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Aliases for HSP90B2P Gene

Aliases for HSP90B2P Gene

  • Heat Shock Protein 90 Beta Family Member 2, Pseudogene 2 3 5
  • Heat Shock Protein 90kDa Beta (Grp94), Member 2, Pseudogene 2 3
  • Tumor Rejection Antigen (Gp96) 1 Pseudogene 1 2 3
  • GRP94P1 3 4
  • GRP94b 3 4
  • TRAP1 3 4
  • Heat Shock Protein 90kDa Beta (Grp94), Member 1 Pseudogene 3
  • Heat Shock Protein 90kDa Beta Family Member 2, Pseudogene 3
  • Putative Heat Shock Protein 90 KDa Beta Member 2 4
  • Tumor Rejection Antigen (Gp96) Pseudogene 1 2
  • Heat Shock Protein 94b 3
  • HSPCP2 3
  • TRA1P1 3
  • HSP 3

External Ids for HSP90B2P Gene

Previous HGNC Symbols for HSP90B2P Gene

  • TRAP1
  • TRA1P1
  • HSPCP2

Previous GeneCards Identifiers for HSP90B2P Gene

  • GC15P097615
  • GC15P099797
  • GC15P075927

Summaries for HSP90B2P Gene

GeneCards Summary for HSP90B2P Gene

HSP90B2P (Heat Shock Protein 90 Beta Family Member 2, Pseudogene) is a Pseudogene. GO annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90B2P Gene

  • Putative molecular chaperone.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90B2P Gene

Genomics for HSP90B2P Gene

Regulatory Elements for HSP90B2P Gene

Enhancers for HSP90B2P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F099257 0.7 ENCODE 0.8 +0.1 68 1.1 MAFG NR2F2 YY1 ZNF316 HNF4G NFE2 ZBTB33 MAFK ZNF652 EMSY TTC23 SYNM HSP90B2P HNRNPA1P62
GH15F099283 0.5 FANTOM5 0.3 +26.3 26275 0.4 ZNF146 MNT TTC23 MEF2A HNRNPA1P62 HSP90B2P
GH15F099284 0.4 Ensembl 0.3 +26.6 26576 0.2 ZNF146 MNT HNRNPA1P62 HSP90B2P
GH15F099279 0.2 Ensembl 0.3 +22.3 22276 0.4 SYNM HNRNPA1P62 HSP90B2P
GH15F099282 0.2 Ensembl 0.3 +24.8 24776 0.6 TTC23 SYNM HNRNPA1P62 HSP90B2P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around HSP90B2P on UCSC Golden Path with GeneCards custom track

Genomic Location for HSP90B2P Gene

Chromosome:
15
Start:
99,257,525 bp from pter
End:
99,260,276 bp from pter
Size:
2,752 bases
Orientation:
Plus strand

Genomic View for HSP90B2P Gene

Genes around HSP90B2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSP90B2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSP90B2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSP90B2P Gene

Proteins for HSP90B2P Gene

  • Protein details for HSP90B2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF3-ENPLL_HUMAN
    Recommended name:
    Putative endoplasmin-like protein
    Protein Accession:
    Q58FF3

    Protein attributes for HSP90B2P Gene

    Size:
    399 amino acids
    Molecular mass:
    45859 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HSP90B2P Gene

Post-translational modifications for HSP90B2P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for HSP90B2P Gene

Domains & Families for HSP90B2P Gene

Protein Domains for HSP90B2P Gene

Suggested Antigen Peptide Sequences for HSP90B2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF3

UniProtKB/Swiss-Prot:

ENPLL_HUMAN :
  • Belongs to the heat shock protein 90 family.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90B2P: view

No data available for Gene Families for HSP90B2P Gene

Function for HSP90B2P Gene

Molecular function for HSP90B2P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone.

