Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



HSPB11 Gene

protein-coding   GIFtS: 45
GCID: GC01M054387

Heat Shock Protein Family B (Small), Member 11

(Previous name: chromosome 1 open reading frame 41)
(Previous symbol: C1orf41)
  Search for HSPB11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Heat Shock Protein Family B (Small), Member 111 2     Chromosome 1 Open Reading Frame 411
C1orf411 2 3     Intraflagellar Transport 25 Homolog (Chlamydomonas)1
Heat Shock Protein Beta-112 3     HSPCO342
Placental Protein 252 3     Intraflagellar Transport 25 Homolog2
IFT252 3     Intraflagellar Transport Protein 25 Homolog2
PP252 3     Hspb113

External Ids:    HGNC: 250191   Entrez Gene: 516682   Ensembl: ENSG000000818707   UniProtKB: Q9Y5473   

Export aliases for HSPB11 gene to outside databases

Previous GC identifers: GC01M054159 GC01M052502


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for HSPB11 Gene:
HSPB11 (heat shock protein family B (small), member 11) is a protein-coding gene.

UniProtKB/Swiss-Prot: IFT25_HUMAN, Q9Y547
Function: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH
components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at
the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport
of SHH signaling molecules within the cilium. Not required for ciliary assembly (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HSPB11 gene promoter:
         AhR   TBP   MIF-1   GATA-1   HNF-1A   MZF-1   HNF-1   TFIID   STAT3   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHSPB11 promoter sequence
   Search Chromatin IP Primers for HSPB11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSPB11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32

HSPB11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPB11 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M054387:  view genomic region     (about GC identifiers)

Start:
54,382,247 bp from pter      End:
54,411,602 bp from pter
Size:
29,356 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: IFT25_HUMAN, Q9Y547 (See protein sequence)
Recommended Name: Intraflagellar transport protein 25 homolog  
Size: 144 amino acids; 16297 Da
Subunit: Component of the IFT complex B, at least composed of IFT20, IFT25/HSPB11, IFT27, IFT52, IFT57, IFT74,
IFT81, IFT88 and TRAF3IP1. Interacts with IFT27; the interaction is direct (By similarity)
Caution: Was initially classified as a member of the small heat shock family protein. However, it was later shown
that it is not the case
Sequence caution: Sequence=AAD43011.1; Type=Frameshift; Positions=77;
2 PDB 3D structures from and Proteopedia for HSPB11:
1TVG (3D)        1XPW (3D)    
Secondary accessions: A6NG57 D3DQ45 Q9Y684

Explore the universe of human proteins at neXtProt for HSPB11: NX_Q9Y547

Explore proteomics data for HSPB11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HSPB11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057210.2  
    ENSEMBL proteins: 
     ENSP00000360429   ENSP00000194214   ENSP00000360428   ENSP00000360427  

    HSPB11 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for HSPB11
    OriGene Protein Over-expression Lysate for HSPB11
    OriGene MassSpec for HSPB11
    OriGene Custom Protein Services for HSPB11
    GenScript Custom Purified and Recombinant Proteins Services for HSPB11
    Novus Biologicals HSPB11 Proteins
    Novus Biologicals HSPB11 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for HSPB11
    Browse Proteins at Cloud-Clone Corp.

    HSPB11 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for HSPB11
    Novus Biologicals HSPB11 Antibody
    Abcam antibodies for HSPB11
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for HSPB11
    LSBio Antibodies in human, mouse, rat for HSPB11

    HSPB11 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HSPB11
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HSPB11
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    HSPB: Heat shock proteins / HSPB
    IFT: Intraflagellar transport homologs

    2 InterPro protein domains:
     IPR008979 Galactose-bd-like
     IPR000421 Coagulation_fac_5/8-C_type_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y547

    ProtoNet protein and cluster: Q9Y547

    UniProtKB/Swiss-Prot: IFT25_HUMAN, Q9Y547
    Similarity: Belongs to the IFT25 family


    HSPB11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IFT25_HUMAN, Q9Y547
    Function: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH
    components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at
    the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport
    of SHH signaling molecules within the cilium. Not required for ciliary assembly (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    HSPB11 for ontologies           About GeneDecksing


    Phenotypes:
         11 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Hspb11):
     cardiovascular system  craniofacial  digestive/alimentary  embryogenesis  growth/size/body 
     homeostasis/metabolism  limbs/digits/tail  mortality/aging  nervous system  respiratory system 
     skeleton 

