HSPA4 Gene
protein-coding GIFtS: 63
GCID: GC05P132415
|
|
heat shock 70kDa protein 4(Previous name: heat shock 70kD protein 4 )
| |
Aliases
for HSPA4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Heat Shock 70kDa Protein 41 2 | | Heat Shock 70 KDa Protein 42 | | HS24/P521 2 | | Heat Shock Protein, 110 KDa2 | | HSPH21 2 | | Hsp701 | | Heat Shock 70kD Protein 41 2 | | Hsp70 RY2 | | Heat Shock 70-Related Protein APG-22 3 | | Hsp70RY1 | | APG-22 | | APG23 | | RY2 | | HSP70RY3 |
Export aliases for HSPA4 gene to outside databasesPrevious GC identifers: GC05P131909 GC05P132834 GC05P132418 GC05P132463 GC05P127579 |
Summaries
for HSPA4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for HSPA4
|
Genomic Views
for HSPA4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HSPA4 gene promoter:
CREB AP-1 ATF-2 deltaCREB c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for HSPA4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1HSPA4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P132415: view genomic region
(about GC identifiers)
Start:
|
132,387,654 bp from pter |
End:
|
132,442,141 bp from pter |
Size:
|
54,488 bases |
Orientation:
|
plus strand |
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Proteins
for HSPA4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HSP74_HUMAN, P34932 (See
protein sequence)Recommended Name: Heat shock 70 kDa protein 4 Size: 840 amino acids; 94331 Da
Subunit: Interacts with TJP1/ZO-1 (By similarity)
Subcellular location: Cytoplasm (Probable)
Sequence caution: Sequence=AAA02807.1; Type=Frameshift; Positions=567, 586, 697, 715, 722;
Secondary accessions: O95756 Q2TAL4Explore the universe of human proteins at neXtProt for HSPA4: NX_P34932
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P34932
HSPA4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002145.3
ENSEMBL proteins: ENSP00000302961
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
HSPA4 for ontologies About GeneDecksing
HSPA4 Antibody Products:
Assay Products for HSPA4: |
Protein
Domains /
Families
for HSPA4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HSPA4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P34932ProtoNet protein and cluster: P34932 UniProtKB/Swiss-Prot: HSP74_HUMAN, P34932Similarity: Belongs to the heat shock protein 70 family |
Function
for HSPA4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for HSPA4:heat shock 70kDa protein A4,structurally related to aconitase
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HSPA4 (NM_002154) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSPA4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA4 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
HSPA4 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Hspa4tm1Imad for HSPA4
6 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Hspa4):
HSPA4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for HSPA4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) | | | 2 | Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway | | | 3 | Proteolysis Putative ubiquitin pathway | | | 4 | Glucocorticoid Pathway (Peripheral Tissue), Pharmacodynamics | | | 5 | Androgen Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for HSPA4
1  R&D Systems Pathway for HSPA4
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HSPA4
5/6  GeneGo (Thomson Reuters) Pathways for HSPA4 (see all 6)
2  BioSystems Pathways for HSPA4
1  PharmGKB Pathway for HSPA4
1 
Kegg Pathway (Kegg details for HSPA4):
HSPA4 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for HSPA4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/252 Interacting proteins for HSPA4 (P349322, 3 ENSP000003029614) via UniProtKB, MINT, STRING, and/or I2D (see all 252)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
HSPA4 for ontologies About GeneDecksing
|
Drugs & Compounds
for HSPA4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HSPA4 for compounds About GeneDecksing
 Browse Tocris compounds for HSPA4
10/149 Novoseek chemical compound relationships for HSPA4 gene (see all 149) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| geldanamycin |
76.9 |
44 |
19995547 (5), 16311509 (3), 18852129 (3), 14633716 (2) (see all 18) |
| 17-(allylamino)-17-demethoxygeldanamycin |
75.7 |
20 |
19383903 (4), 20090934 (2), 18429957 (2), 11280726 (1) (see all 11) |
| pga1 |
71.4 |
31 |
8548766 (5), 7769835 (5), 8468116 (2), 11037055 (2) (see all 10) |
| sodium arsenite |
67.1 |
27 |
19358893 (4), 11740261 (3), 11322385 (3), 8464927 (1) (see all 16) |
| geranylgeranylacetone |
64.4 |
43 |
17182004 (7), 11693530 (5), 17702888 (4), 17684364 (3) (see all 10) |
| ggmp |
63.7 |
2 |
9447991 (1), 8887650 (1) |
| quercetin |
56.7 |
94 |
