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HSD17B14 Gene

protein-coding   GIFtS: 52
GCID: GC19M049316

Hydroxysteroid (17-Beta) Dehydrogenase 14

(Previous name: dehydrogenase/reductase (SDR family) member 10)
(Previous symbol: DHRS10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hydroxysteroid (17-Beta) Dehydrogenase 141 2     Short Chain Dehydrogenase/Reductase Family 47C1
DHRS101 2 3 5     17-Beta-Hydroxysteroid Dehydrogenase 142
Dehydrogenase/Reductase (SDR Family) Member 101 2     SDR47C12
Retinal Short-Chain Dehydrogenase/Reductase 31 2     retSDR32
Dehydrogenase/Reductase SDR Family Member 102 3     Short Chain Dehydrogenase/Reductase Family 47C, Member 12
Retinal Short-Chain Dehydrogenase/Reductase RetSDR32 3     EC 1.1.1.-3
17-Beta-HSD 142 3     SDR33
17-Beta-Hydroxysteroid Dehydrogenase DHRS102 3     RETSDR35
Member 11     

External Ids:    HGNC: 232381   Entrez Gene: 511712   Ensembl: ENSG000000870767   OMIM: 6128325   UniProtKB: Q9BPX13   

Export aliases for HSD17B14 gene to outside databases

Previous GC identifers: GC19M054009 GC19M045695


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for HSD17B14 Gene:
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the
C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al.,
2007 (PubMed 17067289)).(supplied by OMIM, Jun 2009)

GeneCards Summary for HSD17B14 Gene:
HSD17B14 (hydroxysteroid (17-beta) dehydrogenase 14) is a protein-coding gene. Diseases associated with HSD17B14 include estrogen-receptor positive breast cancer, and retinitis. GO annotations related to this gene include testosterone 17-beta-dehydrogenase (NADP+) activity and estradiol 17-beta-dehydrogenase activity. An important paralog of this gene is HPGD.

UniProtKB/Swiss-Prot: DHB14_HUMAN, Q9BPX1
Function: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The
physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the HSD17B14 gene promoter:
         GR   Max   RP58   GR-beta   Lmo2   GR-alpha   AP-4   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHSD17B14 promoter sequence
   Search Chromatin IP Primers for HSD17B14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSD17B14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.33

HSD17B14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSD17B14 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M049316:  view genomic region     (about GC identifiers)

Start:
49,316,274 bp from pter      End:
49,339,935 bp from pter
Size:
23,662 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DHB14_HUMAN, Q9BPX1 (See protein sequence)
Recommended Name: 17-beta-hydroxysteroid dehydrogenase 14  
Size: 270 amino acids; 28317 Da
Subunit: Homotetramer
1 PDB 3D structure from and Proteopedia for HSD17B14:
1YDE (3D)    
Secondary accessions: Q9UKU3

Explore the universe of human proteins at neXtProt for HSD17B14: NX_Q9BPX1

Explore proteomics data for HSD17B14 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HSD17B14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057330.2  
    ENSEMBL proteins: 
     ENSP00000263278   ENSP00000471631   ENSP00000472746   ENSP00000469557  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SDRC1: Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 1

    4 InterPro protein domains:
     IPR020904 Sc_DH/Rdtase_CS
     IPR002347 Glc/ribitol_DH
     IPR002198 DH_sc/Rdtase_SDR
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q9BPX1

    ProtoNet protein and cluster: Q9BPX1

    2 Blocks protein domains:
    IPB002198 Short-chain dehydrogenase/reductase SDR
    IPB002347 Glucose/ribitol dehydrogenase family signature


    UniProtKB/Swiss-Prot: DHB14_HUMAN, Q9BPX1
    Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family


    HSD17B14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHB14_HUMAN, Q9BPX1
    Function: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The
    physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro)

         Enzyme Number (IUBMB): EC 1.1.1.-1

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004303estradiol 17-beta-dehydrogenase activity IDA17067289
    GO:0005515protein binding IPI16189514
    GO:0016491oxidoreductase activity ----
    GO:0047045testosterone 17-beta-dehydrogenase (NADP+) activity IDA17067289
         
