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Aliases for HTR2C Gene

Aliases for HTR2C Gene

  • 5-Hydroxytryptamine Receptor 2C 2 3 5
  • 5-Hydroxytryptamine (Serotonin) Receptor 2C, G Protein-Coupled 2 3
  • 5-Hydroxytryptamine Receptor 1C 3 4
  • 5-HTR2C 3 4
  • 5-HT1C 3 4
  • 5-HT2C 3 4
  • HTR1C 3 4
  • 5-Hydroxytryptamine (Serotonin) Receptor 2C 2
  • Serotonin 5-HT-1C Receptor 3
  • Serotonin 5-HT-2C Receptor 3
  • Serotonin Receptor 2C 4
  • 5-HT-1C 4
  • 5-HT-2C 4
  • 5HTR2C 3

External Ids for HTR2C Gene

Previous HGNC Symbols for HTR2C Gene

  • HTR1C

Previous GeneCards Identifiers for HTR2C Gene

  • GC0XP108837
  • GC0XP110943
  • GC0XP111854
  • GC0XP112582
  • GC0XP113641
  • GC0XP113818
  • GC0XP103403

Summaries for HTR2C Gene

Entrez Gene Summary for HTR2C Gene

  • This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]

GeneCards Summary for HTR2C Gene

HTR2C (5-Hydroxytryptamine Receptor 2C) is a Protein Coding gene. Diseases associated with HTR2C include Htr2c-Related Altered Drug Metabolism and Premature Ejaculation. Among its related pathways are Signaling by GPCR and Serotonin Receptor 2 and ELK-SRF/GATA4 signaling. GO annotations related to this gene include G-protein coupled receptor activity and G-protein coupled serotonin receptor activity. An important paralog of this gene is HTR2A.

UniProtKB/Swiss-Prot for HTR2C Gene

  • G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

Tocris Summary for HTR2C Gene

  • Serotonin 5-HT2C receptors, previously known as 5-HT1C receptors, are located primarily in the choroid plexus, cortex, limbic system and basal ganglia. 5-HT2C receptors play a role in CSF volume regulation, thermoregulation, penile erection and anxiety.

Gene Wiki entry for HTR2C Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HTR2C Gene

Genomics for HTR2C Gene

Regulatory Elements for HTR2C Gene

Enhancers for HTR2C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF114584 1 Ensembl ENCODE 0.8 +0.7 723 0.4 ZNF146 POLR2A EZH2 HTR2C RPL36AP53
GH0XF114583 0.5 ENCODE 0.8 -0.1 -76 0.2 POLR2A MAX HTR2C GC0XM114472
GH0XF114527 0.4 FANTOM5 0.2 -56.8 -56761 0.2 GC0XM114472 HTR2C
GH0XF114472 1.2 Ensembl ENCODE 0.1 -111.3 -111343 1.3 POLR2A TEAD4 GC0XM114472 HTR2C
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around HTR2C on UCSC Golden Path with GeneCards custom track

Genomic Location for HTR2C Gene

Chromosome:
X
Start:
114,584,078 bp from pter
End:
114,910,061 bp from pter
Size:
325,984 bases
Orientation:
Plus strand

Genomic View for HTR2C Gene

Genes around HTR2C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HTR2C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HTR2C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HTR2C Gene

Proteins for HTR2C Gene

  • Protein details for HTR2C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P28335-5HT2C_HUMAN
    Recommended name:
    5-hydroxytryptamine receptor 2C
    Protein Accession:
    P28335
    Secondary Accessions:
    • B1AMW4
    • Q5VUF8
    • Q9NP28

    Protein attributes for HTR2C Gene

    Size:
    458 amino acids
    Molecular mass:
    51821 Da
    Quaternary structure:
    • Interacts with MPDZ. Interacts with ARRB2.

