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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HTATSF1 Gene

protein-coding   GIFtS: 58
GCID: GC0XP135579

HIV-1 Tat Specific Factor 1

(Previous name: HIV TAT specific factor 1)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
HIV-1 Tat Specific Factor 11 2     Cofactor Required For Tat Activation Of HIV-1 Transcription2
HIV TAT Specific Factor 11 2     dJ196E23.22
TAT-SF12     HIV Tat-Specific Factor 12
TATSF12     Tat-SF13

External Ids:    HGNC: 52761   Entrez Gene: 273362   Ensembl: ENSG000001022417   OMIM: 3003465   UniProtKB: O437193   

Export aliases for HTATSF1 gene to outside databases

Previous GC identifers: GC0XP130151 GC0XP132425 GC0XP133524 GC0XP134285 GC0XP135305 GC0XP135406 GC0XP124849


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HTATSF1 Gene:
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by
HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a
dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation.
Alternatively spliced transcript variants have been found for this gene.(provided by RefSeq, Sep 2009)

GeneCards Summary for HTATSF1 Gene: 
HTATSF1 (HIV-1 Tat specific factor 1) is a protein-coding gene. Diseases associated with HTATSF1 include anemia, and neuronitis. GO annotations related to this gene include RNA binding and nucleotide binding.

UniProtKB/Swiss-Prot: HTSF1_HUMAN, O43719
Function: Functions as a general transcription factor playing a role in the process of transcriptional elongation.
May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by
HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced
transcription of the virus

Gene Wiki entry for HTATSF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_011786.16  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HTATSF1 gene promoter:
         Pbx1a   STAT5A   Evi-1   Gfi-1   c-Rel   PPAR-gamma1   FOXC1   FOXO1a   PPAR-gamma2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHTATSF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for HTATSF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HTATSF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq26.3   Ensembl cytogenetic band:  Xq26.3   HGNC cytogenetic band: Xq26.3

HTATSF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HTATSF1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP135579:  view genomic region     (about GC identifiers)

Start:
135,579,238 bp from pter      End:
135,594,505 bp from pter
Size:
15,268 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HTSF1_HUMAN, O43719 (See protein sequence)
Recommended Name: HIV Tat-specific factor 1  
Size: 755 amino acids; 85853 Da
Subunit: Component of a complex which is at least composed of HTATSF1/Tat-SF1, the P-TEFb complex components CDK9
and CCNT1, RNA polymerase II, SUPT5H, and NCL/nucleolin. Interacts with GTF2F2/RAP30 and POLR2A. Interacts with
TCERG1/CA150. Interacts with SF3A2/SAP62 and the spliceosomal U small nuclear ribonucleoproteins (snRNPs)
Subcellular location: Nucleus
Sequence caution: Sequence=AAB18823.1; Type=Frameshift; Positions=383, 391, 393; Sequence=BAD92540.1;
Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for HTATSF1:
2DIT (3D)    
Secondary accessions: D3DWG9 Q59G06 Q99730

Explore the universe of human proteins at neXtProt for HTATSF1: NX_O43719

Explore proteomics data for HTATSF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43719

  • HTATSF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HTATSF1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001156752.1  NP_055315.2  

    ENSEMBL proteins: 
     ENSP00000411381   ENSP00000412420   ENSP00000218364   ENSP00000442699  

    Human Recombinant Protein Products for HTATSF1: 
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    HTATSF1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry O43719

    ProtoNet protein and cluster: O43719

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: HTSF1_HUMAN, O43719
    Domain: The RRM domains mediate interaction with U snRNPs
    Similarity: Belongs to the HTATSF1 family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    HTATSF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HTSF1_HUMAN, O43719
    Function: Functions as a general transcription factor playing a role in the process of transcriptional elongation.
    May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by
    HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced
    transcription of the virus

