Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

HSPA12A Gene

protein-coding GIFtS: 50
GCID: GC10M118420

heat shock 70kDa protein 12A

(Previous name: heat shock 70kD protein 12A )

Explore 1 disease affiliated with
HSPA12A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Heat Shock 70kDa Protein 12A¹ ²
KIAA0417¹ ³ ⁵
Heat Shock 70kD Protein 12A¹ ²
FLJ13874¹
Heat Shock 70 KDa Protein 12A²

External Ids:	HGNC: 19022¹	Entrez Gene: 259217²	Ensembl: ENSG00000165868⁷	OMIM: 610701⁵	UniProtKB: O43301³

Export aliases for HSPA12A gene to outside databases

Previous GC identifers: GC00U991243 GC10U900081 GC10M118095 GC10M112058

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HSPA12A gene promoter:
LHX3b/Lhx3b SREBP-1c Olf-1 E47 SREBP-1b C/EBPalpha CHOP-10 SREBP-1a LHX3a/Lhx3a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for HSPA12A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA12A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.12 Ensembl cytogenetic band: 10q25.3 HGNC cytogenetic band: 10q25.3

HSPA12A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSPA12A gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M118420: view genomic region (about GC identifiers)

Start:	118,430,703 bp from pter	End:	118,502,085 bp from pter
Size:	71,383 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: HS12A_HUMAN, O43301 (See protein sequence)

Recommended Name: Heat shock 70 kDa protein 12A

Size: 675 amino acids; 74978 Da

Sequence caution: Sequence=BAA24847.1; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for HSPA12A: NX_O43301

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O43301

HSPA12A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_079291.2

ENSEMBL proteins:

ENSP00000358211 ENSP00000466041 ENSP00000466927

Human Recombinant Protein Products for HSPA12A:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: HSPA12A OriGene Custom Protein Services for HSPA12A
	GenScript Custom Purified and Recombinant Proteins Services for HSPA12A
	Novus Biologicals HSPA12A Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for HSPA12A

HSPA12A Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for HSPA12A
	GenScript Custom Superior Antibodies Services for HSPA12A
	Novus Biologicals HSPA12A Antibody
	Abcam antibodies for HSPA12A
	Uscn Antibodies for HSPA12A
	ThermoFisher Antibodies for HSPA12A

Assay Products for HSPA12A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for HSPA12A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for HSPA12A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HSPA12A for domains About GeneDecksing

1 InterPro domain/family:

IPR026685 HSPA12

Graphical View of Domain Structure for InterPro Entry O43301

ProtoNet protein and cluster: O43301

UniProtKB/Swiss-Prot: HS12A_HUMAN, O43301

Similarity: Belongs to the heat shock protein 70 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005524	ATP binding	IEA	--

HSPA12A for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for HSPA12A:

Big cells

Increased homologous recombina

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for HSPA12A

miRNA Products:		OriGene 3'-UTR Clone: HSPA12A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPA12A
		8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate HSPA12A (see all 47):
		hsa-miR-345 hsa-miR-19b-2* hsa-miR-631 hsa-miR-10b* hsa-miR-1184 hsa-miR-378 hsa-miR-23a hsa-miR-761

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPA12A (see all 7) OriGene shRNA RFP: HSPA12A OriGene siRNA: HSPA12A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA12A
		Sirion Biotech Custom design and validation of potent shRNA sequences against HSPA12A

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for HSPA12A
			Sirion Biotech Customized adenovirus for overexpression of HSPA12A Sirion Biotech Customized adenovirus for potent knockdown of HSPA12A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HSPA12A (NM_025015)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPA12A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA12A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HSPA12A
		Search LifeMap BioReagents cell lines for HSPA12A
		Sirion Biotech Customized stable knockdown cell line services for HSPA12A Sirion Biotech Customized inducible knockdown cell line services for HSPA12A Sirion Biotech Customized stable overexpressing cell line services for HSPA12A Sirion Biotech Customized inducible overexpressing cell line services for HSPA12A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA12A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for HSPA12A

