HSD3B7 Gene
protein-coding GIFtS: 55
GCID: GC16P030997
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|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid...
| |
Aliases
for HSD3B7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase71 2 | | PFIC42 5 | | C(27)-3BETA-HSD1 2 | | 3 Beta-Hydroxy-Delta 5-C27-Steroid Oxidoreductase2 | | SDR11E31 2 | | 3 Beta-Hydroxysteroid Dehydrogenase Type 72 | | C(27) 3-Beta-HSD2 3 | | CBAS12 | | Cholest-5-Ene-3-Beta,7-Alpha-Diol 3-Beta-Dehydrogenase2 3 | | Short Chain Dehydrogenase/Reductase Family 11E, Member 32 | | 3 Beta-Hydroxysteroid Dehydrogenase Type VII2 3 | | EC 1.1.1.-3 | | 3-Beta-HSD VII2 3 | | EC 1.1.1.1813 | | 3-Beta-Hydroxy-Delta(5)-C27 Steroid Oxidoreductase2 3 | | |
Export aliases for HSD3B7 gene to outside databasesPrevious GC identifers: GC16P031493 GC16P030993 GC16P031032 GC16P030905 GC16P030907 GC16P028558 |
Summaries
for HSD3B7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for HSD3B7:
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol anda member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associatedendoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this geneare associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressiveliver disease. Multiple transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq, Dec 2008)
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3Function: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroidsas substrates. Involved in bile acid synthesis
|
Genomic Views
for HSD3B7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HSD3B7 gene promoter:
c-Fos AhR AP-1 MIF-1 Arnt E47 Hand1 c-Jun Zic3 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for HSD3B7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSD3B7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2HSD3B7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P030997: view genomic region
(about GC identifiers)
Start:
|
30,996,519 bp from pter |
End:
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31,000,473 bp from pter |
Size:
|
3,955 bases |
Orientation:
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plus strand |
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Proteins
for HSD3B7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3 (See
protein sequence)Recommended Name: 3 beta-hydroxysteroid dehydrogenase type 7 Size: 369 amino acids; 41016 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: Q96M28 Q9BSN9Alternative splicing: 2 isoforms: Q9H2F3-1 Q9H2F3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for HSD3B7: NX_Q9H2F3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H2F3
HSD3B7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001136249.1 NP_001136250.1 NP_079469.2
ENSEMBL proteins: ENSP00000262520 ENSP00000297679 ENSP00000459852 ENSP00000459689 ENSP00000370662 Reactome Protein details: Q9H2F3
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
HSD3B7 for ontologies About GeneDecksing
HSD3B7 Antibody Products:
Assay Products for HSD3B7: |
Protein
Domains /
Families
for HSD3B7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
HSD3B7 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H2F3ProtoNet protein and cluster: Q9H2F3 1 Blocks protein family: IPB002225 3-beta hydroxysteroid dehydrogenase/isomerase
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3Similarity: Belongs to the 3-beta-HSD family |
Function
for HSD3B7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3Function: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroidsas substrates. Involved in bile acid synthesisCatalytic activity: 3-beta-hydroxy-Delta(5)-steroid + NAD(+) = 3-oxo-Delta(5)-steroid + NADHCatalytic activity: Cholest-5-ene-3-beta,7-alpha-diol + NAD(+) = 7-alpha-hydroxycholest-4-en-3-one + NADHEnzyme Numbers (IUBMB): EC 1.1.1.1811 EC 1.1.1.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): HSD3B7 (NM_001142777) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSD3B7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSD3B7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD3B7 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity |
NAS | 11067870 | | GO:0047016 | cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity |
IEA | -- |
HSD3B7 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for HSD3B7:
Animal Models:
Mouse knock-out Hsd3b7tm1Rus for HSD3B7
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Hsd3b7):
HSD3B7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for HSD3B7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of bile acids and bile salts | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for HSD3B7
5/7 
Reactome Pathways for HSD3B7 (see all 7)
2 
Kegg Pathways (Kegg details for HSD3B7):
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3Pathway: Lipid metabolism; steroid biosynthesis
HSD3B7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HSD3B7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/12 Interacting proteins for HSD3B7 (Q9H2F33 ENSP000002976794) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001558 | regulation of cell growth |
-- | -- | | GO:0006694 | steroid biosynthetic process |
-- | -- | | GO:0006699 | bile acid biosynthetic process |
TAS | -- | | GO:0008206 | bile acid metabolic process |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
HSD3B7 for ontologies About GeneDecksing
|
Drugs & Compounds
for HSD3B7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for HSD3B7
5 HMDB Compounds for HSD3B7 About this table
Search CenterWatch for drugs/clinical trials and news about HSD3B7 / 3BHS7
|
Transcripts
for HSD3B7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HSD3B7 gene (3 alternative transcripts): NM_001142777.1 NM_001142778.1 NM_025193.3 Unigene Cluster for HSD3B7: Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Hs.460618 [show with all ESTs]Unigene Representative Sequence: AL8343475 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262520(uc002eag.2 uc002eah.2) ENST00000297679(uc002eaf.2)
ENST00000562932 ENST00000574447 ENST00000353250(uc010cac.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): HSD3B7 (NM_001142777) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for HSD3B7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSD3B7 |
