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HSPBAP1 Gene

protein-coding   GIFtS: 52
GCID: GC03M122407

HSPB (Heat Shock 27kDa) Associated Protein 1

(Previous name: HSPB (heat shock 27kD) associated protein 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
HSPB (Heat Shock 27kDa) Associated Protein 11 2     HSPB1-Associated Protein 12
27 KDa Heat Shock Protein-Associated Protein 12 3     Protein Associating With Small Stress Protein PASS12
PASS12 3     Protein Associated With Small Stress Protein 13
HSPB (Heat Shock 27kD) Associated Protein 11     

External Ids:    HGNC: 163891   Entrez Gene: 796632   Ensembl: ENSG000001690877   OMIM: 6082635   UniProtKB: Q96EW23   

Export aliases for HSPBAP1 gene to outside databases

Previous GC identifers: GC03M119179 GC03M123740 GC03M123779 GC03M123941 GC03M119832


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HSPBAP1 Gene:
This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is
involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in
patients with intractable epilepsy, although how brain function is affected remains unknown. (provided by RefSeq,
Sep 2011)

GeneCards Summary for HSPBAP1 Gene:
HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1) is a protein-coding gene. Diseases associated with HSPBAP1 include familial renal cell carcinoma, and tonsillitis. An important paralog of this gene is TYW5.

UniProtKB/Swiss-Prot: HBAP1_HUMAN, Q96EW2
Function: May play a role in cellular stress response (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HSPBAP1 gene promoter:
         C/EBPbeta   p53   POU3F2   GATA-1   c-Ets-1   Evi-1   AREB6   HEN1   FAC1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHSPBAP1 promoter sequence
   Search Chromatin IP Primers for HSPBAP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSPBAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.1   Ensembl cytogenetic band:  3q21.1   HGNC cytogenetic band: 3q21.1

HSPBAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPBAP1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M122407:  view genomic region     (about GC identifiers)

Start:
122,458,846 bp from pter      End:
122,512,671 bp from pter
Size:
53,826 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: HBAP1_HUMAN, Q96EW2 (See protein sequence)
Recommended Name: HSPB1-associated protein 1  
Size: 488 amino acids; 55167 Da
Subunit: Interacts with CRYAB and HSPB1
Sequence caution: Sequence=AAH17763.1; Type=Erroneous initiation;
Secondary accessions: Q6P476 Q8N8J4 Q8NHH6 Q8WWF0
Alternative splicing: 3 isoforms:  Q96EW2-1   Q96EW2-2   Q96EW2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for HSPBAP1: NX_Q96EW2

Explore proteomics data for HSPBAP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HSPBAP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078886.2  
    ENSEMBL proteins: 
     ENSP00000302562   ENSP00000373155  

    HSPBAP1 Human Recombinant Protein Products:

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    Novus Biologicals HSPBAP1 Protein
    Novus Biologicals HSPBAP1 Lysates
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    ProSpec Recombinant Protein for HSPBAP1
    Cloud-Clone Corp. Proteins for HSPBAP1

    HSPBAP1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search for Antibodies for HSPBAP1 at Abcam
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    ThermoFisher Antibody for HSPBAP1
    LSBio Antibodies in human, mouse, rat for HSPBAP1

    HSPBAP1 Assay Products:

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    Cloud-Clone Corp. ELISAs for HSPBAP1
    Cloud-Clone Corp. CLIAs for HSPBAP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR013296 HSPB1-associated_protein_1
     IPR003347 JmjC_dom

    Graphical View of Domain Structure for InterPro Entry Q96EW2

    ProtoNet protein and cluster: Q96EW2

    1 Blocks protein domain: IPB003347 Transcription factor jumonji

    UniProtKB/Swiss-Prot: HBAP1_HUMAN, Q96EW2
    Similarity: Contains 1 JmjC domain


    HSPBAP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HBAP1_HUMAN, Q96EW2
    Function: May play a role in cellular stress response (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    HSPBAP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HSPBAP1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HSPBAP1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HSPBAP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HSPBAP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HSPBAP1

    miRNA
    Products:
        
    miRTarBase miRNAs that target HSPBAP1:
    hsa-mir-215-5p (MIRT024673), hsa-mir-192-5p (MIRT026793)

