Aliases for HSPB2 Gene
External Ids for HSPB2 Gene
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012]
GeneCards Summary for HSPB2 Gene
HSPB2 (Heat Shock 27kDa Protein 2) is a Protein Coding gene. Diseases associated with HSPB2 include prostate cancer and glioblastoma multiforme. Among its related pathways are Proteoglycans in cancer and Epstein-Barr virus infection. GO annotations related to this gene include enzyme activator activity. An important paralog of this gene is CRYAA.
UniProtKB/Swiss-Prot for HSPB2 Gene
May regulate the kinase DMPK.