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Aliases for HTR1A Gene

Aliases for HTR1A Gene

  • 5-Hydroxytryptamine Receptor 1A 2 3 5
  • 5-Hydroxytryptamine (Serotonin) Receptor 1A, G Protein-Coupled 2 3
  • ADRB2RL1 3 4
  • ADRBRL1 3 4
  • 5-HT-1A 3 4
  • 5-HT1A 3 4
  • G-21 3 4
  • Guanine Nucleotide-Binding Regulatory Protein-Coupled Receptor 3
  • 5-Hydroxytryptamine (Serotonin) Receptor 1A 2
  • Serotonin Receptor 1A 4
  • 5-HT1a Receptor 3
  • 5HT1a 3
  • PFMCD 3

External Ids for HTR1A Gene

Previous HGNC Symbols for HTR1A Gene

  • ADRB2RL1
  • ADRBRL1

Previous GeneCards Identifiers for HTR1A Gene

  • GC05M063417
  • GC05M064794
  • GC05M063226
  • GC05M063272
  • GC05M063292
  • GC05M060210

Summaries for HTR1A Gene

Entrez Gene Summary for HTR1A Gene

  • This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]

GeneCards Summary for HTR1A Gene

HTR1A (5-Hydroxytryptamine Receptor 1A) is a Protein Coding gene. Diseases associated with HTR1A include Periodic Fever, Menstrual Cycle Dependent and Generalized Anxiety Disorder. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and G-protein coupled serotonin receptor activity. An important paralog of this gene is HTR1B.

UniProtKB/Swiss-Prot for HTR1A Gene

  • G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Tocris Summary for HTR1A Gene

  • The serotonin 5-HT1A receptor was the first 5-HT receptor to be fully sequenced. 5-HT1A receptor binding sites are located primarily in limbic brain areas, notably the hypothalamus and cortical areas. The human gene encoding this receptor has been localized to chromosome 5.

Gene Wiki entry for HTR1A Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HTR1A Gene

Genomics for HTR1A Gene

Regulatory Elements for HTR1A Gene

Enhancers for HTR1A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F063959 0.8 Ensembl ENCODE 0.8 +2.8 2835 1.3 CTCF SMARCA4 POLR2A TEAD4 RAD21 EZH2 RNF180 HTR1A LOC105378999
GH05F063958 0.4 ENCODE 0.8 +3.7 3679 0.2 TEAD4 HTR1A LOC105378999
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HTR1A on UCSC Golden Path with GeneCards custom track

Genomic Location for HTR1A Gene

Chromosome:
5
Start:
63,960,048 bp from pter
End:
63,962,507 bp from pter
Size:
2,460 bases
Orientation:
Minus strand

Genomic View for HTR1A Gene

Genes around HTR1A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HTR1A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HTR1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HTR1A Gene

Proteins for HTR1A Gene

  • Protein details for HTR1A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P08908-5HT1A_HUMAN
    Recommended name:
    5-hydroxytryptamine receptor 1A
    Protein Accession:
    P08908
    Secondary Accessions:
    • Q6LAE7

    Protein attributes for HTR1A Gene

    Size:
    422 amino acids
    Molecular mass:
    46107 Da
    Quaternary structure:
    • Heterodimer; heterodimerizes with GPER1.

neXtProt entry for HTR1A Gene

Post-translational modifications for HTR1A Gene

  • Ubiquitination at Lys 334
  • Glycosylation at Asn 10, Asn 11, and Asn 24
  • Modification sites at PhosphoSitePlus

Other Protein References for HTR1A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HTR1A Gene

Domains & Families for HTR1A Gene

Suggested Antigen Peptide Sequences for HTR1A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P08908

UniProtKB/Swiss-Prot:

5HT1A_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Family:
  • Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
genes like me logo Genes that share domains with HTR1A: view

Function for HTR1A Gene

Molecular function for HTR1A Gene

GENATLAS Biochemistry:
5-hydroxytryptamine (serotonin) receptor,subtype IA,G protein coupled receptor superfamily,inhibiting adenylate cyclase
UniProtKB/Swiss-Prot Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Gene Ontology (GO) - Molecular Function for HTR1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004993 G-protein coupled serotonin receptor activity IEA,IMP 22957663
GO:0005515 protein binding IPI 22035699
GO:0030594 neurotransmitter receptor activity IBA --
genes like me logo Genes that share ontologies with HTR1A: view
genes like me logo Genes that share phenotypes with HTR1A: view