    Block miRNA regulation of human, mouse, rat HSPBAP1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate HSPBAP1:
    hsa-miR-485-5p
    SwitchGear 3'UTR luciferase reporter plasmidHSPBAP1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HSPBAP1
    Predesigned siRNA for gene silencing in human, mouse, rat HSPBAP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HSPBAP1

    Clone
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    OriGene clones in human, mouse for HSPBAP1 (see all 8)
    OriGene ORF clones in mouse, rat for HSPBAP1
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    GenScript: all cDNA clones in your preferred vector: HSPBAP1 (NM_024610)
    Sino Biological Human cDNA Clone for HSPBAP1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPBAP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPBAP1

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPBAP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    HBAP1_HUMAN, Q96EW2: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    HSPBAP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including HSPBAP1: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for HSPBAP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for HSPBAP1 (Q96EW22, 3 ENSP000003025624) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTNP212462, 3MINT-65014 I2D: score=5 
    TK1P041832, 3MINT-8273543 I2D: score=2 
    KAT2AQ928303I2D: score=1 
    SDE2ENSP000002720914STRING: ENSP00000272091
    NME1ENSP000000130344STRING: ENSP00000013034
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HSPBAP1 (HBAP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HSPBAP1 gene: 
    NM_024610.5  

    Unigene Cluster for HSPBAP1:

    HSPB (heat shock 27kDa) associated protein 1
    Hs.29169  [show with all ESTs]
    Unigene Representative Sequence: AK096705
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000471534(uc003eft.2) ENST00000306103(uc003efu.2) ENST00000465044
    ENST00000467643 ENST00000478601 ENST00000463266 ENST00000383659(uc003efv.2)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HSPBAP1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate HSPBAP1:
    hsa-miR-485-5p
    SwitchGear 3'UTR luciferase reporter plasmidHSPBAP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HSPBAP1
    Predesigned siRNA for gene silencing in human, mouse, rat HSPBAP1
    Clone
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    OriGene clones in human, mouse for HSPBAP1 (see all 8)
    OriGene ORF clones in mouse, rat for HSPBAP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HSPBAP1 (NM_024610)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPBAP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPBAP1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for HSPBAP1
    OriGene qSTAR qPCR primer pairs in human, mouse for HSPBAP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HSPBAP1
      QuantiTect SYBR Green Assays in human, mouse, rat HSPBAP1
      QuantiFast Probe-based Assays in human, mouse, rat HSPBAP1

    Additional mRNA sequence: 

    AF400663.1 AK026276.1 AK096705.1 AK289410.1 BC011897.2 BC017763.1 BC063629.1 

    4 DOTS entries:

    DT.313932  DT.100747296  DT.95253649  DT.100679139 

    Selected AceView cDNA sequences (see all 108):

    BQ013958 BM975491 BC011897 AI867878 CR598288 AL543460 AI985348 AW243355 
    BU630355 CR617201 AI432143 AA909433 BM987235 BU194167 AK026276 AA776877 
    BM742997 CA312747 AA812771 BQ574164 BM989184 BU753569 BM558864 NM_024610 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HSPBAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACATTCCTC
    HSPBAP1 Expression
    About this image


    HSPBAP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Heart (Cardiovascular System)
             Cushion Mesenchymal Cells Endocardium
     
     Ovary (Reproductive System)
             Oviduct
    HSPBAP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HSPBAP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.29169

    UniProtKB/Swiss-Prot: HBAP1_HUMAN, Q96EW2
    Tissue specificity: Widely expressed

