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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

HSP90AA1 Gene

protein-coding GIFtS: 69
GCID: GC14M102547

Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member...

(Previous names: heat shock 90kD protein 1, alpha, heat shock 90kDa protein...)
(Previous symbols: HSPC1, HSPCA)

Microbiology & Infectious Diseases Congress

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1¹ ²		LAP2² ⁵
HSPC1¹ ² ³ ⁵		EL52²
HSPCA¹ ² ³ ⁵		HSP90N²
HSP90A² ³ ⁵		HSPCAL1²
Heat Shock 90kD Protein 1, Alpha¹ ²		HSPN²
Heat Shock 90kDa Protein 1, Alpha¹ ²		Hsp89²
Heat Shock 86 KDa² ³		Hsp90²
Renal Carcinoma Antigen NY-REN-38² ³		Epididymis Luminal Secretory Protein 52²
HSP86² ³		Heat Shock 90kD Protein 1, Alpha-Like 4²
HSP 86² ³		Heat Shock 90kD Protein, Alpha-Like 4²
HSP89A² ⁵		Heat Shock Protein HSP 90-Alpha²
HSPCAL4² ⁵

External Ids:	HGNC: 5253¹	Entrez Gene: 3320²	Ensembl: ENSG00000080824⁷	OMIM: 140571⁵	UniProtKB: P07900³

Export aliases for HSP90AA1 gene to outside databases

Previous GC identifer: GC14M101619

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for HSP90AA1 Gene:

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded

protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by

co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. (provided by

RefSeq, Jan 2012)

GeneCards Summary for HSP90AA1 Gene:

HSP90AA1 (heat shock protein 90kDa alpha (cytosolic), class A member 1) is a protein-coding gene. Diseases associated with HSP90AA1 include hand-foot-genital syndrome, and lobular neoplasia, and among its related super-pathways are NOD-like receptor signaling pathway and G2/M Transition. GO annotations related to this gene include protein homodimerization activity and identical protein binding. An important paralog of this gene is HSP90B1.

UniProtKB/Swiss-Prot: HS90A_HUMAN, P07900

Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of

specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a

functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the

client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate

its substrate recognition, ATPase cycle and chaperone function

summary for HSP90AA1 Gene:

Hsp90 (90 kDa heat shock protein) is a molecular chaperone that aids protein folding and quality control for

a large number of client proteins. Functional Hsp90 operates as dimer and has intrinsic ATPase activity. The

Hsp90 dimer acts in concert with other chaperones (e.g. Hsp70) and is regulated by a number of

co-chaperones/accessory proteins (e.g. Hop, cdc37). Hsp90 has been shown to interact with >100 proteins and

some notable clients include kinases (e.g. Raf-1), nuclear hormone receptors (e.g. estrogen receptors),

transcription factors (e.g. p53), GPCRs (e.g. CB2 receptors) and ion channels (e.g. CFTR). In humans, the

Hsp90beta isoform is constitutively expressed whereas the Hsp90alpha isoforms is expressed under stress

conditions. Hsp90 plays an important role in some tumor cell types by stabilising mutated oncogenic

proteins.

Gene Wiki entry for HSP90AA1 (Heat shock protein 90kDa alpha, member A1) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000014.8 NC_018925.2 NT_026437.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the HSP90AA1 gene promoter:
STAT1 p53 MyoD LCR-F1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): HSP90AA1 promoter sequence

Search SABiosciences Chromatin IP Primers for HSP90AA1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSP90AA1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33 Ensembl cytogenetic band: 14q32.31 HGNC cytogenetic band: 14q32.33

HSP90AA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSP90AA1 gene location

GeneLoc information about chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14M102547: view genomic region (about GC identifiers)

Start:	102,547,075 bp from pter	End:	102,606,086 bp from pter
Size:	59,012 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: HS90A_HUMAN, P07900 (See protein sequence)

Recommended Name: Heat shock protein HSP 90-alpha

Size: 732 amino acids; 84660 Da

Subunit: Homodimer. Interacts with AHSA1, FNIP1, HSF1, SMYD3 and TOM34. Interacts with TERT; the interaction,

together with PTGES3, is required for correct assembly and stabilization of the TERT holoenzyme complex.

Interacts with CHORDC1 and DNAJC7. Interacts with STUB1 and UBE2N; may couple the chaperone and ubiquitination

systems

Subcellular location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from

stage I to stage IV

6/162 PDB 3D structures from and Proteopedia for HSP90AA1 (see all 162):

1BYQ (3D)

1OSF (3D)

1UY6 (3D)

1UY7 (3D)

1UY8 (3D)

1UY9 (3D)

Secondary accessions: A8K500 B3KPJ9 Q2PP14 Q5CAQ6 Q5CAQ7 Q9BVQ5

Alternative splicing: 2 isoforms: P07900-1 P07900-2 (Variant in position: 71:M->L (in dbSNP:rs8005905))

Explore the universe of human proteins at neXtProt for HSP90AA1: NX_P07900

Explore proteomics data for HSP90AA1 at MOPED

Post-translational modifications:

UniProtKB: ISGylated

UniProtKB: S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_P07900

HSP90AA1 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (2 alternative transcripts):

NP_001017963.2 NP_005339.3

ENSEMBL proteins:

ENSP00000216281 ENSP00000335153 ENSP00000451400 ENSP00000450712 ENSP00000452241

ENSP00000396189

Reactome Protein details: P07900
Human Recombinant Protein Products for HSP90AA1:

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	Enzo Life Sciences proteins for HSP90AA1
	OriGene Purified Proteins for HSP90AA1 OriGene Protein Over-expression Lysate for HSP90AA1 OriGene MassSpec for HSP90AA1 OriGene Custom Protein Services for HSP90AA1
	GenScript Custom Purified and Recombinant Proteins Services for HSP90AA1
	Novus Biologicals HSP90AA1 Proteins Novus Biologicals HSP90AA1 Lysates
	Sino Biological Recombinant Protein for HSP90AA1 Browse Sino Biological Cell Lysates
	ProSpec Recombinant Protein for HSP90AA1
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 5/16 cellular component terms (GO ID links to tree view) (see all 16): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005622	intracellular	--	--
GO:0005737	cytoplasm	--	--
GO:0005829	cytosol	TAS	--
GO:0005886	plasma membrane	TAS	--

HSP90AA1 for ontologies About GeneDecksing

HSP90AA1 Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of HSP90AA1
	R&D Systems Antibodies for HSP90AA1 (HSP90 alpha)
	Cell Signaling Technology (CST) Antibodies for HSP90AA1 (HSP90A)
	OriGene Antibodies for HSP90AA1 OriGene Custom Antibody Services for HSP90AA1
	GenScript Custom Superior Antibodies Services for HSP90AA1
	Novus Biologicals HSP90AA1 Antibodies
	Abcam antibodies for HSP90AA1
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibody for HSP90AA1
	LSBio Antibodies in human, mouse, rat for HSP90AA1

Assay Products for HSP90AA1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for HSP90AA1
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for HSP90AA1
	Enzo Life Sciences assays for HSP90AA1
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

HSPC: Heat shock proteins / HSPC

5 InterPro protein domains:

IPR001404 Hsp90

IPR020575 Hsp90_N

IPR020568 Ribosomal_S5_D2-typ_fold

IPR003594 HATPase_ATP-bd

IPR019805 Heat_shock_protein_90_CS

Graphical View of Domain Structure for InterPro Entry P07900

ProtoNet protein and cluster: P07900

2 Blocks protein domains:

IPB001404 Heat shock protein Hsp90

IPB003594 ATP-binding region

UniProtKB/Swiss-Prot: HS90A_HUMAN, P07900

Domain: The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins like the

co-chaperone STUB1

Similarity: Belongs to the heat shock protein 90 family

HSP90AA1 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: HS90A_HUMAN, P07900

Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of

specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a

functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the

client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate

its substrate recognition, ATPase cycle and chaperone function

Gene Ontology (GO): 5/18 molecular function terms (GO ID links to tree view) (see all 18): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	TAS	11470816
GO:0002134	UTP binding	IEA	--
GO:0002135	CTP binding	IEA	--
GO:0003729	mRNA binding	IEA	--
GO:0005515	protein binding	IPI	12526792

HSP90AA1 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for HSP90AA1:

Wnt reporter upregulated

5 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Hsp90aa1):

cellular

endocrine/exocrine gland

immune system

mortality/aging

reproductive system

HSP90AA1 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-outs for HSP90AA1: Hsp90aa1^{tm1(KOMP)Wtsi} Hsp90aa1^tm1.1Udon

inGenious Targeting Laboratory - Custom generated mouse model solutions for HSP90AA1

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for HSP90AA1

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for HSP90AA1

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for HSP90AA1

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSP90AA1
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate HSP90AA1 (see all 16):
		hsa-miR-495 hsa-miR-361-5p hsa-miR-7-2* hsa-miR-589* hsa-miR-519e hsa-miR-3647-3p hsa-miR-570 hsa-miR-374a*

		SwitchGear 3'UTR luciferase reporter plasmid: HSP90AA1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for HSP90AA1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSP90AA1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for HSP90AA1
			Sirion Biotech Customized adenovirus for overexpression of HSP90AA1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for HSP90AA1 (see all 14) OriGene ORF clones in mouse, rat for HSP90AA1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): HSP90AA1 (NM_001017963)
		Sino Biological Human cDNA Clone for HSP90AA1
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSP90AA1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSP90AA1
		Sirion Biotech Customized lentivirus for stable overexpression of HSP90AA1 Customized lentivirus expression plasmids for stable overexpression of HSP90AA1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for HSP90AA1
		Search LifeMap BioReagents cell lines for HSP90AA1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSP90AA1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for HSP90AA1 About (see all 61)

See pathways by source

SuperPath

Contained pathways About

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

NOD-like receptor signaling pathway

0.37

NOD pathway

0.33

Recruitment of mitotic centrosome proteins and complexes

Recruitment of mitotic centrosome proteins and complexes	0.83	Mitotic G2-G2/M phases	0.81
Centrosome maturation	0.83	Loss of Nlp from mitotic centrosomes	0.78
G2/M Transition	0.83	Loss of proteins required for interphase microtubule organization,from the centrosome	0.78

Metabolism of nitric oxide

	Metabolism of nitric oxide	0.59			eNOS activation and regulation	0.59
	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	0.59			eNOS activation	0.41

Signaling by FGFR

Signaling by ERBB2

0.90

Signaling by EGFR in Cancer

0.83

Cell Cycle

Cell Cycle, Mitotic

0.84

Cell Cycle

0.84

Pathways by source See SuperPaths
Show all pathways

4 EMD Millipore Pathways for HSP90AA1

	Immune response Antigen presentation by MHC class I
	Development Glucocorticoid receptor signaling
	Selected targets of GCR-alpha
	Signal transduction AKT signaling

1 R&D Systems Pathway for HSP90AA1

Apoptosis Signaling Pathways

5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for HSP90AA1 (see all 11)

	Telomerase Components in Cell Signaling
	Androgen Signaling
	Glucocorticoid Receptor Signaling
	HIF1Alpha Pathway
	Aldosterone Signaling in Epithelial Cells

1 Cell Signaling Technology (CST) Pathway for HSP90AA1

Protein Stability

1 Tocris Bioscience Pathway for HSP90AA1

MAPK Pathway

5/6 GeneGo (Thomson Reuters) Pathways for HSP90AA1 (see all 6)

	Development VEGF signaling via VEGFR2 - generic cascades
	Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
	Signal transduction AKT signaling
	Immune response Antigen presentation by MHC class I
	CFTR folding and maturation (norm and CF)

5/19 BioSystems Pathways for HSP90AA1 (see all 19)

	EBV LMP1 signaling
	NOD pathway
	IL-6 Signaling Pathway
	TNF-alpha/NF-kB Signaling Pathway
	AhR pathway

5/28 Reactome Pathways for HSP90AA1 (see all 28)

	Developmental Biology
	Metabolism
	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
	Cell Cycle
	Recruitment of mitotic centrosome proteins and complexes

1 PharmGKB Pathway for HSP90AA1

Glucocorticoid Pathway (Peripheral Tissue), Pharmacodynamics

5/8 Kegg Pathways (Kegg details for HSP90AA1) (see all 8):

	Protein processing in endoplasmic reticulum
	PI3K-Akt signaling pathway
	Antigen processing and presentation
	NOD-like receptor signaling pathway
	Progesterone-mediated oocyte maturation

HSP90AA1 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for HSP90AA1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/1663 Interacting proteins for HSP90AA1 (P07900^{1, 2, 3} ENSP00000335153⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 1663)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ENSG00000237724	P08107³, ENSP00000406359⁴	I2D: score=2 STRING: ENSP00000406359
HSPA1A	P08107³, ENSP00000364802⁴	I2D: score=2 STRING: ENSP00000364802
ENSG00000212866	P08107³	I2D: score=2
ENSG00000215328	P08107³	I2D: score=2
ENSG00000224501	P08107³	I2D: score=2

About this table

Gene Ontology (GO): 5/28 biological process terms (GO ID links to tree view) (see all 28): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000086	G2/M transition of mitotic cell cycle	TAS	--
GO:0000278	mitotic cell cycle	TAS	--
GO:0001764	neuron migration	IEA	--
GO:0003009	skeletal muscle contraction	IEA	--
GO:0006200	ATP catabolic process	IDA	15937123

HSP90AA1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

HSP90AA1 for compounds About GeneDecksing

EMD Millipore small molecules for HSP90AA1:
Small Molecule - inhibitor

Browse drugs & compounds from Enzo Life Sciences

Compounds for HSP90AA1 available from Tocris Bioscience About this table

Compound	Action	CAS #
17-AAG	Selective Hsp90 inhibitor	[75747-14-7]
PU H71	Potent Hsp90 inhibitor	[873436-91-0]
Gedunin	Hsp90 inhibitor; exhibits anticancer and antimalarial activity	[2753-30-2]
Geldanamycin	Selective Hsp90 inhibitor	[30562-34-6]
Radicicol	Hsp90 inhibitor. Antifungal antibiotic	[12772-57-5]

10/45 DrugBank Compounds for HSP90AA1 (see all 45) About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Rifabutin	Ansatipin (see all 7)	72559-06-9	target	other/unknown	10701840 10919672 11306472 10759403 11358819
17-Dmag	--	--	target	--	17139284 17016423 10592235
4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid	--	--	target	--	17139284 17016423 10592235
4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole	--	--	target	--	17139284 17016423 10592235
Adenosine-5'-Diphosphate	--	20398-34-9	target	--	17139284 17016423
Geldanamycin	--	30562-34-6	target	--	17139284 17016423
Nedocromil	--	69049-73-6	target	--	12803546 17980980
(3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one	--	--	target	--	10592235
(5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime	--	--	target	--	10592235
2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol	--	--	target	--	10592235

10/113 Novoseek inferred chemical compound relationships for HSP90AA1 gene (see all 113) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
geldanamycin	97.9	855	12820659 (8), 16684877 (6), 15271357 (6), 19734938 (5) (see all 99)
17-(allylamino)-17-demethoxygeldanamycin	96.8	351	15841378 (5), 16634649 (4), 19082595 (4), 15057143 (3) (see all 99)
radicicol	95.8	209	9672245 (4), 10383157 (3), 15155759 (3), 15884943 (3) (see all 99)
17-amino-17-demethoxygeldanamycin	85.5	4	14571691 (1), 16854066 (1), 9890555 (1)
17-dmag	83.4	6	15338192 (4), 17088927 (1), 12725864 (1)
lbh-589	76	13	15514006 (2), 17876048 (2), 18070720 (1), 17699868 (1) (see all 7)
novobiocin	75.3	91	15209518 (8), 16421106 (5), 19935870 (4), 10945979 (4) (see all 36)
molybdate	70.4	37	10090774 (4), 9738900 (3), 16285732 (2), 15258137 (2) (see all 21)
steroid	67	202	8625242 (5), 9183567 (5), 9148915 (5), 10689618 (4) (see all 99)
herbimycin a	66.9	27	12145695 (3), 14698045 (1), 11007781 (1), 11360191 (1) (see all 21)