    HSPB11 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HSPB11
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HSPB11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HSPB11
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HSPB11

    miRNA
    Products:
        
    miRTarBase miRNAs that target HSPB11:
    hsa-mir-155-5p (MIRT020507)

    Block miRNA regulation of human, mouse, rat HSPB11 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate HSPB11:
    hsa-miR-548l
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for HSPB11
    Predesigned siRNA for gene silencing in human, mouse, rat HSPB11

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HSPB11

    Clone
    Products:
         
    OriGene clones in human, mouse for HSPB11 (see all 8)
    OriGene ORF clones in mouse, rat for HSPB11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HSPB11 (NM_016126)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPB11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for HSPB11
    Browse ESI BIO Cell Lines and PureStem Progenitors for HSPB11 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPB11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005929cilium IEA--
    GO:0030992intraciliary transport particle B IEA--

    HSPB11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HSPB11
    Interactions:

        Search GeneGlobe Interaction Network for HSPB11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for HSPB11 (Q9Y5472, 3 ENSP000001942144) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IFT27Q9BW832, 3, ENSP000003435934MINT-66983 I2D: score=5 STRING: ENSP00000343593
    VHLP403373, ENSP000002564744I2D: score=1 STRING: ENSP00000256474
    NUP62P371983I2D: score=1 
    APBB1IPENSP000003654114STRING: ENSP00000365411
    EIF4G3ENSP000002642114STRING: ENSP00000264211
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006950response to stress IEA--
    GO:0007155cell adhesion IEA--
    GO:0015031protein transport IEA--
    GO:0042384NOT cilium assembly ISS--

    HSPB11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HSPB11 (IFT25)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for HSPB11 gene: 
    NM_016126.2  

    Unigene Clusters for HSPB11:

    Heat shock protein family B (small), member 11
    Hs.525462  [show with all ESTs], Hs.624686
    Unigene Representative Sequences: AK128270, BC045699
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371378 ENST00000194214(uc001cwh.3) ENST00000489675 ENST00000371377(uc001cwi.1)
    ENST00000371376 ENST00000488884
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat HSPB11 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate HSPB11:
    hsa-miR-548l
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for HSPB11
    Predesigned siRNA for gene silencing in human, mouse, rat HSPB11
    Clone
    Products:
         
    OriGene clones in human, mouse for HSPB11 (see all 8)
    OriGene ORF clones in mouse, rat for HSPB11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: HSPB11 (NM_016126)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPB11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for HSPB11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HSPB11
      QuantiTect SYBR Green Assays in human, mouse, rat HSPB11
      QuantiFast Probe-based Assays in human, mouse, rat HSPB11

    Additional mRNA sequence: BC045699.1 

    10 DOTS entries:

    DT.414964  DT.95150389  DT.100815258  DT.40118380  DT.95194110  DT.121446093  DT.95266413  DT.91762003 
    DT.95266414  DT.97861827 

    Selected AceView cDNA sequences (see all 137):

    AF417114 AI457741 BM873908 AI343642 BC045699 BM663914 AF416725 BC005245 
    BP428737 BI962611 CB136468 AW024033 BM709120 AI828424 BP430126 BM705111 
    BM874677 AA280409 N52699 AI342582 AI581322 AI140006 AI760192 BG183429 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for HSPB11 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c
    SP1:              -     -     -           -           -                       -     -                     
    SP2:                                      -                                                               
    SP3:                                      -           -                       -     -                     
    SP4:              -     -     -           -           -                                                   
    SP5:                                      -           -                                                   


    ECgene alternative splicing isoforms for HSPB11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    HSPB11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTTTTAAC
    HSPB11 Expression
    About this image

    HSPB11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HSPB11 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.525462 Hs.624686

    UniProtKB/Swiss-Prot: IFT25_HUMAN, Q9Y547
    Tissue specificity: Detected in placenta

        Custom PCR Arrays for HSPB11
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for HSPB11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HSPB11
    QuantiTect SYBR Green Assays in human, mouse, rat HSPB11
    QuantiFast Probe-based Assays in human, mouse, rat HSPB11
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPB11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for HSPB11 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hspb111 , 5 heat shock protein family B (small), member 111, 5 86.85(n)1
    85.92(a)1
      4 (50.18 cM)5
    729381  NM_028394.21  NP_082670.11 
     1072535935 
    chicken
    (Gallus gallus)
    Aves HSPB111 heat shock protein family B (small), member 11 66.67(n)
    65.22(a)
      424654  NM_001277613.1  NP_001264542.1 
    lizard
    (Anolis carolinensis)
    Reptilia HSPB116
    heat shock protein family B (small), member 11
    64(a)
    1 ↔ 1
    4(115863530-115870590)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.5412 Transcribed sequence with weak similarity to protein more 80.62(n)    142034388 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1586401 zgc:158640 58.08(n)
    50.76(a)
      790918  NM_001080065.1  NP_001073534.1 