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
         
    HTATSF1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HTATSF1:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HTATSF1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HTATSF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/604 Interacting proteins for HTATSF1 (O437192, 3 ENSP000002183644) via UniProtKB, MINT, STRING, and/or I2D (see all 604)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SF3A2Q154282, 3, ENSP000002214944MINT-5206124 I2D: score=4 STRING: ENSP00000221494
    SNRNP70P086212, 3, ENSP000002214484MINT-7945693 I2D: score=2 STRING: ENSP00000221448
    SNRPB2P085792, 3, ENSP000002460714MINT-7945693 I2D: score=2 STRING: ENSP00000246071
    CCNT1O605632, 3, ENSP000002619004MINT-7945693 I2D: score=1 STRING: ENSP00000261900
    ZNF512BQ96KM62, 3MINT-60795 I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS10454543
    GO:0019079viral genome replication TAS10454543
    GO:0032784regulation of DNA-dependent transcription, elongation TAS10454543

    HTATSF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HTATSF1 (HTSF1)

    Search CenterWatch for drugs/clinical trials and news about HTATSF1 / HTSF1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for HTATSF1 gene (2 alternative transcripts): 
    NM_001163280.1  NM_014500.4  

    Unigene Cluster for HTATSF1:

    HIV-1 Tat specific factor 1
    Hs.204475  [show with all ESTs]
    Unigene Representative Sequence: NM_001163280
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000448450 ENST00000425695 ENST00000218364(uc004ezx.3) ENST00000535601(uc004ezw.3)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate HTATSF1:
    hsa-miR-7-1* hsa-miR-7-2*
    SwitchGear 3'UTR luciferase reporter plasmidHTATSF1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HTATSF1
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    Additional mRNA sequence: 

    AB209303.1 AK225870.1 AK299403.1 BC009896.2 BT006886.1 U76992.1 

    11 DOTS entries:

    DT.215426  DT.92443441  DT.92443426  DT.95173876  DT.100816512  DT.75192416  DT.102831969  DT.102831971 
    DT.86855551  DT.95173873  DT.100816516 

    24/193 AceView cDNA sequences (see all 193):

    AA629738 BQ719792 NM_014500 AU142741 BU186796 AI434543 BE464008 BC009896 
    AI433897 BU633070 BE463411 AA306171 BT006886 AA120916 AW135174 BG256911 
    CB139562 AI670885 BM784531 CN480273 BF223418 AI566083 BU608260 AI027753 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HTATSF1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b
    SP1:              -                             -                                                                     
    SP2:                                            -                                                                     
    SP3:              -     -                       -                                                                     
    SP4:              -     -     -                 -                                                                     
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for HTATSF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HTATSF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAATAATA
    HTATSF1 Expression
    About this image


    See HTATSF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HTATSF1

    SOURCE GeneReport for Unigene cluster: Hs.204475

    UniProtKB/Swiss-Prot: HTSF1_HUMAN, O43719
    Tissue specificity: Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Array including HTATSF1: 
              HIV Host Response in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HTATSF1 gene from 10/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Htatsf11 , 5 HIV TAT specific factor 11, 5 82.55(n)1
    78.54(a)1
      X (30.81 cM)5
    724591  NM_028242.21  NP_082518.11 
     570535835 
    chicken
    (Gallus gallus)
    Aves HTATSF11 HIV-1 Tat specific factor 1 68.65(n)
    65.37(a)
      422245  XM_001233031.2  XP_001233032.1 
    lizard
    (Anolis carolinensis)
    Reptilia HTATSF16
    Uncharacterized protein
    60(a)
    1 ↔ 1
    GL343562.1(152393-162377)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3987362 hypothetical protein LOC398736 76.85(n)    BC059346.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc662522 similar to HIV TAT specific factor 1 75.31(n)   394178  BC055565.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG60493 RNA binding 44(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea Y65B4A.13   -- 38(a)   I(654131-658647)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CUS2(YNL286W)4
    CUS21
    Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs) less4
    Cus2p1
    46.41(n)1
    33.82(a)1
      14(95223-96080)4
    8554301, 4  NP_014113.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ELF91 HIV Tat-specific factor 1 46.55(n)
    34.28(a)
      831486  NM_121631.2  NP_197130.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g04964001 hypothetical protein 49.6(n)
    37.2(a)
      4336279  NM_001059735.1  NP_001053200.1 


