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Aliases for HSP90B2P Gene

Aliases for HSP90B2P Gene

  • Heat Shock Protein 90 Beta Family Member 2, Pseudogene 2 3 5
  • Heat Shock Protein 90kDa Beta (Grp94), Member 2, Pseudogene 2 3
  • Tumor Rejection Antigen (Gp96) 1 Pseudogene 1 2 3
  • GRP94P1 3 4
  • GRP94b 3 4
  • TRAP1 3 4
  • Heat Shock Protein 90kDa Beta (Grp94), Member 1 Pseudogene 3
  • Heat Shock Protein 90kDa Beta Family Member 2, Pseudogene 3
  • Putative Heat Shock Protein 90 KDa Beta Member 2 4
  • Tumor Rejection Antigen (Gp96) Pseudogene 1 2
  • Heat Shock Protein 94b 3
  • HSPCP2 3
  • TRA1P1 3
  • HSP 3

External Ids for HSP90B2P Gene

Previous HGNC Symbols for HSP90B2P Gene

  • TRAP1
  • TRA1P1
  • HSPCP2

Previous GeneCards Identifiers for HSP90B2P Gene

  • GC15P097615
  • GC15P099797
  • GC15P075927

Summaries for HSP90B2P Gene

GeneCards Summary for HSP90B2P Gene

HSP90B2P (Heat Shock Protein 90 Beta Family Member 2, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90B2P Gene

  • Putative molecular chaperone.

Additional gene information for HSP90B2P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90B2P Gene

Genomics for HSP90B2P Gene

GeneHancer (GH) Regulatory Elements for HSP90B2P Gene

Promoters and enhancers for HSP90B2P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I099257 Enhancer 0.6 ENCODE 550.8 +0.1 68 1.1 RXRA MAX REST NR2F2 GABPA YY1 ZNF316 HNF4G ZBTB33 NFE2 HSP90B2P TTC23 SYNM LRRC28 HNRNPA1P62
GH15I099563 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 20.8 +308.9 308932 5.5 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 MEF2A ENSG00000259921 HSP90B2P CERS3-AS1 TTC23 LYSMD4 ENSG00000201724 GC15M099683
GH15I099253 Enhancer 0.6 Ensembl 0.8 -3.7 -3706 0.8 ZNF664 JUND GATA3 ZNF366 POLR2A IKZF1 NBN PRDM10 RCOR1 RUNX3 TTC23 LRRC28 HSP90B2P
GH15I099274 Enhancer 0.7 dbSUPER 0.4 +17.8 17844 1.3 PKNOX1 ZIC2 ZNF335 ZBTB48 PATZ1 SCRT2 ZNF600 ZNF189 L3MBTL2 OSR2 TTC23 LRRC28 SYNM HNRNPA1P62 HSP90B2P
GH15I099276 Enhancer 0.7 dbSUPER 0.4 +19.6 19645 2.3 PKNOX1 L3MBTL2 OSR2 ZFP69B ZNF335 PRDM6 ZNF610 ZNF692 ZBTB48 GLIS1 TTC23 LRRC28 MEF2A SYNM HNRNPA1P62 HSP90B2P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HSP90B2P on UCSC Golden Path with GeneCards custom track

Genomic Locations for HSP90B2P Gene

Genomic Locations for HSP90B2P Gene
chr15:99,257,525-99,260,276
(GRCh38/hg38)
Size:
2,752 bases
Orientation:
Plus strand
chr15:99,797,837-99,800,481
(GRCh37/hg19)

Genomic View for HSP90B2P Gene

Genes around HSP90B2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSP90B2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSP90B2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSP90B2P Gene

Proteins for HSP90B2P Gene

  • Protein details for HSP90B2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF3-ENPLL_HUMAN
    Recommended name:
    Putative endoplasmin-like protein
    Protein Accession:
    Q58FF3

    Protein attributes for HSP90B2P Gene

    Size:
    399 amino acids
    Molecular mass:
    45859 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSP90B2P Gene

Post-translational modifications for HSP90B2P Gene

No Post-translational modifications

No data available for DME Specific Peptides for HSP90B2P Gene

Domains & Families for HSP90B2P Gene

Protein Domains for HSP90B2P Gene

Suggested Antigen Peptide Sequences for HSP90B2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF3

UniProtKB/Swiss-Prot:

ENPLL_HUMAN :
  • Belongs to the heat shock protein 90 family.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90B2P: view

No data available for Gene Families for HSP90B2P Gene

Function for HSP90B2P Gene

Molecular function for HSP90B2P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone.