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5/743 Interacting proteins for HSPA12A (O43301^{2, 3} ENSP00000358211⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 743)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CDC5L	Q99459², ENSP00000360532⁴	MINT-7945693 MINT-7947479 STRING: ENSP00000360532
SNW1	Q13573², ENSP00000261531⁴	MINT-7945693 MINT-7947479 STRING: ENSP00000261531
NRCAM	Q92823³, ENSP00000368314⁴	I2D: score=2 STRING: ENSP00000368314
ABCF1	Q8NE71²	MINT-7945693 MINT-7947479
ABCF3	Q9NUQ8²	MINT-7945693 MINT-7947479

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for HSPA12A
Search CenterWatch for drugs/clinical trials and news about HSPA12A / HS12A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HSPA12A gene:

NM_025015.2

Unigene Cluster for HSPA12A:

Heat shock 70kDa protein 12A

Hs.648448 [show with all ESTs]

Unigene Representative Sequence: BC041412

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000369209(uc001lct.3 uc001lcu.3) ENST00000480802 ENST00000481291

ENST00000468935

miRNA Products:		OriGene 3'-UTR Clone: HSPA12A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSPA12A
		8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate HSPA12A (see all 47):
		hsa-miR-345 hsa-miR-19b-2* hsa-miR-631 hsa-miR-10b* hsa-miR-1184 hsa-miR-378 hsa-miR-23a hsa-miR-761

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPA12A (see all 7) OriGene shRNA RFP: HSPA12A OriGene siRNA: HSPA12A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA12A
		Sirion Biotech Custom design and validation of potent shRNA sequences against HSPA12A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: HSPA12A (NM_025015)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSPA12A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA12A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA12A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSPA12A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA12A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA12A

Additional cDNA sequence:

AB007877.1 AK092127.1 AK294672.1 AK294884.1 BC041412.2

10 DOTS entries:

DT.91654985 DT.415949 DT.95212944 DT.92423108 DT.121266282 DT.92423104 DT.70103489 DT.102825368

DT.102833658 DT.40108169

24/108 AceView cDNA sequences (see all 108):

AI760141 BQ876472 AI783610 BX477784 BQ717512 AI760152 BM712644 BQ722196

AL120441 AI124891 AA351039 CA448640 AB007877 BX280116 AA351210 N77058

BX955887 AA393528 AA398449 W81404 BU738372 BQ003691 BE048045 BQ182948

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HSPA12A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACCAATGTA

About this image

HSPA12A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

PureStem™ progenitor E68 (Embryonic Progenitor Cell)

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See HSPA12A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSPA12A

SOURCE GeneReport for Unigene cluster: Hs.648448

UniProtKB/Swiss-Prot: HS12A_HUMAN, O43301

Tissue specificity: Widely expressed with highest levels in brain, kidney and muscle

SABiosciences Expression via Pathway-Focused PCR Arrays including HSPA12A:

Cellular Stress Responses in human mouse rat

Heat Shock Proteins & Chaperones in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA12A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSPA12A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA12A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA12A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA12A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for HSPA12A gene from 4/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Hspa12a^{1 , 5}	heat shock protein 12A^{1, 5}	89.32(n)¹ 96.59(a)¹		19 (54.51 cM)⁵ 73442¹ NM_175199.3¹ NP_780408.1¹ 58795751⁵
chicken (Gallus gallus)	Aves	HSPA12A¹	heat shock 70kDa protein 12A	78.47(n) 89.71(a)		423917 XM_421779.3 XP_421779.3
lizard (Anolis carolinensis)	Reptilia	HSPA12A⁶	--	87(a)	1 ↔ 1	GL343206.1(1913720-1976782)
zebrafish (Danio rerio)	Actinopterygii	zgc:153612⁶ si:dkey-61p9.6⁶	si:dkey-61p9.6	81(a) 34(a)	1 ↔ 1 possible ortholog	17(21053107-21087268) 4(61390108-61418626)