        Pathway & Disease-focused RT2 Profiler PCR Arrays including HSPBAP1: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for HSPBAP1
    OriGene qSTAR qPCR primer pairs in human, mouse for HSPBAP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HSPBAP1
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    QuantiFast Probe-based Assays in human, mouse, rat HSPBAP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPBAP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for HSPBAP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hspbap11 , 5 Hspb associated protein 11, 5 78.29(n)1
    73.7(a)1
      16 (25.43 cM)5
    666671  NM_175111.31  NP_780320.21 
     357703865 
    chicken
    (Gallus gallus)
    Aves HSPBAP11 HSPB (heat shock 27kDa) associated protein 1 68.05(n)
    62.45(a)
      424245  XM_004942926.1  XP_004942983.1 
    lizard
    (Anolis carolinensis)
    Reptilia HSPBAP16
    HSPB (heat shock 27kDa) associated protein 1
    54(a)
    1 ↔ 1
    1(83399536-83470393)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.208282 Xenopus laevis transcribed sequence 81.47(n)    BQ884385.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hspbap11 hspb associated protein 1 57.29(n)
    53.02(a)
      445320  NM_001003777.2  NP_001003777.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG433206
    --
    23(a)
    1 ↔ 1
    3R(23520977-23522173)


    ENSEMBL Gene Tree for HSPBAP1 (if available)
    TreeFam Gene Tree for HSPBAP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HSPBAP1 gene
    TYW52  KDM82  HIF1AN2  

    HSPBAP1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for HSPBAP1
    PGOHUM00000247588


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HSPBAP1 (see all 1060)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1908430991,2
    C--119831635(+) ATGCAC/TGGTTA 1 -- int10--------
    rs1475397591,2
    C--119831665(+) TTCTAA/TTTTCT 1 -- int10--------
    rs1394274121,2
    --119831776(+) TTGGGA/GAGTTT 1 -- int10--------
    rs1450071521,2
    --119831780(+) GGAGTC/TTGAGT 1 -- int10--------
    rs1835521731,2
    --119831820(+) GATGTC/GCAAGT 1 -- int10--------
    rs1126042921,2
    F--119831876(+) CCTGAC/TTGGTA 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1395119641,2
    --119831927(+) CAGCTA/GTTACA 1 -- int10--------
    rs1874825001,2
    --119831951(+) CAGAGC/TGAGGC 1 -- int10--------
    rs1143299511,2
    C,F--119831995(+) AGGCTG/AACAAA 1 -- int11Minor allele frequency- A:0.03NA 120
    rs1153996641,2
    C,F--119832047(+) CCATAC/TACTCT 1 -- int11Minor allele frequency- T:0.03NA 120

    HapMap Linkage Disequilibrium report for HSPBAP1 (122458846 - 122512671 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for HSPBAP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1422853CNV Deletion17803354
    nsv3975CNV Loss18451855
    nsv829705CNV Loss17160897
    nsv822228CNV Loss20364138
    nsv877391CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HSPBAP1
    DNA2.0 Custom Variant and Variant Library Synthesis for HSPBAP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608263    OMIM disorders: --

    UniProtKB/Swiss-Prot: HBAP1_HUMAN, Q96EW2
  • Note=A chromosomal aberration involving HSPBAP1 has been found in a family with renal carcinoma.
    Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces a hybrid mRNA encoding a truncated
    HSPBAP1 lacking the first 36 amino acids

  • 8 diseases for HSPBAP1:    
    About MalaCards
    familial renal cell carcinoma    tonsillitis    multiple myeloma    myeloma
    thyroiditis    cerebritis    endotheliitis    prostatitis


    HSPBAP1 for disorders           About GeneDecksing


    Export disorders for HSPBAP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HSPBAP1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with HSPBAP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of a novel human gene (HSPBAP1) from human fetal brain. (PubMed id 11978969)1, 2, 3, 9 Jiang M.... Mao Y. (Cytogenet. Cell Genet. 2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    4. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    5. HSPBAP1 is found extensively in the anterior temporal neocortex of patients with intractable epilepsy. (PubMed id 17568411)1 Xi Z.Q....Guan L.F. (Synapse 2007)
    6. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAP1 fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21). (PubMed id 12939738)2 Bodmer D....Geurts van Kessel A. (Genes Chromosomes Cancer 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27. (PubMed id 10751411)2 Liu C.... Welsh M.J. (J. Biol. Chem. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79663 HGNC: 16389 AceView: HSPBAP1 Ensembl:ENSG00000169087 euGenes: HUgn79663
    ECgene: HSPBAP1 H-InvDB: HSPBAP1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HSPBAP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for HSPBAP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HSPBAP1 gene:
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