Gene Ontology (GO) - Molecular Function for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90B2P Gene

Localization for HSP90B2P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HSP90B2P Gene

Pathways & Interactions for HSP90B2P Gene

SuperPathways for HSP90B2P Gene

No Data Available

Interacting Proteins for HSP90B2P Gene

Selected Interacting proteins: Q58FF3-ENPLL_HUMAN for HSP90B2P Gene via IID

Gene Ontology (GO) - Biological Process for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90B2P Gene

Drugs & Compounds for HSP90B2P Gene

(1) Drugs for HSP90B2P Gene - From: ApexBio

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
AUY922 (NVP-AUY922) Pharma Potent Hsp90 inhibitor 0

(1) ApexBio Compounds for HSP90B2P Gene

Compound Action Cas Number
AUY922 (NVP-AUY922) Potent Hsp90 inhibitor 747412-49-3
genes like me logo Genes that share compounds with HSP90B2P: view

Drug Products

Transcripts for HSP90B2P Gene

mRNA/cDNA for HSP90B2P Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90B2P Gene

Heat shock protein 90kDa beta (Grp94), member 2, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90B2P Gene

No ASD Table

Relevant External Links for HSP90B2P Gene

GeneLoc Exon Structure for
HSP90B2P
ECgene alternative splicing isoforms for
HSP90B2P

Expression for HSP90B2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HSP90B2P Gene

mRNA expression in normal human tissues for HSP90B2P Gene

Protein differential expression in normal tissues from HIPED for HSP90B2P Gene

This gene is overexpressed in Lung (32.3) and Serum (27.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSP90B2P Gene



Protein tissue co-expression partners for HSP90B2P Gene

NURSA nuclear receptor signaling pathways regulating expression of HSP90B2P Gene:

HSP90B2P

SOURCE GeneReport for Unigene cluster for HSP90B2P Gene:

Hs.656611
genes like me logo Genes that share expression patterns with HSP90B2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HSP90B2P Gene

Orthologs for HSP90B2P Gene

Evolution for HSP90B2P Gene

ENSEMBL:
Gene Tree for HSP90B2P (if available)
TreeFam:
Gene Tree for HSP90B2P (if available)

No data available for Orthologs for HSP90B2P Gene

Paralogs for HSP90B2P Gene

(6) SIMAP similar genes for HSP90B2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90B2P: view

No data available for Paralogs for HSP90B2P Gene

Variants for HSP90B2P Gene

Sequence variations from dbSNP and Humsavar for HSP90B2P Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000064350 -- 99,260,721(+) T/C downstream_transcript_variant
rs1000782607 -- 99,260,618(+) G/T downstream_transcript_variant
rs1001095169 -- 99,259,147(+) G/T non_coding_transcript_variant
rs1001115158 -- 99,259,474(+) T/C non_coding_transcript_variant
rs1001550109 -- 99,260,410(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for HSP90B2P Gene

Variant ID Type Subtype PubMed ID
esv3637424 CNV gain 21293372
esv3892741 CNV gain 25118596
nsv1045124 CNV gain 25217958
nsv1055008 CNV gain 25217958
nsv570716 CNV gain 21841781
nsv977759 CNV duplication 23825009

Additional Variant Information for HSP90B2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HSP90B2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HSP90B2P Gene

Disorders for HSP90B2P Gene

Additional Disease Information for HSP90B2P

No disorders were found for HSP90B2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90B2P Gene

Publications for HSP90B2P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B … Monteiro A (Genomics 2005) 2 3 4 58
  2. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. (PMID: 25772364) Hendriks IA … Vertegaal AC (Cell reports 2015) 4 58
  3. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PMID: 23383273) Yu CC … Chow LP (PloS one 2013) 3 58
  4. Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94. (PMID: 8460400) Maki RG … Srivastava PK (Somatic cell and molecular genetics 1993) 22 58

Products for HSP90B2P Gene

Sources for HSP90B2P Gene

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