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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

HSPA6 Gene

protein-coding GIFtS: 66
GCID: GC01P161495

heat shock 70kDa protein 6 (HSP70B')

(Previous name: heat shock 70kD protein 6 (HSP70B') )

Explore 11 diseases affiliated with
HSPA6 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Heat Shock 70kDa Protein 6 (HSP70B')¹ ²
Heat Shock 70kD Protein 6 (HSP70B')¹ ²
Heat Shock 70 KDa Protein B'² ³
Heat Shock 70 KDa Protein 6²
HSP70B'³

External Ids:	HGNC: 5239¹	Entrez Gene: 3310²	Ensembl: ENSG00000173110⁷	OMIM: 140555⁵	UniProtKB: P17066³

Export aliases for HSPA6 gene to outside databases

Previous GC identifers: GC01P159211 GC01P157225 GC01P158271 GC01P158764 GC01P158765 GC01P158308 GC01P159760 GC01P132819

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: HSP76_HUMAN, P17066

Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate

the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate

in all these processes through their ability to recognize nonnative conformations of other proteins. They bind

extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane

translocation, or following stress-induced damage (By similarity)

Gene Wiki entry for HSPA6

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HSPA6 gene promoter:
p53 AML1a NRSF form 1 FOXD1 CUTL1 NRSF form 2 E47 STAT3 Hand1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HSPA6 promoter sequence

Search SABiosciences Chromatin IP Primers for HSPA6

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA6

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23 Ensembl cytogenetic band: 1q23.3 HGNC cytogenetic band: 1q23.3

HSPA6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPA6 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P161495: view genomic region (about GC identifiers)

Start:	161,494,036 bp from pter	End:	161,496,687 bp from pter
Size:	2,652 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HSP76_HUMAN, P17066 (See protein sequence)

Recommended Name: Heat shock 70 kDa protein 6

Size: 643 amino acids; 71028 Da

1 PDB 3D structure from and Proteopedia for HSPA6:

3FE1 (3D)

Secondary accessions: Q1HBA8 Q8IYK7 Q9BT95

Explore the universe of human proteins at neXtProt for HSPA6: NX_P17066

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P17066

HSPA6 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_002146.2

ENSEMBL proteins:

ENSP00000310219

Human Recombinant Protein Products:

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	Novus Biologicals HSPA6 Proteins Novus Biologicals HSPA6 Lysate
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for HSPA6
	Uscn Proteins for HSPA6

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008180	colocalizes with signalosome	IDA	18850735

HSPA6 for ontologies About GeneDecksing

HSPA6 Antibody Products:

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	ThermoFisher Antibody for HSPA6

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	Uscn ELISAs and CLIAs for HSPA6

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HSPA6 for domains About GeneDecksing

2 InterPro domains/families:

IPR018181 Heat_shock_70_CS

IPR013126 Hsp_70_fam

Graphical View of Domain Structure for InterPro Entry P17066

ProtoNet protein and cluster: P17066

1 Blocks protein family: IPB001023 Heat shock protein Hsp70

UniProtKB/Swiss-Prot: HSP76_HUMAN, P17066

Similarity: Belongs to the heat shock protein 70 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: HSP76_HUMAN, P17066

Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate

the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate

in all these processes through their ability to recognize nonnative conformations of other proteins. They bind

extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane

translocation, or following stress-induced damage (By similarity)

Induction: Only at higher temperatures, and no basal expression

Genatlas biochemistry entry for HSPA6:

heat shock 70kDa protein A6,structurally related to aconitase

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		hsa-miR-519d hsa-miR-20a hsa-miR-106a hsa-miR-106b hsa-miR-93 hsa-miR-20b hsa-miR-17 hsa-miR-526b*

		SwitchGear 3'UTR luciferase reporter plasmid: HSPA6 3' UTR sequence

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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for HSPA6

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HSPA6
		Search LifeMap BioReagents cell lines for HSPA6

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA6

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005524	ATP binding	IEA	--

HSPA6 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for HSPA6:

Decreased nuclei size in G2M

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)

	Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)	1.00			Development_Glucocorticoid receptor signaling	0.27
	CFTR folding and maturation (norm and CF)	0.37			Development Glucocorticoid receptor signaling	0.27

Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway

	Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway	1.00			Parkin-Ubiquitin Proteasomal System pathway	0.93
	Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway	0.93

