HSPA14 Gene
protein-coding GIFtS: 55
GCID: GC10P014790
|
|
heat shock 70kDa protein 14
| |
Aliases
for HSPA14 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Heat Shock 70kDa Protein 141 2 | | HSP70-Like Protein 12 3 | | HSP70L11 2 3 5 | | Heat Shock 70 KDa Protein 142 | | HSP70-41 2 | | Heat Shock Protein Hsp70-Related Protein2 | | Heat Shock Protein HSP602 3 | | HSP603 |
Export aliases for HSPA14 gene to outside databasesPrevious GC identifers: GC10P014885 GC10P014920 |
Summaries
for HSPA14 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: HSP7E_HUMAN, Q0VDF9Function: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascentpolypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2stimulates its ATPase activity
Gene Wiki entry for HSPA14
|
Genomic Views
for HSPA14 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HSPA14 gene promoter:
p53 ATF-2 HSF1 (long) POU6F1 (c2) MEF-2A CRE-BP1 PPAR-gamma1 HSF1short PPAR-gamma2 aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for HSPA14
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA14 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p13 Ensembl cytogenetic band: 10p13 HGNC cytogenetic band: 10p13HSPA14 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P014790: view genomic region
(about GC identifiers)
Start:
|
14,880,163 bp from pter |
End:
|
14,913,740 bp from pter |
Size:
|
33,578 bases |
Orientation:
|
plus strand |
|
Proteins
for HSPA14 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HSP7E_HUMAN, Q0VDF9 (See
protein sequence)Recommended Name: Heat shock 70 kDa protein 14 Size: 509 amino acids; 54794 Da
Subunit: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 andHsp40/DnaJ-type chaperone DNAJC2
Subcellular location: Cytoplasm, cytosol
Miscellaneous: Acts as a potent immunoadjuvant, capable to interact with antigen-presenting cells and generatingefficient CD8(+) T-cell responses. May be used as adjuvant to enhance effect of vaccine G1F/M2, a candidate vaccineagainst respiratory syncytial virus (RSV), a major respiratory pathogen in newborns (PubMed:18851947). May also beused as adjuvant to prepare antigenic fusion protein for the therapeutics of cancers (PubMed:15930317)
Secondary accessions: A8K8F8 B0YIY9 Q9P0X2 Q9UI07Explore the universe of human proteins at neXtProt for HSPA14: NX_Q0VDF9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q0VDF9
HSPA14 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057383.2
ENSEMBL proteins: ENSP00000367623 ENSP00000390513 ENSP00000404691 ENSP00000309384
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
HSPA14 for ontologies About GeneDecksing
HSPA14 Antibody Products:
Assay Products for HSPA14: |
Protein
Domains /
Families
for HSPA14 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HSPA14 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q0VDF9ProtoNet protein and cluster: Q0VDF9 1 Blocks protein family: IPB001023 Heat shock protein Hsp70
UniProtKB/Swiss-Prot: HSP7E_HUMAN, Q0VDF9Similarity: Belongs to the heat shock protein 70 family |
Function
for HSPA14 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: HSP7E_HUMAN, Q0VDF9Function: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascentpolypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2stimulates its ATPase activity
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: HSPA14 (NM_016299) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSPA14 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA14 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA14 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
HSPA14 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for HSPA14:
|
Pathways & Interactions
for HSPA14 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) | | | 2 | Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway | | | 3 | Proteolysis Putative ubiquitin pathway | | | 4 | Regulation of degradation of wt-CFTR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for HSPA14
5/6  GeneGo (Thomson Reuters) Pathways for HSPA14 (see all 6)
1  BioSystems Pathway for HSPA14
HSPA14 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HSPA14
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for HSPA14 (Q0VDF93 ENSP000003676234) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
HSPA14 for ontologies About GeneDecksing
|
Drugs & Compounds
for HSPA14 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HSPA14 for compounds About GeneDecksing
 Browse Tocris compounds for HSPA14
10 Novoseek chemical compound relationships for HSPA14 gene About this table
Search CenterWatch for drugs/clinical trials and news about HSPA14 / HSP7E
|
Transcripts
for HSPA14 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HSPA14 gene: NM_016299.2 Unigene Clusters for HSPA14: Heat shock 70kDa protein 14 Hs.534169 [show with all ESTs], Hs.736996 Unigene Representative Sequences: AK226065, BC01569610 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000378372(uc010qbw.2 uc001inf.3) ENST00000493863 ENST00000437161(uc001ine.3)
ENST00000494337(uc001ind.3) ENST00000493178 ENST00000481379 ENST00000441647
ENST00000493614 ENST00000470430 ENST00000309584
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: HSPA14 (NM_016299) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSPA14 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA14 |
Additional cDNA sequence: BC015696.2 9 DOTS entries: DT.101326 DT.445741 DT.40112535 DT.91853987 DT.86840710 DT.101968507 DT.40131920 DT.40215847 DT.430691 24/248 AceView cDNA sequences (see all 248): BQ023510 AA417742 AW408674 BM765434 CA448435 AK000880 AI880192 AW016387 AI675179 AL138383 BQ954088 CR590065 BQ940185 BC026226 BQ008496 BC065281 BX471742 BC015696 AA910817 BI260382 AA715110 N48644 BU751964 CR601479
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for HSPA14 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for HSPA14
|
Expression