Search CenterWatch for drugs/clinical trials and news about HSP90AA1 / HS90A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for HSP90AA1 gene (2 alternative transcripts):

NM_001017963.2 NM_005348.3

Unigene Cluster for HSP90AA1:

Heat shock protein 90kDa alpha (cytosolic), class A member 1

Hs.525600 [show with all ESTs]

Unigene Representative Sequence: NM_001017963

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000216281(uc001ykx.1 uc001yku.4) ENST00000334701(uc001ykv.4)

ENST00000554401 ENST00000557089 ENST00000560130 ENST00000553585 ENST00000555662

ENST00000556554 ENST00000557234 ENST00000558600 ENST00000441629(uc001ykw.1)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat HSP90AA1
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate HSP90AA1 (see all 16):
		hsa-miR-495 hsa-miR-361-5p hsa-miR-7-2* hsa-miR-589* hsa-miR-519e hsa-miR-3647-3p hsa-miR-570 hsa-miR-374a*

		SwitchGear 3'UTR luciferase reporter plasmid: HSP90AA1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for HSP90AA1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSP90AA1

Clone Products:		OriGene clones in human, mouse for HSP90AA1 (see all 14) OriGene ORF clones in mouse, rat for HSP90AA1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): HSP90AA1 (NM_001017963)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for HSP90AA1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSP90AA1
		Sirion Biotech Customized lentivirus for stable overexpression of HSP90AA1 Customized lentivirus expression plasmids for stable overexpression of HSP90AA1

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for HSP90AA1
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSP90AA1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSP90AA1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSP90AA1

Additional mRNA sequence:

AF028832.1 AJ890082.1 AJ890083.1 AK056446.1 AK129557.1 AK291115.1 AK291607.1 AK300126.1

AK310595.1 BC000987.2 BC001695.2 BC007989.2 BC017233.2 BC023006.1 BC108695.1 BC121062.2

BX247955.1 BX248761.1 GQ149083.1 X07270.1 X15183.1

24/224 DOTS entries (see all 224):

DT.100849252 DT.91781494 DT.100658316 DT.100730414 DT.91845523 DT.95129185 DT.100730410 DT.100801571

DT.100730420 DT.98131982 DT.100680135 DT.100860129 DT.100730476 DT.92061474 DT.100730481 DT.100857433

DT.100730448 DT.100662911 DT.120782168 DT.97848044 DT.95378226 DT.100846879 DT.100730426 DT.100730485

24/2627 AceView cDNA sequences (see all 2627):

T16337 AA369744 BM751979 AA319049 BE772654 BM974105 BE793051 BI861290

BU153102 BM771890 BQ638075 BX444743 AI801059 CR607053 BM802957 BM456889

AA593911 BP354457 BP364931 AA309988 BM745750 BX429503 BC023006 BQ446823

GeneLoc Exon Structure

5/14 Alternative Splicing Database (ASD) splice patterns (SP) for HSP90AA1 (see all 14) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14a	·	14b	^	15a	·	15b	^
SP1:									-						-		-
SP2:																	-
SP3:																	-
SP4:
SP5:

ExUns:	16a	·	16b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for HSP90AA1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

HSP90AA1 expression in normal human tissues (normalized intensities) HSP90AA1 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TACTAGTCCT

About this image

HSP90AA1 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/10 selected tissues (see all 10) fully expand


Peripheral Nervous System (Nervous System)
spinal/ganglion/dorsal root ganglion

Kidney (Urinary System)
visceral organ/metanephros/renal cortex

Lower Urinary Tract (Urinary System)
visceral organ/metanephros/renal cortex

Neural Tube (Nervous System)
Spinal Ventral Columns

Heart (Cardiovascular System)
Atrioventricular Canal Cells Atrioventricular Canal

See HSP90AA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSP90AA1

SOURCE GeneReport for Unigene cluster: Hs.525600

SABiosciences Expression via Pathway-Focused PCR Arrays including HSP90AA1 (see all 18):

Antiviral Response in human mouse rat

Lymphoma in human mouse rat

Inflammasomes in human mouse rat

Autophagy in human mouse rat

T-cell & B-cell Activation in human mouse rat

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for HSP90AA1
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat HSP90AA1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSP90AA1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSP90AA1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSP90AA1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for HSP90AA1 gene from 8/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Hsp90aa1^{1 , 5}	heat shock protein 90, alpha (cytosolic), class A member more^{1, 5}	90.3(n)¹ 99.18(a)¹		12 (60.75 cM)⁵ 15519¹ NM_010480.5¹ NP_034610.1¹ 110690605⁵
chicken (Gallus gallus)	Aves	HSP90AA1¹	heat shock protein 90kDa alpha (cytosolic), class A more	82.37(n) 96.43(a)		423463 NM_001109785.1 NP_001103255.1
lizard (Anolis carolinensis)	Reptilia	-- HSP90AA1⁶	Uncharacterized protein	96(a) 82(a)	possible ortholog 1 ↔ 1	GL343232.1(1912641-1921714) GL343742.1(74458-74844)
zebrafish (Danio rerio)	Actinopterygii	AF068773.1²	--	77.42(n)		30591 AF068773.1
fruit fly (Drosophila melanogaster)	Insecta	Hsp83⁶	Heat shock protein 83	78(a)	1 → many	3L(3192969-3197059)
worm (Caenorhabditis elegans)	Secernentea	daf-21⁶	Heat shock protein 90	77(a)	1 → many	V(14684918-14688543)
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	HSC82(YMR186W)⁴ HSP82¹	Cytoplasmic chaperone of the Hsp90 family, redundant more⁴ Hsp82p¹	62.96(n)¹ 64.05(a)¹		13(632355-634472)⁴ 855836¹ NP_015084.1¹ 855224⁴ NP_013911.1⁴
thale cress (Arabidopsis thaliana)	eudicotyledons	HSP90.1¹	heat shock protein 81-1	66.81(n) 73.81(a)		835341 NM_124642.3 NP_200076.1

ENSEMBL Gene Tree for HSP90AA1 (if available)
TreeFam Gene Tree for HSP90AA1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for HSP90AA1 gene

HSP90B1² TRAP1² HSP90AB1²

14 SIMAP similar genes for HSP90AA1 using alignment to 8 protein entries: HS90A_HUMAN (see all proteins):

HSP90Af EL52 HSP90AA2 HSP90AB1 HSP90Be HSP90B1

HSP90AB3P TRA1 HSP90AB4P GRP94c HSP90B2P TRAP1

HSP90Bf HSP90AB2P

HSP90AA1 for paralogs About GeneDecksing

5/6 Pseudogenes.org Pseudogenes for HSP90AA1 (see all 6)
PGOHUM00000258562 PGOHUM00000245028 PGOHUM00000240280 PGOHUM00000259879 PGOHUM00000245768