8198534 (8), 12969528 (4), 19017364 (4), 14625852 (4) (see all 37) |
| cdcl2 |
54.2 |
15 |
9545559 (4), 8375467 (2), 15764298 (2), 9344607 (1) (see all 10) |
| pga2 |
54.2 |
15 |
9824682 (4), 20153327 (2), 1549109 (2), 7926370 (1) |
| atp |
53.2 |
109 |
12832480 (3), 9830049 (3), 2203539 (2), 11170435 (2) (see all 74) |
Search CenterWatch for drugs/clinical trials and news about HSPA4 / HSP74
|
Transcripts
for HSPA4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HSPA4 gene (2 alternative transcripts): NM_198431.1 NM_002154.3 Unigene Cluster for HSPA4: Heat shock 70kDa protein 4 Hs.90093 [show with all ESTs]Unigene Representative Sequence: NM_0021543 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000304858(uc003kyj.3) ENST00000504328 ENST00000514825
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HSPA4 (NM_002154) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSPA4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA4 |
Additional cDNA sequence: AB023420.1 AB074275.1 AB209151.1 AK294859.1 AK295847.1 AK297762.1 AK299710.1 AK300050.1 AK300770.1 AK303382.1 AK304578.1 AK311097.1 AK311125.1 AK311135.1 AK311224.1 AK311299.1 AK311316.1 AK311422.1 AK311457.1 AK311465.1 AK311466.1 AK311471.1 AK311483.1 AK311615.1 AK311632.1 AK315862.1 AK315871.1 AK315875.1 AK315887.1 BC002526.2 BC110861.1 BC126122.1 BC126124.1 BT007375.1 L12723.1 X67643.1 18 DOTS entries: DT.100821700 DT.445307 DT.100821697 DT.40105813 DT.95169241 DT.217041 DT.95169252 DT.100821693 DT.100821695 DT.91828289 DT.99929734 DT.100030800 DT.95169249 DT.120883687 DT.120883716 DT.95088201 DT.95169244 DT.70100908 24/401 AceView cDNA sequences (see all 401): BC002526 CK905042 AI005006 AA665471 BU685927 BU171424 CN481241 AU138494 BE857936 AI799801 BE388253 BU542656 NM_002154 AI742972 BE388732 AI911599 BF026277 AA948300 BM787246 BM746586 AA433916 AA442855 BX482095 AA370218
GeneLoc Exon Structure
|
Expression
for HSPA4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HSPA4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATCCAGTTG
About this image
See HSPA4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSPA4
SOURCE GeneReport for Unigene cluster: Hs.90093
SABiosciences Expression via Pathway-Focused PCR Arrays including HSPA4 (see all 9):
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HSPA4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA4 |
Orthologs
for HSPA4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for HSPA4 gene from 10/37 species (see all 37) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
HSPA41 |
heat shock 70kDa protein 4 |
79.71(n)
85.92(a) |
|
416339 XM_003642094.1 XP_003642142.1 |
lizard
(Anolis carolinensis) |
Reptilia |
HSPA46 |
-- |
85(a) |
1 ↔ 1 |
2(127095467-127135197) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.57992 |
Xenopus laevis, Similar to heat shock 70 kDa protein more |
79.73(n) |
|
BC041515.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc41d052 |
Danio rerio cDNA clone MGC55506 IMAGE2641035, complete more |
76.26(n) |
|
BC051152.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Hsc70Cb6 |
Hsc70Cb |
43(a) |
1 → many |
3L(14030119-14036786) |
worm
(Caenorhabditis elegans) |
Secernentea |
C30C11.43 |
Msi3p |
42(a) |
|
III(8515890-8517059) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
SSE11 |
Sse1p |
49.53(n)
41.46(a) |
|
855998 NP_015219.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
HSP911 |
heat shock protein 91 |
50.97(n)
41.61(a) |
|
844333 NM_106642.4 NP_178111.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.264952 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
69.88(n) |
|
AK122040.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
hscC6 |
Hsp70 family chaperone Hsc62, binds to RpoD and in... |
20(a) |
1 → many |
Chromosome(680946-682616) |
ENSEMBL Gene Tree for HSPA4 (if available)
TreeFam Gene Tree for HSPA4 (if available) |
Paralogs
for HSPA4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HSPA4 gene
- HYOU12 HSPA4L2 HSPH12
15 SIMAP similar genes for HSPA4 using alignment to 2 protein entries: HSP74_HUMAN (see all proteins):HS24/P52 HS24/p52 HSPA4L HSPH1 HSP70-1 HSPA7
HSPA1A HSPA1L HSPA14 HSPA1B HSPA6 HSPA8
HSPA2 HSPA5 HYOU1
HSPA4 for paralogs About GeneDecksing
|
Genomic Variants
for HSPA4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HSPA4 (132387654 - 132442141 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HSPA4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA4 |
|
Disorders
/ Diseases
for HSPA4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HSPA4 for disorders About GeneDecksing
OMIM gene information: 601113
OMIM disorders: --
20/180  diseases for HSPA4 (see all 180): About MalaCardsspinocerebellar ataxia type 7 inner ear disease autoimmune inner ear disease human t-cell leukemia virus type 1
