Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

HSPB11 Gene

protein-coding GIFtS: 44
GCID: GC01M054387

heat shock protein family B (small), member 11

(Previous name: chromosome 1 open reading frame 41 )
(Previous symbol: C1orf41)

Search for HSPB11
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Heat Shock Protein Family B (Small), Member 11¹ ²		Placental Protein 25² ³
C1orf41¹ ² ³		Chromosome 1 Open Reading Frame 41¹
PP25¹ ² ³		Heat Shock Protein Beta-11²
HSPCO34¹ ²		Intraflagellar Transport 25 Homolog²
IFT25¹ ²		Hspb11³

External Ids:	HGNC: 25019¹	Entrez Gene: 51668²	Ensembl: ENSG00000081870⁷	UniProtKB: Q9Y547³

Export aliases for HSPB11 gene to outside databases

Previous GC identifers: GC01M054159 GC01M052502

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HSPB11 gene promoter:
AhR TBP MIF-1 GATA-1 HNF-1A MZF-1 HNF-1 TFIID STAT3 ZID
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HSPB11 promoter sequence

Search SABiosciences Chromatin IP Primers for HSPB11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPB11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32 Ensembl cytogenetic band: 1p32.3 HGNC cytogenetic band: 1p32

HSPB11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPB11 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M054387: view genomic region (about GC identifiers)

Start:	54,387,234 bp from pter	End:	54,411,975 bp from pter
Size:	24,742 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HSB11_HUMAN, Q9Y547 (See protein sequence)

Recommended Name: Heat shock protein beta-11

Size: 144 amino acids; 16297 Da

Subunit: Component of IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20 (By similarity)

Sequence caution: Sequence=AAD43011.1; Type=Frameshift; Positions=77;

2 PDB 3D structures from and Proteopedia for HSPB11:

1TVG (3D)

1XPW (3D)

Secondary accessions: A6NG57 D3DQ45 Q9Y684

Explore the universe of human proteins at neXtProt for HSPB11: NX_Q9Y547

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y547

HSPB11 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_057210.2

ENSEMBL proteins:

ENSP00000194214 ENSP00000360429 ENSP00000360428 ENSP00000360427

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: HSPB11 OriGene Protein Over-expression Lysate: HSPB11 OriGene Custom Protein Services for HSPB11
	GenScript Custom Purified and Recombinant Proteins Services for HSPB11
	Novus Biologicals HSPB11 Proteins Novus Biologicals HSPB11 Lysate
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for HSPB11
	Browse Proteins at Uscn

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005929	cilium	IEA	--
GO:0030992	intraflagellar transport particle B	IEA	--

HSPB11 for ontologies About GeneDecksing

HSPB11 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for HSPB11
	GenScript Custom Superior Antibodies Services for HSPB11
	Novus Biologicals HSPB11 Antibody
	Abcam antibodies for HSPB11
	Browse Antibodies at Uscn
	ThermoFisher Antibody for HSPB11

Assay Products for HSPB11:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for HSPB11
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HSPB11 for domains About GeneDecksing

2 InterPro domains/families:

IPR008979 Galactose-bd-like

IPR000421 Coagulation_fac_5/8-C_type_dom

Graphical View of Domain Structure for InterPro Entry Q9Y547

ProtoNet protein and cluster: Q9Y547

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: HSPB11 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPB11
		1 QIAGEN miScript miRNA Assays for microRNA that regulate HSPB11:
		hsa-miR-548l
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPB11 (see all 3) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPB11

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for HSPB11

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HSPB11 (NM_016126)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPB11
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HSPB11
		Search LifeMap BioReagents cell lines for HSPB11

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for HSPB11

Animal Models:
11 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Hspb11):

cardiovascular system	craniofacial	digestive/alimentary	embryogenesis	growth/size
homeostasis/metabolism	limbs/digits/tail	mortality/aging	nervous system	respiratory system
skeleton

HSPB11 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for HSPB11

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

5/12 Interacting proteins for HSPB11 (Q9Y547^{2, 3} ENSP00000194214⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IFT27	Q9BW83²^,³, ENSP00000343593⁴	MINT-66983 I2D: score=5 STRING: ENSP00000343593
VHL	P40337³, ENSP00000256474⁴	I2D: score=1 STRING: ENSP00000256474
NUP62	P37198³	I2D: score=1
APBB1IP	ENSP00000365411⁴	STRING: ENSP00000365411
EIF4G3	ENSP00000264211⁴	STRING: ENSP00000264211

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006950	response to stress	IEA	--
GO:0007155	cell adhesion	IEA	--

HSPB11 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HSPB11
Search CenterWatch for drugs/clinical trials and news about HSPB11 / HSB11

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HSPB11 gene:

NM_016126.2

Unigene Clusters for HSPB11:

