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Aliases for HSPA7 Gene

Aliases for HSPA7 Gene

  • Heat Shock Protein Family A (Hsp70) Member 7 2 3 5
  • Heat Shock 70kDa Protein 7 (HSP70B) 2 3
  • Heat Shock 70kD Protein 7 (HSP70B) 2 3
  • HSP70B 3 4
  • Heat Shock 70 KDa Protein B 4

External Ids for HSPA7 Gene

Previous GeneCards Identifiers for HSPA7 Gene

  • GC01U990091
  • GC01P158763
  • GC01P158307
  • GC01P159842
  • GC01P159762
  • GC01P161494

Summaries for HSPA7 Gene

GeneCards Summary for HSPA7 Gene

HSPA7 (Heat Shock Protein Family A (Hsp70) Member 7) is a Pseudogene. Among its related pathways are Cellular response to heat stress and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF).

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSPA7 Gene

Genomics for HSPA7 Gene

Regulatory Elements for HSPA7 Gene

Enhancers for HSPA7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around HSPA7 on UCSC Golden Path with GeneCards custom track

Promoters for HSPA7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around HSPA7 on UCSC Golden Path with GeneCards custom track

Genomic Location for HSPA7 Gene

Chromosome:
1
Start:
161,606,059 bp from pter
End:
161,608,551 bp from pter
Size:
2,493 bases
Orientation:
Plus strand

Genomic View for HSPA7 Gene

Genes around HSPA7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSPA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSPA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSPA7 Gene

Proteins for HSPA7 Gene

  • Protein details for HSPA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P48741-HSP77_HUMAN
    Recommended name:
    Putative heat shock 70 kDa protein 7
    Protein Accession:
    P48741
    Secondary Accessions:
    • P19790

    Protein attributes for HSPA7 Gene

    Size:
    367 amino acids
    Molecular mass:
    40244 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSPA7 Gene

Proteomics data for HSPA7 Gene at MOPED

Post-translational modifications for HSPA7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for HSPA7 Gene

Domains & Families for HSPA7 Gene

Gene Families for HSPA7 Gene

Protein Domains for HSPA7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for HSPA7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P48741

UniProtKB/Swiss-Prot:

HSP77_HUMAN :
  • Belongs to the heat shock protein 70 family.
Family:
  • Belongs to the heat shock protein 70 family.
genes like me logo Genes that share domains with HSPA7: view

Function for HSPA7 Gene

Molecular function for HSPA7 Gene

GENATLAS Biochemistry:
heat shock 70kDa protein A7,structurally related to aconitase

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSPA7 Gene

Localization for HSPA7 Gene

Gene Ontology (GO) - Cellular Components for HSPA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with HSPA7: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for HSPA7 Gene

Pathways & Interactions for HSPA7 Gene

genes like me logo Genes that share pathways with HSPA7: view

Interacting Proteins for HSPA7 Gene

Selected Interacting proteins: P48741-HSP77_HUMAN for HSPA7 Gene via I2D

Gene Ontology (GO) - Biological Process for HSPA7 Gene

None

No data available for SIGNOR curated interactions for HSPA7 Gene

Drugs & Compounds for HSPA7 Gene

No Compound Related Data Available

Transcripts for HSPA7 Gene

mRNA/cDNA for HSPA7 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSPA7 Gene

Heat shock 70kDa protein 7 (HSP70B):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSPA7 Gene

No ASD Table

Relevant External Links for HSPA7 Gene

GeneLoc Exon Structure for
HSPA7
ECgene alternative splicing isoforms for
HSPA7

Expression for HSPA7 Gene

mRNA expression in normal human tissues for HSPA7 Gene

mRNA differential expression in normal tissues according to GTEx for HSPA7 Gene

This gene is overexpressed in Whole Blood (x5.9).

