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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

HSD17B11 Gene

protein-coding   GIFtS: 56
GCID: GC04M088257

hydroxysteroid (17-beta) dehydrogenase 11

(Previous name: dehydrogenase/reductase (SDR family) member 8 )
(Previous symbol: DHRS8)
 Explore 10 diseases affiliated with
HSD17B11 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for HSD17B11    

Aliases
for HSD17B11 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Hydroxysteroid (17-Beta) Dehydrogenase 111 2     EC 1.1.1.623 8
PAN1B1 2 3 5     RETSDR22 5
DHRS81 2 3     RetSDR21
17-BETA-HSD111 2     17-Beta-Hydroxysteroid Dehydrogenase Type XI2
17-BETA-HSDXI1 2     17BHSD112
SDR16C21 2     CTCL Tumor Antigen HD-CL-032
Dehydrogenase/Reductase (SDR Family) Member 81 2     Estradiol 17-Beta-Dehydrogenase 112
Cutaneous T-Cell Lymphoma-Associated Antigen HD-CL-032 3     Short Chain Dehydrogenase/Reductase Family 16C, Member 22
Dehydrogenase/Reductase SDR Family Member 82 3     T-Cell Lymphoma-Associated Antigen HD-CL-032
Retinal Short-Chain Dehydrogenase/Reductase 22 3     17bHSD113
17-Beta-HSD 112 3     17betaHSD113
17-Beta-HSD XI2 3     17betaHSDXI3
17-Beta-Hydroxysteroid Dehydrogenase 112 3     RetSDR21
17-Beta-Hydroxysteroid Dehydrogenase XI2 3     EC 1.1.18
CTCL-Associated Antigen HD-CL-032 3     

External Ids:    HGNC: 229601   Entrez Gene: 511702   Ensembl: ENSG000001981897   OMIM: 6128315   UniProtKB: Q8NBQ53   

Export aliases for HSD17B11 gene to outside databases

Previous GC identifers: GC04M088477 GC04M084003


Summaries
for HSD17B11 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for HSD17B11:
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001
(PubMed 11165019)).(supplied by OMIM, Jun 2009)

UniProtKB/Swiss-Prot: DHB11_HUMAN, Q8NBQ5
Function: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may
participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid
synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or
A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen
in cutaneous T-cell lymphoma

Gene Wiki entry for HSD17B11


Genomic Views
for HSD17B11 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the HSD17B11 gene promoter:
         SRF   ISGF-3   AML1a   SRF (504 AA)   CREB   PPAR-alpha   SRY   deltaCREB   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: HSD17B11 promoter sequence
   Search SABiosciences Chromatin IP Primers for HSD17B11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat HSD17B11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q22.1   Ensembl cytogenetic band:  4q22.1   HGNC cytogenetic band: 4q22.1

HSD17B11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
HSD17B11 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M088257:  view genomic region     (about GC identifiers)

Start:
 88,257,691 bp from pter      End:
 88,312,538 bp from pter
Size:
 54,848 bases      Orientation:
 minus strand

Proteins
for HSD17B11 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DHB11_HUMAN, Q8NBQ5 (See protein sequence)
Recommended Name: Estradiol 17-beta-dehydrogenase 11 precursor  
Size: 300 amino acids; 32936 Da
Subcellular location: Secreted (Potential)
1 PDB 3D structure from and Proteopedia for HSD17B11:
1YB1 (3D)    
Secondary accessions: Q96HF6 Q9UKU4

Explore the universe of human proteins at neXtProt for HSD17B11: NX_Q8NBQ5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NBQ5

    • 4/6 DME Specific Peptides for HSD17B11 (Q8NBQ5) (see all 6)
     VLITGAG  TTKAFLP  VTVASAAGH  NTGFIKNPST 

    HSD17B11 Protein expression data from MOPED and PaxDb:    About this image 
    HSD17B11 Protein Expression
    REFSEQ proteins: NP_057329.2  
    ENSEMBL proteins: 
     ENSP00000351035   ENSP00000423775  

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    Browse Proteins at Uscn

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005737cytoplasm IDA12697717
    GO:0005811lipid particle IDA14741744

    HSD17B11 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for HSD17B11 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HSD17B11 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR002347 Glc/ribitol_DH
     IPR002198 DH_sc/Rdtase_SDR
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q8NBQ5

    ProtoNet protein and cluster: Q8NBQ5

    2 Blocks protein families:
    IPB002198 Short-chain dehydrogenase/reductase SDR
    IPB002347 Glucose/ribitol dehydrogenase family signature


