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HSD17B13 Gene

protein-coding   GIFtS: 45
GCID: GC04M088224

Hydroxysteroid (17-Beta) Dehydrogenase 13

  See HSD17B13-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Hydroxysteroid (17-Beta) Dehydrogenase 131 2     17-Beta Hydroxysteroid Dehydrogenase2
SCDR92 3 5     17-Beta-Hydroxysteroid Dehydrogenase 132
Short-Chain Dehydrogenase/Reductase 92 3     NIIL4972
17-Beta-HSD 132 3     SDR16C32
Member 31     Short Chain Dehydrogenase/Reductase Family 16C, Member 32
Short Chain Dehydrogenase/Reductase Family 16C1     EC 1.1.-.-3

External Ids:    HGNC: 186851   Entrez Gene: 3452752   Ensembl: ENSG000001705097   OMIM: 6121275   UniProtKB: Q7Z5P43   

Export aliases for HSD17B13 gene to outside databases

Previous GC identifers: GC00U991221 GC04M088583 GC04M088443 GC04M083970


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for HSD17B13 Gene:
HSD17B13 (hydroxysteroid (17-beta) dehydrogenase 13) is a protein-coding gene. Diseases associated with HSD17B13 include mucopolysaccharidosis iii, and endometrial carcinoma. GO annotations related to this gene include oxidoreductase activity. An important paralog of this gene is RDH10.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the HSD17B13 gene promoter:
         p53   AML1a   SREBP-1c   Cdc5   GATA-1   SREBP-1b   POU2F1   SREBP-1a   POU2F1a   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidHSD17B13 promoter sequence
   Search Chromatin IP Primers for HSD17B13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat HSD17B13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q22.1   Ensembl cytogenetic band:  4q22.1   HGNC cytogenetic band: 4q22.1

HSD17B13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSD17B13 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M088224:  view genomic region     (about GC identifiers)

Start:
88,224,941 bp from pter      End:
88,244,058 bp from pter
Size:
19,118 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DHB13_HUMAN, Q7Z5P4 (See protein sequence)
Recommended Name: 17-beta-hydroxysteroid dehydrogenase 13 precursor  
Size: 300 amino acids; 33655 Da
Secondary accessions: A8K9R9 Q2M1L5 Q86W22 Q86W23
Alternative splicing: 2 isoforms:  Q7Z5P4-1   Q7Z5P4-2   

Explore the universe of human proteins at neXtProt for HSD17B13: NX_Q7Z5P4

Explore proteomics data for HSD17B13 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See HSD17B13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129702.1  NP_835236.2  

    ENSEMBL proteins: 
     ENSP00000305438   ENSP00000333300  

    HSD17B13 Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online proteins for HSD17B13 (2 products) 

     
    antibodies-online peptides for HSD17B13

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    antibodies-online antibodies for HSD17B13 (13 products) 

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    antibodies-online kits for HSD17B13 (17 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SDRC3: Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 3

    3 InterPro protein domains:
     IPR002347 Glc/ribitol_DH
     IPR002198 DH_sc/Rdtase_SDR
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z5P4

    ProtoNet protein and cluster: Q7Z5P4

    1 Blocks protein domain: IPB002198 Short-chain dehydrogenase/reductase SDR

    UniProtKB/Swiss-Prot: DHB13_HUMAN, Q7Z5P4
    Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family


    Find genes that share domains with HSD17B13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 1.1.-.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0016491oxidoreductase activity IEA--
         
    Find genes that share ontologies with HSD17B13           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for HSD17B13:
     Increased HPV18 LCR reporter a 

         1 MGI phenotypic allele for Hsd17b13 (no phenotypes)

    Find genes that share phenotypes with HSD17B13           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Hsd17b13tm1Lex for HSD17B13

       genOway: Develop your customized and physiologically relevant rodent model for HSD17B13

    miRNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DHB13_HUMAN, Q7Z5P4: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    endoplasmic reticulum2
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with HSD17B13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for HSD17B13
    Interactions:

        Search GeneGlobe Interaction Network for HSD17B13

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for HSD17B13 (ENSP000003333004) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AP2M1ENSP000002928074STRING: ENSP00000292807
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0008152metabolic process ----

    Find genes that share ontologies with HSD17B13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for HSD17B13 (DHB13)

