Aliases for HSPB2 Gene
External Ids for HSPB2 Gene
Previous GeneCards Identifiers for HSPB2 Gene
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012]
GeneCards Summary for HSPB2 Gene
HSPB2 (Heat Shock Protein Family B (Small) Member 2) is a Protein Coding gene. Diseases associated with HSPB2 include Corticobasal Degeneration and Charcot-Marie-Tooth Disease, Axonal, Type 2L. Among its related pathways are MAPK signaling pathway and IL-1 signaling pathway. GO annotations related to this gene include enzyme activator activity. An important paralog of this gene is HSPB2-C11orf52.
UniProtKB/Swiss-Prot for HSPB2 Gene
May regulate the kinase DMPK.