    UniProtKB/Swiss-Prot: DHB11_HUMAN, Q8NBQ5
    Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily


    Function
    for HSD17B11 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DHB11_HUMAN, Q8NBQ5
    Function: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may
    participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid
    synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or
    A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen
    in cutaneous T-cell lymphoma
    Catalytic activity: 17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H

         Enzyme Numbers (IUBMB): EC 1.1.1.621 2 EC 1.1.12

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0004303estradiol 17-beta-dehydrogenase activity IEA--
    GO:0016229steroid dehydrogenase activity IDA12697717
    GO:0016491oxidoreductase activity ----
         
    HSD17B11 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for HSD17B11:
     Decreased number of cells in m  Synthetic lethal with c-Myc af 

    Animal Models:
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    hsa-miR-4261 hsa-miR-4289 hsa-miR-205 hsa-miR-1303 hsa-miR-202 hsa-miR-518a-5p
    SwitchGear 3'UTR luciferase reporter plasmid: HSD17B11 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Pathways & Interactions
    for HSD17B11 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1estrogen biosynthesis
    		estrogen biosynthesis1.00


    1 BioSystems Pathway for HSD17B11 
        estrogen biosynthesis


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for HSD17B11

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for HSD17B11 (Q8NBQ53 ENSP000003510354) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BRF2Q9HAW03, ENSP000002206594I2D: score=1 STRING: ENSP00000220659
    PTP4A3O753653, ENSP000003322744I2D: score=1 STRING: ENSP00000332274
    GSTK1Q9Y2Q33I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006694steroid biosynthetic process IEA--
    GO:0006710androgen catabolic process IDA12697717

    HSD17B11 for ontologies           About GeneDecksing



    Drugs & Compounds
    for HSD17B11 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for HSD17B11

    4 HMDB Compounds for HSD17B11    About this table
    CompoundSynonyms CAS #PubMed Ids
    Estradiol(+)-3,17b-Estradiol (see all 83)50-28-2--
    Estrone(+)-Estrone (see all 7)53-16-7--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    Testosterone(+)-testosterone (see all 86)58-22-0--

    1 DrugBank Compound for HSD17B11    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Aetiocholanolone-- 53-42-9target--10592235

    Search CenterWatch for drugs/clinical trials and news about HSD17B11 / DHB11 

    Transcripts
    for HSD17B11 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for HSD17B11 gene: 
    NM_016245.3  

    Unigene Cluster for HSD17B11:

    Hydroxysteroid (17-beta) dehydrogenase 11
    Hs.594923  [show with all ESTs]
    Unigene Representative Sequence: NM_016245
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358290(uc003hqp.2) ENST00000507518 ENST00000512344 ENST00000502576
    ENST00000507286 ENST00000513854 ENST00000508413

    miRNA
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    hsa-miR-4261 hsa-miR-4289 hsa-miR-205 hsa-miR-1303 hsa-miR-202 hsa-miR-518a-5p
    SwitchGear 3'UTR luciferase reporter plasmid: HSD17B11 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AF126780.1 AF273056.1 AK075348.1 AY358553.1 BC008650.1 BC011995.1 BC014327.1 BC016367.1 
    BC021673.1 BC036001.1 

    13 DOTS entries:

    DT.115882  DT.99986563  DT.100810454  DT.97845250  DT.121266831  DT.121266861  DT.121266867  DT.121266876 
    DT.95327715  DT.100029823  DT.40215765  DT.65285290  DT.75102880 

    24/289 AceView cDNA sequences (see all 289):

    CA842996 AB073347 AW273624 CB144012 BQ270992 CR590939 AW337877 AA394254 
    BQ773411 CR603100 CR598640 NM_178135 AY186250 CA775960 AI954984 AW193089 
    AY358575 AW051074 AA481674 BG290431 BG532267 AY186249 AA902413 BM664111 

    GeneLoc Exon Structure


    Expression
    for HSD17B11 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    HSD17B11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACTCTCAAT
    HSD17B11 Expression
    About this image

    HSD17B11 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See HSD17B11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for HSD17B11

    SOURCE GeneReport for Unigene cluster: Hs.594923

    UniProtKB/Swiss-Prot: DHB11_HUMAN, Q8NBQ5
    Tissue specificity: Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig
    cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated
    epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the
    nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein
    level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary
    and heart

