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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HTR1E Gene

protein-coding   GIFtS: 64
GCID: GC06P087647

5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled

(Previous name: 5-hydroxytryptamine (serotonin) receptor 1E )
 Explore 9 diseases affiliated with
HTR1E via our new
 Human Malady Compendium 
Biological research products
for HTR1E
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
5-Hydroxytryptamine (Serotonin) Receptor 1E, G Protein-Coupled1 2     S312 3
5-HT1E1 2 3     5-Hydroxytryptamine (Serotonin) Receptor 1E1
Serotonin Receptor 1E2 3     5-Hydroxytryptamine Receptor 1E2
5-HT-1E2 3     

External Ids:    HGNC: 52911   Entrez Gene: 33542   Ensembl: ENSG000001688307   OMIM: 1821325   UniProtKB: P285663   

Export aliases for HTR1E gene to outside databases

Previous GC identifers: GC06P087593 GC06P087643 GC06P087704 GC06P084863


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: 5HT1E_HUMAN, P28566
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that
functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins
that inhibit adenylate cyclase activity

summary for HTR1E:
Serotonin 5-ht1E receptors are primarily located in the cortex, caudate putamen, claustrum, hippocampus, and
amygdala. The human 5-ht1E receptor gene has been localized to chromosome 6 (6q14-q15). The function of this
receptor has yet to be elucidated.

Gene Wiki entry for HTR1E (5-HT1E receptor)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007299.13  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for HTR1E
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHTR1E promoter sequence
   Search SABiosciences Chromatin IP Primers for HTR1E

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HTR1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14-q15   Ensembl cytogenetic band:  6q14.3   HGNC cytogenetic band: 6q14-q15

HTR1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HTR1E gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P087647:  view genomic region     (about GC identifiers)

Start:
87,647,024 bp from pter      End:
87,726,401 bp from pter
Size:
79,378 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: 5HT1E_HUMAN, P28566 (See protein sequence)
Recommended Name: 5-hydroxytryptamine receptor 1E  
Size: 365 amino acids; 41682 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: E1P503 Q9P1Y1

Explore the universe of human proteins at neXtProt for HTR1E: NX_P28566

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P28566

  • HTR1E Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_000856.1  
    ENSEMBL proteins: 
     ENSP00000358597   ENSP00000307766  
    Reactome Protein details: P28566
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    Uscn Proteins for HTR1E

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS1733778


    HTR1E for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    HTR1E for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002231 5HT_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry P28566

    ProtoNet protein and cluster: P28566

    1 Blocks protein family: IPB002231 5-hydroxytryptamine receptor signature

    UniProtKB/Swiss-Prot: 5HT1E_HUMAN, P28566
    Similarity: Belongs to the G-protein coupled receptor 1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: 5HT1E_HUMAN, P28566
    Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that
    functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins
    that inhibit adenylate cyclase activity

         Genatlas biochemistry entry for HTR1E:
    5-hydroxytryptamine (serotonin) receptor,subtype IE,G protein coupled receptor superfamily,inhibiting adenylate cyclase

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    hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7e hsa-let-7g hsa-miR-3927 hsa-let-7b
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity TAS1733778
    GO:0004993serotonin receptor activity IDA1608964
    GO:0051378serotonin binding IDA1608964


    HTR1E for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)1.00
    GPCRs, Class A Rhodopsin-like0.41
    GPCR ligand binding0.75
    Neuroactive ligand-receptor interaction0.38
    G alpha (i) signalling events0.44
    2Monoamine GPCRs
    Monoamine GPCRs1.00
    Serotonin receptors0.36
    Amine ligand-binding receptors0.79
    Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics0.20
    3Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    GPCR downstream signaling0.89
    4CREB Pathway
    Intracellular Calcium Signaling0.50

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for HTR1E
        Intracellular Calcium Signaling

    2 BioSystems Pathways for HTR1E 
        GPCRs, Class A Rhodopsin-like
    Monoamine GPCRs

    5/8        Reactome Pathways for HTR1E (see all 8)
        GPCR downstream signaling
    Signaling by GPCR
    GPCR ligand binding
    Class A/1 (Rhodopsin-like receptors)
    Serotonin receptors