    Alternative splice isoforms for HTR2C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for HTR2C Gene

Post-translational modifications for HTR2C Gene

Other Protein References for HTR2C Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for HTR2C

No data available for DME Specific Peptides for HTR2C Gene

Domains & Families for HTR2C Gene

Graphical View of Domain Structure for InterPro Entry

P28335

UniProtKB/Swiss-Prot:

5HT2C_HUMAN :
  • The PDZ domain-binding motif is involved in the interaction with MPDZ.
  • Belongs to the G-protein coupled receptor 1 family.
Domain:
  • The PDZ domain-binding motif is involved in the interaction with MPDZ.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with HTR2C: view

Function for HTR2C Gene

Molecular function for HTR2C Gene

GENATLAS Biochemistry:
5-hydroxytryptamine (serotonin) receptor,subtype 2C with two alternatively spliced forms,G protein coupled receptor superfamily,activating the phosphatidylinositol cycle
UniProtKB/Swiss-Prot Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

Gene Ontology (GO) - Molecular Function for HTR2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001587 Gq/11-coupled serotonin receptor activity IDA 18703043
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004993 G-protein coupled serotonin receptor activity IDA 7582481
GO:0008144 drug binding IDA 12970106
genes like me logo Genes that share ontologies with HTR2C: view
genes like me logo Genes that share phenotypes with HTR2C: view

Animal Models for HTR2C Gene

MGI Knock Outs for HTR2C:

Animal Model Products

  • Taconic Biosciences Mouse Models for HTR2C

miRNA for HTR2C Gene

miRTarBase miRNAs that target HTR2C

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR2C

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HTR2C Gene

Localization for HTR2C Gene

Subcellular locations from UniProtKB/Swiss-Prot for HTR2C Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HTR2C Gene COMPARTMENTS Subcellular localization image for HTR2C gene
Compartment Confidence
plasma membrane 5
cytosol 2
extracellular 2
nucleus 2

Gene Ontology (GO) - Cellular Components for HTR2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IMP 18703043
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030425 dendrite IBA --
genes like me logo Genes that share ontologies with HTR2C: view

Pathways & Interactions for HTR2C Gene

genes like me logo Genes that share pathways with HTR2C: view

Gene Ontology (GO) - Biological Process for HTR2C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001662 behavioral fear response ISS --
GO:0006182 cGMP biosynthetic process IDA 12970106
GO:0006874 cellular calcium ion homeostasis IDA 19057895
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with HTR2C: view

No data available for SIGNOR curated interactions for HTR2C Gene

Drugs & Compounds for HTR2C Gene

(191) Drugs for HTR2C Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Agomelatine Approved, Investigational Pharma Antagonist, agonist, Target, antagonist MT1/MT2 / 5-HT2C agonist 0
Olanzapine Approved, Investigational Pharma Antagonist, agonist, Target, antagonist 395
Ziprasidone Approved Pharma Antagonist, agonist, Target, antagonist 5-HT (serotonin)/dopamine receptor antagonist 145
Risperidone Approved, Investigational Pharma Antagonist, antagonist, Target SR-2A inhibitor 487
Mianserin Approved Pharma Antagonist, antagonist, Target 51

(24) Additional Compounds for HTR2C Gene - From: IUPHAR, Novoseek, and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
<i>m</i>-CPP
Antagonist
5-HT
Full agonist, Agonist
alpha-methyl-5-HT
Full agonist, Agonist
DOB
Full agonist, Agonist
MDL-100,907
Antagonist

(5) Tocris Compounds for HTR2C Gene

Compound Action Cas Number
CP 809101 hydrochloride Potent and selective 5-HT2C agonist 1215721-40-6
N-Desmethylclozapine 5-HT2C antagonist 6104-71-8
Ro 60-0175 fumarate Potent, selective 5-HT2C agonist 169675-09-6
SB 206553 hydrochloride Potent, selective 5-HT2C/5-HT2B antagonist. Orally active 1197334-04-5
SB 242084 Selective 5-HT2C antagonist; brain penetrant 1215566-78-1

