Aliases for HSPB1 Gene
External Ids for HSPB1 Gene
Previous GeneCards Identifiers for HSPB1 Gene
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]
GeneCards Summary for HSPB1 Gene
HSPB1 (Heat Shock 27kDa Protein 1) is a Protein Coding gene. Diseases associated with HSPB1 include charcot-marie-tooth disease, axonal, type 2f and neuropathy, distal hereditary motor, type iib. Among its related pathways are MAPK signaling pathway and Akt Signaling. GO annotations related to this gene include identical protein binding and protein kinase C binding. An important paralog of this gene is CRYAA.
UniProtKB/Swiss-Prot for HSPB1 Gene
Involved in stress resistance and actin organization