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Aliases for HSP90B2P Gene

Aliases for HSP90B2P Gene

  • Heat Shock Protein 90 Beta Family Member 2, Pseudogene 2 3 5
  • Heat Shock Protein 90kDa Beta (Grp94), Member 2, Pseudogene 2 3
  • Tumor Rejection Antigen (Gp96) 1 Pseudogene 1 2 3
  • GRP94P1 3 4
  • GRP94b 3 4
  • TRAP1 3 4
  • Heat Shock Protein 90kDa Beta (Grp94), Member 1 Pseudogene 3
  • Heat Shock Protein 90kDa Beta Family Member 2, Pseudogene 3
  • Putative Heat Shock Protein 90 KDa Beta Member 2 4
  • Tumor Rejection Antigen (Gp96) Pseudogene 1 2
  • Heat Shock Protein 94b 3
  • HSPCP2 3
  • TRA1P1 3
  • HSP 3

External Ids for HSP90B2P Gene

Previous HGNC Symbols for HSP90B2P Gene

  • TRAP1
  • TRA1P1
  • HSPCP2

Previous GeneCards Identifiers for HSP90B2P Gene

  • GC15P097615
  • GC15P099797
  • GC15P075927

Summaries for HSP90B2P Gene

GeneCards Summary for HSP90B2P Gene

HSP90B2P (Heat Shock Protein 90 Beta Family Member 2, Pseudogene) is a Pseudogene. GO annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90B2P Gene

  • Putative molecular chaperone.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90B2P Gene

Genomics for HSP90B2P Gene

Regulatory Elements for HSP90B2P Gene

Enhancers for HSP90B2P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G099253 0.7 Ensembl 0.7 -3.7 -3707 0.8 CTCF ESRRA MTA2 SIN3A CEBPG ZNF664 JUND GATA3 GATA2 ZNF366 TTC23 HSP90B2P LRRC28
GH15G099257 0.7 ENCODE 0.7 +0.1 68 1.1 CTCF MAX NR2F2 GABPA YY1 ZNF316 NCOR1 HNF4G HNF4A NFE2 TTC23 SYNM HSP90B2P HNRNPA1P62
GH15G099274 0.7 dbSUPER 0.4 +17.8 17845 1.3 PKNOX1 L3MBTL2 ZIC2 OSR2 ZFP69B ZNF610 ZNF692 ZBTB48 GLIS1 SCRT2 LRRC28 TTC23 SYNM HNRNPA1P62 HSP90B2P
GH15G099276 0.7 dbSUPER 0.4 +19.6 19646 2.3 PKNOX1 L3MBTL2 OSR2 ZFP69B PRDM6 ZNF610 ZNF692 ZBTB48 GLIS1 SCRT2 TTC23 LRRC28 MEF2A SYNM HNRNPA1P62 HSP90B2P
GH15G099283 0.8 FANTOM5 dbSUPER 0.3 +26.3 26275 0.4 ZNF146 MNT FOS TTC23 MEF2A HNRNPA1P62 HSP90B2P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HSP90B2P on UCSC Golden Path with GeneCards custom track

Genomic Location for HSP90B2P Gene

Chromosome:
15
Start:
99,257,525 bp from pter
End:
99,260,276 bp from pter
Size:
2,752 bases
Orientation:
Plus strand

Genomic View for HSP90B2P Gene

Genes around HSP90B2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSP90B2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSP90B2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSP90B2P Gene

Proteins for HSP90B2P Gene

  • Protein details for HSP90B2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF3-ENPLL_HUMAN
    Recommended name:
    Putative endoplasmin-like protein
    Protein Accession:
    Q58FF3

    Protein attributes for HSP90B2P Gene

    Size:
    399 amino acids
    Molecular mass:
    45859 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSP90B2P Gene

Post-translational modifications for HSP90B2P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for HSP90B2P Gene

Domains & Families for HSP90B2P Gene

Protein Domains for HSP90B2P Gene

Suggested Antigen Peptide Sequences for HSP90B2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF3

UniProtKB/Swiss-Prot:

ENPLL_HUMAN :
  • Belongs to the heat shock protein 90 family.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90B2P: view

No data available for Gene Families for HSP90B2P Gene

Function for HSP90B2P Gene

Molecular function for HSP90B2P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone.