    Selected Novoseek inferred chemical compound relationships for HSD17B13 gene (see all 44)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    17beta-hydroxysteroid 98.6 252 8030703 (9), 8388710 (5), 8393406 (3), 10862262 (3) (see all 99)
    estrone 88.2 27 8388710 (4), 9361395 (2), 8380373 (1), 1309352 (1) (see all 22)
    3beta-hydroxysteroid 83.3 22 11375796 (2), 7892288 (1), 7747916 (1), 9059565 (1) (see all 21)
    androstenedione 82.8 17 2158194 (1), 7999680 (1), 11163318 (1), 9029727 (1) (see all 16)
    promegestone 80.7 2 10862262 (1), 7647331 (1)
    androstenediol 76.4 4 1390295 (1), 7821701 (1), 7546291 (1), 1314080 (1)
    androstanedione 75.8 1 1618995 (1)
    nomegestrol acetate 73.9 1 10862262 (1)
    testosterone 72.7 39 2158194 (2), 1618995 (2), 1325474 (1), 8380373 (1) (see all 28)
    estradiol 72.3 22 8380373 (1), 8388710 (1), 1309352 (1), 8125484 (1) (see all 21)



    Find genes that share compounds with HSD17B13           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for HSD17B13 gene (2 alternative transcripts): 
    NM_001136230.2  NM_178135.4  

    Unigene Cluster for HSD17B13:

    Hydroxysteroid (17-beta) dehydrogenase 13
    Hs.284414  [show with all ESTs]
    Unigene Representative Sequence: NM_178135
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302219 ENST00000328546(uc003hqo.2 uc010ikk.2)
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat HSD17B13
      QuantiFast Probe-based Assays in human, mouse, rat HSD17B13

    Additional mRNA sequence: 

    AB073347.1 AK292784.1 AY186249.1 AY186250.1 AY268355.1 AY358575.1 BC112303.1 BC112305.1 

    4 DOTS entries:

    DT.75124965  DT.97817522  DT.91690478  DT.100029823 

    Selected AceView cDNA sequences (see all 289):

    AA481430 AI888053 AW470979 AA577610 BU633600 CR603100 BQ025864 BG532267 
    BE465545 AA485827 AI954984 AY186249 CR607201 AA902413 CR590939 BM843043 
    AW337877 AY358575 AA481670 AW193089 AW051074 BM664111 AA292418 AB073347 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    HSD17B13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCTGCCCA
    HSD17B13 Expression
    About this image


    HSD17B13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Periportal Hepatocytes Liver Lobule
    HSD17B13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    HSD17B13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.284414

    UniProtKB/Swiss-Prot: DHB13_HUMAN, Q7Z5P4
    Tissue specificity: Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung,
    skeletal muscle, bladder and testis

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for HSD17B13 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Hsd17b131 , 5 hydroxysteroid (17-beta) dehydrogenase 131, 5 80(n)1
    82.11(a)1
      5 (50.46 cM)5
    2431681  NM_001163486.11  NP_001156958.11 
     1039554405 
    chicken
    (Gallus gallus)
    Aves SDR16C56
    Gallus gallus short chain dehydrogenase/reductase ...
    44(a)
    many ↔ many
    2(111004143-111017846)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    66(a)
    58(a)
    (see all 4)
    1 ↔ many
    1 ↔ many
    (see all 4)
    5(45327681-45345815)
    5(45282097-45293148)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia hsd17b131 hydroxysteroid (17-beta) dehydrogenase 13 63.75(n)
    63.87(a)
      496682  NM_001011240.1  NP_001011240.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-7k24.66
    si:dkey-7k24.6
    35(a)
    many ↔ many
    6(46395575-46411667) ENSDARG00000028862
    fruit fly
    (Drosophila melanogaster)
    Insecta CG156296
    CG92656
    --
    32(a)
    27(a)
    many ↔ many
    many ↔ many
    2L(4813009-4815891)
    2L(21057706-21071502)
    worm
    (Caenorhabditis elegans)
    Secernentea dhs-296
    Protein DHS-29 (dhs-29) mRNA, complete cds
    21(a)
    many ↔ many
    X(7661902-7664914) WBGene00000992
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TDA5(YLR426W)4 Putative protein of unknown function; detected in highly more   --   12(987062-988113) 851146  NP_013530.1 


