Aliases for HSPA6 Gene
External Ids for HSPA6 Gene
Previous GeneCards Identifiers for HSPA6 Gene
GeneCards Summary for HSPA6 Gene
HSPA6 (Heat Shock Protein Family A (Hsp70) Member 6) is a Protein Coding gene. Among its related pathways are Cellular Senescence and Development_Glucocorticoid receptor signaling. GO annotations related to this gene include enzyme binding and heat shock protein binding. An important paralog of this gene is HSPA1B.
UniProtKB/Swiss-Prot for HSPA6 Gene
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).