Gene Ontology (GO) - Molecular Function for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90B2P Gene

Localization for HSP90B2P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HSP90B2P Gene

Pathways & Interactions for HSP90B2P Gene

SuperPathways for HSP90B2P Gene

No Data Available

Interacting Proteins for HSP90B2P Gene

Selected Interacting proteins: Q58FF3-ENPLL_HUMAN for HSP90B2P Gene via IID

Gene Ontology (GO) - Biological Process for HSP90B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
genes like me logo Genes that share ontologies with HSP90B2P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90B2P Gene

Drugs & Compounds for HSP90B2P Gene

(1) Drugs for HSP90B2P Gene - From: ApexBio

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
AUY922 (NVP-AUY922) Pharma Potent Hsp90 inhibitor 0

(1) ApexBio Compounds for HSP90B2P Gene

Compound Action Cas Number
AUY922 (NVP-AUY922) Potent Hsp90 inhibitor 747412-49-3
genes like me logo Genes that share compounds with HSP90B2P: view

Transcripts for HSP90B2P Gene

mRNA/cDNA for HSP90B2P Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90B2P Gene

Heat shock protein 90kDa beta (Grp94), member 2, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90B2P Gene

No ASD Table

Relevant External Links for HSP90B2P Gene

GeneLoc Exon Structure for
HSP90B2P
ECgene alternative splicing isoforms for
HSP90B2P

Expression for HSP90B2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HSP90B2P Gene

mRNA expression in normal human tissues for HSP90B2P Gene

Protein differential expression in normal tissues from HIPED for HSP90B2P Gene

This gene is overexpressed in Lung (32.3) and Serum (27.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSP90B2P Gene



Protein tissue co-expression partners for HSP90B2P Gene

NURSA nuclear receptor signaling pathways regulating expression of HSP90B2P Gene:

HSP90B2P

SOURCE GeneReport for Unigene cluster for HSP90B2P Gene:

Hs.656611
genes like me logo Genes that share expression patterns with HSP90B2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HSP90B2P Gene

Orthologs for HSP90B2P Gene

Evolution for HSP90B2P Gene

ENSEMBL:
Gene Tree for HSP90B2P (if available)
TreeFam:
Gene Tree for HSP90B2P (if available)

No data available for Orthologs for HSP90B2P Gene

Paralogs for HSP90B2P Gene

(6) SIMAP similar genes for HSP90B2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90B2P: view

No data available for Paralogs for HSP90B2P Gene

Variants for HSP90B2P Gene

Sequence variations from dbSNP and Humsavar for HSP90B2P Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1011041 -- 99,257,341(-) GGTTA(A/C)AAAGT intron-variant, upstream-variant-2KB
rs10152794 -- 99,260,493(+) TAGCT(A/G)CGATA intron-variant, downstream-variant-500B
rs111375923 -- 99,259,902(+) CGAAG(A/G)ACCTG intron-variant, nc-transcript-variant
rs111463153 -- 99,259,763(+) TGGTT(C/T)TGTTT intron-variant, nc-transcript-variant
rs112430754 -- 99,259,612(+) CAAGC(A/G)TACCA intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for HSP90B2P Gene

Variant ID Type Subtype PubMed ID
nsv977759 CNV duplication 23825009
nsv570716 CNV gain 21841781
nsv1055008 CNV gain 25217958
nsv1045124 CNV gain 25217958
esv3892741 CNV gain 25118596
esv3637424 CNV gain 21293372

Relevant External Links for HSP90B2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HSP90B2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HSP90B2P Gene

Disorders for HSP90B2P Gene

Relevant External Links for HSP90B2P

Genetic Association Database (GAD)
HSP90B2P
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSP90B2P

No disorders were found for HSP90B2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90B2P Gene

Publications for HSP90B2P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B. … Monteiro A. (Genomics 2005) 2 3 4 64
  2. SUMO-2 orchestrates chromatin modifiers in response to DNA damage. (PMID: 25772364) Hendriks I.A. … Vertegaal A.C. (Cell Rep. 2015) 4 64
  3. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PMID: 23383273) Yu C.C. … Chow L.P. (PLoS ONE 2013) 3 64
  4. Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94. (PMID: 8460400) Maki R.G. … Srivastava P.K. (Somat. Cell Mol. Genet. 1993) 22 64

Products for HSP90B2P Gene

Sources for HSP90B2P Gene

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