ENSEMBL Gene Tree for HSPA12A (if available)
TreeFam Gene Tree for HSPA12A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for HSPA12A gene

HSPA12B²

1 SIMAP similar gene for HSPA12A using alignment to 3 protein entries: HS12A_HUMAN (see all proteins):

HSPA12B

HSPA12A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs146400404^1,2	--	118431599(+)	`AAGGCA/GGGAAA`	1	--	ut3¹		0	--	--	--	--
rs41284370^1,2	--	118431707(+)	`TTCTTC/TGACCC`	1	--	ut3¹		0	--	--	--	--
rs185367895^1,2	--	118431791(+)	`GGTCAA/GCGACC`	1	--	ut3¹		0	--	--	--	--
rs188746444^1,2	--	118431803(+)	`CTCAGC/GACACA`	1	--	ut3¹		0	--	--	--	--
rs41284372^1,2	--	118431822(+)	`CTTAGG/ATTGTT`	1	--	ut3¹		1		NA	120
rs181899316^1,2	--	118431919(+)	`GAATCC/TGTGAC`	1	--	ut3¹		0	--	--	--	--
rs184658924^1,2	--	118431952(+)	`AGAAGG/TGTCTG`	1	--	ut3¹		0	--	--	--	--
rs138118199^1,2	--	118432030(+)	`TGCTCA/GGTCTT`	1	--	ut3¹		0	--	--	--	--
rs149572382^1,2	--	118432037(+)	`TCTTGC/TGTACA`	1	--	ut3¹		0	--	--	--	--
rs144283218^1,2	--	118432038(+)	`CTTGCG/TTACAT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for HSPA12A (118430703 - 118502085 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for HSPA12A: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA12A

DNA2.0 Custom Variant and Variant Library Synthesis for HSPA12A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

HSPA12A for disorders           About GeneDecksing

OMIM gene information: 610701    OMIM disorders: --

1 disease for HSPA12A:    About MalaCards

schizophrenia

Human Genome Epidemiology (HuGE) Navigator: HSPA12A (2 documents)

Export disorders for HSPA12A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for HSPA12A gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with HSPA12A)

Utopia: connect your pdf to the dynamic
world of online information

Two Hsp70 family members expressed in atherosclerotic lesions. (PubMed id 12552099)^{1, 2, 3} Han Z.... Breslow J.L. (2003)
Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)^{1, 2} Ishikawa K....Ohara O. (1997)
Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia. (PubMed id 15601604)^{1, 9} Pongrac J.L....Mirnics K. (2004)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)¹ Starr J.M....Deary I.J. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)¹ Harris S.E....Deary I.J. (2007)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PubMed id 12421765)¹ Nakayama M....Ohara O. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 259217	HGNC: 19022	AceView: HSPA12A	Ensembl:ENSG00000165868	euGenes: HUgn259217
ECgene: HSPA12A	H-InvDB: HSPA12A

(According to HUGE)
About This Section

HUGE: KIAA0417

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for HSPA12A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for HSPA12A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for HSPA12A gene:
Search GeneIP for patents involving HSPA12A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for HSPA12A
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSPA12A		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSPA12A
	OriGene Protein Over-expression Lysate for HSPA12A		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for HSPA12A		OriGene 3'-UTR Clone for HSPA12A
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSPA12A
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for HSPA12A		OriGene Custom Protein Services for HSPA12A
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSPA12A
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSPA12A
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSPA12A
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSPA12A
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSPA12A
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSPA12A

	GenScript Custom Purified and Recombinant Proteins Services for HSPA12A		GenScript cDNA clones with any tag delivered in your preferred vector for HSPA12A
	GenScript Custom Assay Services for HSPA12A		GenScript Custom Superior Antibodies Services for HSPA12A
	GenScript Custom overexpressing Cell Line Services for HSPA12A		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in HSPA12A promoter
	Search Chromatin IP Primers for HSPA12A
	RT² qPCR Primer Assay in human, mouse, rat HSPA12A
	Search GNC Networks for HSPA12A
	SABiosciences PCR Arrays including human, mouse, rat HSPA12A