(39) ApexBio Compounds for HTR2C Gene

Compound Action Cas Number
1-Methylpsilocin 1465-16-3
Agomelatine MT1/MT2 / 5-HT2C agonist 138112-76-2
Agomelatine hydrochloride 1176316-99-6
Agomelatine L(+)-Tartaric acid 824393-18-2
Amperozide hydrochloride
Cinanserin hydrochloride 54-84-2
CP-809101 5-HT2C receptor agonist 479683-64-2
CP-809101 hydrochloride 5-HT2C receptor agonist, potent and selective 1215721-40-6
Cyclobenzaprine HCl 5-HT2 receptor antagonist 6202-23-9
DV 7028 hydrochloride 133364-62-2
EMD 281014 hydrochloride 443144-27-2
Lamotrigine 5-HT inhibitor 84057-84-1
LY 215840 137328-52-0
MDL 72222 40796-97-2
Mesulergine hydrochloride 72786-12-0
Metergoline 17692-51-2
Methiothepin maleate 19728-88-2
Methylergometrine maleate 57432-61-8
Mianserin HCl 5-HT2 receptor antagonist 21535-47-7
Mirtazapine 85650-52-8
MK 212 hydrochloride 61655-58-1
N-Desmethylclozapine 6104-71-8
Org 12962 hydrochloride 210821-63-9
Org 37684 213007-95-5
PNU 22394 hydrochloride 15923-42-9
PRX-08066 Maleic acid 5-HT2B receptor antagonist,potent and selective 866206-55-5
Ritanserin 87051-43-2
Ro 60-0175 fumarate 169675-09-6
RS 127445 5-HT2B receptor antagonist,high affinity 199864-87-4
S 32212 hydrochloride 847871-78-7
SB 206553 hydrochloride 1197334-04-5
SB 221284 196965-14-7
SB 228357 181629-93-6
SDZ SER 082 fumarate 1417343-80-6
Sumatriptan Succinate 5-HT1 receptor agonist 103628-48-4
WAY 161503 hydrochloride 276695-22-8
WAY 629 hydrochloride 57756-44-2
Ziprasidone 5-HT (serotonin)/dopamine receptor antagonist 146939-27-7
α-Methyl-5-hydroxytryptamine maleate 97469-12-0
genes like me logo Genes that share compounds with HTR2C: view

Drug Products

Transcripts for HTR2C Gene

mRNA/cDNA for HTR2C Gene

Unigene Clusters for HTR2C Gene

5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR2C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HTR2C Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1:
SP2: -

Relevant External Links for HTR2C Gene

GeneLoc Exon Structure for
HTR2C
ECgene alternative splicing isoforms for
HTR2C

Expression for HTR2C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HTR2C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HTR2C Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x16.9), Brain - Putamen (basal ganglia) (x10.0), Brain - Caudate (basal ganglia) (x8.7), and Brain - Hypothalamus (x7.5).

Protein differential expression in normal tissues from HIPED for HTR2C Gene

This gene is overexpressed in Plasma (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HTR2C Gene



Protein tissue co-expression partners for HTR2C Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of HTR2C Gene:

HTR2C

SOURCE GeneReport for Unigene cluster for HTR2C Gene:

Hs.149037

mRNA Expression by UniProt/SwissProt for HTR2C Gene:

P28335-5HT2C_HUMAN
Tissue specificity: Detected in brain.
genes like me logo Genes that share expression patterns with HTR2C: view

Primer Products

Orthologs for HTR2C Gene

This gene was present in the common ancestor of animals.

Orthologs for HTR2C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HTR2C 34 35
  • 99.71 (n)
cow
(Bos Taurus)
Mammalia HTR2C 34
  • 90.62 (n)
dog
(Canis familiaris)
Mammalia HTR2C 34 35
  • 90.47 (n)
rat
(Rattus norvegicus)
Mammalia Htr2c 34
  • 86.65 (n)
mouse
(Mus musculus)
Mammalia Htr2c 34 16 35
  • 86.29 (n)
oppossum
(Monodelphis domestica)
Mammalia HTR2C 35
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves HTR2C 35
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia HTR2C 35
  • 57 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii htr2cl2 35
  • 53 (a)
OneToMany
htr2cl1 35
  • 47 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta GPR5HT2A 34
  • 49.74 (n)
fruit fly
(Drosophila melanogaster)
Insecta 5-HT2 36 35
  • 44 (a)
TyrRII 35
  • 19 (a)
ManyToMany
5-HT1B 35
  • 17 (a)
ManyToMany
TyrR 35
  • 17 (a)
ManyToMany
CG42796 35
  • 15 (a)
ManyToMany
5-HT1A 35
  • 13 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea M03F4.3 36
  • 41 (a)
sca-1 36
  • 31 (a)
ser-1 36 35
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 22 (a)
OneToMany
Species where no ortholog for HTR2C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for HTR2C Gene