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    In Situ
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    Orthologs
    for HSD17B11 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for HSD17B11 gene from 4/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves HSD17B111 hydroxysteroid (17-beta) dehydrogenase 11 64.83(n)
    64.95(a)    		   422588  XM_420547.2  XP_420547.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 4)    		 --
    		 65(a)
    58(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 5(45328317-45345268)
    5(45310675-45323840)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG156296
    CG149466
    (see all 6)    		 --
    		 32(a)
    31(a)
    (see all 6)    		 many ↔ many
    possible ortholog
    (see all 6)    		 2L(4813009-4815891)
    2L(12063523-12066772)
    worm
    (Caenorhabditis elegans)    		 Secernentea dhs-296
    		 DeHydrogenases, Short chain family member (dhs-29)...
    		 17(a)
    		 possible ortholog
    		 X(7661851-7664863)


    ENSEMBL Gene Tree for HSD17B11 (if available)
    TreeFam Gene Tree for HSD17B11 (if available) 

    Paralogs
    for HSD17B11 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for HSD17B11 gene
    HSD17B132  RDH102  DHRS32  SDR16C52  
    4 SIMAP similar genes for HSD17B11 using alignment to 2 protein entries:     DHB11_HUMAN (see all proteins):
    HSD17B13    DHRS3    RDH10    SDR16C5

    HSD17B11 for paralogs           About GeneDecksing



    Genomic Variants
    for HSD17B11 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1173 NCBI SNPs in HSD17B11 are shown (see all 1173)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 4 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1116499221,2
    		C,F--88257233(+) CCACAC/ACCAGC 1 -- ds50011Minor allele frequency- A:0.12NA 120
    rs1132890331,2
    		--88257248(+) GTTTGT/GGGATT 1 -- ds50012Minor allele frequency- G:0.28CSA WA 120
    rs1117801791,2
    		--88257341(+) AATCAT/GCCGCC 1 -- ds50012Minor allele frequency- G:0.30CSA WA 120
    rs1402217571,2
    		--88257347(+) CCGCCC/TGCCTT 1 -- ds50010--------
    rs1127761531,2
    		--88257436(+) GAGATG/AGAGTT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1884503111,2
    		--88257440(+) TGGAGC/TTTCAC 1 -- ds50010--------
    rs1449028491,2
    		--88257525(+) CAGGCA/GTGAGC 1 -- ds50010--------
    rs1134280081,2
    		--88257597(+) AACAAG/ACCTAC 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs576009151,2
    		C--88257720(+) AGGTTAA/-GTCAT 1 -- ut311Minor allele frequency- -:0.50CSA 2
    rs1461692581,2
    		--88257772(+) GTGTGA/GTCCAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for HSD17B11 (88257691 - 88312538 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for HSD17B11
         5 CNVs: 44173 6292 98786 22686 36311
         1 Indel: 46711

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    Disorders / Diseases
    for HSD17B11 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    HSD17B11 for disorders           About GeneDecksing

    OMIM gene information: 612831    OMIM disorders: --

    10 diseases for HSD17B11:    About MalaCards
    cutaneous t cell lymphoma    retinitis    alcoholism    intrahepatic cholangiocarcinoma
    cholangiocarcinoma    bronchiolitis    prostate cancer    prostatitis
    tuberculosis    mycobacterium tuberculosis


    Export disorders for HSD17B11 gene to outside databases

    Publications
    for HSD17B11 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for HSD17B11 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with HSD17B11)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. 17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells. (PubMed id 12697717)1, 2, 3, 9 Chai Z....Krozowski Z. (2003)
    2. Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung. (PubMed id 11165019)1, 2, 3 Brereton P.... Krozowski Z. (2001)
    3. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma. (PubMed id 14996095)1, 2 Hartmann T.B.... Eichmueller S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    8. Short-chain dehydrogenases/reductases in retina. (PubMed id 10800688)1, 2 Haeseleer F. and Palczewski K. (2000)
    9. Cloning and expression of a novel tissue specific 17beta- hydroxysteroid dehydrogenase. (PubMed id 9888557)1, 2 Li K.X.Z.... Krozowski Z.S. (1998)
    10. 17beta-hydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer. (PubMed id 19469652)1, 9 Nakamura Y....Sasano H. (2009)

    External Searches for HSD17B11 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing HSD17B11 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51170 HGNC: 22960 AceView: DHRS8andSCDR9 Ensembl:ENSG00000198189 euGenes: HUgn51170
    ECgene: HSD17B11 H-InvDB: HSD17B11

    Other Databases showing HSD17B11 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing HSD17B11 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for HSD17B11 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for HSD17B11 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for HSD17B11 gene:
    Search GeneIP for patents involving HSD17B11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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