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs67932321^1,2	C	--	82751808(+)	`TTTTT-/TT/TTT GAGAC`	1	--	int¹		1		NA	2
rs55683551^1,2	C	--	83556227(+)	`TTTTT-/TTT/TT TT/TTTTTGTGAC`	1	--	int¹		1		NA	2
rs2277466^1,2	C,F,H	--	102546600(+)	`CGAAGG/AGGATT`	2	--	int¹		8		EA NS	1648
rs8020653^1,2	C,F,H	--	102546637(+)	`CTAAAC/TGTGAT`	2	--	int¹		8		EA NS NA WA	444
rs11847709^1,2	C,F,H	--	102546812(+)	`CTAACC/GAAGTT`	2	--	int¹		9		NS EA NA WA	472
rs4906177^1,2	C,F,H	--	102546964(+)	`TGCAGT/CGCAAT`	2	--	int¹		14		NA WA CSA EA	377
rs189338142^1,2		--	102547014(+)	`TCAAGC/TGATTC`	2	--	int¹		0	--	--	--	--
rs191179135^1,2	C	--	102547064(+)	`GAACTA/TTGAGA`	2	--	int¹		0	--	--	--	--
rs139925232^1,2	C	--	102547085(+)	`CCAAGA/GAATTA`	2	--	ut3¹		0	--	--	--	--
rs184420805^1,2		--	102547092(+)	`ATTAAC/GTGACT`	2	--	ut3¹		0	--	--	--	--
rs1059629^1,2	C,F,H	--	102547105(-)	`CTGTGC/TTAAAT`	2	--	ut3¹		23		NA NS EA WA CSA	1791
rs150605311^1,2	C	--	102547184(+)	`GGGATC/GCATGT`	2	--	ut3¹		0	--	--	--	--
rs189791627^1,2		--	102547203(+)	`TTCCTA/GTTTTC`	2	--	ut3¹		0	--	--	--	--
rs1059623^1,2	C,F,H	--	102547218(-)	`GCACAT/CGTAGG`	2	--	ut3¹		15		MN NA WA CSA EA	561
rs181396530^1,2		--	102547222(+)	`CGTGTA/GCTCCA`	2	--	ut3¹		0	--	--	--	--
rs186947478^1,2	C	--	102547236(+)	`CACACA/CTGCTG`	2	--	ut3¹		0	--	--	--	--
rs115514898^1,2	C,F	--	102547305(+)	`GCTAGC/TGCCTC`	2	--	ut3¹		1		WA	118
rs34767631^1,2	F	--	102547331(-)	`ATGACAGTT/- AGTGC`	2	--	ut3¹		2		NS	88
rs34287031^1,2	C	--	102547373(-)	`GTGACA/CGTGTC`	2	--	ut3¹		2		NS	94
rs149779281^1,2		--	102547398(+)	`CTCATC/TTGTAT`	2	--	ut3¹		0	--	--	--	--
rs11547545^1,2	C,F	--	102547461(+)	`GACTGG/AGTCTG`	2	--	ut3¹ ese³		4		NS NA	98
rs190137720^1,2		--	102547480(+)	`TTGAAC/TAGCTT`	2	--	ut3¹		0	--	--	--	--
rs35754658^1,2	C,F	--	102547488(-)	`ATATCG/ATAAAG`	2	--	ut3¹		2		NS	94
rs186290063^1,2		--	102547490(+)	`TTACGA/TTATGC`	2	--	ut3¹		0	--	--	--	--
rs191117771^1,2		--	102547491(+)	`TACGAC/TATGCT`	2	--	ut3¹		0	--	--	--	--
rs11547531^1,2	C,F	--	102547602(-)	`AGTCCT/CCTAGA`	2	--	ut3¹ ese³		5		NA NS	100
rs1058078^1,2	C,F,A,H	--	102547648(-)	`CTTTTT/CGAACT`	2	--	ut3¹		17		MN NS EA NA CSA WA	1369
rs144076402^1,2	C	--	102547666(+)	`TACAAA/GATGTA`	2	--	ut3¹		0	--	--	--	--
rs182139510^1,2		--	102547671(+)	`GATGTA/GACGAA`	2	--	ut3¹		0	--	--	--	--
rs115690563^1,2	C,F	--	102547712(+)	`AACACT/GTCAAT`	2	--	ut3¹		1		WA	118
rs2298878^1,2	C,F,H	--	102547745(-)	`CAAGCC/TGGATG`	2	--	ut3¹ ese³		13		EA NA NS	2518
rs3831488^1,2	C,F	--	102547769(-)	`TTGTGTG/-GTCTA`	2	--	ut3¹		3		NS NA	96
rs72520876^1,2	C	--	102547770(+)	`AGACC-/AC/CA ACAAA`	4	--	ut3¹		2		CSA	4
rs200220551^1,2	C	--	102547774(-)	`TAACTG/TTGTGG`	2	--	ut3¹		0	--	--	--	--
rs146487565^1,2	C	--	102547816(+)	`TTACCC/TCAATC`	2	--	ut3¹		0	--	--	--	--
rs149051840^1,2		--	102547818(+)	`ACCCCA/CATCTG`	2	--	ut3¹		0	--	--	--	--
rs186085934^1,2		--	102547874(+)	`TTTAGA/TGCCTA`	2	--	ut3¹		0	--	--	--	--
rs116145388^1,2	C,F	--	102547927(+)	`CCTTAA/TAGTAG`	2	--	ut3¹		1		WA	118
rs35798224^1,2	C	--	102548006(-)	`ACAATT/GCCTCT`	2	--	ut3¹		3		NS WA	212
rs112417493^1,2	C	--	102548008(+)	`AGGAAC/TTGTAG`	2	--	ut3¹		1		CSA	2
rs143088106^1,2	C	--	102548026(+)	`AACAGC/GTAAGT`	2	--	ut3¹		0	--	--	--	--
rs202202735^1,2		--	102548033(+)	`AAGTCA/GTCCCT`	2	--	ut3¹		0	--	--	--	--
rs61999351^1,2	C,F	--	102548079(+)	`GTGTCG/ATCATC`	4	/D	syn¹		2		NS NA	4612
rs11547523^1,2	C,F,H	--	102548151(-)	`ATTGAT/CGAAGA`	4	/D	syn¹		20		NS EA NA WA EU	7753
rs191412997^1,2	C	--	102548161(+)	`TACCTA/GTTTCC`	2	--	int¹		0	--	--	--	--
rs56180359^1,2	C	--	102548206(+)	`AGCCAA/GCTATT`	2	--	int¹		0	--	--	--	--
rs55960360^1,2	C	--	102548221(+)	`TAATAC/TTCTTG`	2	--	int¹		0	--	--	--	--
rs2298877^1,2	C,F,A,H	--	102548224(-)	`AACCAA/GGAGTA`	2	--	int¹		36		EA NA NS EU WA CSA	4965
rs183194166^1,2		--	102548263(+)	`GACATA/GTGAGT`	2	--	int¹		0	--	--	--	--
rs188301098^1,2		--	102548264(+)	`ACATAA/TGAGTC`	2	--	int¹		0	--	--	--	--
rs142331193^1,2	C	--	102548300(+)	`GACCT-/TACTACTT`	2	--	cds¹		0	--	--	--	--
rs34766445^1,2	C,F	--	102548369(-)	`TTATCC/GAAACT`	2	--	int¹		2		NS	94
rs6575895^1,2	C,F,H	--	102548384(+)	`AAGTTT/CACCAT`	2	--	int¹		14		NS WA NA CSA EA	469
rs80020850^1,2	C	--	102548441(+)	`TATAAG/TGCTTA`	2	--	int¹		0	--	--	--	--
rs56205516^1,2	C	--	102548448(+)	`CTTACC/TCAGAC`	4	S G	mis¹		1		NA	4448
rs11547524^1,2	C,F	--	102548458(-)	`ATCAAA/GCTTGG`	4	K	syn¹		4		NA EU	6101
rs114622252^1,2	C,F	--	102548470(+)	`ATCCTG/ATAGAT`	4	/Y	syn¹		1		EA	206
rs36025350^1,2	C,F	--	102548485(-)	`ACACAT/CGCTAA`	4	/H	syn¹		6		NS WA NA EU	6369
rs35598057^1,2	C,F	--	102548545(-)	`GTCATC/TTTGCT`	4	I	syn¹		3		NS NA	4642
rs200207432^1,2		--	102548638(+)	`TCCAGC/GTGTTT`	4	H Q	mis¹		0	--	--	--	--
rs34644998^1,2	C,F	--	102548703(-)	`TGGAGA/CGAATC`	4	R	syn¹		7		NS NA EU	6261
rs191895590^1,2		--	102548740(+)	`GTGACA/TATACA`	4	I	syn¹		0	--	--	--	--
rs114789230^1,2		--	102548780(+)	`CAACCA/GCCTGT`	4	A V	mis¹		1		NA	214
rs34744920^1,2	C,F,H	--	102548791(-)	`ACTTTT/CTGATT`	2	--	int¹		4		NS NA	320
rs199656456^1,2	C	--	102548795(+)	`AAAAAA/GTGATG`	2	--	int¹		0	--	--	--	--
rs144274674^1,2	C	--	102548854(+)	`ATCTGC/TAGAAC`	2	--	int¹		0	--	--	--	--
rs182968443^1,2		--	102548945(+)	`TATAAC/TTTCAT`	2	--	int¹		0	--	--	--	--
rs187622667^1,2		--	102549142(+)	`TTAGTA/GGAGAC`	2	--	int¹		0	--	--	--	--
rs192647750^1,2		--	102549170(+)	`GCCAGA/GATGGT`	2	--	int¹		0	--	--	--	--
