Aliases for HSPE1 Gene
External Ids for HSPE1 Gene
Previous GeneCards Identifiers for HSPE1 Gene
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
GeneCards Summary for HSPE1 Gene
HSPE1 (Heat Shock Protein Family E (Hsp10) Member 1) is a Protein Coding gene. Diseases associated with HSPE1 include exocervical carcinoma and sennetsu fever. GO annotations related to this gene include poly(A) RNA binding and chaperone binding.
UniProtKB/Swiss-Prot for HSPE1 Gene
Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.