ENSEMBL:
Gene Tree for HTR2C (if available)
TreeFam:
Gene Tree for HTR2C (if available)

Paralogs for HTR2C Gene

Paralogs for HTR2C Gene

genes like me logo Genes that share paralogs with HTR2C: view

Variants for HTR2C Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for HTR2C Gene

5HT2C_HUMAN-P28335
Position 23 is polymorphic; the frequencies in unrelated Caucasians are 0.87 for Cys and 0.13 for Ser.

Sequence variations from dbSNP and Humsavar for HTR2C Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1414334 drug-response 114,903,581(+) ACCCT(C/G)TCTTG intron-variant
rs3813929 drug-response 114,584,047(+) CATCC(C/T)GCTTT upstream-variant-2KB
rs193920954 Uncertain significance 114,848,155(+) ATTCG(C/T)GGACT intron-variant, reference, missense
rs6318 Benign 114,731,326(+) GCAAT(C/G)TGATA intron-variant, reference, missense
rs10127225 -- 114,759,803(+) CACTT(C/T)GTGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for HTR2C Gene

Variant ID Type Subtype PubMed ID
dgv4277n106 CNV duplication 24896259
dgv523n21 CNV loss 19592680
dgv524n21 CNV gain 19592680
esv1117381 CNV deletion 17803354
esv1501559 CNV insertion 17803354
esv2660156 CNV deletion 23128226
esv2740401 CNV deletion 23290073
esv3305724 CNV mobile element insertion 20981092
esv3342375 CNV insertion 20981092
esv33994 CNV gain+loss 17666407
esv3574320 CNV loss 25503493
esv3574321 CNV loss 25503493
nsv1110834 CNV insertion 24896259
nsv1115280 CNV deletion 24896259
nsv1128548 CNV deletion 24896259
nsv1150985 CNV duplication 26484159
nsv507990 OTHER sequence alteration 20534489
nsv527347 CNV gain 19592680
nsv7044 CNV deletion 18451855

Variation tolerance for HTR2C Gene

Residual Variation Intolerance Score: 62.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.42; 71.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HTR2C Gene

Human Gene Mutation Database (HGMD)
HTR2C
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HTR2C

Disorders for HTR2C Gene

MalaCards: The human disease database

(22) MalaCards diseases for HTR2C Gene - From: GeneTests, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
htr2c-related altered drug metabolism
  • serotonin 5-ht-2c receptor
premature ejaculation
borderline personality disorder
migraine with aura
  • classic migraine
psychosexual disorder
  • psychosexual disorders
- elite association - COSMIC cancer census association via MalaCards
Search HTR2C in MalaCards View complete list of genes associated with diseases

Relevant External Links for HTR2C

Genetic Association Database (GAD)
HTR2C
Human Genome Epidemiology (HuGE) Navigator
HTR2C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HTR2C
genes like me logo Genes that share disorders with HTR2C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HTR2C Gene

Publications for HTR2C Gene

  1. A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome. (PMID: 20010450) Dehning S. … Zill P. (Psychiatr. Genet. 2010) 3 22 46 64
  2. Comorbidity between bipolar disorder and alcohol use disorder: association of dopamine and serotonin gene polymorphisms. (PMID: 20071033) Yasseen B. … Busto U.E. (Psychiatry Res 2010) 3 22 46 64
  3. Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample. (PMID: 20504252) Opgen-Rhein C. … Dettling M. (Pharmacogenomics 2010) 3 22 46 64
  4. Fluoxetine response in impulsive-aggressive behavior and serotonin transporter polymorphism in personality disorder. (PMID: 20010449) Silva H. … Bustamante M.L. (Psychiatr. Genet. 2010) 3 22 46 64
  5. Mutation screening and assessment of the effect of genetic variations on expression and RNA editing of serotonin receptor 2C in the human brain. (PMID: 20015120) Bundo M. … Kato T. (Psychiatry Clin. Neurosci. 2010) 3 22 46 64

Products for HTR2C Gene

Sources for HTR2C Gene

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