HTLVR Gene
protein-coding GIFtS: 14
GCID: GC17U990041
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human T-cell leukemia virus (I and II) receptor
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Aliases
for HTLVR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
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| Human T-Cell Leukemia Virus (I And II) Receptor1 2 | | Receptor For HTLV-1 And HTLV-22 |
Export aliases for HTLVR gene to outside databases |
Summaries
for HTLVR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
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Genomic Views
for HTLVR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for HTLVR
Other transcription factors
Search SABiosciences Chromatin IP Primers for HTLVR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HTLVR |
Genomic Location:
Chromosome:17
Entrez Gene cytogenetic band: 17q HGNC cytogenetic band: 17qGeneLoc information about chromosome 17 |
Proteins
for HTLVR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for HTLVR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for HTLVR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Molecular Function:
Genatlas biochemistry entry for HTLVR:human T cell leukemia virus (I and II) receptor
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for HTLVR | |  | Search LifeMap BioReagents cell lines for HTLVR |
Pathways & Interactions
for HTLVR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HTLVR
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Drugs & Compounds
for HTLVR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HTLVR for compounds About GeneDecksing
 Browse Tocris compounds for HTLVR
2 Novoseek chemical compound relationships for HTLVR gene About this table
Search CenterWatch for drugs/clinical trials and news about HTLVR 
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Transcripts
for HTLVR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Expression
for HTLVR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
SABiosciences Custom PCR Arrays for HTLVR
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat HTLVR | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HTLVR | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HTLVR |
Orthologs
for HTLVR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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Paralogs
for HTLVR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HTLVR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for HTLVR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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HTLVR for disorders About GeneDecksing
OMIM gene information: 143090
OMIM disorders: --
20/22  diseases for HTLVR (see all 22): About MalaCardst-cell leukemia human t-cell leukemia virus type 1 sclerosing cholangitis leukemia
primary sclerosing cholangitis mycosis fungoides toxic shock syndrome cholangitis
diabetes mellitus graves' disease adult t-cell leukemia rheumatoid arthritis
acute lymphocytic leukemia tetanus multiple sclerosis lymphocytic leukemia
cutaneous t cell lymphoma autoimmune thyroiditis arthritis thyroiditis
10/11 Novoseek disease relationships for HTLVR gene (see all 11) About this table
Export disorders for HTLVR gene to outside databases
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Publications
for HTLVR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HTLVR gene, integrated from 9 sources (see all 112):
(articles sorted by number of sources associating them with HTLVR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human T-cell leukemia virus type 1 receptor expression among syncytium-resistant cell lines revealed by a novel surface glycoprotein-immunoadhesin. (PubMed id 11483777)1, 3 Jassal S.R....Brighty D.W. (2001)
- Assignment of the possible HTLV receptor gene to chromosome 17q21-q23. (PubMed id 9330634)1, 3 Tajima Y....Camerini D. (1997)
- Human T cell leukemia viruses use a receptor determin ed by human chromosome 17. (PubMed id 3201246)1, 3 Sommerfelt M.A....Weiss R.A. (1988)
- The HTLV receptor is an early T-cell activation marker whose expression requires de novo protein synthesis. (PubMed id 12393496)1 Manel N....Sitbon M. (2003)
- Use of a murine T-cell hybridoma expressing human T-c ell receptor alpha- and beta-gene products as a tool for the production of huma n T-cell receptor-specific monoclonal antibodies. (PubMed id 1293080)9 Zumla A....Lechler R. (1992)
- [Development of a high-efficient assay for amplifying Vbeta-encoding genes of human T-cell receptor.] (PubMed id 19737485)9 Ye H.Y....Xu D.P. (2009)
- Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice. (PubMed id 17949947)9 Gebe J.A....Nepom G.T. (2008)
- Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice. (PubMed id 15311276)9 Quaratino S....Maiuri L. (2004)
- Nomenclature of the human T cell receptor genes. (PubMed id 18432649)9 Lefranc M.P. (2001)
- A conserved sequence block in the murine and human T cell receptor Jalpha loci interacts with developmentally regulated nucleoprotein complexes in vitro and associates with GATA-3 and octamer-binding factors in vivo. (PubMed id 11385613)9 Chen M.L. and Kuo C.L. (2001)
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External Searches for HTLVR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing HTLVR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing HTLVR gene
(According to HUGE)
About This Section
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Specialized Databases showing HTLVR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for HTLVR gene:
Search GeneIP for patents involving HTLVR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HTLVR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HTLVR | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HTLVR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HTLVR | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HTLVR | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HTLVR | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HTLVR |
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| | | | Search Tocris compounds for HTLVR |
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 | | | | |  |  |  |  | | | | Search ThermoFisher Antibodies for HTLVR |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HTLVR |
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Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013
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