Heat shock protein family B (small), member 11

Hs.525462 [show with all ESTs], Hs.624686

Unigene Representative Sequences: AK128270, BC045699

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000194214(uc001cwh.3) ENST00000489675 ENST00000371378 ENST00000371377(uc001cwi.1)

ENST00000371376 ENST00000488884

miRNA Products:		OriGene 3'-UTR Clone: HSPB11 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPB11
		1 QIAGEN miScript miRNA Assays for microRNA that regulate HSPB11:
		hsa-miR-548l
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPB11 (see all 3) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPB11

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HSPB11 (NM_016126)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPB11
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPB11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSPB11
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPB11
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPB11

Additional cDNA sequence: BC045699.1

10 DOTS entries:

DT.414964 DT.95150389 DT.100815258 DT.40118380 DT.95194110 DT.121446093 DT.95266413 DT.91762003

DT.95266414 DT.97861827

24/137 AceView cDNA sequences (see all 137):

BM873908 BM709120 AF416725 N52699 AI828424 AI581322 BC005245 AI140006

BI962611 BP430126 AW024033 AI342582 BM705111 BP428737 AI343642 AF417114

AI457741 AA280409 CB136468 BC045699 BM663914 BM874677 BI789139 AI193596

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for HSPB11 (see all 7) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	·	7c	·	7d	^	8a	·	8b	·	8c
SP1:					-		-		-				-				-								-		-
SP2:													-
SP3:													-				-								-		-
SP4:					-		-		-				-				-
SP5:													-				-

ECgene alternative splicing isoforms for HSPB11

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HSPB11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTTTTTAAC

About this image

HSPB11 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Right Ventricle

Heart

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See HSPB11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSPB11

SOURCE GeneReport for Unigene clusters: Hs.525462 Hs.624686

UniProtKB/Swiss-Prot: HSB11_HUMAN, Q9Y547

Tissue specificity: Detected in placenta

SABiosciences Custom PCR Arrays for HSPB11

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPB11 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSPB11
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPB11
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPB11

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for HSPB11

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for HSPB11 gene from 4/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Details
mouse (Mus musculus)	Mammalia	Hspb11^{1 , 5}	heat shock protein family B (small), member 11^{1, 5}	86.85(n)¹ 85.92(a)¹	4 (50.18 cM)⁵ 72938¹ NM_028394.2¹ NP_082670.1¹ 107253593⁵
chicken (Gallus gallus)	Aves	HSPB11¹	heat shock protein family B (small), member 11	66.42(n) 65.69(a)	424654 XM_422488.3 XP_422488.1
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.541²	Transcribed sequence with weak similarity to protein more	80.62(n)	142034388
zebrafish (Danio rerio)	Actinopterygii	zgc:158640¹	zgc:158640	58.08(n) 50.76(a)	790918 NM_001080065.1 NP_001073534.1

ENSEMBL Gene Tree for HSPB11 (if available)
TreeFam Gene Tree for HSPB11 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs138353645^1,2		--	54386918(+)	`CTCAGC/TGAAAC`	1	--	ds500¹		0	--	--	--	--
rs118033571^1,2	F,	--	54387010(+)	`ATCAAT/CTAAAA`	1	--	ds500¹		1		EA	120
rs191808583^1,2		--	54387029(+)	`CACTAC/TGATCT`	1	--	ds500¹		0	--	--	--	--
rs149637400^1,2	C,	--	54387288(+)	`AATATA/GTTGTT`	1	--	ut3¹		0	--	--	--	--
rs144341849^1,2	C,	--	54387327(+)	`CATTAC/TGAGGA`	2	S	syn¹		0	--	--	--	--
rs140103685^1,2	C,	--	54387395(+)	`AAAGGC/TTGATA`	2	T A	mis¹		0	--	--	--	--
rs184049812^1,2		--	54387425(+)	`AGTAGC/TGGAGC`	2	T A	mis¹		0	--	--	--	--
rs115436655^1,2	C,	--	54387445(+)	`CCTGTA/TTGGGA`	1	--	int¹		2		WA EU	1435
rs12090789^1,2	C,F,H,	--	54387577(+)	`TATAAT/CAGTTG`	1	--	int¹		20		NS EA NA WA CSA	2346
rs187518051^1,2		--	54387637(+)	`TGGAGC/GTAAAA`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for HSPB11 (54387234 - 54411975 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HSPB11: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPB11

DNA2.0 Custom Variant and Variant Library Synthesis for HSPB11

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for HSPB11 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with HSPB11)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2, 3} Zhang Q.-H.... Chen Z. (2000)
Characterization of mouse IFT complex B. (PubMed id 19253336)^{1, 3} Follit J.A....Pazour G.J. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Isolation and characterization of five new soluble placental tissue proteins (PP22, PP23, PP24, PP25, PP26). (PubMed id 2018407)^{1, 2} Bohn H. and Winckler W. (1991)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. (PubMed id 18816799)² Ramelot T.A.... Kennedy M.A. (2009)
Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors. (PubMed id 18154656)¹ Pozsgai E....Bellyei S. (2007)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51668	HGNC: 25019	AceView: C1orf41	Ensembl:ENSG00000081870	euGenes: HUgn51668
ECgene: HSPB11	H-InvDB: HSPB11