    HSD17B14 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for HSD17B14:
     Increased HPV18 LCR reporter a 

         1 MGI phenotypic allele for Hsd17b14 (no phenotypes)

    HSD17B14 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Hsd17b14tm1Lex for HSD17B14

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for HSD17B14
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    hsa-mir-26b-5p (MIRT030036)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DHB14_HUMAN, Q9BPX1: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol4
    mitochondrion2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005813centrosome ----
    GO:0005829cytosol IDA17067289

    HSD17B14 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HSD17B14
    Interactions:

        Search GeneGlobe Interaction Network for HSD17B14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for HSD17B14 (Q9BPX11, 2, 3 ENSP000002632784) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUDT18Q6ZVK81, 2, 3, ENSP000003078524EBI-742664,EBI-740486 MINT-67936 I2D: score=5 STRING: ENSP00000307852
    WDYHV1Q96HA81, 2, 3, ENSP000002873874EBI-742664,EBI-741158 MINT-66311 I2D: score=5 STRING: ENSP00000287387
    DDIT3P356382, 3, ENSP000003406714MINT-66282 I2D: score=5 STRING: ENSP00000340671
    PSMA1P257863I2D: score=1 
    HSD17B14Q9BPX12MINT-67795
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006706steroid catabolic process IDA17067289
    GO:0008152metabolic process ----
    GO:0044237cellular metabolic process ----

    HSD17B14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HSD17B14 (DHB14)

    1 HMDB Compound for HSD17B14    About this table
    CompoundSynonyms CAS #PubMed Ids
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for HSD17B14 gene: 
    NM_016246.2  

    Unigene Cluster for HSD17B14:

    Hydroxysteroid (17-beta) dehydrogenase 14
    Hs.18788  [show with all ESTs]
    Unigene Representative Sequence: BG165680
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263278(uc002pkv.1 uc010emk.1) ENST00000596349 ENST00000599157
    ENST00000595764
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat HSD17B14
      QuantiFast Probe-based Assays in human, mouse, rat HSD17B14

    Additional mRNA sequence: 

    AF126781.1 AK307437.1 AY358430.1 BC006283.2 BC006294.1 

    8 DOTS entries:

    DT.100024423  DT.92423917  DT.95274612  DT.121498457  DT.100024422  DT.100788304  DT.121498459  DT.95338366 

    Selected AceView cDNA sequences (see all 124):

    BM694804 AI985535 AA677354 BM547312 AV701940 AI308950 AI264270 AI379936 
    BM984680 BF112008 AI521441 CD369518 AI085468 CD368960 BU688227 AI373261 
    BC006294 BI829623 BF796973 AI244808 BM726898 AW135452 BC006283 BG768047 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for HSD17B14    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
    SP1:                    -                                                   
    SP2:                    -           -                                       
    SP3:                                -                                       
    SP4:                    -           -                 -                     
    SP5:                    -                             -                     


    ECgene alternative splicing isoforms for HSD17B14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HSD17B14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCAGCCCG
    HSD17B14 Expression
    About this image

    HSD17B14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HSD17B14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.18788

    UniProtKB/Swiss-Prot: DHB14_HUMAN, Q9BPX1
    Tissue specificity: Highly expressed in brain, placenta, liver and kidney

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for HSD17B14 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hsd17b141 , 5 hydroxysteroid (17-beta) dehydrogenase 141, 5 82.9(n)1
    81.78(a)1
      7 (29.35 cM)5
    660651  NM_025330.31  NP_079606.31 
     455548935 
    chicken
    (Gallus gallus)
    Aves HSD17B146
    hydroxysteroid (17-beta) dehydrogenase 14
    13(a)
    1 ↔ 1
    12(15571303-15598096)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    55(a)
    54(a)
    many → 1
    many → 1
    GL343355.1(726203-740750)
    GL343355.1(703301-714031)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.321392 Xenopus laevis transcribed sequence with weak similarity more 75.34(n)    BJ622274.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hsd17b141 hydroxysteroid (17-beta) dehydrogenase 14 58.76(n)
    58.19(a)
      445127  NM_001003521.2  NP_001003521.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0118521 AgaP_AGAP011852 48.78(n)
    37.5(a)
      1280798  XM_320665.4  XP_320665.4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G516801 AT3G51680 43.48(n)
    34.35(a)
      824331  NM_115027.1  NP_190736.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g06916001 Os07g0691600 51.17(n)
    40.79(a)
      4344372  NM_001067253.1  NP_001060718.1 


