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Aliases for HSP90AB3P Gene

Aliases for HSP90AB3P Gene

  • Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 3, Pseudogene 2 3
  • Heat Shock 90kDa Protein 1, Beta Pseudogene 1 2 3
  • Heat Shock 90kD Protein 1, Beta Pseudogene 1 2 3
  • Heat Shock Protein 90Bc 3 4
  • HSP90BC 3 4
  • Heat Shock Protein 90-Beta C 4
  • HSPCP1 3

External Ids for HSP90AB3P Gene

Previous HGNC Symbols for HSP90AB3P Gene

  • HSPCP1

Previous GeneCards Identifiers for HSP90AB3P Gene

  • GC04P089031
  • GC04P088812

Summaries for HSP90AB3P Gene

GeneCards Summary for HSP90AB3P Gene

HSP90AB3P (Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 3, Pseudogene) is a Pseudogene. GO annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90AB3P Gene

  • Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90AB3P Gene

Genomics for HSP90AB3P Gene

Genomic Location for HSP90AB3P Gene

Chromosome:
4
Start:
87,891,748 bp from pter
End:
87,894,288 bp from pter
Size:
2,541 bases
Orientation:
Plus strand

Genomic View for HSP90AB3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for HSP90AB3P Gene

No data available for Regulatory Elements for HSP90AB3P Gene

Proteins for HSP90AB3P Gene

  • Protein details for HSP90AB3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF7-H90B3_HUMAN
    Recommended name:
    Putative heat shock protein HSP 90-beta-3
    Protein Accession:
    Q58FF7

    Protein attributes for HSP90AB3P Gene

    Size:
    597 amino acids
    Molecular mass:
    68325 Da
    Quaternary structure:
    • Homodimer.

neXtProt entry for HSP90AB3P Gene

Proteomics data for HSP90AB3P Gene at MOPED

Post-translational modifications for HSP90AB3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for HSP90AB3P Gene

Domains & Families for HSP90AB3P Gene

Protein Domains for HSP90AB3P Gene

Suggested Antigen Peptide Sequences for HSP90AB3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF7

UniProtKB/Swiss-Prot:

H90B3_HUMAN :
  • The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
  • Belongs to the heat shock protein 90 family.
Domain:
  • The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90AB3P: view

No data available for Gene Families for HSP90AB3P Gene

Function for HSP90AB3P Gene

Molecular function for HSP90AB3P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

Gene Ontology (GO) - Molecular Function for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90AB3P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90AB3P Gene

Localization for HSP90AB3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for HSP90AB3P Gene

Cytoplasm.

Gene Ontology (GO) - Cellular Components for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0070062 extracellular exosome IDA 23533145
genes like me logo Genes that share ontologies with HSP90AB3P: view

No data available for Subcellular locations from COMPARTMENTS for HSP90AB3P Gene

Pathways & Interactions for HSP90AB3P Gene

SuperPathways for HSP90AB3P Gene

No Data Available

Interacting Proteins for HSP90AB3P Gene

Gene Ontology (GO) - Biological Process for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HSP90AB3P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90AB3P Gene

Drugs & Compounds for HSP90AB3P Gene

No Compound Related Data Available

Transcripts for HSP90AB3P Gene

mRNA/cDNA for HSP90AB3P Gene

(1) Additional mRNA sequences :
(35) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90AB3P Gene

Heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90AB3P Gene

No ASD Table

Relevant External Links for HSP90AB3P Gene

GeneLoc Exon Structure for
HSP90AB3P
ECgene alternative splicing isoforms for
HSP90AB3P

Expression for HSP90AB3P Gene

mRNA expression in normal human tissues for HSP90AB3P Gene

Protein differential expression in normal tissues from HIPED for HSP90AB3P Gene

This gene is overexpressed in Plasma (17.8), Liver, secretome (13.8), Cervix (9.2), NK cells (8.7), and Peripheral blood mononuclear cells (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for HSP90AB3P Gene



SOURCE GeneReport for Unigene cluster for HSP90AB3P Gene Hs.744112

genes like me logo Genes that share expression patterns with HSP90AB3P: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for HSP90AB3P Gene

Orthologs for HSP90AB3P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for HSP90AB3P Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm6368 16
Species with no ortholog for HSP90AB3P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for HSP90AB3P Gene

ENSEMBL:
Gene Tree for HSP90AB3P (if available)
TreeFam:
Gene Tree for HSP90AB3P (if available)

Paralogs for HSP90AB3P Gene

(12) SIMAP similar genes for HSP90AB3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with HSP90AB3P: view

No data available for Paralogs for HSP90AB3P Gene

Variants for HSP90AB3P Gene

Structural Variations from Database of Genomic Variants (DGV) for HSP90AB3P Gene

Variant ID Type Subtype PubMed ID
nsv7364 OTHER Inversion 18451855

Relevant External Links for HSP90AB3P Gene

HapMap Linkage Disequilibrium report
HSP90AB3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HSP90AB3P Gene

Disorders for HSP90AB3P Gene

Relevant External Links for HSP90AB3P

Genetic Association Database (GAD)
HSP90AB3P
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HSP90AB3P
genes like me logo Genes that share disorders with HSP90AB3P: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90AB3P Gene

Publications for HSP90AB3P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B. … Monteiro A. (Genomics 2005) 2 67
  2. Assignment of an intron-containing human heat-shock protein gene (hsp90 beta, HSPCB) to chromosome 6 near TCTE1 (6p21) and two intronless pseudogenes to chromosomes 4 and 15 by polymerase chain reaction amplification from a panel of hybrid cell lines. (PMID: 8288256) Durkin A.S. … Nierman W.C. (Genomics 1993) 2 67
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  4. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. (PMID: 23533145) Principe S. … Drake R.R. (Proteomics 2013) 67
  5. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. (PMID: 23246001) Xu Y. … Ye Y. (Cell Rep 2012) 67

Products for HSP90AB3P Gene

Sources for HSP90AB3P Gene

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