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Aliases for HSP90AB4P Gene

Aliases for HSP90AB4P Gene

  • Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 4, Pseudogene 2 3
  • Heat Shock Protein 90Bd 3
  • HSP90Bd 3

External Ids for HSP90AB4P Gene

Summaries for HSP90AB4P Gene

GeneCards Summary for HSP90AB4P Gene

HSP90AB4P (Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 4, Pseudogene) is a Pseudogene. GO annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90AB4P Gene

  • Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90AB4P Gene

Genomics for HSP90AB4P Gene

Genomic Location for HSP90AB4P Gene

Start:
58,690,473 bp from pter
End:
58,693,607 bp from pter
Size:
3,135 bases
Orientation:
Minus strand

Genomic View for HSP90AB4P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for HSP90AB4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HSP90AB4P Gene

Regulatory Elements for HSP90AB4P Gene

Proteins for HSP90AB4P Gene

  • Protein details for HSP90AB4P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF6-H90B4_HUMAN
    Recommended name:
    Putative heat shock protein HSP 90-beta 4
    Protein Accession:
    Q58FF6
    Secondary Accessions:

    Protein attributes for HSP90AB4P Gene

    Size:
    505 amino acids
    Molecular mass:
    58264 Da
    Quaternary structure:
    • Homodimer.

neXtProt entry for HSP90AB4P Gene

Proteomics data for HSP90AB4P Gene at MOPED

Post-translational modifications for HSP90AB4P Gene

No Post-translational modifications

No data available for DME Specific Peptides for HSP90AB4P Gene

Domains for HSP90AB4P Gene

Protein Domains for HSP90AB4P Gene

Suggested Antigen Peptide Sequences for HSP90AB4P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF6

UniProtKB/Swiss-Prot:

H90B4_HUMAN
Family:
  • Belongs to the heat shock protein 90 family.:
    • Q58FF6
genes like me logo Genes that share domains with HSP90AB4P: view

No data available for Gene Families for HSP90AB4P Gene

Function for HSP90AB4P Gene

Molecular function for HSP90AB4P Gene

UniProtKB/Swiss-Prot Function: Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

Gene Ontology (GO) - Molecular Function for HSP90AB4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90AB4P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for HSP90AB4P Gene

Localization for HSP90AB4P Gene

Subcellular locations from UniProtKB/Swiss-Prot for HSP90AB4P Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HSP90AB4P Gene COMPARTMENTS Subcellular localization image for HSP90AB4P gene
Compartment Confidence
cytosol 3
nucleus 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for HSP90AB4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with HSP90AB4P: view

Pathways for HSP90AB4P Gene

SuperPathways for HSP90AB4P Gene

No Data Available

Interacting Proteins for HSP90AB4P Gene

Gene Ontology (GO) - Biological Process for HSP90AB4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
genes like me logo Genes that share ontologies with HSP90AB4P: view

No data available for Pathways by source for HSP90AB4P Gene

Transcripts for HSP90AB4P Gene

mRNA/cDNA for HSP90AB4P Gene

(2) Additional mRNA sequences :

Unigene Clusters for HSP90AB4P Gene

Heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90AB4P Gene

No ASD Table

Relevant External Links for HSP90AB4P Gene

GeneLoc Exon Structure for
HSP90AB4P
ECgene alternative splicing isoforms for
HSP90AB4P

Expression for HSP90AB4P Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for HSP90AB4P Gene

SOURCE GeneReport for Unigene cluster for HSP90AB4P Gene Hs.670224

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for HSP90AB4P Gene

Orthologs for HSP90AB4P Gene

No data available for Orthologs and Evolution for HSP90AB4P Gene

Paralogs for HSP90AB4P Gene

Selected SIMAP similar genes for HSP90AB4P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90AB4P: view

No data available for Paralogs for HSP90AB4P Gene

Variants for HSP90AB4P Gene

Structural Variations from Database of Genomic Variants (DGV) for HSP90AB4P Gene

Variant ID Type Subtype PubMed ID
nsv7266 OTHER Inversion 18451855
nsv904254 CNV Gain 21882294
nsv904269 CNV Loss 21882294
esv34110 CNV Loss 18971310

Relevant External Links for HSP90AB4P Gene

HapMap Linkage Disequilibrium report
HSP90AB4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for HSP90AB4P Gene

Disorders for HSP90AB4P Gene

No disorders were found for HSP90AB4P Gene.

No data available for UniProtKB/Swiss-Prot for HSP90AB4P Gene

Publications for HSP90AB4P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B. … Monteiro A. (Genomics 2005) 2 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PMID: 23349634) Cloutier P. … Coulombe B. (PLoS Genet. 2013) 3

Products for HSP90AB4P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate HSP90AB4P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for HSP90AB4P
    • Block miRNA regulation of HSP90AB4P using miScript Target Protectors

    Sources for HSP90AB4P Gene

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