Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HSPA7 Gene

pseudogene   GIFtS: 37
GCID: GC01P161575

Heat Shock 70kDa Protein 7 (HSP70B)

(Previous name: heat shock 70kD protein 7 (HSP70B))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Heat Shock 70kDa Protein 7 (HSP70B)1 2
HSP70B2 3
Heat Shock 70kD Protein 7 (HSP70B)1
Heat Shock 70 KDa Protein B3

External Ids:    HGNC: 52401   Entrez Gene: 33112   Ensembl: ENSG000002252177   OMIM: 1405565   UniProtKB: P487413   
ORGUL members:         
NONCODE14:n406626      

Export aliases for HSPA7 gene to outside databases

Previous GC identifers: GC01U990091 GC01P158763 GC01P158307 GC01P159842 GC01P159762 GC01P161494


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for HSPA7 Gene: 
HSPA7 (heat shock 70kDa protein 7 (HSP70B)) is a pseudogene, and is affiliated with the lncRNA class. Diseases associated with HSPA7 include choroiditis, and neuronitis, and among its related super-pathways are Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF). GO annotations related to this gene include ATP binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HSPA7 gene promoter:
         p53   AML1a   NRSF form 1   Hand1   STAT3   NRSF form 2   E47   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for HSPA7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.3

HSPA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPA7 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P161575:  view genomic region     (about GC identifiers)

Start:
161,575,849 bp from pter      End:
161,578,341 bp from pter
Size:
2,493 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HSP77_HUMAN, P48741 (See protein sequence)
Recommended Name: Putative heat shock 70 kDa protein 7  
Size: 367 amino acids; 40244 Da
Caution: Could be the product of a pseudogene
Secondary accessions: P19790

Explore the universe of human proteins at neXtProt for HSPA7: NX_P48741

Explore proteomics data for HSPA7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P48741

  • HSPA7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    HSPA7 Protein Expression

    Human Recombinant Protein Products for HSPA7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for HSPA7
    GenScript Custom Purified and Recombinant Proteins Services for HSPA7
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for HSPA7 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008180colocalizes with COP9 signalosome IDA18850735

    HSPA7 for ontologies           About GeneDecksing



    HSPA7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for HSPA7
    GenScript Custom Superior Antibodies Services for HSPA7
    Abcam antibodies for HSPA7
    Cloud-Clone Corp. Antibodies for HSPA7 
    Search ThermoFisher Antibodies for HSPA7
    LSBio Antibodies in human, mouse, rat for HSPA7 

    Assay Products for HSPA7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for HSPA7
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for HSPA7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for HSPA7 
    Cloud-Clone Corp. CLIAs for HSPA7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HSP70: Heat shock proteins / HSP70

    2 InterPro protein domains:
     IPR018181 Heat_shock_70_CS
     IPR013126 Hsp_70_fam

    Graphical View of Domain Structure for InterPro Entry P48741

    ProtoNet protein and cluster: P48741

    UniProtKB/Swiss-Prot: HSP77_HUMAN, P48741
    Similarity: Belongs to the heat shock protein 70 family


    HSPA7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for HSPA7:
    heat shock 70kDa protein A7,structurally related to aconitase

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding NAS--
         
    HSPA7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for HSPA7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HSPA7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HSPA7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HSPA7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPA7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HSPA7
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    Browse OriGene RNAi
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for HSPA7
    Sirion Biotech Customized adenovirus for overexpression of HSPA7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    Browse OriGene untagged/tagged cDNA clones in CMV expression vector
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for HSPA7
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPA7
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HSPA7
    Sirion Biotech Customized lentivirus for stable overexpression of HSPA7 
                         Customized lentivirus expression plasmids for stable overexpression of HSPA7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for HSPA7
    Search LifeMap BioReagents cell lines for HSPA7
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for HSPA7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway0.93
    Parkin-Ubiquitin Proteasomal System pathway0.89
    2CFTR folding and maturation (norm and CF)
    Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)0.37
    CFTR folding and maturation (norm and CF)0.37
    3Proteolysis Putative ubiquitin pathway
    Proteolysis Putative ubiquitin pathway0.97
    4Regulation of degradation of wt-CFTR
    Regulation of degradation of deltaF508 CFTR in CF0.59
    5Development Glucocorticoid receptor signaling
    Development Glucocorticoid receptor signaling1.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 EMD Millipore Pathways for HSPA7
        Development Glucocorticoid receptor signaling
    Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    Proteolysis Putative ubiquitin pathway