Gene Ontology (GO) - Molecular Function for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90B2P Gene

Localization for HSP90B2P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HSP90B2P Gene

Pathways & Interactions for HSP90B2P Gene

SuperPathways for HSP90B2P Gene

No Data Available

Interacting Proteins for HSP90B2P Gene

Selected Interacting proteins: Q58FF3-ENPLL_HUMAN for HSP90B2P Gene via IID

Gene Ontology (GO) - Biological Process for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90B2P Gene

Drugs & Compounds for HSP90B2P Gene

(1) Drugs for HSP90B2P Gene - From: ApexBio

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
AUY922 (NVP-AUY922) Pharma Potent Hsp90 inhibitor 0

(1) ApexBio Compounds for HSP90B2P Gene

Compound Action Cas Number
AUY922 (NVP-AUY922) Potent Hsp90 inhibitor 747412-49-3
genes like me logo Genes that share compounds with HSP90B2P: view

Drug Products

Transcripts for HSP90B2P Gene

mRNA/cDNA for HSP90B2P Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90B2P Gene

Heat shock protein 90kDa beta (Grp94), member 2, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90B2P Gene

No ASD Table

Relevant External Links for HSP90B2P Gene

GeneLoc Exon Structure for
HSP90B2P
ECgene alternative splicing isoforms for
HSP90B2P

Expression for HSP90B2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HSP90B2P Gene

mRNA expression in normal human tissues for HSP90B2P Gene

Protein differential expression in normal tissues from HIPED for HSP90B2P Gene

This gene is overexpressed in Lung (32.3) and Serum (27.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSP90B2P Gene



Protein tissue co-expression partners for HSP90B2P Gene

NURSA nuclear receptor signaling pathways regulating expression of HSP90B2P Gene:

HSP90B2P

SOURCE GeneReport for Unigene cluster for HSP90B2P Gene:

Hs.656611
genes like me logo Genes that share expression patterns with HSP90B2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HSP90B2P Gene

Orthologs for HSP90B2P Gene

Evolution for HSP90B2P Gene

ENSEMBL:
Gene Tree for HSP90B2P (if available)
TreeFam:
Gene Tree for HSP90B2P (if available)

No data available for Orthologs for HSP90B2P Gene

Paralogs for HSP90B2P Gene

(6) SIMAP similar genes for HSP90B2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90B2P: view

No data available for Paralogs for HSP90B2P Gene

Variants for HSP90B2P Gene

Sequence variations from dbSNP and Humsavar for HSP90B2P Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000064350 -- 99,260,721(+) GATGT(C/T)AAAAT intron-variant, downstream-variant-500B
rs1000782607 -- 99,260,618(+) TATAT(G/T)ACAGC intron-variant, downstream-variant-500B
rs1001095169 -- 99,259,147(+) CTTAG(G/T)TTCCA intron-variant, nc-transcript-variant
rs1001115158 -- 99,259,474(+) CCCAA(C/T)TGGGT intron-variant, nc-transcript-variant
rs1001550109 -- 99,260,410(+) TTTCC(C/T)TGCAA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for HSP90B2P Gene

Variant ID Type Subtype PubMed ID
esv3637424 CNV gain 21293372
esv3892741 CNV gain 25118596
nsv1045124 CNV gain 25217958
nsv1055008 CNV gain 25217958
nsv570716 CNV gain 21841781
nsv977759 CNV duplication 23825009

Relevant External Links for HSP90B2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HSP90B2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HSP90B2P Gene

Disorders for HSP90B2P Gene

Relevant External Links for HSP90B2P

Genetic Association Database (GAD)
HSP90B2P
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSP90B2P

No disorders were found for HSP90B2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90B2P Gene

Publications for HSP90B2P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B. … Monteiro A. (Genomics 2005) 2 3 4 64
  2. SUMO-2 orchestrates chromatin modifiers in response to DNA damage. (PMID: 25772364) Hendriks I.A. … Vertegaal A.C. (Cell Rep. 2015) 4 64
  3. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PMID: 23383273) Yu C.C. … Chow L.P. (PLoS ONE 2013) 3 64
  4. Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94. (PMID: 8460400) Maki R.G. … Srivastava P.K. (Somat. Cell Mol. Genet. 1993) 22 64

Products for HSP90B2P Gene

Sources for HSP90B2P Gene

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