Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HSP90AB4P Gene

Aliases for HSP90AB4P Gene

  • Heat Shock Protein 90kDa Alpha Family Class B Member 4, Pseudogene 2 3 5
  • Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 4, Pseudogene 2 3
  • Heat Shock Protein 90Bd 3
  • HSP90Bd 3

External Ids for HSP90AB4P Gene

Previous GeneCards Identifiers for HSP90AB4P Gene

  • GC15M056770
  • GC15M058983
  • GC15M035805

Summaries for HSP90AB4P Gene

GeneCards Summary for HSP90AB4P Gene

HSP90AB4P (Heat Shock Protein 90kDa Alpha Family Class B Member 4, Pseudogene) is a Pseudogene. GO annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90AB4P Gene

  • Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90AB4P Gene

Genomics for HSP90AB4P Gene

Regulatory Elements for HSP90AB4P Gene

Enhancers for HSP90AB4P Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around HSP90AB4P on UCSC Golden Path with GeneCards custom track

Genomic Location for HSP90AB4P Gene

Chromosome:
15
Start:
58,690,473 bp from pter
End:
58,693,607 bp from pter
Size:
3,135 bases
Orientation:
Minus strand

Genomic View for HSP90AB4P Gene

Genes around HSP90AB4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSP90AB4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSP90AB4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSP90AB4P Gene

Proteins for HSP90AB4P Gene

  • Protein details for HSP90AB4P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF6-H90B4_HUMAN
    Recommended name:
    Putative heat shock protein HSP 90-beta 4
    Protein Accession:
    Q58FF6

    Protein attributes for HSP90AB4P Gene

    Size:
    505 amino acids
    Molecular mass:
    58264 Da
    Quaternary structure:
    • Homodimer.

neXtProt entry for HSP90AB4P Gene

Proteomics data for HSP90AB4P Gene at MOPED

Post-translational modifications for HSP90AB4P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for HSP90AB4P Gene

Domains & Families for HSP90AB4P Gene

Protein Domains for HSP90AB4P Gene

Suggested Antigen Peptide Sequences for HSP90AB4P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF6

UniProtKB/Swiss-Prot:

H90B4_HUMAN :
  • Belongs to the heat shock protein 90 family.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90AB4P: view

No data available for Gene Families for HSP90AB4P Gene

Function for HSP90AB4P Gene

Molecular function for HSP90AB4P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90AB4P Gene

Localization for HSP90AB4P Gene

Subcellular locations from UniProtKB/Swiss-Prot for HSP90AB4P Gene

Cytoplasm.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HSP90AB4P Gene

Pathways & Interactions for HSP90AB4P Gene

SuperPathways for HSP90AB4P Gene

No Data Available

Interacting Proteins for HSP90AB4P Gene

Gene Ontology (GO) - Biological Process for HSP90AB4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006950 response to stress IEA --
genes like me logo Genes that share ontologies with HSP90AB4P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90AB4P Gene

Drugs & Compounds for HSP90AB4P Gene

No Compound Related Data Available

Transcripts for HSP90AB4P Gene

mRNA/cDNA for HSP90AB4P Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90AB4P Gene

Heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90AB4P Gene

No ASD Table

Relevant External Links for HSP90AB4P Gene

GeneLoc Exon Structure for
HSP90AB4P
ECgene alternative splicing isoforms for
HSP90AB4P

Expression for HSP90AB4P Gene

Protein differential expression in normal tissues from HIPED for HSP90AB4P Gene

This gene is overexpressed in Breast (32.0) and Monocytes (11.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for HSP90AB4P Gene



SOURCE GeneReport for Unigene cluster for HSP90AB4P Gene Hs.670224

Protein tissue co-expression partners for HSP90AB4P Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HSP90AB4P Gene

Orthologs for HSP90AB4P Gene

Evolution for HSP90AB4P Gene

ENSEMBL:
Gene Tree for HSP90AB4P (if available)
TreeFam:
Gene Tree for HSP90AB4P (if available)

No data available for Orthologs for HSP90AB4P Gene

Paralogs for HSP90AB4P Gene

(10) SIMAP similar genes for HSP90AB4P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90AB4P: view

No data available for Paralogs for HSP90AB4P Gene

Variants for HSP90AB4P Gene

Structural Variations from Database of Genomic Variants (DGV) for HSP90AB4P Gene

Variant ID Type Subtype PubMed ID
nsv7266 OTHER Inversion 18451855
nsv904254 CNV Gain 21882294
nsv904269 CNV Loss 21882294
esv34110 CNV Loss 18971310

Relevant External Links for HSP90AB4P Gene

HapMap Linkage Disequilibrium report
HSP90AB4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HSP90AB4P Gene

Disorders for HSP90AB4P Gene

Relevant External Links for HSP90AB4P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSP90AB4P

No disorders were found for HSP90AB4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90AB4P Gene

Publications for HSP90AB4P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B. … Monteiro A. (Genomics 2005) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PMID: 23349634) Cloutier P. … Coulombe B. (PLoS Genet. 2013) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3

Products for HSP90AB4P Gene

Sources for HSP90AB4P Gene

Content