Additional cDNA sequence: AF277719.1 AK057436.1 AK290950.1 AK292068.1 AL834347.1 BC004929.1 6 DOTS entries: DT.443996 DT.95162070 DT.95162069 DT.100789904 DT.100789906 DT.100789900 24/90 AceView cDNA sequences (see all 90): F04463 BF001664 AI685254 F06983 CD369063 BF570301 NM_025193 BC004929 BM744211 BX379834 BM756534 BQ222554 BX352425 AW291942 AI308077 AI191086 BF337229 BE393409 AA514664 AA410523 AU279712 CA413388 AF277719 BQ689480
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for HSD3B7 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for HSD3B7
|
Expression
for HSD3B7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HSD3B7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGTTCCTGG
About this image
See HSD3B7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for HSD3B7
SOURCE GeneReport for Unigene cluster: Hs.460618
SABiosciences Custom PCR Arrays for HSD3B7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSD3B7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat HSD3B7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSD3B7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSD3B7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD3B7 |
Orthologs
for HSD3B7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for HSD3B7 gene from 6/18 species (see all 18) About this table
ENSEMBL Gene Tree for HSD3B7 (if available)
TreeFam Gene Tree for HSD3B7 (if available) |
Paralogs
for HSD3B7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for HSD3B7 gene
- SDR42E12 HSD3B22 SDR42E22 HSD3B12 NSDHL2
3 SIMAP similar genes for HSD3B7 using alignment to 3 protein entries: 3BHS7_HUMAN (see all proteins):HSD3B1 3-HSD 1 HSD3B2
HSD3B7 for paralogs About GeneDecksing
|
Genomic Variants
for HSD3B7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for HSD3B7 (30996519 - 31000473 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for HSD3B7
2 CNVs: 4942 4941
Human Gene Mutation Database (HGMD): HSD3B7
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSD3B7 |
|
Disorders
/ Diseases
for HSD3B7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HSD3B7 for disorders About GeneDecksing
OMIM gene information: 607764
OMIM disorders: 607765
UniProtKB/Swiss-Prot: 3BHS7_HUMAN, Q9H2F3
Defects in HSD3B7 are the cause of congenital bile acid synthesis defect type 1 (CBAS1) [MIM:607765]; alsoknown as neonatal progressive intrahepatic cholestasis. CBAS1 is due to a primary defect in bile synthesis leading toprogressive liver disease. Clinical features include neonatal jaundice, severe intrahepatic cholestasis and cirrhosis
13  diseases for HSD3B7: About MalaCardscongenital bile acid synthesis defect cholestasis cholestasis, progressive familial intrahepatic 4 liver disease
neonatal jaundice giant cell hepatitis intrahepatic cholestasis jaundice
cholesterol hepatitis tuberculosis neuronitis
mycobacterium tuberculosis
2 Novoseek disease relationships for HSD3B7 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cholestasis |
69.5 |
1 |
12679481 (1) |
| liver diseases |
40.5 |
4 |
12679481 (1), 17645593 (1) |
Human Genome Epidemiology (HuGE) Navigator: HSD3B7 (1 document)
Export disorders for HSD3B7 gene to outside databases
|
Publications
for HSD3B7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HSD3B7 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with HSD3B7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The bile acid synthetic gene 3beta-hydroxy-delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis. (PubMed id 11067870)1, 2, 3 Schwarz M....Russell D.W. (2000)
- Molecular genetics of 3beta-hydroxy-Delta5-C27-steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis and liver disease. (PubMed id 12679481)1, 2, 9 Cheng J.B....Russell D.W. (2003)
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Homozygosity mapping identifies a bile acid biosynthet ic defect in an adult with cirrhosis of unknown etiology. (PubMed id 22095780)1 Molho-Pessach V....Hobbs H.H. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Molecular genetic and bile acid profiles in two Japan ese patients with 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase defi ciency. (PubMed id 20531254)1 Mizuochi T....Matsuishi T. (2010)
- An integrative method for scoring candidate genes fro m association studies: application to warfarin dosing. (PubMed id 21044367)1 Tatonetti N.P....Altman R.B. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for HSD3B7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing HSD3B7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing HSD3B7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing HSD3B7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HSD3B7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for HSD3B7 gene:
Search GeneIP for patents involving HSD3B7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HSD3B7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for HSD3B7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for HSD3B7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSD3B7 | | | OriGene Protein Over-expression Lysate for HSD3B7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for HSD3B7 | | OriGene 3'-UTR Clone for HSD3B7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for HSD3B7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for HSD3B7 | | OriGene Custom Protein Services for HSD3B7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSD3B7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSD3B7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSD3B7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSD3B7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSD3B7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSD3B7 |
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| | | | Search Tocris compounds for HSD3B7 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD3B7 |
|  |  |  | | | | ThermoFisher Antibodies for HSD3B7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat HSD3B7 |
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