    ENSEMBL Gene Tree for HSD17B13 (if available)
    TreeFam Gene Tree for HSD17B13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for HSD17B13 gene
    RDH102  HSD17B112  DHRS32  SDR16C52  
    4 SIMAP similar genes for HSD17B13 using alignment to 1 protein entry:     DHB13_HUMAN:
    HSD17B11    SDR16C5    DHRS3    RDH10

    Find genes that share paralogs with HSD17B13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for HSD17B13 (see all 533)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137389831,2
    C--88224443(+) GTTGGG/TAAGCT 2 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs43054861,2
    C,F,A,H--88224477(+) ATGTAT/CGGTAT 2 -- ds500120Minor allele frequency- C:0.18NA NS EA WA CSA 2001
    rs795172551,2
    F--88224478(+) TGTATG/AGTATG 2 -- ds50011Minor allele frequency- A:0.03WA 118
    rs284561441,2
    C,F--88224497(+) GATACG/AACCCA 2 -- ds50018Minor allele frequency- A:0.22NA WA EA 368
    rs1900820301,2
    --88224501(+) CGACCC/TATGCA 2 -- ds50010--------
    rs593951991,2
    C,F--88224584(+) CTCTGG/AGAAAT 2 -- ds50012Minor allele frequency- A:0.12WA NA 238
    rs1460502991,2
    C--88224680(+) TTACTC/GATAAA 2 -- ds50010--------
    rs76676691,2
    C,F,A,H--88224683(+) CTCATA/GAATTT 2 -- ds50017Minor allele frequency- G:0.08NS EA NA WA 598
    rs1388199281,2
    --88224739(+) ATTGCC/TGGTGA 2 -- ds50010--------
    rs583365411,2
    C,F--88224804(+) GGGTCA/GGTAAG 2 -- ds50013Minor allele frequency- G:0.12CSA WA NA 240

    HapMap Linkage Disequilibrium report for HSD17B13 (88224941 - 88244058 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for HSD17B13:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2667644CNV Deletion23128226
    nsv293508CNV Loss16902084
    nsv4412CNV Loss18451855
    nsv525583CNV Loss19592680
    nsv879527CNV Loss21882294
    nsv470050CNV Loss18288195
    nsv516203CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing HSD17B13
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612127    OMIM disorders: --

    4 diseases for HSD17B13:    
    About MalaCards
    mucopolysaccharidosis iii    endometrial carcinoma    meningioma    breast cancer


    Find genes that share disorders with HSD17B13           About GenesLikeMe

    Selected Novoseek inferred disease relationships for HSD17B13 gene (see all 16)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pseudohermaphroditism male 64.1 5 1325474 (2), 8393406 (2), 12797936 (1)
    virilization 57.5 5 9551369 (2), 9156049 (2), 9059565 (1)
    benign meningioma 48.4 2 7824086 (1), 8811669 (1)
    breast cancer 44.2 12 8380373 (2), 10862262 (2), 10226552 (2), 1728403 (1) (see all 9)
    choriocarcinoma 38.1 4 8005555 (2), 8030703 (2)
    breast carcinoma 32.8 3 8240985 (2), 8393337 (1)
    endometrial carcinoma 28.2 2 1325275 (1), 11096350 (1)
    prostate cancer 24.6 2 9256363 (2)
    benign prostatic hyperplasia 20.5 1 7490559 (1)
    mammary tumor 19.9 1 7749151 (1)


    Export disorders for HSD17B13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for HSD17B13 gene, integrated from 10 sources (see all 174):
    (articles sorted by number of sources associating them with HSD17B13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (Chem. Biol. Interact. 2009)
    2. Molecular cloning and expression analysis of a new gene for short- chain dehydrogenase/reductase 9. (PubMed id 17311113)1, 2 Liu S.... Yu L. (Acta Biochim. Pol. 2007)
    3. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (Oncogene 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (Int J Eat Disord 2013)
    7. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (PubMed id 22001757)1 Chambers J.C....Kooner J.S. (Nat. Genet. 2011)
    8. New gene functions in megakaryopoiesis and platelet formation. (PubMed id 22139419)1 Gieger C....Soranzo N. (Nature 2011)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 345275 HGNC: 18685 AceView: DHRS8andSCDR9 Ensembl:ENSG00000170509 euGenes: HUgn345275
    ECgene: HSD17B13 H-InvDB: HSD17B13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for HSD17B13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for HSD17B13 gene:
    Search GeneIP for patents involving HSD17B13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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