HSD17B7P2 Gene
pseudogene GIFtS: 29
GCID: GC10P038686
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hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
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Aliases
for HSD17B7P2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Hydroxysteroid (17-Beta) Dehydrogenase 7 Pseudogene 21 2 | | HSD17B71 2 | | BA291L22.11 | | Hsd17b_22 |
| External Ids: | HGNC: 281201 | Entrez Gene: 1581602 | Ensembl: ENSG000000992517 | | ORGUL members: | |
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| NONCODE:n405865 | |
Export aliases for HSD17B7P2 gene to outside databasesPrevious GC identifers: GC10U900126 GC10P038353
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Summaries
for HSD17B7P2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for HSD17B7P2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the HSD17B7P2 gene promoter:
AhR ER-alpha Sp1 HOXA3 GATA-3 CUTL1 LCR-F1 Arnt AREB6 COMP1
Other transcription factors
Search SABiosciences Chromatin IP Primers for HSD17B7P2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSD17B7P2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p11.1 Ensembl cytogenetic band: 10p11.1 HGNC cytogenetic band: 10p11.1HSD17B7P2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P038686: view genomic region
(about GC identifiers)
Start:
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38,645,305 bp from pter |
End:
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38,667,433 bp from pter |
Size:
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22,129 bases |
Orientation:
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plus strand |
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Proteins
for HSD17B7P2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for HSD17B7P2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for HSD17B7P2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD17B7P2 |
|
Pathways & Interactions
for HSD17B7P2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HSD17B7P2
|
Drugs & Compounds
for HSD17B7P2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
HSD17B7P2 for compounds About GeneDecksing
 Browse Tocris compounds for HSD17B7P2
5 Novoseek chemical compound relationships for HSD17B7P2 gene About this table
Search CenterWatch for drugs/clinical trials and news about HSD17B7P2 
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Transcripts
for HSD17B7P2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for HSD17B7P2 gene (2 alternative transcripts): NM_001031744.1 NM_182829.1 Unigene Cluster for HSD17B7P2: Hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2 Hs.652484 [show with all ESTs]Unigene Representative Sequence: BC0719875 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000494540(uc001izq.3) ENST00000471365 ENST00000356314 ENST00000374560(uc010qew.1 uc001izp.1)
ENST00000277668(uc010qex.1 uc001izo.1)
Additional cDNA sequence: AK295332.1 AK307174.1 BC071987.1 NR_003086.1 10 DOTS entries: DT.102827107 DT.95373297 DT.121292946 DT.100819444 DT.121292940 DT.121292945 DT.121292947 DT.95373298 DT.121292941 DT.40229952 24/42 AceView cDNA sequences (see all 42): BC071987 BQ352440 BX483879 AV660397 BG182213 AF165514 BG470748 BP346381 AL532435 AF165517 BU934909 CD238202 NM_182829 BX484674 AI874176 BG199997 BM148133 BF738124 AV691438 BE140115 AW806614 CD514563 BG426684 BP345692
GeneLoc Exon Structure
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Expression
for HSD17B7P2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| HSD17B7P2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for HSD17B7P2
SOURCE GeneReport for Unigene cluster: Hs.652484
SABiosciences Custom PCR Arrays for HSD17B7P2
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for HSD17B7P2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat HSD17B7P2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSD17B7P2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSD17B7P2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD17B7P2 |
Orthologs
for HSD17B7P2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for HSD17B7P2 (if available)
TreeFam Gene Tree for HSD17B7P2 (if available) |
Paralogs
for HSD17B7P2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for HSD17B7P2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for HSD17B7P2 (38645305 - 38667433 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for HSD17B7P2
1 CNV: 6861 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for HSD17B7P2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
HSD17B7P2 for disorders About GeneDecksing
4  diseases for HSD17B7P2: About MalaCardsbreast-ovarian cancer ovarian cancer breast cancer cholesterol
Export disorders for HSD17B7P2 gene to outside databases
|
Publications
for HSD17B7P2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for HSD17B7P2 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with HSD17B7P2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7. (PubMed id 10544267)1, 3, 9 Krazeisen A.... Adamski J. (1999)
- Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. (PubMed id 12829805)1, 9 Marijanovic Z....Breitling R. (2003)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Cloning and characterization of human form 2 type 7 17beta- hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme. (PubMed id 15862963)1 Liu H.... Luu-The V. (2005)
- Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7. (PubMed id 12732193)1 Toern S.... Vihko P. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Single nucleotide polymorphisms of 17beta-hydroxyster oid dehydrogenase type 7 gene: mechanism of estramustine-related adverse reacti ons? (PubMed id 19735314)9 Ozeki T....Yamada Y. (2009)
- Transcriptional regulation of human and murine 17beta-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis. (PubMed id 16901934)9 Ohnesorg T....Adamski J. (2006)
- Promoter analyses of human and mouse 17beta-hydroxysteroid dehydrogenase type 7. (PubMed id 15862973)9 Ohnesorg T. and Adamski J. (2005)
- Analysis of 17beta-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Cana dian Families with high risk of breast and ovarian cancer. (PubMed id 19460435)9 Plourde M....The V.L. (2009)
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External Searches for HSD17B7P2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing HSD17B7P2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing HSD17B7P2 gene
(According to HUGE)
About This Section
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Specialized Databases showing HSD17B7P2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for HSD17B7P2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for HSD17B7P2 gene:
Search GeneIP for patents involving HSD17B7P2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for HSD17B7P2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat HSD17B7P2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing HSD17B7P2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSD17B7P2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat HSD17B7P2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat HSD17B7P2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat HSD17B7P2 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for HSD17B7P2 |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat HSD17B7P2 |
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