Measles

Measles

1.00

Influenza A

0.35

Proteolysis Putative ubiquitin pathway

Proteolysis Putative ubiquitin pathway

1.00

Proteolysis_Putative ubiquitin pathway

0.97

Endocytosis

Endocytosis

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

3 EMD Millipore Pathways for HSPA6

	Development Glucocorticoid receptor signaling
	Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
	Proteolysis Putative ubiquitin pathway

5/6 GeneGo (Thomson Reuters) Pathways for HSPA6 (see all 6)

	Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
	Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
	Regulation of degradation of deltaF508 CFTR in CF
	CFTR folding and maturation (norm and CF)
	Proteolysis Putative ubiquitin pathway

1 BioSystems Pathway for HSPA6

Parkin-Ubiquitin Proteasomal System pathway

5/8 Kegg Pathways (Kegg details for HSPA6) (see all 8):

	Spliceosome
	MAPK signaling pathway
	Protein processing in endoplasmic reticulum
	Endocytosis
	Antigen processing and presentation

HSPA6 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for HSPA6

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/595 Interacting proteins for HSPA6 (P17066^{2, 3} ENSP00000310219⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 595)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COPS5	Q92905²^,³, ENSP00000350512⁴	MINT-7947479 I2D: score=1 STRING: ENSP00000350512
IKBKG	Q9Y6K9²^,³	MINT-48155 I2D: score=2
MAP3K1	Q13233²^,³	MINT-48290 I2D: score=2
MAP3K14	Q99558²^,³	MINT-48803 I2D: score=2
MAP3K3	Q99759²^,³	MINT-48405 I2D: score=2

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006986	response to unfolded protein	TAS	2327978

HSPA6 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

HSPA6 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HSPA6
2 Novoseek chemical compound relationships for HSPA6 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cdcl2	60	6	16155950 (5), 2327978 (1)
atp	22.7	6	16155950 (4), 15635096 (1), 2327978 (1)

Search CenterWatch for drugs/clinical trials and news about HSPA6 / HSP76

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HSPA6 gene:

NM_002155.3

Unigene Cluster for HSPA6:

Heat shock 70kDa protein 6 (HSP70B')

Hs.654614 [show with all ESTs]

Unigene Representative Sequence: NM_002155

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000309758(uc001gaq.3)

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		8 QIAGEN miScript miRNA Assays for microRNAs that regulate HSPA6:
		hsa-miR-519d hsa-miR-20a hsa-miR-106a hsa-miR-106b hsa-miR-93 hsa-miR-20b hsa-miR-17 hsa-miR-526b*

		SwitchGear 3'UTR luciferase reporter plasmid: HSPA6 3' UTR sequence

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		GenScript: all cDNA clones in your preferred vector: HSPA6 (NM_002155)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA6

Additional cDNA sequence:

AK093925.1 AK223362.1 AK295212.1 AK312756.1 BC004279.1 BC035665.1 X51758.1

6 DOTS entries:

DT.453313 DT.121462566 DT.100819773 DT.95346591 DT.100719416 DT.121462486

24/509 AceView cDNA sequences (see all 509):

AW451471 BX359383 CD368312 U87571 CR606721 BE349386 CD677831 R34695

BQ718336 D56797 U87566 U87565 AI523174 U87567 AL540745 AA370839

BQ023141 T29511 NM_001002274 CR611092 BC019931 BX335112 CR593693 AI057418

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HSPA6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGAATTTT

About this image

HSPA6 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Right Ventricle

Heart

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See HSPA6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSPA6

SOURCE GeneReport for Unigene cluster: Hs.654614

SABiosciences Expression via Pathway-Focused PCR Array including HSPA6:

Heat Shock Proteins & Chaperones in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for HSPA6 gene from 3/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
zebrafish (Danio rerio)	Actinopterygii	hsp70l⁶ hsp70.3⁶ (see all 5)	heat shock cognate 70-kd protein, like heat shock cognate 70-kd protein, tandem duplicate... (see all 5)	79(a) 79(a) (see all 5)	many ↔ many many ↔ many (see all 5)	8(5006699-5009452) 3(26908016-26911371)
fruit fly (Drosophila melanogaster)	Insecta	Hsc70-4³	neurotransmitter secretion chaperone	79(a) (best of 11)		88E4 --
worm (Caenorhabditis elegans)	Secernentea	hsp-1³	HSP-1 heat shock 70kd protein A	80(a) (best of 7)		IV(17279119-17281340) --

ENSEMBL Gene Tree for HSPA6 (if available)
TreeFam Gene Tree for HSPA6 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for HSPA6 gene

