Aliases for HSD17B7 Gene
- Hydroxysteroid 17-Beta Dehydrogenase 7 2 3 5
- Short Chain Dehydrogenase/Reductase Family 37C Member 1 3 4
- 17-Beta-Hydroxysteroid Dehydrogenase 7 3 4
- Estradiol 17-Beta-Dehydrogenase 7 3 4
- 17-Beta-HSD 7 3 4
- SDR37C1 3 4
- Short Chain Dehydrogenase/Reductase Family 37C, Member 1 2
- 17 Beta-Hydroxysteroid Dehydrogenase Type VII 3
External Ids for HSD17B7 Gene
Previous GeneCards Identifiers for HSD17B7 Gene
HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 126.96.36.199) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 188.8.131.520) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]
GeneCards Summary for HSD17B7 Gene
HSD17B7 (Hydroxysteroid 17-Beta Dehydrogenase 7) is a Protein Coding gene. Diseases associated with HSD17B7 include X-Linked Chondrodysplasia Punctata. Among its related pathways are cholesterol biosynthesis I and superpathway of steroid hormone biosynthesis. GO annotations related to this gene include oxidoreductase activity and estradiol 17-beta-dehydrogenase activity.
UniProtKB/Swiss-Prot for HSD17B7 Gene
Responsible for the reduction of the keto group on the C-3 of sterols.