    5/6 GeneGo (Thomson Reuters) Pathways for HSPA7 (see all 6)
        Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
    Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    Regulation of degradation of deltaF508 CFTR in CF
    CFTR folding and maturation (norm and CF)
    Proteolysis Putative ubiquitin pathway

    1 BioSystems Pathway for HSPA7
        Parkin-Ubiquitin Proteasomal System pathway



    HSPA7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HSPA7

    5/8 Interacting proteins for HSPA7 (P487413) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARRB1P494073I2D: score=1 
    CFTRP135693I2D: score=1 
    COPS5Q929053I2D: score=1 
    GABARAPO951663I2D: score=1 
    GABARAPL1Q9H0R83I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006986response to unfolded protein NAS--

    HSPA7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HSPA7 (HSP77)

    Search CenterWatch for drugs/clinical trials and news about HSPA7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    Unigene Cluster for HSPA7:

    Heat shock 70kDa protein 7 (HSP70B)
    Hs.662180  [show with all ESTs]
    Unigene Representative Sequence: NR_024151
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000445535(uc010pkp.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPA7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate HSPA7
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    Browse OriGene RNAi
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA7
    Clone
    Products:
         
    Browse OriGene untagged/tagged cDNA clones in CMV expression vector
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for HSPA7
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPA7
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HSPA7
    Sirion Biotech Customized lentivirus for stable overexpression of HSPA7 
                         Customized lentivirus expression plasmids for stable overexpression of HSPA7 
    Primer
    Products:
        
    Browse OriGene qPCR
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat HSPA7
      Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA7

    Additional mRNA sequence: NR_024151.1 

    5 DOTS entries:

    DT.121462566  DT.453313  DT.100819773  DT.121462597  DT.100702473 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HSPA7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    HSPA7 Expression
    About this image


    See HSPA7 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.662180
        SABiosciences Custom PCR Arrays for HSPA7
    Primer
    Products:
    Browse OriGene qPCR
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat HSPA7
    Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for HSPA7 (if available)
    TreeFam Gene Tree for HSPA7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HSPA7 gene
    18 SIMAP similar genes for HSPA7 using alignment to 1 protein entry:     HSP77_HUMAN:
    HSPA6    HSPA1B    HSPA1A    HSP70-1    HSPA1L    HSPA2
    LOC401308    HSPA8    HSPA5    HSPA9    HS24/P52    HSPA14
    HS24/p52    HSPA4L    HSPA4    HYOU1    HSPA13    HSPH1