rs34955331^1,2	C,F	--	102549179(-)	`GAGATC/GGAGAC`	2	--	int¹		2		NS	94
rs10873530^1,2	C,F,A,H	--	102549231(+)	`GATTGT/CAGGCG`	2	--	int¹		11		NA NS WA CSA	117
rs189351877^1,2		--	102549236(+)	`CAGGCA/GTGAGC`	2	--	int¹		0	--	--	--	--
rs10782495^1,2	C,F,H	--	102549262(+)	`CACACG/AACATA`	2	--	int¹		15		NA NS WA CSA EA	477
rs192891267^1,2		--	102549277(+)	`TCTGTC/TTTAAG`	2	--	int¹		0	--	--	--	--
rs184575152^1,2		--	102549281(+)	`TTTTAA/GGTTGA`	2	--	int¹		0	--	--	--	--
rs188680586^1,2		--	102549287(+)	`GTTGAA/GAACAT`	2	--	int¹		0	--	--	--	--
rs201377395^1,2	C	--	102549337(+)	`TAGAAA/GTATCA`	2	--	int¹		0	--	--	--	--
rs200798258^1,2		--	102549354(+)	`AGGAAA/GTGCTG`	2	--	int¹		0	--	--	--	--
rs141409138^1,2	C	--	102549395(+)	`AATATA/C/GTCTTT`	6	D E	mis¹ syn¹		1		NA	4544
rs36078484^1,2	C,F	--	102549416(-)	`GAGAAC/TCTCTG`	4	N	syn¹		3		NS NA	4624
rs200169081^1,2	C	--	102549435(+)	`TTTTTC/TTCTCT`	4	K R	mis¹		0	--	--	--	--
rs181509556^1,2		--	102549436(+)	`TTTTTC/TCTCTT`	4	K E	mis¹		0	--	--	--	--
rs75630701^1,2	C	--	102549461(+)	`TCTTCA/TTCATC`	4	E D	mis¹		0	--	--	--	--
rs140941217^1,2	F	--	102549481(+)	`TTCCAG/AGCCTT`	4	/L	syn¹		1		NA	4508
rs11547543^1,2	C	--	102549564(-)	`CTATAA/C/TGATTG`	6	K T M	mis¹		1		NA	4550
rs186149423^1,2	C	--	102549611(+)	`AAGGCC/TGAGTT`	4	S	syn¹		0	--	--	--	--
rs36092445^1,2	C,F	--	102549679(-)	`TTCTTA/GACTGT`	2	--	int¹		3		NS EU	1415
rs11628272^1,2	H	--	102549825(+)	`CACCCA/CCAGAG`	2	--	int¹		0	--	--	--	--
rs77971024^1,2	F	--	102549826(+)	`ACCCAC/AAGAGC`	2	--	int¹		1		WA	118
rs7155973^1,2	C,F,H	--	102549839(+)	`ACAAGG/ATTGTA`	2	--	int¹		35		NS EA NA WA CSA EU	4280
rs189404188^1,2	C	--	102549851(+)	`GAACGA/TCGTGT`	2	--	int¹		0	--	--	--	--
rs200106034^1,2		--	102549863(+)	`TGACTA/GTAACA`	2	--	int¹		0	--	--	--	--
rs182005067^1,2	C	--	102549869(+)	`TAACAC/TAGTGT`	2	--	int¹		0	--	--	--	--
rs7156529^1,2	C,F	--	102549873(+)	`ATAGTG/ATTCTC`	2	--	int¹		7		NS NA WA EA EU	1773
rs201678802^1,2		--	102549916(+)	`CTCCTC/TCATTC`	4	K E	mis¹		0	--	--	--	--
rs201371540^1,2		--	102549941(+)	`TTGAGA/TGAAAC`	4	S	syn¹		0	--	--	--	--
rs114259343^1,2	C	--	102549968(+)	`GCAGAT/CGTGTA`	4	/T	syn¹		1		NA	214
rs140441571^1,2	C,F	--	102549971(+)	`GATGTG/ATAGTA`	4	/Y	syn¹		1		NA	4538
rs34913441^1,2	C,F	--	102549983(-)	`GAGCTG/ATTAAG`	4	/L	syn¹		5		NS WA NA	5008
rs78419996^1,2	C,F	--	102550070(+)	`GAATTT/AAAAAA`	2	--	int¹		2		NA	4
rs201811488^1,2		--	102550081(+)	`AAAAAA/CAAAAA`	2	--	int¹		0	--	--	--	--
rs35077536^1,2	C,F	--	102550086(-)	`TTAGTT/GTTTTT`	2	--	int¹		3		NS WA	96
rs200487784^1,2		--	102550108(+)	`GGAAAA/CCTAAT`	2	--	int¹		0	--	--	--	--
rs199542766^1,2		--	102550113(+)	`ACTAAC/TGGTTA`	2	--	int¹		0	--	--	--	--
rs34158504^1,2	C,F	--	102550121(-)	`GGTGTA/GAATAA`	2	--	int¹		3		NS WA	212
rs201315295^1,2		--	102550170(+)	`TGTAGC/TTCTCT`	4	N S	mis¹		0	--	--	--	--
rs190621788^1,2	C	--	102550172(+)	`TAGTTA/CTCTTT`	4	E D	mis¹		0	--	--	--	--
rs113261380^1,2	C,F	--	102550184(+)	`TCTTCC/TGCCAG`	4	A	syn¹		5		CSA WA NA EU	4463
rs180917872^1,2	C	--	102550333(+)	`AAATAC/TAAACC`	2	--	int¹		0	--	--	--	--
rs200835561^1,2	C,F	--	102550342(+)	`CCAAAT/CGCACT`	2	--	int¹		1		EU	977
rs145989749^1,2		--	102550384(+)	`TAAACC/TCCCAA`	2	--	int¹		0	--	--	--	--
rs35565517^1,2	C,F	--	102550402(-)	`TTCAGG/ATTATC`	2	--	int¹		3		NS WA	212
rs186243430^1,2		--	102550419(+)	`GGGACC/GTATTT`	2	--	int¹		0	--	--	--	--
rs190173547^1,2		--	102550516(+)	`AGCTGA/TTTTCA`	2	--	int¹		0	--	--	--	--
rs3742429^1,2	C,F,A,H	--	102550569(+)	`GTAGAA/GATGGG`	2	--	int¹		15		NS EA NA WA CSA	531
rs10135118^1,2	C,F,H	--	102550572(+)	`gagatG/Agggtt`	2	--	int¹		9		NS EA NA CSA	518
rs182839622^1,2		--	102550593(+)	`GCCCAA/GGCTGG`	2	--	int¹		0	--	--	--	--
rs34543198^1,2	C,F	--	102550704(-)	`CTGTCA/GCTGAT`	2	--	int¹		3		NS EU	1415
rs118043158^1,2	C	--	102550733(+)	`ATACTT/CACTCA`	2	--	int¹		2		NA EU	1441
rs4947^1,2	C,F,A,H	--	102550803(-)	`AACAAT/CATCAA`	4	/N	syn¹ ese³		25		MN NA NS WA CSA EA EU	7470
rs187480597^1,2		--	102550824(+)	`CTGTTC/TTCAAA`	4	E	syn¹		0	--	--	--	--
rs148861509^1,2	C	--	102550941(+)	`CAATGC/TATTAT`	2	--	int¹		0	--	--	--	--
rs75641214^1,2	C	--	102550999(+)	`TGAAG-/ATCACCC`	2	--	int¹		0	--	--	--	--
rs115927657^1,2	C,F	--	102551024(+)	`TTCACT/CGCCAA`	4	/A	syn¹		3		WA	558
rs190888868^1,2	C	--	102551057(+)	`AAGCTC/TTTATA`	4	K	syn¹		0	--	--	--	--
rs115566847^1,2	C,F	--	102551063(+)	`TTATAG/AAATTC`	4	/F	syn¹		1		WA	216
rs115513913^1,2	C	--	102551072(+)	`TCTCCG/ATACTC`	4	/Y	syn¹		2		NA	4726
rs115457506^1,2		--	102551083(+)	`CTCATT/GAGTAA`	4	/N /H	mis¹		1		EU	118
rs141494680^1,2	C,F	--	102551105(+)	`TTTCTG/AGTCCA`	4	/T	syn¹		2		NA EU	5873
rs55793809^1,2	C,F	--	102551163(+)	`TAATCT/ATCTTC`	4	/K /M	mis¹		2		WA NA	4760
rs199903835^1,2	C	--	102551244(+)	`CTTCCA/GACTCT`	4	S L	mis¹		0	--	--	--	--
rs55783428^1,2	C	--	102551262(+)	`CTTTTC/TCTTTT`	4	E G	mis¹		0	--	--	--	--
rs3832931^1,2	C	--	102551276(+)	`tcttc-/TTTgtctt`	2	--	cds¹		0	--	--	--	--
rs147326221^1,2	C,F	--	102551324(+)	`TCACGT/CTCCTT`	4	/E	syn¹		1		NA	4080
rs113172276^1,2	C	--	102551336(+)	`TCCACA/C/GTTCAA`	2	--	spa¹		1		CSA	1
rs141819961^1,2	C	--	102551359(+)	`AATCAC/TATCAC`	2	--	int¹		0	--	--	--	--
rs192140002^1,2	C	--	102551361(+)	`TCACAC/TCACTG`	2	--	int¹		0	--	--	--	--
rs377177954^1,2	C	--	102551386(+)	`TAAGCA/GACAGC`	2	--	int¹		0	--	--	--	--
rs184564544^1,2	C	--	102551597(+)	`ACCTAC/TAGACA`	2	--	int¹		0	--	--	--	--