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for HSPB11	Pharmacogenomics, SNPs, Pathways

Intellectual Property for HSPB11 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for HSPB11 gene:
Search GeneIP for patents involving HSPB11

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPB11		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPB11
	OriGene Protein Over-expression Lysate for HSPB11		Browse OriGene Fluorogenic Cell Assay Kits
	Browse OriGene siRNAs		OriGene 3'-UTR Clone for HSPB11
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPB11
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for HSPB11		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for HSPB11		OriGene Custom Protein Services for HSPB11
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSPB11
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPB11
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPB11
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPB11
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPB11
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPB11

	GenScript Custom Purified and Recombinant Proteins Services for HSPB11		GenScript cDNA clones with any tag delivered in your preferred vector for HSPB11
	GenScript Custom Assay Services for HSPB11		GenScript Custom Superior Antibodies Services for HSPB11
	GenScript Custom overexpressing Cell Line Services for HSPB11		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in HSPB11 promoter
	Search Chromatin IP Primers for HSPB11
	RT² qPCR Primer Assay in human, mouse, rat HSPB11
	Search GNC Networks for HSPB11
	SABiosciences Custom PCR Arrays for HSPB11

Search Tocris compounds for HSPB11

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	HSPB11 antibodies
	HSPB11 proteins
	HSPB11 lysates

	Antibodies for HSPB11
	See all of Abcam's Antibodies, Kits and Proteins for HSPB11
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Recombinant Protein for HSPB11

Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn

Search LifeMap BioReagents cell lines for HSPB11

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for HSPB11

	Browse SwitchGear 3'UTR luciferase reporter plasmids for HSPB11
	SwitchGear Promoter luciferase reporter plasmids for HSPB11

ThermoFisher Antibody for HSPB11

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPB11

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes HSPB11 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

HSPB11 Gene

heat shock protein family B (small), member 11

Aliases
for HSPB11 gene

Summaries
for HSPB11 gene

Genomic Views
for HSPB11 gene

Proteins
for HSPB11 gene

Protein Domains /
Families
for HSPB11 gene

Function
for HSPB11 gene

Pathways & Interactions
for HSPB11 gene

Drugs & Compounds
for HSPB11 gene

Transcripts
for HSPB11 gene

Expression
for HSPB11 gene

Orthologs
for HSPB11 gene

Paralogs
for HSPB11 gene

Genomic Variants
for HSPB11 gene

Disorders / Diseases
for HSPB11 gene

Publications
for HSPB11 gene

External Searches for HSPB11 gene

Genome Databases showing HSPB11 gene

Other Databases showing HSPB11 gene

Specialized Databases showing HSPB11 gene

Intellectual Property
for HSPB11 gene

Products
for HSPB11 gene

View Random Gene

Advanced Search

Export list of displayed genes

HSPB11 Gene

heat shock protein family B (small), member 11

Aliasesfor HSPB11 gene

Summariesfor HSPB11 gene

Genomic Viewsfor HSPB11 gene

Proteinsfor HSPB11 gene

Protein Domains /Familiesfor HSPB11 gene

Functionfor HSPB11 gene

Pathways & Interactionsfor HSPB11 gene

Drugs & Compoundsfor HSPB11 gene

Transcriptsfor HSPB11 gene

Expression for HSPB11 gene

Orthologsfor HSPB11 gene

Paralogsfor HSPB11 gene

Genomic Variantsfor HSPB11 gene

Disorders / Diseasesfor HSPB11 gene

Publicationsfor HSPB11 gene

External Searches for HSPB11 gene

Genome Databases showing HSPB11 gene

Other Databases showing HSPB11 gene

Specialized Databases showing HSPB11 gene

Intellectual Propertyfor HSPB11 gene

Productsfor HSPB11 gene

View Random Gene

Aliases
for HSPB11 gene

Summaries
for HSPB11 gene

Genomic Views
for HSPB11 gene

Proteins
for HSPB11 gene

Protein Domains /
Families
for HSPB11 gene

Function
for HSPB11 gene

Pathways & Interactions
for HSPB11 gene

Drugs & Compounds
for HSPB11 gene

Transcripts
for HSPB11 gene

Expression
for HSPB11 gene

Orthologs
for HSPB11 gene

Paralogs
for HSPB11 gene

Genomic Variants
for HSPB11 gene

Disorders / Diseases
for HSPB11 gene

Publications
for HSPB11 gene

Intellectual Property
for HSPB11 gene

Products
for HSPB11 gene