    ENSEMBL Gene Tree for HTATSF1 (if available)
    TreeFam Gene Tree for HTATSF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HTATSF1 gene

    HTATSF1 for paralogs           About GeneDecksing


    5/8 Pseudogenes.org Pseudogenes for HTATSF1 (see all 8)
    PGOHUM00000243042 PGOHUM00000243593 PGOHUM00000245415 PGOHUM00000236896 PGOHUM00000243031


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/231 SNPs in HTATSF1 are shown (see all 231)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1928249381,2
    --135535691(+) GAGTTA/GTTCTA 1 -- us2k10--------
    rs1857044501,2
    --135535867(+) CTTCTC/TCGCTG 1 -- us2k10--------
    rs1893133221,2
    --135535916(+) AGCAGG/TCCTCT 1 -- us2k10--------
    rs1810025761,2
    --135536167(+) CGGTTA/GTGGTA 2 -- us2k10--------
    rs30278361,2
    C,H--135536173(+) TGGTAG/AAGCCG 2 -- us2k14Minor allele frequency- A:0.00NS EA 418
    rs2021660371,2
    C--135536428(+) AATTT-/AAAAAA 2 -- us2k10--------
    rs1835499181,2
    --135536429(+) AATTTA/TAAAAA 2 -- us2k10--------
    rs1880405461,2
    --135536670(+) GTATTG/TTTTAA 2 -- us2k10--------
    rs1814451791,2
    C--135536736(+) TTTTTG/TGGGGT 2 -- us2k10--------
    rs1861880011,2
    --135536769(+) GGACCG/TGGAAC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for HTATSF1 (135579238 - 135594505 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HTATSF1: --

    Locus Specific Mutation Databases (LSDB): HTATSF1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing HTATSF1
    DNA2.0 Custom Variant and Variant Library Synthesis for HTATSF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300346    OMIM disorders: --

    2 diseases for HTATSF1:    About MalaCards
    anemia    neuronitis


    HTATSF1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Genetic Association Database (GAD): HTATSF1
    Human Genome Epidemiology (HuGE) Navigator: HTATSF1 (1 document)

    Export disorders for HTATSF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HTATSF1 gene, integrated from 9 sources (see all 59):
    (articles sorted by number of sources associating them with HTATSF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. (PubMed id 8849451)1, 2, 3 Zhou Q. and Sharp P.A. (1996)
    2. Stimulatory effect of splicing factors on transcriptional elongation. (PubMed id 11780068)1, 2, 9 Fong Y.W. and Zhou Q. (2001)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    5. Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression. (PubMed id 15905670)1, 2 Misse D.... Veas F. (2005)
    6. FF domains of CA150 bind transcription and splicing factors through multiple weak interactions. (PubMed id 15485897)1, 2 Smith M.J.... Pawson T. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Nef triggers a transcriptional program in T cells imitating single- signal T cell activation and inducing HIV virulence mediators. (PubMed id 11420046)1, 2 Simmons A.... McMichael A. (2001)
    9. Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter. (PubMed id 10913173)1, 2 Fong Y.W. and Zhou Q. (2000)
    10. Tat-SF1 protein associates with RAP30 and human SPT5 proteins. (PubMed id 10454543)1, 2 Kim J.B.... Sharp P.A. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27336 HGNC: 5276 AceView: HTATSF1 Ensembl:ENSG00000102241 euGenes: HUgn27336
    ECgene: HTATSF1 H-InvDB: HTATSF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HTATSF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HTATSF1 gene:
    Search GeneIP for patents involving HTATSF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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