Human Phenotype Ontology for HTR1A Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for HTR1A Gene

MGI Knock Outs for HTR1A:

Animal Model Products

miRNA for HTR1A Gene

miRTarBase miRNAs that target HTR1A

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR1A

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for HTR1A Gene

Localization for HTR1A Gene

Subcellular locations from UniProtKB/Swiss-Prot for HTR1A Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HTR1A gene
Compartment Confidence
plasma membrane 5
extracellular 2
nucleus 2
cytoskeleton 1
mitochondrion 1
cytosol 1

Gene Ontology (GO) - Cellular Components for HTR1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA,TAS --
GO:0005887 integral component of plasma membrane IEA,IDA 22957663
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030425 dendrite IBA --
genes like me logo Genes that share ontologies with HTR1A: view

Pathways & Interactions for HTR1A Gene

genes like me logo Genes that share pathways with HTR1A: view

Gene Ontology (GO) - Biological Process for HTR1A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001662 behavioral fear response ISS --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA,IMP 22957663
GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway IDA 8393041
GO:0007210 serotonin receptor signaling pathway IEA,ISS --
genes like me logo Genes that share ontologies with HTR1A: view

No data available for SIGNOR curated interactions for HTR1A Gene

Drugs & Compounds for HTR1A Gene

(248) Drugs for HTR1A Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Aripiprazole Approved, Investigational Pharma Antagonist, agonist, Target, antagonist, partial agonist Antipsychotic, High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist 353
Quetiapine Approved Pharma Antagonist, agonist, Target, antagonist 0
Ziprasidone Approved Pharma Antagonist, agonist, Target 5-HT (serotonin)/dopamine receptor antagonist 145
Risperidone Approved, Investigational Pharma Antagonist, antagonist, Target SR-2A inhibitor 487
Lisuride Approved Pharma Antagonist, agonist, Target 5

(48) Additional Compounds for HTR1A Gene - From: IUPHAR, Novoseek, Tocris, and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(-)-quinpirole
Full agonist, Agonist
(+)-flesinoxan
Full agonist, Agonist
(R)-flurocarazolol
Antagonist
(S)-flurocarazolol
Antagonist
[<sup>3</sup>H]NAD 299
Antagonist

(5) Tocris Compounds for HTR1A Gene

Compound Action Cas Number
(R)-(+)-8-Hydroxy-DPAT hydrobromide Selective 5-HT1A agonist. Enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529) 78095-19-9
(S)-WAY 100135 dihydrochloride Potent, selective 5-HT1A antagonist 149007-54-5
Cyanopindolol hemifumarate 5-HT1A/1B antagonist. Also beta-adrenergic antagonist 69906-86-1
RU 24969 hemisuccinate 5-HT1B/1A agonist 66611-27-6
WAY 100635 maleate Potent, 5-HT1A silent antagonist. Also D4 agonist 634908-75-1