rs147109489^1,2	C	--	102551775(+)	`TGCAAA/GAGAAG`	2	--	int¹		0	--	--	--	--
rs370510891^1,2	C	--	102551777(+)	`CAAGAA/C/GAAGAA`	2	--	int¹		0	--	--	--	--
rs138569377^1,2		--	102551783(+)	`AAGAAA/GGAAAA`	2	--	int¹		0	--	--	--	--
rs4586364^1,2	C,F	--	102551788(+)	`AGAAAA/GATTGA`	2	--	int¹ trp³		3		NS EU	1407
rs35308930^1,2	C,F	--	102551795(-)	`TATTATTA/-AGTCA`	2	--	cds¹		2		NS	90
rs145932708^1,2	C	--	102551796(+)	`GACTT-/TAAAATAC`	2	--	cds¹		0	--	--	--	--
rs59997574^1,2	C	--	102551797(+)	`TAATA-/ATACATTC`	2	--	cds¹		0	--	--	--	--
rs77536874^1,2	C	--	102551801(+)	`TAATAA/CATTCA`	2	--	int¹		0	--	--	--	--
rs141042198^1,2		--	102551854(+)	`TATAAA/TGCAAG`	2	--	int¹		0	--	--	--	--
rs35155249^1,2	C,F	--	102551929(-)	`GCGGTT/CCTTTT`	2	--	int¹		3		NS NA	214
rs34596136^1,2	C,F	--	102551949(-)	`GTAATG/TGCATG`	2	--	int¹		2		NS	94
rs34147314^1,2	C,F	--	102551950(-)	`TGTAAT/GGGCAT`	2	--	int¹		2		NS	94
rs35488162^1,2	C,F	--	102551955(-)	`ATTAGT/CGTAAT`	2	--	int¹		2		NS	94
rs55745202^1,2	C,F	--	102551985(+)	`CTGATC/TGTTGG`	2	--	int¹		1		EA	120
rs34014662^1,2	C,F	--	102552000(-)	`AGAATT/ATGTGT`	2	--	int¹		2		NS	94
rs35241778^1,2	C,F	--	102552030(-)	`TTGGAC/TCCCTG`	2	--	int¹		3		NS NA	214
rs189235249^1,2	C	--	102552077(+)	`CCAGTG/TAATGT`	2	--	int¹		0	--	--	--	--
rs201876874^1,2	C	--	102552089(+)	`CAGGTG/ACCTAC`	2	--	int¹		1		EU	1323
rs115967466^1,2		--	102552106(+)	`CTGTCC/TTCACT`	4	K R	mis¹		1		NA	214
rs115674612^1,2	C,F	--	102552132(+)	`GCTGAG/AGACTC`	4	/S	syn¹		3		EU NA	5917
rs148554342^1,2	F	--	102552144(+)	`CAAGCG/ATACTG`	4	/Y	syn¹		1		NA	4538
rs151160600^1,2	C	--	102552306(+)	`CCAAGG/ATTATT`	4	/N	syn¹		1		NA	4546
rs139051948^1,2	C,F	--	102552359(+)	`AGTGAG/AAGTTC`	4	/L /F	mis¹		1		NA	4548
rs116285249^1,2		--	102552447(+)	`TACCGG/AATTTT`	4	/I	syn¹		1		WA	218
rs185384696^1,2	C	--	102552472(+)	`AACAAA/GAAATA`	2	--	int¹		0	--	--	--	--
rs201132542^1,2	C	--	102552483(+)	`TTAATT/CTAAGC`	2	--	int¹		1		EU	973
rs149378258^1,2	C,F	--	102552490(+)	`AAGCAT/CACAGC`	2	--	int¹		1		EU	1013
rs3830965^1,2	C	--	102552502(-)	`AACTT-/CTTGGGGG`	2	--	int¹		0	--	--	--	--
rs146294148^1,2	C	--	102552537(+)	`TCTGGA/C/GTTAAT`	2	--	int¹		0	--	--	--	--
rs116476189^1,2	C,F	--	102552587(+)	`AGAAAG/AATCTC`	4	/I	syn¹		2		EA NA	430
rs201407591^1,2	C	--	102552644(+)	`ATTTCC/TGCCTG`	4	A	syn¹		0	--	--	--	--
rs11547538^1,2	C,F	--	102552656(-)	`ACGTTA/C/TGCCTT`	6	L F	mis¹ syn¹		1		NA	4550
rs141159161^1,2	C	--	102552684(+)	`CCATCG/AGTTGG`	4	/P /L	mis¹		1		NA	4548
rs180747051^1,2	C	--	102552722(+)	`TGGAAC/GGACAC`	2	--	int¹		0	--	--	--	--
rs200421140^1,2		--	102552743(+)	`TAAAAA/CCTTGC`	2	--	int¹		0	--	--	--	--
rs34721798^1,2	C	--	102552759(-)	`CCTCTG/CTAGAC`	2	--	int¹		2		NS	94
rs8004640^1,2	C,F,A	--	102552773(+)	`CACGAG/AATTCC`	2	--	int¹		9		NS WA NA CSA EA	460
rs3736807^1,2	C,F,H	--	102552775(-)	`ATGGAC/ATTTCG`	2	--	int¹		22		EA NS NA CSA WA	3915
rs36112665^1,2	C,F	--	102552856(-)	`TTTGTC/TAGCCG`	2	--	int¹		3		NS NA	212
rs185214387^1,2	C	--	102552932(+)	`AGGCCC/TGGGCC`	2	--	int¹		0	--	--	--	--
rs61992489^1,2	C	--	102553167(+)	`AGCGGG/TCCCGA`	2	--	int¹		3		NA	124
rs190032810^1,2		--	102553180(+)	`CCTCCA/GGAATA`	2	--	int¹		0	--	--	--	--
rs117339956^1,2	C,F	--	102553255(+)	`CTCCGC/TCCCGC`	2	--	int¹		1		EA	120
rs12323755^1,2		--	102553279(+)	`AGTCCC/TGGTCC`	2	--	int¹		0	--	--	--	--
rs185820610^1,2		--	102553303(+)	`ACAGGC/TCCCCA`	2	--	int¹		0	--	--	--	--
rs17554423^1,2	F	--	102553350(-)	`GTGCCG/ATTGGT`	2	--	int¹ ut5¹		2		MN EA	356
rs111677320^1,2	C	--	102553355(+)	`CGGCAC/GAGCCA`	2	--	int¹ ut5¹		0	--	--	--	--
rs2273655^1,2	F	--	102553364(-)	`GTCCCG/AGTGTG`	2	--	int¹ ut5¹		1		EA	1272
rs41438744^1,2	C,F	--	102553414(+)	`ATAGCG/CACGGG`	2	--	int¹ ut5¹		3		NA CSA WA	122
rs142800199^1,2		--	102553490(+)	`GCCGCA/CGCGGC`	2	--	int¹ ut5¹		0	--	--	--	--
rs17525734^1,2	C	--	102553626(-)	`CGCGGC/GGGCGT`	2	--	int¹ us2k¹		0	--	--	--	--
rs148703891^1,2	C	--	102553683(+)	`GGCGCC/TTTCTG`	2	--	int¹ us2k¹		0	--	--	--	--
rs17523505^1,2	C,F	--	102553841(-)	`CGCACG/TACCCT`	2	--	int¹ us2k¹		3		MN EA WA	474
rs142162345^1,2		--	102553844(+)	`GTCGTC/GCGTGG`	2	--	int¹ us2k¹		0	--	--	--	--
rs150774709^1,2		--	102553852(+)	`TGGACC/GGAGAG`	2	--	int¹ us2k¹		0	--	--	--	--
rs111482627^1,2	C,F	--	102553906(+)	`CCTGAG/CTGGCG`	2	--	int¹ us2k¹		1		NA	2
rs190327978^1,2		--	102553927(+)	`TGCCAA/GAGAAT`	2	--	int¹ us2k¹		0	--	--	--	--
rs183687034^1,2		--	102554034(+)	`CGCTCA/GGGGAT`	2	--	int¹ us2k¹		0	--	--	--	--
rs115452353^1,2	C	--	102554040(+)	`GGGATC/TCTCCA`	2	--	int¹ us2k¹		0	--	--	--	--
rs188655712^1,2		--	102554124(+)	`CCTTAC/GCTTGG`	2	--	int¹ us2k¹		0	--	--	--	--
rs11623605^1,2	C,H	--	102554286(+)	`TTTTTC/TTCTTT`	2	--	int¹ us2k¹ trp³		2		NA CSA	4
rs56115840^1,2	C	--	102554288(+)	`TTTTTC/TTTTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs60182473^1,2	C,F	--	102554345(+)	`GCGGCG/AGAATC`	2	--	int¹ us2k¹		2		WA	120
rs147596946^1,2		--	102554394(+)	`ATCCTC/TCCGCC`	2	--	int¹ us2k¹		0	--	--	--	--
rs116937205^1,2	C,F	--	102554410(+)	`TTTCCC/AAGTAG`	2	--	int¹ us2k¹		1		NA	120
rs72698521^1,2	C,F	--	102554449(+)	`GGCGCG/CGACAC`	2	--	int¹ us2k¹		1		NA	120
rs201925926^1,2	C	--	102554456(+)	`GACAC-/ACACCT`	2	--	int¹ us2k¹		0	--	--	--	--
rs4906178^1,2	C,F,A,H	--	102554552(+)	`GATATC/TTTGGC`	2	--	int¹ us2k¹		24		NS EA NA WA CSA	2351
rs140272566^1,2	C	--	102554634(+)	`TCTTCC/TTCTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs144250673^1,2	C	--	102554721(+)	`CTTGCC/GGTGTA`	2	--	int¹ us2k¹		0	--	--	--	--
