- A:0.13WA NA 124
    rs119231481,2
    C,A,H--183634873(+) tttttA/Ggccgg 1 -- us2k1 tfbs38Minor allele frequency- G:0.47WA NA CSA EA 367
    rs1502221751,2
    --183634877(+) TAGCCA/GGGTGC 1 -- us2k10--------
    rs1889896331,2
    --183634940(+) ACGACA/GTCAAG 1 -- us2k10--------
    rs1809263421,2
    --183634955(+) CAAGAC/TCATCC 1 -- us2k10--------
    rs119155331,2
    C,F,A,H--183634982(+) accccA/Gtctct 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs1421958341,2
    --183635015(+) GGGCGC/TGGTAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HTR3C (183770835 - 183778461 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for HTR3C:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4145CNV Insertion18451855


    Human Gene Mutation Database (HGMD): HTR3C

    Locus Specific Mutation Databases (LSDB): HTR3C
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610121    OMIM disorders: --

    4 diseases for HTR3C:    About MalaCards
    sleep apnea    major depressive disorder    schizophrenia    neuronitis


    HTR3C for disorders           About GeneDecksing

    Genetic Association Database (GAD): HTR3C
    Human Genome Epidemiology (HuGE) Navigator: HTR3C (8 documents)

    Export disorders for HTR3C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HTR3C gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with HTR3C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. (PubMed id 12801637)1, 2, 3 Niesler B.... Rappold G.A. (2003)
    2. Two naturally occurring variants of the serotonin rec eptor gene HTR3C are associated with nausea in pregnancy. (PubMed id 20021265)1, 4 Goecke T.W....Fasching P.A. (2010)
    3. A candidate gene study of obstructive sleep apnea in European Americans and African Americans. (PubMed id 20538960)1, 4 Larkin E.K....Redline S. (2010)
    4. Allelic variants in HTR3C show association with autis m. (PubMed id 19035560)1, 4 RehnstrAPm K....Peltonen L. (2009)
    5. Influence of 5-HT3 receptor subunit genes HTR3A, HTR3 B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophre nia. (PubMed id 19794330)1, 4 Schuhmacher A....Maier W. (2009)
    6. Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy. (PubMed id 18681779)1, 4 Ward M.B....McKinnon R.A. (2008)
    7. Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. (PubMed id 18389280)1, 4 Fasching P.A....Strick R. (2008)
    8. The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance. (PubMed id 15157181)1, 3 Peters J.A....Lambert J.J. (2004)
    9. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    10. A mega-analysis of genome-wide association studies for major depressive disorder. (PubMed id 22472876)1 (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 170572 HGNC: 24003 AceView: HTR3C Ensembl:ENSG00000178084 euGenes: HUgn170572
    ECgene: HTR3C Kegg: 170572 H-InvDB: HTR3C

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HTR3C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HTR3C gene:
    Search GeneIP for patents involving HTR3C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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