Protein differential expression in normal tissues from HIPED for HSPA7 Gene

This gene is overexpressed in Lavage (51.3) and Urine (16.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HSPA7 Gene



SOURCE GeneReport for Unigene cluster for HSPA7 Gene Hs.662180

genes like me logo Genes that share expression patterns with HSPA7: view

Protein tissue co-expression partners for HSPA7 Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for HSPA7 Gene

Orthologs for HSPA7 Gene

Evolution for HSPA7 Gene

ENSEMBL:
Gene Tree for HSPA7 (if available)
TreeFam:
Gene Tree for HSPA7 (if available)

No data available for Orthologs for HSPA7 Gene

Paralogs for HSPA7 Gene

(18) SIMAP similar genes for HSPA7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSPA7: view

No data available for Paralogs for HSPA7 Gene

Variants for HSPA7 Gene

Sequence variations from dbSNP and Humsavar for HSPA7 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs386730 -- 161,607,180(+) CTACA(A/C)GTCCA nc-transcript-variant
rs391125 -- 161,608,161(+) GTAGC(A/G)CTCAA nc-transcript-variant
rs391145 -- 161,606,938(+) GACGC(C/T)GGTGT nc-transcript-variant
rs393027 -- 161,607,117(+) CACCC(C/T)GTCCT nc-transcript-variant
rs394965 -- 161,608,171(+) AGCCC(A/C/G)CCAGG nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for HSPA7 Gene

Variant ID Type Subtype PubMed ID
dgv133e1 CNV Complex 17122850
dgv4n68 CNV Gain+Loss 17160897
dgv134e1 CNV Complex 17122850
nsv428257 CNV Loss 18775914
esv28122 CNV Gain+Loss 19812545
dgv8e55 CNV Gain 17911159
dgv135e1 CNV Complex 17122850
dgv136e1 CNV Complex 17122850
nsv8502 CNV Loss 18304495
esv33393 CNV Gain+Loss 17666407
nsv519779 CNV Loss 19592680
nsv464173 CNV Gain 19166990
nsv825176 CNV Gain 20364138
nsv820341 CNV Duplication 20802225
dgv398n71 CNV Gain 21882294
esv2718873 CNV Deletion 23290073
esv997087 CNV Loss 20482838
dgv22n16 CNV Deletion 17901297
dgv85n67 CNV Loss 20364138
nsv819523 CNV Loss 19587683
nsv818489 CNV Gain 17921354
nsv517640 CNV Gain+Loss 19592680
dgv137e1 CNV Complex 17122850
dgv138e1 CNV Complex 17122850
nsv872498 CNV Gain 21882294
essv6858 CNV CNV 17122850
dgv139e1 CNV Complex 17122850
nsv514915 CNV Complex 21397061
nsv818500 CNV Gain 17921354
nsv442209 CNV CNV 18776908
nsv509546 CNV Insertion 20534489
dgv23n16 CNV Insertion 17901297
esv2507888 CNV Deletion 19546169
esv990743 CNV Loss 20482838
nsv821621 CNV Loss 15273396
dgv50e201 CNV Deletion 23290073
dgv75e199 CNV Deletion 23128226
dgv24n16 CNV Insertion 17901297
nsv825242 CNV Loss 20364138
esv3325 CNV Deletion 18987735
esv5752 CNV Loss 19470904
nsv825254 CNV Gain 20364138

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for HSPA7 Gene

Disorders for HSPA7 Gene

Relevant External Links for HSPA7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSPA7

No disorders were found for HSPA7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSPA7 Gene

Publications for HSPA7 Gene

  1. The human Hsp70B gene at the HSPA7 locus of chromosome 1 is transcribed but non-functional. (PMID: 11072087) Parsian A.J. … Hunt C.R. (Biochim. Biophys. Acta 2000) 2 3 23 67
  2. The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. (PMID: 1346391) Leung T.K.C. … Lim L. (Genomics 1992) 2 3
  3. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. (PMID: 25756610) Papp S.J. … Lamia K.A. (Elife 2015) 3
  4. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3

Products for HSPA7 Gene

Sources for HSPA7 Gene

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