rs192355704^1,2		--	102554739(+)	`GATGGA/CACTAC`	2	--	int¹ us2k¹		0	--	--	--	--
rs116628428^1,2	C,F	--	102554753(+)	`CGCTTC/TCTGGT`	2	--	int¹ us2k¹		1		WA	118
rs4906179^1,2	C,F,A,H	--	102554761(+)	`GGTCTC/TTAGGG`	2	--	int¹ us2k¹		19		NS NA WA CSA EA	1840
rs145402512^1,2		--	102554790(+)	`AGCAGA/GGGTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs3809386^1,2	C,F,A,H	--	102554791(-)	`AAAACG/CCCTGC`	2	--	int¹ us2k¹		10		NA WA CSA EA	371
rs182508904^1,2		--	102554831(+)	`CGTGTA/GAAATC`	2	--	int¹ us2k¹		0	--	--	--	--
rs186902442^1,2		--	102554900(+)	`CACGTA/GGCGCG`	2	--	int¹ us2k¹		0	--	--	--	--
rs3809385^1,2	C	--	102554925(-)	`ACACCC/GGGTCA`	2	--	int¹ us2k¹		0	--	--	--	--
rs143317149^1,2		--	102554938(+)	`GCCTGC/GTCCTG`	2	--	int¹ us2k¹		0	--	--	--	--
rs191768351^1,2	C	--	102554969(+)	`GGGGGC/TGCGCC`	2	--	int¹ us2k¹		0	--	--	--	--
rs199510100^1,2	C	--	102555018(-)	`ATTCCC/TCCCCG`	2	--	int¹ us2k¹		0	--	--	--	--
rs75981586^1,2	F	--	102555178(+)	`CATTGC/TCCAGG`	2	--	int¹ us2k¹		1		WA	118
rs200193929^1,2		--	102555246(+)	`TTCTT-/TTCTTTTT`	2	--	cds¹		0	--	--	--	--
rs201718334^1,2		--	102555247(+)	`TCTTT-/TCTTTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs67792277^1,2	C	--	102555249(+)	`TTTTT-/CTTTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs112880950^1,2	C	--	102555249(+)	`CTTTTC/TTTTTT`	2	--	int¹ us2k¹		0	--	--	--	--
rs184008070^1,2		--	102555270(+)	`AAAGTC/TTCACT`	2	--	int¹ us2k¹		0	--	--	--	--
rs199954822^1,2		--	102555312(+)	`AATCT-/CTGCTC ACTGCAACCTGCT`	2	--	int¹ us2k¹		0	--	--	--	--
rs187185989^1,2		--	102555344(+)	`CCTCTA/GCCTCC`	2	--	int¹ us2k¹		0	--	--	--	--
rs192850236^1,2		--	102555418(+)	`ACGCCC/TGGCTA`	2	--	int¹ us2k¹		0	--	--	--	--
rs10151188^1,2	C,F,H	--	102555500(+)	`TGATCC/TGCCCG`	2	--	int¹ us2k¹		1		NS	118
rs145683436^1,2		--	102555593(+)	`GGACCG/TTCATT`	1	--	int¹		0	--	--	--	--
rs185351429^1,2		--	102555700(+)	`CCCTTC/TTTCCT`	1	--	int¹		0	--	--	--	--
rs142762948^1,2		--	102555707(+)	`TCCTTC/TCACAA`	1	--	int¹		0	--	--	--	--
rs190331005^1,2		--	102556034(+)	`GCTTCA/CCCCCT`	1	--	int¹		0	--	--	--	--
rs182504551^1,2		--	102556075(+)	`CAGGTC/TACTGA`	1	--	int¹		0	--	--	--	--
rs183621452^1,2		--	102556216(+)	`GTCAGC/TTCACC`	1	--	int¹		0	--	--	--	--
rs145023934^1,2		--	102556340(+)	`CCCACC/GCTCTG`	1	--	int¹		0	--	--	--	--
rs188322298^1,2		--	102556349(+)	`TGCAAA/GTTCTA`	1	--	int¹		0	--	--	--	--
rs138625073^1,2		--	102556405(+)	`TGTGAC/GGCCCT`	1	--	int¹		0	--	--	--	--
rs149325494^1,2		--	102556461(+)	`TCCTAC/TTTCTG`	1	--	int¹		0	--	--	--	--
rs144527890^1,2	C	--	102556474(+)	`TCTGGC/TGCACT`	1	--	int¹		0	--	--	--	--
rs79325709^1,2	C,F	--	102556577(+)	`ATCTTC/TTGCTC`	1	--	int¹		1		WA	118
rs11621560^1,2	C,F,A,H	--	102556743(+)	`TTCACA/CGCCTT`	1	--	int¹		36		NS EA EU NA WA CSA	3929
rs11331617^1,2	C,F	--	102556810(+)	`AGACGG/-AGTCT`	1	--	int¹		4		NA CSA	8
rs148450554^1,2	C	--	102556869(+)	`ACAAGC/TTCCGC`	1	--	int¹		0	--	--	--	--
rs180865155^1,2		--	102556872(+)	`AGCTCC/TGCCTC`	1	--	int¹		0	--	--	--	--
rs143655920^1,2		--	102556879(+)	`CCTCCC/TGGGTT`	1	--	int¹		0	--	--	--	--
rs147165071^1,2		--	102556929(+)	`CTACAC/GGCGCC`	1	--	int¹		0	--	--	--	--
rs140441452^1,2		--	102556931(+)	`ACAGGC/TGCCCG`	1	--	int¹		0	--	--	--	--
rs144157373^1,2		--	102556936(+)	`CGCCCA/GCCACC`	1	--	int¹		0	--	--	--	--
rs61992490^1,2	F	--	102556947(+)	`ACACCC/TGGCTA`	1	--	int¹		1		NA	2
rs139958925^1,2		--	102556974(+)	`AAGTAC/GAGAGG`	1	--	int¹		0	--	--	--	--
rs150148758^1,2		--	102556997(+)	`GTTAGC/TCAGGA`	1	--	int¹		0	--	--	--	--
rs145884772^1,2		--	102557089(+)	`GGCCTC/TAACAA`	1	--	int¹		0	--	--	--	--
rs185268533^1,2		--	102557327(+)	`TTTCTA/GTGCAT`	1	--	int¹		0	--	--	--	--
rs189924388^1,2		--	102557339(+)	`CAGTTA/CAGTAT`	1	--	int¹		0	--	--	--	--
rs145846796^1,2		--	102557443(+)	`TACCCC/TATAGC`	1	--	int¹		0	--	--	--	--
rs77787008^1,2	C,F	--	102557484(+)	`AGCAGG/ACTAGC`	1	--	int¹		1		WA	118
rs181518686^1,2		--	102557621(+)	`CTCCAC/GGGCAG`	1	--	int¹		0	--	--	--	--
rs187107179^1,2		--	102557636(+)	`ACCCAC/GGTCTG`	1	--	int¹		0	--	--	--	--
rs146574833^1,2	C	--	102557783(+)	`GGTGAA/TACCCC`	1	--	int¹		0	--	--	--	--
rs117913730^1,2	C,F	--	102557813(+)	`AAAAAT/GTTAGC`	1	--	int¹		1		NA	120
rs141304520^1,2		--	102557846(+)	`TAGTCC/TCAGCT`	1	--	int¹		0	--	--	--	--
rs201473376^1,2		--	102557965(+)	`CAAAA-/AAAC AAACA`	1	--	int¹		0	--	--	--	--
rs191891907^1,2		--	102557973(+)	`CAAACA/CAACAA`	1	--	int¹		0	--	--	--	--
rs184234228^1,2		--	102558034(+)	`ACATGC/GTTCAC`	1	--	int¹		0	--	--	--	--
rs28571830^1,2	C,F	--	102558123(+)	`CACACC/TCAGCT`	1	--	int¹		2		WA NA	238
rs143214911^1,2		--	102558181(+)	`CTGGTC/GTTGAA`	1	--	int¹		0	--	--	--	--
rs186468908^1,2		--	102558233(+)	`TGCTGA/GGATTA`	1	--	int¹		0	--	--	--	--
rs189664003^1,2		--	102558243(+)	`ACAGGC/TGTGAG`	1	--	int¹		0	--	--	--	--
rs138036085^1,2	C	--	102558359(+)	`TTTAC-/ATGTTTT`	1	--	int¹		0	--	--	--	--
rs77669806^1,2	C,F	--	102558433(+)	`CAGTCC/TCGCTC`	1	--	int¹		1		EA	120
rs7156564^1,2	C,F	--	102558588(+)	`tttttG/Agtaga`	1	--	int¹		8		NA WA CSA EA	252
rs117058023^1,2	F	--	102558660(+)	`GCCTCG/TGTGTC`	1	--	int¹		1		NA	120
rs182376157^1,2		--	102558715(+)	`ATTTCC/TAATAT`	1	--	int¹		0	--	--	--	--
rs7158241^1,2	C,F	--	102558726(+)	`ttaatT/Gccatt`	1	--	int¹		2		WA	120
rs116802223^1,2	F	--	102558808(+)	`TATGGT/ACTATT`	1	--