    ENSEMBL Gene Tree for HSPB11 (if available)
    TreeFam Gene Tree for HSPB11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for HSPB11 (see all 464)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1383536451,2
    --54386918(+) CTCAGC/TGAAAC 1 -- ds50010--------
    rs1180335711,2
    C,F--54387010(+) ATCAAT/CTAAAA 1 -- ds50011Minor allele frequency- C:0.02EA 120
    rs1918085831,2
    --54387029(+) CACTAC/TGATCT 1 -- ds50010--------
    rs1496374001,2
    C--54387288(+) AATATA/GTTGTT 1 -- ut310--------
    rs1443418491,2
    C--54387327(+) CATTAC/TGAGGA 2 S syn10--------
    rs1401036851,2
    C--54387395(+) AAAGGC/TTGATA 2 T A mis10--------
    rs1840498121,2
    --54387425(+) AGTAGC/TGGAGC 2 T A mis10--------
    rs1154366551,2
    C--54387445(+) CCTGTA/TTGGGA 1 -- int12Minor allele frequency- T:0.00WA EU 1435
    rs120907891,2
    C,F,H--54387577(+) TATAAT/CAGTTG 1 -- int120Minor allele frequency- C:0.26NS EA NA WA CSA 2346
    rs1875180511,2
    --54387637(+) TGGAGC/GTAAAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for HSPB11 (54382247 - 54411602 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for HSPB11: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HSPB11
    DNA2.0 Custom Variant and Variant Library Synthesis for HSPB11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for HSPB11 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with HSPB11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    2. Characterization of mouse IFT complex B. (PubMed id 19253336)1, 3 Follit J.A....Pazour G.J. (Cell Motil. Cytoskeleton 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Isolation and characterization of five new soluble placental tissue proteins (PP22, PP23, PP24, PP25, PP26). (PubMed id 2018407)1, 2 Bohn H. and Winckler W. (Arch. Gynecol. Obstet. 1991)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. (PubMed id 18816799)2 Ramelot T.A.... Kennedy M.A. (Proteins 2009)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors. (PubMed id 18154656)1 Pozsgai E....Bellyei S. (BMC Cancer 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51668 HGNC: 25019 AceView: C1orf41 Ensembl:ENSG00000081870 euGenes: HUgn51668
    ECgene: HSPB11 H-InvDB: HSPB11

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for HSPB11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for HSPB11 gene:
    Search GeneIP for patents involving HSPB11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for HSPB11  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for HSPB11  
     OriGene MassSpec something-or-other for HSPB11   OriGene clones in human, mouse for HSPB11  
     OriGene qSTAR qPCR primer pairs in human, mouse for HSPB11   OriGene Purified Protein for HSPB11  
     OriGene ORF clones in mouse, rat for HSPB11   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for HSPB11   OriGene Custom Protein Services for HSPB11  

     
     
     Block miRNA regulation of human, mouse, rat HSPB11 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing HSPB11
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSPB11 Predesigned siRNA for gene silencing in human, mouse, rat HSPB11
     QuantiFast Probe-based Assays in human, mouse, rat HSPB11 QuantiTect SYBR Green Assays in human, mouse, rat HSPB11
     Custom PCR Arrays for HSPB11 Search Chromatin IP Primers for HSPB11
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat HSPB11  Search GeneGlobe Interaction Network for HSPB11
     Regulatory tfbs in HSPB11 promoter
     GenScript Custom Purified and Recombinant Proteins Services for HSPB11 GenScript cDNA clones with any tag delivered in your preferred vector for HSPB11
     GenScript Custom Assay Services for HSPB11 GenScript Custom overexpressing Cell Line Services for HSPB11
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for HSPB11 (IFT25)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     HSPB11 antibodies
     HSPB11 proteins
     HSPB11 lysates
     Antibodies for HSPB11
     See all of Abcam's Antibodies, Kits and Proteins for HSPB11
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for HSPB11
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for HSPB11
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPB11
     Browse SwitchGear 3'UTR luciferase reporter plasmids for HSPB11
     SwitchGear Promoter luciferase reporter plasmids for HSPB11
     ThermoFisher Antibody for HSPB11
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HSPB11
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for HSPB11
     LSBio Antibodies in human, mouse, rat for HSPB11
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      HSPB11 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4