    HSPA7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 SNPs in HSPA7 are shown (see all 103)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1498634181,2
    C--168124693(+) ACGCCA/GGGGCA 1 -- us2k10--------
    rs1807083961,2
    --168124740(+) GTGAAA/GACCCA 1 -- us2k10--------
    rs1854903091,2
    --168124745(+) GACCCA/GTCTCT 1 -- us2k10--------
    rs1458592331,2
    --168124762(+) CCGTCA/GGCAAA 1 -- us2k10--------
    rs1899978521,2
    --168124789(+) TCCAGA/GTGTGA 1 -- us2k10--------
    rs1815921901,2
    --168124823(+) TGAATA/TTAAAG 1 -- us2k10--------
    rs1869078951,2
    --168124936(+) CATTCC/TCTTTT 1 -- us2k10--------
    rs1920573501,2
    --168124951(+) TGAACC/TGATCA 1 -- us2k10--------
    rs1489878401,2
    C--168124972(+) ACAGCC/TGATCT 1 -- us2k10--------
    rs1437476021,2
    C--168125016(+) GCTCTA/C/TGGAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for HSPA7 (161575849 - 161578341 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/42 variations for HSPA7 (see all 42):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv75e199CNV Deletion23128226
    esv2507888CNV Deletion19546169
    esv3325CNV Deletion18987735
    dgv50e201CNV Deletion23290073
    esv2718873CNV Deletion23290073
    dgv22n16CNV Deletion17901297
    nsv820341CNV Duplication20802225
    dgv24n16CNV Insertion17901297
    nsv509546CNV Insertion20534489
    dgv23n16CNV Insertion17901297

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing HSPA7
    DNA2.0 Custom Variant and Variant Library Synthesis for HSPA7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 140556    OMIM disorders: --

    2 diseases for HSPA7:    About MalaCards
    choroiditis    neuronitis


    HSPA7 for disorders           About GeneDecksing


    Export disorders for HSPA7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HSPA7 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with HSPA7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human Hsp70B gene at the HSPA7 locus of chromosome 1 is transcribed but non-functional. (PubMed id 11072087)1, 3, 9 Parsian A.J....Hunt C.R. (2000)
    2. The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. (PubMed id 1346391)1, 3 Leung T.K.C.... Lim L. (1992)
    3. Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment. (PubMed id 3927293)1, 2 Voellmy R.... Rungger D. (1985)
    4. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    5. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (2013)
    6. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. A proteomic investigation of ligand-dependent HSP90 c omplexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. (PubMed id 19875381)1 Gano J.J. and Simon J.A. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Charting the molecular network of the drug target Bcr-Abl. (PubMed id 19380743)1 Brehme M....Superti-Furga G. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3311 HGNC: 5240 Ensembl:ENSG00000225217 euGenes: HUgn3311 ECgene: HSPA7
    H-InvDB: HSPA7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HSPA7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for HSPA7 gene:
    Search GeneIP for patents involving HSPA7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   Browse OriGene RNAi products  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   Browse OriGene clones  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for HSPA7   OriGene Custom Protein Services for HSPA7  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSPA7
     QIAGEN SeqTarget long-range PCR primers for resequencing HSPA7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA7
     Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA7
     GenScript Custom Purified and Recombinant Proteins Services for HSPA7 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for HSPA7
     GenScript Custom Assay Services for HSPA7 GenScript Custom Superior Antibodies Services for HSPA7
     GenScript Custom overexpressing Cell Line Services for HSPA7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in HSPA7 promoter
     Search Chromatin IP Primers for HSPA7
     Search RT2 qPCR Primer Assays in human, mouse, rat HSPA7
     Search GNC Networks for HSPA7
     SABiosciences Custom PCR Arrays for HSPA7
     Search Tocris compounds for HSPA7 (HSP77)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Antibodies for HSPA7
     See all of Abcam's Antibodies, Kits and Proteins for HSPA7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for HSPA7
     Antibodies for HSPA7
     ELISAs for HSPA7
     CLIAs for HSPA7
     Search LifeMap BioReagents cell lines for HSPA7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA7
     Browse SwitchGear 3'UTR luciferase reporter plasmids for HSPA7
     Browse SwitchGear Promoter luciferase reporter plasmids for HSPA7
     Search ThermoFisher Antibodies for HSPA7
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HSPA7
     inGenious Targeting Laboratory - Custom generated mouse model solutions for HSPA7
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HSPA7
    Customized:
     lentivirus for stable overexpression of HSPA7
     lentivirus expression plasmids for stable overexpression of HSPA7
     adenovirus for overexpression of HSPA7
     LSBio Antibodies in human, mouse, rat for HSPA7
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      HSPA7 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4