for HSPA14 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HSPA14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACAGATCAA
About this image
See HSPA14 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSPA14
SOURCE GeneReport for Unigene clusters: Hs.534169 Hs.736996
SABiosciences Expression via Pathway-Focused PCR Array including HSPA14:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA14
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HSPA14 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA14 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA14 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA14 |
Orthologs
for HSPA14 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for HSPA14 gene from 9/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
HSPA141 |
heat shock 70kDa protein 14 |
77.58(n)
83.13(a) |
|
418802 XM_416996.3 XP_416996.3 |
lizard
(Anolis carolinensis) |
Reptilia |
HSPA146 |
-- |
80(a) |
1 ↔ 1 |
GL343559.1(231542-246464) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.121972 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.5(n) |
|
BX854226.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
hspa141 |
heat shock protein 14 |
67.33(n)
71.2(a) |
|
565232 NM_001045076.1 NP_001038541.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG71826 |
-- |
24(a) |
1 ↔ 1 |
3L(8337521-8339306) |
worm
(Caenorhabditis elegans) |
Secernentea |
F11F1.16 |
Protein F11F1.1, isoform c |
21(a) |
possible ortholog |
III(13395605-13400505) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
HSP70T-26 |
heat-shock protein 70T-2 |
14(a) |
possible ortholog |
2(13651510-13653921) |
rice
(Oryza sativa) |
Liliopsida |
---- |
DnaK family protein, putative, expressedretrotransposon protein, putative, Ty1-copia subcl... |
15(a)11(a) |
possible orthologpossible ortholog |
3(6242990-6246317) 4(7473315-7478312) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
hscC6 |
Hsp70 family chaperone Hsc62, binds to RpoD and in... |
21(a) |
1 → many |
Chromosome(680946-682616) |
ENSEMBL Gene Tree for HSPA14 (if available)
TreeFam Gene Tree for HSPA14 (if available) |
Paralogs
for HSPA14 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HSPA14 gene
- HSPA82 HSPA52 HSPA1L2 HSPA1B2 HSPA62 HSPA132 HSPA1A2
14 SIMAP similar genes for HSPA14 using alignment to 7 protein entries: HSP7E_HUMAN (see all proteins):HSPA8 HSPA1L HSPA9 HSPA1A HSPA2 HSPA5
HSPA6 HSPA7 HSPA1B HSPA4 HS24/p52 HSPA4L
HSPH1 HYOU1
HSPA14 for paralogs About GeneDecksing
|
Genomic Variants
for HSPA14 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HSPA14 (14880163 - 14913740 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HSPA14: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA14 |
|
Disorders
/ Diseases
for HSPA14 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HSPA14 for disorders About GeneDecksing
OMIM gene information: 610369
OMIM disorders: --
20/30  diseases for HSPA14 (see all 30): About MalaCardssudden infant death syndrome non-small cell lung carcinoma plasmodium falciparum malaria tetralogy of fallot
rheumatoid arthritis endometrial carcinoma cryptorchidism anoxia
multiple myeloma paralysis lung carcinoma arthritis
breast cancer ischemia fibrosarcoma myeloma
alzheimer's disease laryngitis colon cancer gastric cancer
9 Novoseek disease relationships for HSPA14 gene About this table
Human Genome Epidemiology (HuGE) Navigator: HSPA14 (5 documents)
Export disorders for HSPA14 gene to outside databases
|
Publications
for HSPA14 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HSPA14 gene, integrated from 9 sources (see all 144):
(articles sorted by number of sources associating them with HSPA14) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. (PubMed id 16002468)1, 2 Otto H....Rospert S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant. (PubMed id 14592822)1, 2 Wan T.... Cao X. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity. (PubMed id 21208456)1 Wu C.Y....Wu K.J. (2011)
- Toll-like receptor 4 (TLR4) is essential for Hsp70-li ke protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response. (PubMed id 21730052)1 Fang H....Wan T. (2011)
|
External Searches for HSPA14 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HSPA14 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HSPA14 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HSPA14 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HSPA14 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HSPA14 gene:
Search GeneIP for patents involving HSPA14
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HSPA14 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for HSPA14 | | OriGene shRNA RFP for HSPA14 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPA14 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA14 | | | OriGene Protein Over-expression Lysate for HSPA14 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HSPA14 | | OriGene 3'-UTR Clone for HSPA14 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA14 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for HSPA14 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HSPA14 | | OriGene Custom Protein Services for HSPA14 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSPA14 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA14 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA14 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA14 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA14 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA14 |
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| | | | Search Tocris compounds for HSPA14 |
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 | | | HSPA14 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA14 |
|  |  |  | | | | ThermoFisher Antibodies for HSPA14 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA14 |
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