    1 PharmGKB Pathway for HTR1E
        Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics

    1         Kegg Pathway  (Kegg details for HTR1E):
        Neuroactive ligand-receptor interaction


    HTR1E for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HTR1E

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/145 Interacting proteins for HTR1E (P285663 ENSP000003077664) via UniProtKB, MINT, STRING, and/or I2D (see all 145)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PSMC3P179803, ENSP000002988524I2D: score=2 STRING: ENSP00000298852
    PSMC4P436863, ENSP000001578124I2D: score=2 STRING: ENSP00000157812
    ADCY2ENSP000003429524STRING: ENSP00000342952
    ADRA2BENSP000003872814STRING: ENSP00000387281
    DRD2ENSP000003548594STRING: ENSP00000354859
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS1608964
    GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS1733778
    GO:0007210serotonin receptor signaling pathway IDA1608964
    GO:0007268synaptic transmission TAS1608964


    HTR1E for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    HTR1E for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for HTR1E available from Tocris Bioscience    About this table
    CompoundAction CAS #
    BRL 54443Potent 5-ht1E/F agonist[57477-39-1]

    1 HMDB Compound for HTR1E    About this table
    CompoundSynonyms CAS #PubMed Ids
    Serotonin3-(2-Aminoethyl)-1H-indol-5-ol (see all 14)50-67-9--

    6 DrugBank Compounds for HTR1E    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Eletriptan-- 143322-58-1targetagonist17139284 17016423
    AripiprazoleOPC 31 (see all 2)129722-12-9targetantagonist17848919
    Clozapine-- 5786-21-0targetantagonist17848919
    Olanzapine-- 132539-06-1targetantagonist17848919
    QuetiapineQuetiapine fumarate (see all 2)111974-69-7targetother/unknown17848919
    ZiprasidoneZiprasidone hydrochloride (see all 2)146939-27-7targetantagonist17848919

    6 Novoseek chemical compound relationships for HTR1E gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-carboxamidotryptamine 83.8 1 1513320 (1)
    5-hydroxytryptamine 76.5 4 8883928 (1), 1513320 (1)
    methysergide 75.6 1 1513320 (1)
    ergotamine 75 1 1513320 (1)
    guanine 46.8 1 8450834 (1)
    oligonucleotide 29.1 1 9316030 (1)

    Search CenterWatch for drugs/clinical trials and news about HTR1E / 5HT1E 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HTR1E gene: 
    NM_000865.2  

    Unigene Cluster for HTR1E:

    5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
    Hs.1611  [show with all ESTs]
    Unigene Representative Sequence: NM_000865
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369584 ENST00000305344(uc003pli.3)

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    hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7e hsa-let-7g hsa-miR-3927 hsa-let-7b
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    Additional cDNA sequence: 

    AF498980.1 BC069751.1 M91467.1 

    3 DOTS entries:

    DT.91739998  DT.100670613  DT.100661910 

    24/25 AceView cDNA sequences (see all 25):

    CR618239 CR606192 BC069751 CR596923 AF498980 BX349901 AL561877 AL561841 
    BX389401 M91467 CB565887 AL521494 AL520002 AL520435 NM_000865 BX355486 
    AL522462 AL521170 AL522463 AL519220 AI807334 AL521493 AI479667 AL521169 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HTR1E expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGTGGATGGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See HTR1E Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HTR1E

    SOURCE GeneReport for Unigene cluster: Hs.1611
        SABiosciences Expression via Pathway-Focused PCR Array including HTR1E: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HTR1E

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for HTR1E gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves HTR1E1 5-hydroxytryptamine (serotonin) receptor 1E 75.73(n)
    86.81(a)
      771973  XM_001235178.1  XP_001235179.1 
    lizard
    (Anolis carolinensis)
    Reptilia HTR1E6
    --
    82(a)
    1 ↔ 1
    1(176521736-176522830)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.221722 Xenopus laevis transcribed sequence with moderate similarity more 72.19(n)    48025952 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003306811 5-hydroxytryptamine receptor 1E-like 65.93(n)
    68.14(a)
      100330681  XM_002665643.1  XP_002665689.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta 5-HT1A3 serotonin receptor signaling pathway
    G-protein more
    43(a)
    (best of 3)
        --
    worm
    (Caenorhabditis elegans)
    Secernentea M03F4.33 G-protein coupled receptor 37(a)   X(4985611-4990413)   --