hypersensitivity reaction type ii disease lichen planus transient cerebral ischemia graft versus host disease
non-small cell lung carcinoma arterial occlusive disease peripheral arterial occlusive disease spinocerebellar ataxia
oral lichen planus pre-eclampsia bacterial vaginosis squamous cell carcinoma
cervical intraepithelial neoplasia multiple endocrine neoplasia coronary heart disease menieres disease
5 diseases from the University of Copenhagen DISEASES database for HSPA4:Vascular disease Cancer Neurodegenerative disease Brain disease
Toxic encephalopathy 10/91 Novoseek disease relationships for HSPA4 gene (see all 91) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| shock |
95.2 |
1759 |
12969528 (9), 1910812 (5), 18088459 (5), 19670094 (4) (see all 99) |
| tumors |
47.9 |
385 |
16224158 (5), 19309230 (5), 16769335 (5), 9585177 (4) (see all 99) |
| ischemia |
40.7 |
139 |
8249024 (7), 8364736 (6), 8239864 (6), 7982052 (4) (see all 47) |
| cancer |
40 |
122 |
19716411 (4), 15553822 (4), 15741319 (4), 19017364 (3) (see all 69) |
| cell damage |
35.6 |
15 |
20123033 (2), 16492383 (2), 17209876 (1), 7922267 (1) (see all 10) |
| spinocerebellar ataxia type 7 |
34.7 |
1 |
16039988 (1) |
| neurodegenerative diseases |
34.6 |
5 |
15673657 (1), 10562718 (1), 17536171 (1), 11044589 (1) (see all 5) |
| necrosis |
34.1 |
54 |
11341981 (3), 9755110 (2), 18336662 (2), 7749813 (2) (see all 40) |
| muscular dystrophy oculopharyngeal |
33.5 |
1 |
14729833 (1) |
| erythroleukemia |
30.4 |
8 |
9738016 (2), 17213196 (1), 9389084 (1), 16706166 (1) (see all 7) |
Genetic Association Database (GAD): HSPA4
Human Genome Epidemiology (HuGE) Navigator: HSPA4 (8 documents)
Export disorders for HSPA4 gene to outside databases
|
Publications
for HSPA4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HSPA4 gene, integrated from 9 sources (see all 1824):
(articles sorted by number of sources associating them with HSPA4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5. (PubMed id 8335910)1, 2, 3 Fathallah D.M.... Arnaout M.A. (1993)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- 1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients. (PubMed id 15992611)1, 4 Giacconi R....Mocchegiani E. (2005)
- Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes. (PubMed id 15507967)1, 4 Kalish R.B....Witkin S.S. (2004)
- Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes. (PubMed id 10524232)1, 9 Nonoguchi K.... Fujita J. (1999)
- Identification of residues on Hsp70 and Hsp90 ubiquit inated by the cochaperone CHIP. (PubMed id 19913553)1, 9 Kundrat L. and Regan L. (2010)
- A dual role for HSP90 and HSP70 in the inflammatory m yopathies: from muscle fiber protection to active invasion by macrophages. (PubMed id 19758187)1, 9 De Paepe B....De Bleecker J.L. (2009)
- [Expression characteristics of heat shock protein 70 and pim-1 gene in bone marrow mononuclear cells from leukemia patients and their clinical significance] (PubMed id 18426646)1, 9 Li Y....Peng H.L. (2008)
- Hsp70 interacts with the retroviral restriction facto r TRIM5alpha and assists the folding of TRIM5alpha. (PubMed id 20053985)1, 9 Hwang C.Y....Song B. (2010)
- Helicobacter pylori inhibits expression of heat shock protein 70 (HSP70) in human epithelial cell line. Importance of Cag A protein. (PubMed id 16845230)1, 9 Targosz A....Pawlik W.W. (2006)
|
External Searches for HSPA4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HSPA4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing HSPA4 gene
(According to HUGE)
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Specialized Databases showing HSPA4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for HSPA4 gene:
Search GeneIP for patents involving HSPA4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for HSPA4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPA4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA4 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HSPA4 | | OriGene 3'-UTR Clone for HSPA4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HSPA4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HSPA4 | | OriGene Custom Protein Services for HSPA4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSPA4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA4 |
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| | | | Search Tocris compounds for HSPA4 |
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 | | | HSPA4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA4 |
|  |  |  | | | | ThermoFisher Antibody for HSPA4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA4 |
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