    ENSEMBL Gene Tree for HSD17B14 (if available)
    TreeFam Gene Tree for HSD17B14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HSD17B14 gene
    HPGD2  DCXR2  DECR22  CBR42  PECR2  DHRS22  HSD17B102  DHRS42  
    BDH22  DHRS4L22  HSD17B82  DECR12  
    7 SIMAP similar genes for HSD17B14 using alignment to 4 protein entries:     DHB14_HUMAN (see all proteins):
    CBR4    PECR    DECR1    DECR2    HSD17B10    BDH2
    SLC9B2

    HSD17B14 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HSD17B14 (see all 652)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs10453791,2
    C--49316428(-) GATTTC/TTCTCA 1 -- ut312Minor allele frequency- T:0.00MN NA 186
    rs1931979571,2
    C--49316438(+) CAGGAA/GGGGAT 2 P syn10--------
    rs1995946711,2
    --49316503(+) TGCACA/CCCCCG 2 G C mis10--------
    rs1457322471,2
    C--49316513(+) GTCACA/GAGCAG 2 L syn10--------
    rs3679571311,2
    C--49316620(+) AAAAG-/GGGGGG 1 -- int10--------
    rs2018548691,2
    C--49316653(+) CTTGAC/TCGCCA 1 -- int10--------
    rs2005453901,2
    --49316668(+) CCCCAA/CCCCCA 1 -- int10--------
    rs3745140621,2
    C--49316893(+) AGGAGA/GCTCTC 1 -- int10--------
    rs2000036071,2
    C--49316901(+) CTCCGC/TCTGCT 1 -- int10--------
    rs785358831,2
    C--49317098(+) CCCTCC/TTTGAA 1 -- int14Minor allele frequency- T:0.18NA WA EA 360

    HapMap Linkage Disequilibrium report for HSD17B14 (49316274 - 49339935 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for HSD17B14:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718692CNV Deletion23290073
    esv2431202CNV Deletion19546169
    esv2718691CNV Deletion23290073
    esv1431206CNV Insertion17803354
    nsv833855CNV Loss17160897
    esv6750CNV Loss19470904
    nsv912245CNV Loss21882294
    nsv9739CNV Gain+Loss18304495

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 612832    OMIM disorders: --

    5 diseases for HSD17B14:    
    About MalaCards
    estrogen-receptor positive breast cancer    retinitis    tuberculosis    breast cancer
    malaria

    1 disease from the University of Copenhagen DISEASES database for HSD17B14:
    estrogen-receptor positive breast cancer

    HSD17B14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): HSD17B14

    Export disorders for HSD17B14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for HSD17B14 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with HSD17B14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. (PubMed id 17067289)1, 2, 3 Lukacik P.... Oppermann U. (Biochem. J. 2007)
    2. Short-chain dehydrogenases/reductases in retina. (PubMed id 10800688)1, 2, 3 Haeseleer F. and Palczewski K. (Methods Enzymol. 2000)
    3. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (Chem. Biol. Interact. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. 17I^-Hydroxysteroid dehydrogenase type 14 is a predictive marker for tamoxifen response in oestrogen receptor positive breast cancer. (PubMed id 22792371)1 Sivik T....Jansson A. (PLoS ONE 2012)
    7. An empirical framework for binary interactome mapping. (PubMed id 19060904)1 Venkatesan K....Vidal M. (Nat. Methods 2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 51171 HGNC: 23238 AceView: DHRS10 Ensembl:ENSG00000087076 euGenes: HUgn51171
    ECgene: HSD17B14 H-InvDB: HSD17B14

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for HSD17B14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for HSD17B14 gene:
    Search GeneIP for patents involving HSD17B14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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