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HSP90AA1 Gene

Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member...

Aliases
for HSP90AA1 gene

Summaries
for HSP90AA1 gene

Genomic Views
for HSP90AA1 gene

Proteins
for HSP90AA1 gene

Protein Domains /
Families
for HSP90AA1 gene

Function
for HSP90AA1 gene

Pathways & Interactions
for HSP90AA1 gene

Drugs & Compounds
for HSP90AA1 gene

Transcripts
for HSP90AA1 gene

Expression
for HSP90AA1 gene

Orthologs
for HSP90AA1 gene

Paralogs
for HSP90AA1 gene

Genomic Variants
for HSP90AA1 gene

Advanced Search

Export list of displayed genes

HSP90AA1 Gene

Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member...

Aliasesfor HSP90AA1 gene

Summariesfor HSP90AA1 gene

Genomic Viewsfor HSP90AA1 gene

Proteinsfor HSP90AA1 gene

Protein Domains /Familiesfor HSP90AA1 gene

Functionfor HSP90AA1 gene

Pathways & Interactionsfor HSP90AA1 gene

Drugs & Compoundsfor HSP90AA1 gene

Transcriptsfor HSP90AA1 gene

Expression for HSP90AA1 gene

Orthologsfor HSP90AA1 gene

Paralogsfor HSP90AA1 gene

Genomic Variantsfor HSP90AA1 gene

Aliases
for HSP90AA1 gene

Summaries
for HSP90AA1 gene

Genomic Views
for HSP90AA1 gene

Proteins
for HSP90AA1 gene

Protein Domains /
Families
for HSP90AA1 gene

Function
for HSP90AA1 gene

Pathways & Interactions
for HSP90AA1 gene

Drugs & Compounds
for HSP90AA1 gene

Transcripts
for HSP90AA1 gene

Expression
for HSP90AA1 gene

Orthologs
for HSP90AA1 gene

Paralogs
for HSP90AA1 gene

Genomic Variants
for HSP90AA1 gene