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Aliases for HSPB2-C11orf52 Gene

Subcategory (RNA class) for HSPB2-C11orf52 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for HSPB2-C11orf52 Gene

  • HSPB2-C11orf52 Readthrough (NMD Candidate) 2 3 5

External Ids for HSPB2-C11orf52 Gene

Previous GeneCards Identifiers for HSPB2-C11orf52 Gene

  • GC11U901862
  • GC11P111785

Summaries for HSPB2-C11orf52 Gene

Entrez Gene Summary for HSPB2-C11orf52 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring heat shock 27kDa protein 2 (HSPB2) and chromosome 11 open reading frame 52 (C11orf52) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) based on the use of the supported HSPB2 translational start codon, and it is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for HSPB2-C11orf52 Gene

HSPB2-C11orf52 (HSPB2-C11orf52 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include enzyme activator activity. An important paralog of this gene is HSPB6.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSPB2-C11orf52 Gene

Genomics for HSPB2-C11orf52 Gene

Regulatory Elements for HSPB2-C11orf52 Gene


Promoters for HSPB2-C11orf52 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around HSPB2-C11orf52 on UCSC Golden Path with GeneCards custom track

Genomic Location for HSPB2-C11orf52 Gene

Chromosome:
11
Start:
111,912,736 bp from pter
End:
111,926,871 bp from pter
Size:
14,136 bases
Orientation:
Plus strand

Genomic View for HSPB2-C11orf52 Gene

Genes around HSPB2-C11orf52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSPB2-C11orf52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSPB2-C11orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSPB2-C11orf52 Gene

Proteins for HSPB2-C11orf52 Gene

  • Protein details for HSPB2-C11orf52 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A8KAH6
    Recommended name:
    Heat shock 27kDa protein 2, isoform CRA_a
    Protein Accession:
    A8KAH6

    Protein attributes for HSPB2-C11orf52 Gene

    Size:
    182 amino acids
    Molecular mass:
    20233 Da
    Quaternary structure:
    No Data Available
  • Protein details for HSPB2-C11orf52 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E9PN16
    Recommended name:
    Protein HSPB2-C11orf52
    Protein Accession:
    E9PN16

    Protein attributes for HSPB2-C11orf52 Gene

    Size:
    52 amino acids
    Molecular mass:
    5934 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSPB2-C11orf52 Gene

Proteomics data for HSPB2-C11orf52 Gene at MOPED

Protein Expression for HSPB2-C11orf52 Gene

Post-translational modifications for HSPB2-C11orf52 Gene

No Post-translational modifications

Other Protein References for HSPB2-C11orf52 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for HSPB2-C11orf52 Gene

Domains & Families for HSPB2-C11orf52 Gene

Protein Domains for HSPB2-C11orf52 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HSPB2-C11orf52: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HSPB2-C11orf52 Gene

Function for HSPB2-C11orf52 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSPB2-C11orf52 Gene

Localization for HSPB2-C11orf52 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HSPB2-C11orf52 Gene COMPARTMENTS Subcellular localization image for HSPB2-C11orf52 gene
Compartment Confidence
cytosol 5
nucleus 5
cytoskeleton 3
extracellular 2
mitochondrion 2
plasma membrane 2
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for HSPB2-C11orf52 Gene

Pathways & Interactions for HSPB2-C11orf52 Gene

SuperPathways for HSPB2-C11orf52 Gene

No Data Available

Interacting Proteins for HSPB2-C11orf52 Gene

Gene Ontology (GO) - Biological Process for HSPB2-C11orf52 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HSPB2-C11orf52 Gene

Drugs & Compounds for HSPB2-C11orf52 Gene

No Compound Related Data Available

Transcripts for HSPB2-C11orf52 Gene

mRNA/cDNA for HSPB2-C11orf52 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for HSPB2-C11orf52 Gene

No ASD Table

Relevant External Links for HSPB2-C11orf52 Gene

GeneLoc Exon Structure for
HSPB2-C11orf52
ECgene alternative splicing isoforms for
HSPB2-C11orf52

Expression for HSPB2-C11orf52 Gene

Protein differential expression in normal tissues from HIPED for HSPB2-C11orf52 Gene

This gene is overexpressed in Fetal heart (26.4), Tonsil (20.0), and Heart (12.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb and MaxQB for HSPB2-C11orf52 Gene



Protein tissue co-expression partners for HSPB2-C11orf52 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HSPB2-C11orf52 Gene

Orthologs for HSPB2-C11orf52 Gene

This gene was present in the common ancestor of animals.

Orthologs for HSPB2-C11orf52 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia HSPB2 36
  • 98 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 96 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 90 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Hspb2 36
  • 97 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
chicken
(Gallus gallus)
Aves HSPB2 36
  • 57 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 59 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii hspb2 36
  • 50 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG13133 36
  • 18 (a)
ManyToMany
CG14207 36
  • 19 (a)
ManyToMany
CG4461 36
  • 20 (a)
ManyToMany
CG7409 36
  • 25 (a)
ManyToMany
Hsp22 36
  • 21 (a)
ManyToMany
Hsp23 36
  • 25 (a)
ManyToMany
Hsp26 36
  • 21 (a)
ManyToMany
Hsp27 36
  • 23 (a)
ManyToMany
Hsp67Ba 36
  • 11 (a)
ManyToMany
Hsp67Bc 36
  • 21 (a)
ManyToMany
l(2)efl 36
  • 28 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea F08H9.3 36
  • 20 (a)
ManyToMany
F08H9.4 36
  • 29 (a)
ManyToMany
hsp-12.1 36
  • 28 (a)
ManyToMany
hsp-12.2 36
  • 30 (a)
ManyToMany
hsp-12.3 36
  • 22 (a)
ManyToMany
hsp-12.6 36
  • 26 (a)
ManyToMany
hsp-16.1 36
  • 25 (a)
ManyToMany
hsp-16.11 36
  • 25 (a)
ManyToMany
hsp-16.2 36
  • 25 (a)
ManyToMany
hsp-16.41 36
  • 23 (a)
ManyToMany
hsp-16.48 36
  • 24 (a)
ManyToMany
hsp-16.49 36
  • 24 (a)
ManyToMany
hsp-17 36
  • 23 (a)
ManyToMany
hsp-25 36
  • 17 (a)
ManyToMany
hsp-43 36
  • 9 (a)
ManyToMany
sip-1 36
  • 19 (a)
ManyToMany
Y55F3BR.6 36
  • 22 (a)
ManyToMany
Species with no ortholog for HSPB2-C11orf52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for HSPB2-C11orf52 Gene

ENSEMBL:
Gene Tree for HSPB2-C11orf52 (if available)
TreeFam:
Gene Tree for HSPB2-C11orf52 (if available)

Paralogs for HSPB2-C11orf52 Gene

Paralogs for HSPB2-C11orf52 Gene

genes like me logo Genes that share paralogs with HSPB2-C11orf52: view

Variants for HSPB2-C11orf52 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for HSPB2-C11orf52 Gene

Disorders for HSPB2-C11orf52 Gene

Relevant External Links for HSPB2-C11orf52

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSPB2-C11orf52

No disorders were found for HSPB2-C11orf52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSPB2-C11orf52 Gene

Publications for HSPB2-C11orf52 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for HSPB2-C11orf52 Gene

Sources for HSPB2-C11orf52 Gene

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