HSPH1 Gene

Aliases
for HSPH1 gene

Previous GC identifers: GC13M025697 GC13M030645 GC13M029508 GC13M030608 GC13M012522

Summaries
for HSPH1 gene

Genomic Views
for HSPH1 gene

RefSeq DNA sequence:

NC_000013.10  NC_018924.1  NT_024524.14  

SwitchGear Promoter luciferase reporter plasmid: HSPH1 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPH1

HSPH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M031710:  view genomic region     (about GC identifiers)

Proteins
for HSPH1 gene

Explore the universe of human proteins at neXtProt for HSPH1: NX_Q92598

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: HSPH1 OriGene Protein Over-expression Lysate: HSPH1 OriGene Custom Protein Services for HSPH1
	GenScript Custom Purified and Recombinant Proteins Services for HSPH1
	Novus Biologicals HSPH1 Proteins Novus Biologicals HSPH1 Lysates
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for HSPH1
	Uscn Proteins for HSPH1

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of HSPH1
	R&D Systems Antibodies for HSPH1
	OriGene Antibodies (see all 3): HSPH1 OriGene Custom Antibody Services for HSPH1
	GenScript Custom Superior Antibodies Services for HSPH1
	Novus Biologicals HSPH1 Antibodies
	Abcam antibodies for HSPH1
	Uscn Antibodies for HSPH1
	ThermoFisher Antibody for HSPH1

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for HSPH1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for HSPH1

Protein Domains /
Families
for HSPH1 gene

ProtoNet protein and cluster: Q92598

Function
for HSPH1 gene

miRNA Products:		OriGene 3'-UTR Clone: HSPH1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPH1
		8 QIAGEN miScript miRNA Assays for microRNAs that regulate HSPH1:
		hsa-miR-587 hsa-miR-513b hsa-miR-204 hsa-miR-369-3p hsa-miR-9* hsa-miR-651 hsa-miR-3692 hsa-miR-211
		SwitchGear 3'UTR luciferase reporter plasmid: HSPH1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPH1 (see all 4) OriGene shRNA RFP: HSPH1 OriGene siRNA: HSPH1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPH1

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for HSPH1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPH1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPH1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HSPH1 (NM_006644)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPH1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPH1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HSPH1
		Search LifeMap BioReagents cell lines for HSPH1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPH1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

Pathways & Interactions
for HSPH1 gene

	Super-pathway	contained gene-specific pathways
1	Protein processing in endoplasmic reticulum	Protein processing in endoplasmic reticulum 1.00

1         Kegg Pathway  (Kegg details for HSPH1)

Protein processing in endoplasmic reticulum

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for HSPH1 gene

Transcripts
for HSPH1 gene

Expression
for HSPH1 gene

HSPH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAAAGTGTG

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	OvaryPrimary FolliclePrimary Oocyte			Female Gametocytes, Germ Cells
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Secondary follicles (Primary Cell)			Ovary, Reproductive System

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPH1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HSPH1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPH1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPH1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPH1

Orthologs
for HSPH1 gene

Paralogs
for HSPH1 gene

Paralogs for HSPH1 gene

HYOU1²  HSPA4L²  HSPA4²  

14 SIMAP similar genes for HSPH1 using alignment to 4 protein entries:     HS105_HUMAN (see all proteins):

HSPA4    HS24/p52    HS24/P52    HSPA4L    HSP70-1    LOC401308

HSPA7    HSPA1L    HSPA14    HSPA5    HSPA6    HSPA8

HSPA1A    HSPA1B

HSPH1 for paralogs           About GeneDecksing

Genomic Variants
for HSPH1 gene

10/578 NCBI SNPs in HSPH1 are shown (see all 578)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1924962951,2		--	31710323(+)	CTAAAC/TCTACC	1	--	int1		0	--	--	--	--
rs79821411,2	C,F,H,	--	31710355(+)	AAGTAT/CGTCTT	1	--	int1		34		NS EA NA WA CSA	3177
rs1826530101,2		--	31710383(+)	ATTTAC/TGCAGT	1	--	int1		0	--	--	--	--
rs1147034101,2	C,	--	31710460(+)	TAACAC/TAGACA	1	--	int1		0	--	--	--	--
rs1928628001,2		--	31710480(+)	ATATAC/GCCCCA	1	--	int1		0	--	--	--	--
rs1443133571,2		--	31710534(+)	ACAATA/GTTTTC	1	--	int1		0	--	--	--	--
rs2016657911,2		--	31710776(+)	GACAC-/CATAAGAT	1	--	ut31		0	--	--	--	--
rs38032831,2	C,H	--	31710884(-)	CTCTCT/CCACTA	1	--	ut31 ese3 trp3		4		NS EA	416
rs1146109691,2	F,	--	31710970(+)	TCAAAG/ACAAAA	1	--	ut31		1		WA	118
rs1843818411,2		--	31710992(+)	CTTGGA/CCAGAA	1	--	ut31		0	--	--	--	--

HapMap Linkage Disequilibrium report for HSPH1 (31710762 - 31736525 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for HSPH1
     1 CNV: 8752

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPH1

DNA2.0 Custom Variant and Variant Library Synthesis for HSPH1

Disorders / Diseases
for HSPH1 gene

19 diseases for HSPH1

4 Novoseek disease relationships for HSPH1 gene    About this table

Publications
for HSPH1 gene

PubMed articles for HSPH1 gene, integrated from 9 sources (see all 88): (articles sorted by number of sources associating them with HSPH1)

Utopia: connect your pdf to the dynamic world of online information

1. Molecular cloning, expression and localization of human 105 kDa heat shock protein, hsp105. (PubMed id 9931472)^{1, 2, 3, 9} Ishihara K.... Hatayama T. (1999)
2. Characterization of human colon cancer antigens recognized by autologous antibodies. (PubMed id 9610721)^{1, 2, 3} Scanlan M.J....Old L.J. (1998)
3. DNA vaccination of HSP105 leads to tumor rejection of colorectal cancer and melanoma in mice through activation of both CD4 T cells and CD8 T cells. (PubMed id 16232202)^{1, 2, 9} Miyazaki M.... Nishimura Y. (2005)
4. The distribution and localization of hsp110 in brain. (PubMed id 10865058)^{1, 2, 9} Hylander B.L.... Subjeck J.R. (2000)
5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
6. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)^{1, 2} Dunham A.... Ross M.T. (2004)
7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
8. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
9. Differential expression of heat shock protein 105 in melanoma and melanocytic naevi. (PubMed id 18477890)^{1, 9} Muchemwa F.C....Ihn H. (2008)
10. Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. (PubMed id 12952910)^{1, 9} Nicchitta C.V. (2003)

External Searches for HSPH1 gene

Genome Databases showing HSPH1 gene

Other Databases showing HSPH1 gene

Specialized Databases showing HSPH1 gene

Products
for HSPH1 gene