    ENSEMBL Gene Tree for HTR1E (if available)
    TreeFam Gene Tree for HTR1E (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HTR1E gene
    DRD42  HTR1A2  ADRA1B2  DRD22  HTR1F2  HTR72  ADRA2C2  ADRA2A2  
    HTR1D2  ADRA1A2  ADRA2B2  DRD32  HTR5A2  HTR1B2  ADRA1D2  
    18 SIMAP similar genes for HTR1E using alignment to 1 protein entry:     5HT1E_HUMAN:
    HTR1F    HTR1D    HTR1B    5HT1A    HTR1A    HTR5A
    ADRA1D    HTR7    HTR2C    ADRA1A    HTR2A    ADRA1B
    DRD3    ADRB1    DRD1    HRH2    ADRB2    ADRA2A

    HTR1E for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1323 NCBI SNPs in HTR1E are shown (see all 1323    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1420013311,2
    C,other87725851(+) TCCCCA/C/TCCTTC 3 T P S mis10--------
    rs1134630671,2
    --87645033(+) AAGTTT/GCCCCA 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1181253731,2
    F,--87645148(+) TGATGA/TCTTTT 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs1486217051,2
    --87645189(+) CCTTAC/TAGTTT 1 -- us2k10--------
    rs753834571,2
    F,--87645345(+) TTATTA/GAAACT 1 -- us2k11Minor allele frequency- G:0.04NA 120
    rs1420582151,2
    --87645362(+) ATATAC/TGCCAG 1 -- us2k10--------
    rs1511306071,2
    --87645430(+) AAAGCA/GGGTAT 1 -- us2k10--------
    rs1916207781,2
    --87645435(+) GGGTAC/TTCTGA 1 -- us2k10--------
    rs1406117691,2
    --87645490(+) AGTTCC/TTTATG 1 -- us2k10--------
    rs1843967581,2
    --87645519(+) AGGTAA/GATCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HTR1E (87647024 - 87726401 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for HTR1E
         1 CNV: 99617

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    HTR1E for disorders           About GeneDecksing

    OMIM gene information: 182132    OMIM disorders: --

    9 diseases for HTR1E:    About MalaCards
    attention deficit hyperactivity disorder    autism spectrum disorder    chronic fatigue syndrome    skin papilloma
    adhd    papilloma    hermaphroditism    pharyngitis
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for HTR1E:
    Skin papilloma
    Genetic Association Database (GAD): HTR1E
    Human Genome Epidemiology (HuGE) Navigator: HTR1E (9 documents)

    Export disorders for HTR1E gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HTR1E gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with HTR1E)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. (PubMed id 1608964)1, 2, 3 McAllister G.... Whiting P. (1992)
    2. Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase. (PubMed id 1733778)1, 2, 9 Levy F.O.... Birnbaumer L. (1992)
    3. Human gene S31 encodes the pharmacologically defined serotonin 5- hydroxytryptamine1E receptor. (PubMed id 1513320)1, 2, 9 Zgombick J.M....Weinshank R.L. (1992)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers. (PubMed id 12627464)1, 4 Turecki G....Rouleau G.A. (2003)
    7. Characterization of single-nucleotide polymorphisms in coding regions of human genes. (PubMed id 10391209)1, 2 Cargill M....Lander E.S. (1999)
    8. Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15. (PubMed id 8001977)1, 9 Levy F.O....Gudermann T. (1994)
    9. 5-Hydroxytryptamine receptor subtype messenger RNAs in human dorsal root ganglia: a polymerase chain reaction study. (PubMed id 9316030)1, 9 Pierce P.A....Peroutka S.J. (1997)
    10. Association study of the serotoninergic system in mig raine in the Spanish population. (PubMed id 19455600)1 Corominas R....Cormand B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3354 HGNC: 5291 AceView: HTR1E Ensembl:ENSG00000168830 euGenes: HUgn3354
    ECgene: HTR1E Kegg: 3354 H-InvDB: HTR1E

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HTR1E Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HTR1E gene:
    Search GeneIP for patents involving HTR1E

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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