HSPA8² HSPA5² HSPA1L² HSPA1B² HSPA14² HSPA13² HSPA1A²

16 SIMAP similar genes for HSPA6 using alignment to 1 protein entry: HSP76_HUMAN:

HSPA7 HSP70-1 HSPA2 HSPA1B HSPA8 LOC401308

HSPA1L HSPA1A HSPA5 HSPA9 HSPA14 HS24/p52

HSPA13 HSPA4 HSPA4L HSPH1

HSPA6 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for HSPA6
PGOHUM00000245047 PGOHUM00000237551

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs78878274^1,2	C	--	132817464(-)	`TGTCAA/GCTTTA`	1	--	us2k¹		0	--	--	--	--
rs76600300^1,2	C	--	132818321(+)	`CCATAG/AAGAAA`	1	--	us2k¹		2		NA	6
rs3754052^1,2	C,A,H	--	132819611(-)	`CGCTCC/GGTGTC`	2	T	syn¹ ese³		2		NA WA	6
rs400835^1,2	C,F,A,H,	--	132819748(+)	`CTTCCG/AGGTGG`	3	/P /R /L	mis¹ ese³		9		EA NA MN NS	420
rs1079109^1,2	C,F,H	--	132820056(+)	`ACGTGC/TTCATT`	3	I L V	mis¹		11		NA MN NS	514
rs41297718^1,2	F	--	132820354(+)	`CTACAC/AGTCCA`	3	/T /R /M	mis¹		5		NS	176
rs17853454^1,2	C,F,	--	132820493(+)	`TCCACT/ACGCAT`	2	/T	syn¹ ese³		10		NS NA WA CSA	200
rs9659608^1,2	C,A	--	132820587(+)	`ATGGGG/TCTGCT`	3	T P A	mis¹ ese³		0	--	--	--	--
rs450363^1,2	F,A,	--	132820804(+)	`TGAGGG/TTGAGA`	3	D A G	mis¹		1		MN	184
rs79983347^1,2	F	--	132821046(+)	`AGTACA/GGGGCT`	3	K Q *	mis¹ stg¹		2		NA	6

HapMap Linkage Disequilibrium report for HSPA6 (161494036 - 161496687 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 12 variations for HSPA6
12 CNVs: 6791 22935 9375 3316 58342 2329 65090 4258 8335 31666 65089 22934

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA6

DNA2.0 Custom Variant and Variant Library Synthesis for HSPA6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HSPA6 for disorders           About GeneDecksing

OMIM gene information: 140555    OMIM disorders: --

11 diseases for HSPA6:    About MalaCards

chronic lymphocytic leukemia lymphocytic leukemia toxoplasmosis vascular disease

measles meningioma influenza leukemia

breast cancer immunodeficiency neuronitis

1 Novoseek disease relationship for HSPA6 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
shock	55.3	4	20348092 (1), 16782652 (1), 16155950 (1), 8940068 (1)

Human Genome Epidemiology (HuGE) Navigator: HSPA6 (12 documents)

Export disorders for HSPA6 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for HSPA6 gene, integrated from 9 sources (see all 68):
(articles sorted by number of sources associating them with HSPA6)

Utopia: connect your pdf to the dynamic
world of online information

The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. (PubMed id 1346391)^{1, 2, 3} Leung T.K.C.... Lim L. (1992)
The human heat-shock protein family. Expression of a novel heat- inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. (PubMed id 2327978)^{1, 2, 9} Leung T.K.C.... Lim L. (1990)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Cis-acting elements involved in the regulated expression of a human HSP70 gene. (PubMed id 3184191)^{1, 2} Schiller P.... Voellmy R. (1988)
Heat shock protein 70B' (HSP70B') expression and rele ase in response to human oxidized low density lipoprotein immune complexes in m acrophages. (PubMed id 20348092)^{1, 9} Smith K.J....Hammad S.M. (2010)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
Global landscape of HIV-human protein complexes. (PubMed id 22190034)¹ Jager S....Krogan N.J. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Shotgun proteomics and network analysis of ubiquitin-r elated proteins from human breast carcinoma epithelial cells. (PubMed id 21853274)¹ Zhou J....Liang S. (2012)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 3310	HGNC: 5239	AceView: HSPA6andFCGR2A	Ensembl:ENSG00000173110	euGenes: HUgn3310
ECgene: HSPA6	Kegg: 3310	H-InvDB: HSPA6

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for HSPA6	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for HSPA6	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/hspa6/

Intellectual Property for HSPA6 gene
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Patent Information for HSPA6 gene:
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heat shock 70kDa protein 6 (HSP70B')

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heat shock 70kDa protein 6 (HSP70B')

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