(40) ApexBio Compounds for HTR1A Gene

Compound Action Cas Number
(R)-(+)-8-Hydroxy-DPAT hydrobromide 78095-19-9
(S)-WAY 100135 dihydrochloride 5-HT1A receptor antagonist,potent and selective 149007-54-5
5-Carboxamidotryptamine maleate 74885-72-6
8-Hydroxy-DPAT hydrobromide 76135-31-4
8-Hydroxy-PIPAT oxalate 1451210-48-2
Adoprazine 5-HT1A receptor agonist and full D2/3 receptor antagonist 222551-17-9
Asenapine hydrochloride Atypical antipsychotic 1412458-61-7
BMY 14802 hydrochloride Sigma receptor antagonist 105565-55-7
BMY 7378 5-HT1A partial agonist and α1D adrenoceptor antagonist 21102-95-4
BP 554 maleate Selective 5-HT1A agonist 1221401-95-1
Buspirone HCl 33386-08-2
Citalopram hydrobromide 59729-32-7
Cyanopindolol hemifumarate 69906-86-1
Eltoprazine 98224-03-4
Flopropione 2295-58-1
Fluvoxamine 54739-18-3
Iloperidone hydrochloride 1299470-39-5
Ipsapirone 95847-70-4
L-703,664 succinate 144776-01-2
Lamotrigine 5-HT inhibitor 84057-84-1
Lofepramine 23047-25-8
LP 20 hydrochloride 1386928-34-2
Lurasidone HCl Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor 367514-88-3
MDL 72832 hydrochloride 113777-40-5
MDL 73005EF hydrochloride 102908-60-1
Methiothepin maleate 19728-88-2
Methylergometrine maleate 57432-61-8
Mianserin HCl 5-HT2 receptor antagonist 21535-47-7
MM 77 dihydrochloride 159187-70-9
NAN-190 hydrobromide 115338-32-4
Paroxetine maleate 64006-44-6
S 14506 hydrochloride 286369-38-8
Sumatriptan Succinate 5-HT1 receptor agonist 103628-48-4
Tropisetron Hydrochloride 105826-92-4
Vilazodone Combined SSRI and 5-HT1A receptor partial agonist 163521-12-8
Vilazodone Hydrochloride Combined SSRI and 5-HT1A receptor partial agonist 163521-08-2
WAY-100635 5-HT1A receptor antagonist,potent and selective 162760-96-5
WAY-100635 Maleate 5-HT1A receptor agonist 1092679-51-0
WAY-100635 maleate salt 5-hydroxytryptamine 1A antagonist 634908-75-1
Ziprasidone 5-HT (serotonin)/dopamine receptor antagonist 146939-27-7
genes like me logo Genes that share compounds with HTR1A: view

Drug Products

Transcripts for HTR1A Gene

mRNA/cDNA for HTR1A Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HTR1A Gene

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for HTR1A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for HTR1A Gene

No ASD Table

Relevant External Links for HTR1A Gene

GeneLoc Exon Structure for
HTR1A
ECgene alternative splicing isoforms for
HTR1A

Expression for HTR1A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HTR1A Gene

mRNA differential expression in normal tissues according to GTEx for HTR1A Gene

This gene is overexpressed in Brain - Hippocampus (x13.8), Brain - Frontal Cortex (BA9) (x9.7), Brain - Cortex (x8.9), Brain - Anterior cingulate cortex (BA24) (x7.2), and Brain - Amygdala (x4.4).

Protein differential expression in normal tissues from HIPED for HTR1A Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for HTR1A Gene



Protein tissue co-expression partners for HTR1A Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of HTR1A Gene:

HTR1A

SOURCE GeneReport for Unigene cluster for HTR1A Gene:

Hs.247940

mRNA Expression by UniProt/SwissProt for HTR1A Gene:

P08908-5HT1A_HUMAN
Tissue specificity: Detected in lymph nodes, thymus and spleen. Detected in activated T-cells, but not in resting T-cells.
genes like me logo Genes that share expression patterns with HTR1A: view

Primer Products

Orthologs for HTR1A Gene

This gene was present in the common ancestor of animals.

Orthologs for HTR1A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HTR1A 34 35
  • 99.68 (n)
cow
(Bos Taurus)
Mammalia 5HTR1A 35
  • 92 (a)
OneToOne
HTR1A 34
  • 88.31 (n)
dog
(Canis familiaris)
Mammalia HTR1A 34 35
  • 89.1 (n)
mouse
(Mus musculus)
Mammalia Htr1a 34 16 35
  • 85.59 (n)
rat
(Rattus norvegicus)
Mammalia Htr1a 34
  • 85.47 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia HTR1A 35
  • 65 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 33 (a)
ManyToMany
chicken
(Gallus gallus)
Aves HTR1A 34 35
  • 77.64 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia htr1a 34
  • 70.29 (n)
African clawed frog
(Xenopus laevis)
Amphibia htr1a-A 34
zebrafish
(Danio rerio)
Actinopterygii htr1aa 34
  • 71.33 (n)
htr1ab 35
  • 69 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta 5-HT1A 36 34
  • 58.61 (n)
5-HT1B 36
  • 49 (a)
DopR2 36
  • 45 (a)
CG7431 36
  • 42 (a)
5-HT7 36
  • 39 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta GPR5HT1A 34
  • 56.36 (n)
worm
(Caenorhabditis elegans)
Secernentea ser-4 34
  • 47.53 (n)
F14D12.6 36
  • 30 (a)
Species where no ortholog for HTR1A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HTR1A Gene

