Aliases for HSPBP1 Gene
External Ids for HSPBP1 Gene
Previous GeneCards Identifiers for HSPBP1 Gene
GeneCards Summary for HSPBP1 Gene
HSPBP1 (HSPA (Heat Shock 70kDa) Binding Protein, Cytoplasmic Cochaperone 1) is a Protein Coding gene. Among its related pathways are Regulation of degradation of deltaF508 CFTR in CF and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF). GO annotations related to this gene include binding and enzyme inhibitor activity.
UniProtKB/Swiss-Prot for HSPBP1 Gene
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.