Search Tocris compounds for HSPA12A

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	HSPA12A antibodies
	HSPA12A lysates

	Antibodies for HSPA12A
	See all of Abcam's Antibodies, Kits and Proteins for HSPA12A
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

HSPA12A Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for HSPA12A

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSPA12A

	Browse SwitchGear 3'UTR luciferase reporter plasmids for HSPA12A
	Browse SwitchGear Promoter luciferase reporter plasmids for HSPA12A

ThermoFisher Antibodies for HSPA12A

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSPA12A

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for HSPA12A

Sirion Biotech Customized:

	stable knockdown cell line services for HSPA12A
	inducible knockdown cell line services for HSPA12A
	design and validation of potent shRNA sequences against HSPA12A
	adenovirus for potent knockdown of HSPA12A
	adenovirus for overexpression of HSPA12A
	stable overexpressing cell line services for HSPA12A
	inducible overexpressing cell line services for HSPA12A

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes HSPA12A gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

HSPA12A Gene

heat shock 70kDa protein 12A

Aliases
for HSPA12A gene

Summaries
for HSPA12A gene

Genomic Views
for HSPA12A gene

Proteins
for HSPA12A gene

Protein Domains /
Families
for HSPA12A gene

Function
for HSPA12A gene

Pathways & Interactions
for HSPA12A gene

Drugs & Compounds
for HSPA12A gene

Transcripts
for HSPA12A gene

Expression
for HSPA12A gene

Orthologs
for HSPA12A gene

Paralogs
for HSPA12A gene

Genomic Variants
for HSPA12A gene

Disorders / Diseases
for HSPA12A gene

Publications
for HSPA12A gene

External Searches for HSPA12A gene

Genome Databases showing HSPA12A gene

Other Databases showing HSPA12A gene

Specialized Databases showing HSPA12A gene

Intellectual Property
for HSPA12A gene

Products
for HSPA12A gene

View Random Gene

Advanced Search

Export list of displayed genes

HSPA12A Gene

heat shock 70kDa protein 12A

Aliasesfor HSPA12A gene

Summariesfor HSPA12A gene

Genomic Viewsfor HSPA12A gene

Proteinsfor HSPA12A gene

Protein Domains /Familiesfor HSPA12A gene

Functionfor HSPA12A gene

Pathways & Interactionsfor HSPA12A gene

Drugs & Compoundsfor HSPA12A gene

Transcriptsfor HSPA12A gene

Expression for HSPA12A gene

Orthologsfor HSPA12A gene

Paralogsfor HSPA12A gene

Genomic Variantsfor HSPA12A gene

Disorders / Diseasesfor HSPA12A gene

Publicationsfor HSPA12A gene

External Searches for HSPA12A gene

Genome Databases showing HSPA12A gene

Other Databases showing HSPA12A gene

Specialized Databases showing HSPA12A gene

Intellectual Propertyfor HSPA12A gene

Productsfor HSPA12A gene

View Random Gene

Aliases
for HSPA12A gene

Summaries
for HSPA12A gene

Genomic Views
for HSPA12A gene

Proteins
for HSPA12A gene

Protein Domains /
Families
for HSPA12A gene

Function
for HSPA12A gene

Pathways & Interactions
for HSPA12A gene

Drugs & Compounds
for HSPA12A gene

Transcripts
for HSPA12A gene

Expression
for HSPA12A gene

Orthologs
for HSPA12A gene

Paralogs
for HSPA12A gene

Genomic Variants
for HSPA12A gene

Disorders / Diseases
for HSPA12A gene

Publications
for HSPA12A gene

Intellectual Property
for HSPA12A gene

Products
for HSPA12A gene