ENSEMBL:
Gene Tree for HTR1A (if available)
TreeFam:
Gene Tree for HTR1A (if available)

Paralogs for HTR1A Gene

(19) SIMAP similar genes for HTR1A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HTR1A: view

Variants for HTR1A Gene

Sequence variations from dbSNP and Humsavar for HTR1A Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs6295 drug-response 63,962,738(-) AAAAA(C/G)GAAGA upstream-variant-2KB
rs367956927 Pathogenic 63,962,199(+) CTCTC(-/T)TCTCT utr-variant-5-prime
rs112021589 -- 63,962,988(+) AACTG(C/T)ATCTC upstream-variant-2KB
rs112448748 -- 63,963,982(+) GTTCA(A/C)ATCTG upstream-variant-2KB
rs112542715 -- 63,963,528(+) TTAGC(C/T)TCCTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for HTR1A Gene

Variant ID Type Subtype PubMed ID
nsv4860 CNV insertion 18451855
nsv598351 CNV gain 21841781

Variation tolerance for HTR1A Gene

Residual Variation Intolerance Score: 50.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.89; 35.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HTR1A Gene

Human Gene Mutation Database (HGMD)
HTR1A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HTR1A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HTR1A Gene

Disorders for HTR1A Gene

MalaCards: The human disease database

(47) MalaCards diseases for HTR1A Gene - From: OMIM, ClinVar, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
periodic fever, menstrual cycle dependent
  • periodic fever, menstrual cycle-dependent
generalized anxiety disorder
  • anxiety generalized
agoraphobia
  • fear of open spaces
anxiety disorder
  • anxiety
mood disorder
  • episodic mood disorder
- elite association - COSMIC cancer census association via MalaCards
Search HTR1A in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

5HT1A_HUMAN
  • Periodic fever, menstrual cycle-dependent (PFMC) [MIM:614674]: A condition characterized by recurrent fevers up to 40 degrees Celsius associated with the luteal phase of the menstrual cycle. Women show menstrual cycle-dependent physiologic changes in relation to sex hormone levels. Because ovulation triggers a significant change in the hormonal milieu that is similar to local inflammation, a 0.5 to 1.0 degree Celsius increase in basal body temperature after ovulation is commonly associated with progesterone secretion and is believed to be triggered by the induction of several inflammatory cytokines. {ECO:0000269 PubMed:21990073}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for HTR1A

Genetic Association Database (GAD)
HTR1A
Human Genome Epidemiology (HuGE) Navigator
HTR1A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HTR1A
genes like me logo Genes that share disorders with HTR1A: view

No data available for Genatlas for HTR1A Gene

Publications for HTR1A Gene

  1. A genetic variant of HTR2C may play a role in the manifestation of Tourette syndrome. (PMID: 20010450) Dehning S. … Zill P. (Psychiatr. Genet. 2010) 3 22 46 64
  2. Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response. (PMID: 19077664) Peters E.J. … Hamilton S.P. (Pharmacogenet. Genomics 2009) 3 22 46 64
  3. Association of major depression with rare functional variants in norepinephrine transporter and serotonin1A receptor genes. (PMID: 19105200) Haenisch B. … BAPnisch H. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009) 3 22 46 64
  4. Positron emission tomography quantification of serotonin-1A receptor binding in medication-free bipolar depression. (PMID: 19278673) Sullivan G.M. … Parsey R.V. (Biol. Psychiatry 2009) 3 22 46 64
  5. Interaction between genetic polymorphisms and stressful life events in first episode depression. (PMID: 19339052) Bukh J.D. … Vedel Kessing L. (J Affect Disord 2009) 3 22 46 64

Products for HTR1A Gene

Sources for HTR1A Gene

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